Patents Represented by Attorney Paul D. Burgauer
  • Patent number: 4092412
    Abstract: A method of treating herpes simplex infections in warm-blooded animals by administering to said animals a carboxylic ester of phosphonoacetic acid of the formula ##STR1## wherein R is a C.sub.1 -C.sub.2 alkyl.
    Type: Grant
    Filed: April 14, 1977
    Date of Patent: May 30, 1978
    Assignee: Abbott Laboratories
    Inventors: James Chieh-Hsia Mao, John Hunter Seely, John Scott Fairgrieve
  • Patent number: 4092433
    Abstract: Covers a method for the control of mollusks by treating said mollusk or its habitat with a compound of the formula: ##STR1## where Z is selected from the group consisting of hydrogen, halo and cyano; X is selected from the group consisting of ##STR2## and Y is selected from the group consisting of halo, loweralkyl, aziridino, hydrogen, carboxyalkylthio, and cyano.
    Type: Grant
    Filed: November 10, 1976
    Date of Patent: May 30, 1978
    Assignee: Abbott Laboratories
    Inventor: Aldo Joseph Crovetti
  • Patent number: 4087528
    Abstract: This invention provides 2,4-diamino-5-benzylpyrimidines represented by the formula ##STR1## wherein R.sub.1 is H or loweralkyl; R.sub.2 is H, loweralkyl or R.sub.3 CO-- wherein R.sub.3 is H, alkyl, or cycloalkyl-lowerakyl; and X is a halogen; and the acid addition salts thereof.These pyrimidine compounds are useful as antibacterial agents, and as potentiators of the anti-bacterial activity of sulfonamides.
    Type: Grant
    Filed: October 26, 1976
    Date of Patent: May 2, 1978
    Assignee: Abbott Laboratories
    Inventors: Thomas John Perun, Ronald Robert Rasmussen, Bruce Wayne Horrom
  • Patent number: 4083868
    Abstract: A compound of the formula ##STR1## wherein R is a C.sub.6 -C.sub.20 alkyl, arylalkyl or cycloalkyl alkyl; R' is phenyl or substituted phenyl; and X is H, halogen,N(R").sub.2where R" is H or C.sub.1 -C.sub.7 alkyl, or a group represented by the formula ##STR2## WHERE N IS AN INTEGER FROM 1 TO 4; M IS AN INTEGER FROM 1 TO 4; AND Y is CH.sub.2, O, S or NR"' where R"' is H or C.sub.1 -C.sub.7 alkyl.The compounds of this invention are useful as intraocular pressure lowering agents, i.e., anti-glaucoma agents.
    Type: Grant
    Filed: August 16, 1976
    Date of Patent: April 11, 1978
    Assignee: Abbott Laboratories
    Inventors: Harold Elmer Zaugg, Cheuk Man Lee
  • Patent number: 4080343
    Abstract: The use of catalytic amounts of pentamethyldipropylenetriamine promotes the formation of urethane links. Its unusual activity and properties makes the new compound very useful in the manufacture of flexible and rigid polyurethanes.
    Type: Grant
    Filed: September 22, 1976
    Date of Patent: March 21, 1978
    Assignee: Abbott Laboratories
    Inventor: Daniel S. Raden
  • Patent number: 4078888
    Abstract: 4-Tolyl diiodomethyl sulfone has been found to protect leather from fungal attack if it is incorporated into the tanning mixture in suitable amounts.
    Type: Grant
    Filed: September 20, 1976
    Date of Patent: March 14, 1978
    Assignee: Abbott Laboratories
    Inventors: Francis Walter Arbir, Frank Carl Becker
  • Patent number: 4076804
    Abstract: This invention is directed to the method of combatting erythromycin sensitive bacteria in warm-blooded animals without restricting their food intake.
    Type: Grant
    Filed: December 13, 1976
    Date of Patent: February 28, 1978
    Assignee: Abbott Laboratories
    Inventors: Robert E. Singiser, Alexander Hing Chinn Chun, Shashi Pal Mehta
  • Patent number: 4071533
    Abstract: Compounds of the formula ##STR1## and X is hydrogen, halo, alkyl, cyano or nitro, Y is oxygen or sulfur and R is lower alkyl, have been found to be excellent pesticides.
    Type: Grant
    Filed: March 11, 1976
    Date of Patent: January 31, 1978
    Assignee: Abbott Laboratories
    Inventors: Robert George Stein, Terry Lee Couch
  • Patent number: 4071622
    Abstract: Certain nonapeptide amides were found which, upon administration at daily dosages of from about 1-200 .mu.g/kg to warm-blooded animals, cause regression of DMBA-inducible or mammary tumors without causing adverse effects on healthy tissues.
    Type: Grant
    Filed: February 11, 1976
    Date of Patent: January 31, 1978
    Assignee: Abbott Laboratories
    Inventors: Edwin Samuel Johnson, John Hunter Seely
  • Patent number: 4064142
    Abstract: Biodegradable insecticides having the formula: ##STR1## where X, Y and R are different, and X and Y are selected from the group consisting of hydrogen, halo, lower alkyl and lower alkoxy, and R is selected from the group consisting of nitrogen, oxygen, sulfur and sulfone.
    Type: Grant
    Filed: September 3, 1976
    Date of Patent: December 20, 1977
    Assignee: Abbott Laboratories
    Inventors: Robert George Stein, Terry Lee Couch, Aldo Joseph Crovetti
  • Patent number: 4063014
    Abstract: A 4"-O-sulfonyl erythromycin derivative of the following structural formula: ##STR1## where R is selected from the group consisting of oxygen, oxime, and substituted oxime, R.sub.1 is hydrogen or hydroxy and R.sub.2 is selected from the group consisting of phthalimide, substituted amides, benzamides, substituted benzamides, sulfonamides, substituted sulfonamides, amines, substituted amines, phenylurea, substituted phenylurea, phenylthiourea, substituted phenylthiourea, thiophenol and substituted thiophenol, phenoxides and substituted phenoxides and R.sub.3 is hydrogen or methyl. The present sulfonyl derivatives of erythromycin A, B and C are useful as antibiotics.
    Type: Grant
    Filed: June 12, 1975
    Date of Patent: December 13, 1977
    Assignee: Abbott Laboratories
    Inventors: Robert Hallas, Jerry Roy Martin, John Soloman Tadanier
  • Patent number: 4051190
    Abstract: A two-step preparation of 3-arylpropyl chloride from the corresponding 2-chloropropiophenone by hydrogenation using two specific catalysts in series.
    Type: Grant
    Filed: January 30, 1976
    Date of Patent: September 27, 1977
    Assignee: Abbott Laboratories
    Inventor: Daniel Ambrose Dunnigan
  • Patent number: 4046887
    Abstract: Triglycerides carrying hydrocarbon acyl moieties in the 1- and 3-positions and the 2-methyl-1,3-benzodioxan-4-on-2-yl moiety in the 2-position exhibit excellent anti-inflammatory properties.
    Type: Grant
    Filed: October 28, 1976
    Date of Patent: September 6, 1977
    Assignee: Abbott Laboratories
    Inventors: Gerard Yvon Paris, Denis Gaston Cimon
  • Patent number: 4046892
    Abstract: A limited class of novel compounds, the 7-aza-11,12-dioxa-6-phenyl-tricyclo[7,2,1,0.sup.1.6 ]dodecanes carrying an optional alkyl substituent in the 7-position, has been found highly useful as injection anesthetics.
    Type: Grant
    Filed: March 24, 1976
    Date of Patent: September 6, 1977
    Assignee: Abbott Laboratories
    Inventor: Edward John Warawa
  • Patent number: 4034082
    Abstract: With the administration of 1 .mu.g - 10mg/kg of specified nonapeptides, reproduction is prevented in warm-blooded animals of the reproductive age.
    Type: Grant
    Filed: March 1, 1976
    Date of Patent: July 5, 1977
    Assignee: Abbott Laboratories
    Inventors: Edwin Samuel Johnson, Wilfrid Francis White
  • Patent number: 4033997
    Abstract: Excellent results have been obtained by reacting N-carboxyanhydrides of aminoacids with dopamine. This new route for making aminoacid derivatives of dopamine is advantageous as the aminoacid needs no blocking of the amino group and therefore no additional reaction step for the removal of such a blocking group.
    Type: Grant
    Filed: February 26, 1976
    Date of Patent: July 5, 1977
    Assignee: Abbott Laboratories
    Inventor: Robert Roteman
  • Patent number: 4025531
    Abstract: Biodegradable insecticides having the formula: ##STR1## where X, Y and R are different, and X and Y are selected from the group consisting of hydrogen, halo, lower alkyl and lower alkoxy, and R is selected from the group consisting of nitrogen, oxygen, sulfur and sulfone.
    Type: Grant
    Filed: April 7, 1975
    Date of Patent: May 24, 1977
    Assignee: Abbott Laboratories
    Inventors: Robert George Stein, Terry Lee Couch, Aldo Joseph Crovetti
  • Patent number: 4025499
    Abstract: A process for preparing a peptide with His or 3-Me-His at the C-terminus wherein the coupling with said His or (3-Me) His is carried out in the presence of triethylamine.
    Type: Grant
    Filed: November 3, 1975
    Date of Patent: May 24, 1977
    Assignee: Abbott Laboratories
    Inventor: Alford Mitchell Thomas
  • Patent number: 4025654
    Abstract: A dry chelocardin salt composition which is stable to extended storage periods comprises a mixture of monosodium chelocardin and between 0.2 and 2.0 parts of sodium citrate.
    Type: Grant
    Filed: December 17, 1975
    Date of Patent: May 24, 1977
    Assignee: Abbott Laboratories
    Inventor: Bahram Farhadieh
  • Patent number: 4018914
    Abstract: Certain nonapeptides have been found to induce parturition in warm-blooded animals if administered within the last phase of pregnancy.
    Type: Grant
    Filed: November 13, 1975
    Date of Patent: April 19, 1977
    Assignee: Abbott Laboratories
    Inventor: Edwin Samuel Johnson