Patents Represented by Attorney Paul D. Burgauer
  • Patent number: 4174342
    Abstract: By the addition of a relatively small amount of N-(acenaphthenyl)maleimides carrying optional substituents, synthetic films, plastics, woven or knitted synthetic or cellulosic fabrics, or paint can be protected against fungal and bacterial deterioration.
    Type: Grant
    Filed: March 27, 1978
    Date of Patent: November 13, 1979
    Assignee: Abbott Laboratories
    Inventors: Jorge P. Li, Frank C. Becker
  • Patent number: 4156684
    Abstract: Gibberellin A.sub.4 can be separated from the mixture of gibberellin A.sub.4 /A.sub.7 by placing a dilute aqueous mixture thereof at the pH of at least 9 for one day or more and subsequent adjustment of the pH to below 5.5, thereby precipitating substantially pure A.sub.4.
    Type: Grant
    Filed: March 13, 1978
    Date of Patent: May 29, 1979
    Assignee: Abbott Laboratories
    Inventor: Richard E. Crutcher
  • Patent number: 4151125
    Abstract: The addition of a 2-mercaptobenzamide to cutting fluid prevents bacterial and fungal growth.Concentrated solutions thereof in certain organic solvents are also disclosed. One such solution provides additional protection against corrosion of the metal surfaces.
    Type: Grant
    Filed: May 31, 1977
    Date of Patent: April 24, 1979
    Assignee: Abbott Laboratories
    Inventors: Jorge P. Li, John W. Williams
  • Patent number: 4151293
    Abstract: Compounds of the formula ##STR1## wherein R is phenyl, benzyl, 1-isopropylbenzyl wherein each of said aromatic rings may carry a chlorine substituent, ##STR2## R' is H, --C.tbd.N or --C.tbd.CH; R" is chlorine, bromine, fluorine or methyl; X and Y both but independently are H or loweralkyl; and Z is phenyl or benzyl which may carry an optional aromatic chlorine substituent, have been found to be excellent insecticides, ovicides and/or miticides.
    Type: Grant
    Filed: October 23, 1978
    Date of Patent: April 24, 1979
    Assignee: Abbott Laboratories
    Inventor: Robert G. Stein
  • Patent number: 4150125
    Abstract: A triglyceride carrying, in the .beta.-position, the anionic moiety of phosphonoacetic acid has been found to exhibit excellent activity against viral infections caused by a herpes virus.
    Type: Grant
    Filed: May 19, 1978
    Date of Patent: April 17, 1979
    Assignee: Abbott Laboratories
    Inventors: Thomas R. Herrin, John S. Fairgrieve
  • Patent number: 4141905
    Abstract: N-(2-Methyl-1-naphthyl) maleimide has been found to be a potent biocide capable of protecting fabrics, plastics, paints, etc. from fungal and/or bacterial attack.
    Type: Grant
    Filed: October 19, 1977
    Date of Patent: February 27, 1979
    Assignee: Abbott Laboratories
    Inventors: Frank C. Becker, Jorge P. Li
  • Patent number: 4141862
    Abstract: An excellent catalyst for polyurethane foams is a combination of 1, 3, 5-tris(3-dimethyl-aminopropyl)-s-hexahydrotriazine and 2-(dimethylamino)-ethanol. It has unexpectedly been found that this catalyst combination produces both excellent gelation and blowing reactions.
    Type: Grant
    Filed: October 25, 1977
    Date of Patent: February 27, 1979
    Assignee: Abbott Laboratories
    Inventors: Daniel S. Raden, Morton A. Weiner, Douglas W. Hill
  • Patent number: 4137317
    Abstract: Triglycerides carrying an anti-bacterial drug moiety in the 2-position and a hydrocarbon acyl moiety in the 1- and 3-positions exhibit excellent anti-bacterial properties without causing the side effects often associated with oral antibiotics when used by themselves.
    Type: Grant
    Filed: November 14, 1977
    Date of Patent: January 30, 1979
    Assignee: Abbott Laboratories
    Inventors: Gerald Y. Paris, Denis G. Cimon, David L. Garmaise
  • Patent number: 4130433
    Abstract: N-Phenoxyphenyl or N-phenylthiophenyl maleimides or 2,3-dichloromaleimides carrying optional substituents in the phenyl rings are potent biocides capable of protecting fabrics and plastics from fungal or bacterial attacks.
    Type: Grant
    Filed: June 10, 1977
    Date of Patent: December 19, 1978
    Assignee: Abbott Laboratories
    Inventors: Frank C. Becker, Jorge P. Li
  • Patent number: 4130434
    Abstract: Paint compositions containing an industrial biocide can be prevented from yellowing by the addition of a small amount of a certain mercury salt.
    Type: Grant
    Filed: November 21, 1977
    Date of Patent: December 19, 1978
    Assignee: Abbott Laboratories
    Inventor: Francis W. Arbir
  • Patent number: 4128529
    Abstract: By the addition of a relatively small amount of N-(phenoxyphenyl)maleimide or the corresponding 3,4-dichloromaleimide, synthetic films or plastics or woven or knitted synthetic or cellulosic fabrics can be protected against fungal and bacterial deterioration.
    Type: Grant
    Filed: April 8, 1977
    Date of Patent: December 5, 1978
    Assignee: Abbott Laboratories
    Inventors: Frank C. Becker, Jorge P. Li, John W. Williams
  • Patent number: 4122271
    Abstract: Protection against certain aquatic pests can be obtained by use of certain alkyl tin dithiocarbamates in the coating for materials exposed to such pests or the aquatic enivornment in contact with these materials.
    Type: Grant
    Filed: March 14, 1977
    Date of Patent: October 24, 1978
    Assignee: Abbott Laboratories
    Inventor: John Wesley Williams
  • Patent number: 4117014
    Abstract: Prostaglandin type compounds of the formula ##STR1## wherein X is --CH.sub.2 --CH.sub.2 --, --CH.dbd.CH-cis or--C.tbd.C--; Y is CH.sub.2 or O; Q is--CH.sub.2 --CH.sub.2 --or --CH.dbd.CH--; Z is H, OH, CH.sub.3 or CH.sub.2 OH, R is a linear, branched or cyclo alkyl chain of 3 to 7 carbon atoms or certain other moieties, and R" and R'''are H or CH.sub.3. These compounds are prepared by essentially a one-step reaction from a new intermediate of the formula ##STR2## wherein Z, R, R" and Q have the above meaning and P is a removable protective group by condensation with a reactive moiety introducing the entire .alpha.-chain (R'''=CH.sub.3). If desired, the carbonyl function is subsequently reduced to W= --CH(OH)--. The intermediate is useful in making known and new PGEs useful as antihypertensives, gastric acid secretion inhibitors and smooth muscle stimulants.
    Type: Grant
    Filed: December 23, 1976
    Date of Patent: September 26, 1978
    Assignee: Abbott Laboratories
    Inventors: Andre G. Pernet, Hiromasa Nakamoto, Naoyasu Ishizuka
  • Patent number: 4105788
    Abstract: This invention covers diacylated derivatives of .gamma.-glutamyl dopamine selected from the group consisting of ##STR1## where R is a C.sub.1 -C.sub.12 straight or branched chain alkyl radical, a phenyl ring or a substituted phenyl ring and R' is H or a C.sub.1 -C.sub.7 alkyl, and a pharmaceutically acceptable acid addition salt thereof.The compounds of this invention are useful to increase the renal blood flow by being administered to warm-blooded animals by clinically accepted routes of administration such as oral, parenteral, rectal and the like.
    Type: Grant
    Filed: May 3, 1977
    Date of Patent: August 8, 1978
    Assignee: Abbott Laboratories
    Inventors: Peter H. Jones, Carroll W. Curs, Jaroslav Kyncl
  • Patent number: 4105787
    Abstract: This invention covers diacylated derivatives of .gamma.-glutamyl dopamine selected from the group consisting of ##STR1## where R is a C.sub.1 -C.sub.12 straight or branched chain alkyl radical, a phenyl ring or a substituted phenyl ring and R' is H or a C.sub.1 -C.sub.7 alkyl, and a pharmaceutically acceptable acid addition salt thereof.The compounds of this invention are useful to increase the renal blood flow by being administered to warm-blooded animals by clinically accepted routes of administration such as oral, parenteral, rectal and the like.
    Type: Grant
    Filed: May 3, 1977
    Date of Patent: August 8, 1978
    Assignee: Abbott Laboratories
    Inventors: Peter H. Jones, Carroll W. Curs, Jaroslav Kyncl
  • Patent number: 4104306
    Abstract: A new chemical compound, the 12a-deoxychelocardin has been synthesized and found to be a potent antibacterial. It can also be used as an intermediate for the preparation of a number of modified chelocardin analogs that are similarly active as antibacterials, e.g. the compounds carrying different substituents in the D-ring.
    Type: Grant
    Filed: May 5, 1976
    Date of Patent: August 1, 1978
    Assignee: Abbott Laboratories
    Inventors: Edith Bernstein, Daniel Tim-Wo Chu, Stuart Nicholas Huckin
  • Patent number: 4103091
    Abstract: This invention provides intermediates which are essential for a new chemical method which converts terrein, a fungal metabolite, to an intermediate which is known to be useful for the preparation of prostaglandins of the C series and analogs of other prostaglandins.
    Type: Grant
    Filed: July 22, 1976
    Date of Patent: July 25, 1978
    Assignee: The Ohio State University Research Foundation
    Inventors: Lester Allen Mitscher, George Winfred Clark, III, Gordon Herman Bokelman
  • Patent number: 4097597
    Abstract: A compound represented by the formula ##STR1## wherein R is H, loweralkyl, hydroxyloweralkyl or ##STR2## where R.sub.2 is an alkyl group of 1 to 15 carbon atoms; and R.sub.1 is H or ##STR3## where R.sub.2 is an alkyl group of 1 to 15 carbon atoms. These compounds are useful as antischizophrenics.
    Type: Grant
    Filed: February 23, 1977
    Date of Patent: June 27, 1978
    Assignee: Abbott Laboratories
    Inventors: Bruce Wayne Horrom, Frederick Nelson Minard, Harold Elmer Zaugg
  • Patent number: 4096261
    Abstract: This invention provides dibenzodiazepines represented by the formula ##STR1## wherein R is ##STR2## The compounds of this invention are useful as antischizophrenics.
    Type: Grant
    Filed: February 23, 1977
    Date of Patent: June 20, 1978
    Assignee: Abbott Laboratories
    Inventors: Bruce Wayne Horrom, William Douglas Barta
  • Patent number: RE29732
    Abstract: The new blocked tripeptide Y-(N.sup.w -R')Arg-Pro-Gly-R wherein R is .[.hydroxy, methoxy or.]. amino, R' is a suitable blocking group and Y is hydrogen or an easily removable protective group has been found to be a valuable intermediate for the preparation of large peptide chains, such as for instance, the decapeptide Gn-RH.
    Type: Grant
    Filed: January 31, 1977
    Date of Patent: August 15, 1978
    Assignee: Abbott Laboratories
    Inventor: George Rogelio Flouret