Patents Represented by Attorney Paul J. Cook

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  • Spiral wound filtration membrane cartridge
    Patent number: 5128037
    Abstract: A spiral wound filtration cartridge construction is provided which includes a cartridge positioned within a solid outer cylinder which, in turn is positioned within a solid housing. Fluid flow within the space between the outer cylinder and housing is controlled by an end plate construction. The rigid solid end plate construction includes outer peripheral holes, the sizes and number of which are set to determine by-pass flow.
    Type: Grant
    Filed: December 27, 1990
    Date of Patent: July 7, 1992
    Assignee: Millipore Corporation
    Inventors: Steven R. Pearl, Peter M. Dansky
  • Process and apparatus for proportioning liquids
    Patent number: 5127542
    Abstract: A proportioning process and apparatus is provided for forming a liquid composition by admixture of a plurality of liquid components. The apparatus includes a main chamber, a subchamber positioned within the main chamber and conduits for introducing the liquid components sequentially into the subchamber which then overflow into the main chamber. The main chamber and subchamber are provided with outlets so that the liquid therein can be admixed to form the liquid composition. A pressure sensor in the subchamber is provided to measure the head pressure of each component in the subchamber and the main chamber which, because the dimensions of the subchamber and main chamber are known, can be used to measure the volumes of the liquid components to be admixed. A level sensor is provided at the top of the main chamber to be used as a calibration point and for overflow detection.
    Type: Grant
    Filed: August 1, 1990
    Date of Patent: July 7, 1992
    Assignee: Millipore Corporation
    Inventors: Laura L. Deming, Gaston de los Reyes
  • Method and apparatus for effecting capillary electrophoresis fraction collection on a membrane
    Patent number: 5126025
    Abstract: A sample is injected into a capillary tube of a capillary electrophoresis apparatus. A sample solute on a porous layer is positioned in contact with an entrance end of the capillary tube and electrodes are positioned at the entrance end and exit end of the tube. The separated sample is collected at the exit end of the tube.
    Type: Grant
    Filed: August 30, 1990
    Date of Patent: June 30, 1992
    Assignee: Millipore Corporation
    Inventors: William W. Carson, Yung-Fong Cheng, Martin Fuchs
  • Fluid delivery system
    Patent number: 5123443
    Abstract: A fluid delivery system is provided to deliver precise volumes of a plurality of fluids in sequence to a treatment reservoir. Fluid channels are formed in a plate structure to provide a means for delivering fluids from a plurality of fluid reservoirs to one or a plurality of treatment reservoirs. Each fluid is delivered by a system comprising a check valve in fluid communication with a fluid reservoir, a positive displacement pump in fluid communication with the check valve and an injector in fluid communication with the positive displacement pump. A partition valve is provided to direct fluid to the desired treatment reservoirs.
    Type: Grant
    Filed: December 21, 1990
    Date of Patent: June 23, 1992
    Assignee: Millipore Corporation
    Inventor: Brevard S. Garrison
  • Ferrous dithionite process and compositions for removing dissolved heavy metals from water
    Patent number: 5122279
    Abstract: Heavy metal ions react with ferrous dithionite in acidic aqueous solution. They are reduced to metallic particles that are suitable for recycling and reuse when recovered from the acidic water. When chelating agents are present, they are deactivated by bonding to the ferrous ions. Ferrous dithionite, (FeS.sub.2 O.sub.4) is either generated in-situ or ferrous ions and dithionite ions can be provided by other methods.
    Type: Grant
    Filed: April 8, 1991
    Date of Patent: June 16, 1992
    Assignee: Romar Technologies Inc.
    Inventor: Robert G. Guess
  • Method and apparatus for effecting capillary sample injection into electrophoresis apparatus
    Patent number: 5120414
    Abstract: An electrode structure is provided for feeding a solute sample to a capillary electrophoresis separation process. The apparatus comprises a conductive plate connected to an electrical lead and an absorbent layer wet with an electrolyte solution and positioned on the plate. A membrane containing a sample is positioned on the absorbent layer in contact with an entrance end of a capillary tube forming part of the separation process. The sample is fed to the entrance part by electromigration and/or electrosmosis under the influence of an electric field induced by an electrode.
    Type: Grant
    Filed: August 30, 1990
    Date of Patent: June 9, 1992
    Assignee: Millipore Corporation
    Inventors: William W. Carson, Yung-Fong Cheng
  • Electrodeionization and ultraviolet light treatment method for purifying water
    Patent number: 5116509
    Abstract: A process is provided for removing organics and ions from liquid. Water to be purified is first exposed to ultraviolet(UV) radiation to oxidize organics in the liquid. The UV-treated water then is passed through an electrodeionization apparatus having an ion depletion compartment containing mixed anion and cation exchange resin beads and an ion concentration compartment in a given separation stage having an anode and a cathode. A second liquid is passed through the concentration compartment which is free of or filled with ion exchange resin beads. Ions under the influence of D.C. potential pass from the depletion compartments into the concentration compartments through ion permeable membranes. The electrodeionization apparatus can be operated continuously in conjunction with the UV radiation step since resin regeneration is not required.
    Type: Grant
    Filed: September 8, 1989
    Date of Patent: May 26, 1992
    Assignee: Millipore Corporation
    Inventor: Janet White
  • Fluid seal
    Patent number: 5114161
    Abstract: A sealing means is provided that may be used, among other things, for sample injection apparatus used in liquid chromatography. The seal includes a jacket having a central bore through which a hypodermic needle containing a sample is inserted. The jacket includes a U-shaped cross section having an inner axial surface and an outer axial surface. Metal cylindrical bands which function as springs are positioned tightly against the inner and outer axial surfaces respectively. Each band has a slot extending through its thickness and along its entire axial length.
    Type: Grant
    Filed: March 20, 1991
    Date of Patent: May 19, 1992
    Assignee: Millipore Corporation
    Inventors: George E. Sgourakes, Stanislaw Koziol
  • Tough polymer compositions
    Patent number: 5115028
    Abstract: Polymer blends are provided comprising a glassy thermoplastic polymer having a glass transition temperature above ambient conditions, e.g., normal room temperature and between 0.1 and 4.0 weight percent of a rubbery polymer having a glass transition temperature below ambient temperature conditions, e.g., normal room temperature based on the weight of the blend. The blends can be produced by solution casting or by coagulation from solution followed by flocculation.
    Type: Grant
    Filed: January 31, 1990
    Date of Patent: May 19, 1992
    Assignee: Massachusetts Institute of Technology
    Inventors: Osman S. Gebizlioglu, Robert E. Cohen, Ali S. Argon, Haskell W. Beckham, Jian Qin
  • Filter membrane support and filtration funnel
    Patent number: 5112488
    Abstract: The instant invention provides a support apparatus for a filter membrane which comprises a central porous support section and a peripheral support section, said central porous support section adapted to support a central portion of a filter membrane and said peripheral support section adapted to support a peripheral portion of a filter membrane, a base support for said central support section and said peripheral support section, and means to separate said central porous support section from said peripheral support action thereby to separate said peripheral portion of said filter membrane from said peripheral support section.
    Type: Grant
    Filed: June 17, 1991
    Date of Patent: May 12, 1992
    Assignee: Millipore Corporation
    Inventor: Jean Lemonnier
  • Partition valve for fluid delivery system
    Patent number: 5111845
    Abstract: A partition valve for use in a fluid delivery system is provided to deliver precise volumes of plurality of fluids in sequence to a plurality of treatment reservoirs. The partition valve includes a diaphragm having a top surface in contact with a plurality of fluid pressure sources. The bottom surface of the diaphragm contacts a plurality of fluid inlets and outlets. The fluid pressure sources are controlled to effect fluid communication between desired fluid inlets and fluid outlets.
    Type: Grant
    Filed: December 21, 1990
    Date of Patent: May 12, 1992
    Assignee: Millipore Corporation
    Inventor: Brevard S. Garrison
  • Torso harness
    Patent number: 5101768
    Abstract: An adjustable torso harness strap is provided with a quick-release snap buckle and a two-segment adjustable chest strap having a quick-release snap buckle. One segment of the chest strap is permanently secured to the torso harness strap. The second segment of the chest strap is slideably secured to the torso harness strap. The strap is worn by one individual rescuer to assist in the physical evacuation of one individual rescuee by positioning the portion of the harness strap above the chest strap over the shoulders of the rescuer and around the back of the rescuee. The portion of the harness strap below the chest strap is positioned under the shoulders of the rescuer and around the back of the upper-portion of the legs of the rescuee. The chest strap is positioned across the chest of the rescuer.
    Type: Grant
    Filed: August 11, 1988
    Date of Patent: April 7, 1992
    Inventor: Charles Cates
  • Tangential flow filtration apparatus
    Patent number: 5096582
    Abstract: A tangential flow filtration apparatus which utilizes a single manifold to introduce liquid to be filtered into the apparatus and to remove a filtrate stream and a retentate stream from the apparatus is provided. A plurality of filtration members are stacked in a vertical arrangement between the manifold and a plate. Holes and sealing means are provided within the filtration member to effect vertical flow of the filtrate, retentate and incoming liquid through the stack while preventing admixture of the filtrate with the retentate or the incoming liquid.
    Type: Grant
    Filed: September 25, 1990
    Date of Patent: March 17, 1992
    Assignee: Millipore Corporation
    Inventors: Andrew A. Lombardi, James H. Edwards
  • Injector for fluid delivery system
    Patent number: 5095938
    Abstract: An injector for a fluid delivery system is provided to deliver precise volumes of a plurality of fluids in sequence to a treatment reservoir. The injector is in fluid communication with a positive displacement pump which accepts fluid from a fluid source. The injector includes a spring loaded plunger, an end of which contacts a diaphragm adapted to seal an injector inlet from an injector outlet. The end of the plunger is shaped to seat the diaphragm against the injector outlet and to position the diaphragm away from the injector inlet.
    Type: Grant
    Filed: December 21, 1990
    Date of Patent: March 17, 1992
    Assignee: Millipore Corporation
    Inventor: Brevard S. Garrison
  • Membrane, process and system for isolating virus from solution
    Patent number: 5096637
    Abstract: A composite membrane and process utilizing the membrane which is capable of selectively removing particles such as viral particles from a solution such as a protein solution is provided. The membrane comprises a porous membrane substrate, a surface skin having ultrafiltration separation properties and an intermediate porous zone between the substrate and the skin which intermediate zone has an average pore size smaller than that of the substrate. The intermediate zone is free of voids which break the skin and which directly fluid communicate with the substrate. The composite is capable of a log reduction value of at least 3 (99.9% removal) of particles selectively from solution.
    Type: Grant
    Filed: December 5, 1990
    Date of Patent: March 17, 1992
    Assignee: Millipore Corporation
    Inventors: Anthony J. DiLeo, Anthony E. Allegrezza, Edmund T. Burke
  • Check valve for fluid delivery system
    Patent number: 5095932
    Abstract: A check valve for use in a fluid delivery system is provided to deliver precise volumes of a plurality of fluids in sequence to a treatment reservoir. The check valve is in fluid communication with a positive displacement pump and with fluid reservoir. The check valve includes a housing for securing check valve elements adjacent a plate having an inlet and an outlet. The check valve includes a diaphragm positioned to seal or to open fluid communication between a check valve inlet and a check valve outlet. A fluid by-pass is provided for passage of a pressurizing fluid around the check valve into the fluid reservoir.
    Type: Grant
    Filed: December 21, 1990
    Date of Patent: March 17, 1992
    Assignee: Millipore Corporation
    Inventor: Brevard S. Garrison
  • Process for forming printed circuits
    Patent number: 5092967
    Abstract: Printed electrical circuits are formed by coating an electrically insulating substrate with a layer of nickel metal followed by electroplating a second metal layer in a pattern of the desired circuit. Exposed nickel is removed from the substrate by reacting it with carbon monoxide to form nickel carbonyl vapor while the second metal remains unreacted. The nickel carbonyl vapor is heated to form nickel metal and carbon monoxide.
    Type: Grant
    Filed: June 17, 1991
    Date of Patent: March 3, 1992
    Assignee: Romar Technologies Incorporated
    Inventor: Robert G. Guess
  • Vehicle for compacting surfaces
    Patent number: 5088855
    Abstract: A device for compacting surfaces includes a frame and wheels rotatably mounted to the frame. At least one compacting cylinder structure is rotatably mounted to the frame and has an operative position between at least two wheels and the surface to compacted. Structure for driving at least two wheels is provided. The frame is provided in the form of a vehicle whereby the weight of the vehicle and the weight of the driver contribute to compacting the surface. The compacting cylinder comprises disk structures mounted about a central shaft. The disks are secured to an inside surface of a cylindrical sleeve of the compacting cylinder which serves to reduce the inside diameter to a size compatible with a small axle diameter and to provide a cavity to support a bearing assembly. A means for engaging and disengaging the driven wheels and the compacting cylinder is provided.
    Type: Grant
    Filed: May 7, 1990
    Date of Patent: February 18, 1992
    Assignee: Electronic Tug Inernational, Inc.
    Inventor: John Giliberti
  • Porous membrane formed from interpenetrating polymer network having hydrophilic surface
    Patent number: 5079272
    Abstract: A porous membrane is formed from an interpenetrating polymer network of a hydrophobic polymer and a polymerized and crosslinked hydrophilic monomeric composition. A solution of the polymer and monomeric composition is cast, exposed to ultraviolet radiation, coagulated and dried. The resulting dried membrane is annealed in order to render its surface hydrophilic.
    Type: Grant
    Filed: November 30, 1989
    Date of Patent: January 7, 1992
    Assignee: Millipore Corporation
    Inventors: Anthony E. Allegrezza, Jr., Ellen C. Bellantoni
  • Apparatus for measuring oxygen partial pressure and temperature, in living tissue
    Patent number: 5078137
    Abstract: A probe adapted for insertion in living tissue for measuring oxygen partial pressure and temperature at a plurality of sites in living tissue is provided. A temperature sensitive resistor is positioned adjacent each of a plurality of oxygen sensors so that the oxygen partial pressure measured can be adjusted for tissue temperature. The probe substrate has thermal properties similar to living tissue and the resistors are formed of a material having a temperature sensitive resistance. Temperature at each temperature sensitive resistor is obtained by measuring resistance with a four point measurement and correlating the resistance to temperature.
    Type: Grant
    Filed: May 5, 1986
    Date of Patent: January 7, 1992
    Assignee: Massachusetts Institute of Technology
    Inventors: David J. Edell, Stephen K. Burns, Harry F. Bowman, James C. Weaver