Abstract: The present invention provides methods and reagents for targeting probes to selected cellular locations, through the expression of specific binding partners to that probe within the cell. In one embodiment, the probes may comprise spectroscopic probe that can be used in a method for localizing a specific binding partner within a cell, and for creating assays for post-translational activities. The invention allows the monitoring of the location of such intracellular specific binding partners over time and in response to stimuli, such as test chemicals. The spectroscopic probes can be used for screening a test chemical for activity. The present invention also includes cells and transgenic organisms comprising the intracellular specific binding partner, wherein the specific binding partner can bind with the spectroscopic probe/ligand conjugate.

Abstract: A coated steel sheet composed of a steel sheet and at least two types of coating layers formed thereon is provided with an electrodeposition painting having a superior appearance. The coated steel sheet has an arithmetic mean roughness Ra, which is defined by JIS B 0601-1994, of from about 0.7 to about 1.5 ?m and a peak per inch PPI of from about 180 to about 250.

Abstract: A digital camera has an integral flash and a means for storing and displaying a digital image. Under certain conditions, a flash photograph taken with the camera may result in a red-eye phenomenon due to a reflection within an eye of a subject of the photograph. The digital camera has a red-eye filter which analyzes the stored image for the red-eye phenomenon and modifies the stored image to eliminate the red-eye phenomenon by changing the red area to black. The modification of the image is enabled when a photograph is taken under conditions indicative of the red-eye phenomenon. The modification is subject to anti-falsing analysis which further examines the area around the red-eye area for indicia of the eye of the subject.

Abstract: A universal lightweight, easily carried memory identification card records information and controls access to this information. The memory card includes a file system of electronic files on the card, which are automatically detected and recognized by selected authorized readers. The file system is organized so that stored electronic files appear in separate and distinct encrypted compartments in the card, so that only authorized preselected readers have access to particular compartments. Biometric identifying information is imprinted in the card, so that no data can be transferred unless there is a biometric match between a reader and a person assigned to the card and who possesses the card.

Abstract: A measurement module for glucose testing includes a glucose testing measurement module housing, a test strip receptacle formed in the housing, and a connector portion formed in the housing and shaped to permit mechanical removable attachment of the housing to a hand-held computer. Electronics determine the amount of glucose present in a sample of body fluid, when the test strip is positioned in the receptacle and the body fluid is placed on a test strip, and communicate the glucose amount to the hand-held computer via the connector portion.

Abstract: Silicon-oxycarbide optical waveguides and thermooptic devices include a substrate and a first cladding layer having a first refractive index positioned over a substrate. A first core layer comprising silicon, oxygen, and carbon and having a core refractive index is formed on the first cladding layer by chemical vapor deposition using at least two precursors: one inorganic silicon precursor gas and at least one second precursor gas comprising carbon and oxygen. Alternatively, at least three precursors can be used: one inorganic silicon precursor gas, a second precursor comprising carbon, and a third precursor comprising oxygen. The core layer is lithographically patterned to define waveguide elements. A second cladding layer having a second cladding refractive index is formed to surround the optical core waveguiding element of the first core layer.

Abstract: The present invention is based on the discovery of a composition that provides targeted ubiquitination. Specifically the composition contains an ubiquitin pathway protein binding moiety which recognizes an ubiquitin pathway protein and a targeting moiety which recognizes a target protein. In addition, the present invention provides libraries of compositions, where each composition contains an ubiquitin pathway protein binding moiety and a member of a molecular library. The libraries of the present invention can be used to identify proteins involved in a predetermined function of cells.

Abstract: A system and method for early evaluation in micropipeline processors to improve performance is provided. The present invention presents a design methodology where a micropipeline processor block (e.g., a binary full adder) is capable of computing a result based on the arrival of only a subset of inputs. In general, early evaluation allows micropipeline processor blocks to operate in parallel, where they might otherwise operate sequentially because of data arrival dependencies; thereby improving performance of the micropipeline processors.

Abstract: Claspin proteins and nucleotides encoding Claspin proteins are provided. Also provided is a method for identifying a compound that modulates cell cycle progression. A method is further provided for modulating cell cycle progression.

Abstract: An adventure figure system and method are described in which a collectable figurine may be used. Each figurine may have a unique serial number wherein each purchaser of a figurine may create an adventure for the particular figurine using a website. The figurine may then be sent out on its adventure. Each person that comes into contact with the figurine may log into the website and update the figurines location.

Abstract: A system and method for measuring process parameters in a process machine is described. The system is synchronized to the operation of the process machine so that spurious process parameters events are filtered out.

Abstract: An operational amplifier comprises multiple stages. A differential input stage that includes an adaptive high voltage differential pair generates up and down output currents in response to up and down input voltages. The differential input stage includes adaptive common input high voltage (HV) bias. An intermediate stage converts the up and down output currents into a first output voltage signal. The intermediate stage includes a folded cascode arrangement. The intermediate stage is biased by fixed voltage bias signals. The intermediate stage also includes unaffected slew rate stability compensation and a combined split stability compensation. An output stage includes a class AB source follower driver that generates a second output voltage signal in response to the first output voltage signal. The output stage is biased with an adaptive push-pull source follower output HV bias. The output stage includes feed-forward slew rate enhancement.

Abstract: A satellite communications system provides an information channel between remotely located transmitters and receivers. A virtual satellite system provides the same service, but divides the signal either in power or in data content into subchannels such that any particular signal is conducted to the intended receiver via a plurality of traditional satellite channels. The receiving terminal accepts the plurality of signals simultaneously from a possible plurality of satellites, combining the subchannels comprising the virtual channel into the original signal content as if conducted via a single channel. The receiving antenna system receives satellite subchannel signals from a plurality of directions using multiple antennas or a single antenna with multi-direction capability. Prior to signal combining, the receiver necessarily time-synchronizes the plurality of subchannels by introducing time delay in some channels before combining the subsignals into the original composite.

Abstract: A train control system includes a control module that determines a position of a train using a positioning system and consults a database to determine when the train is approaching a portion of track monitored by a track circuit. When the train is near a track circuit, but while the train is still far enough away from the track circuit such that the train can be stopped before reaching the portion of track monitored by the track circuit, the train transmits an interrogation message to a transceiver associated with the track circuit. When the track circuit receives the interrogation message, a test is initiated. The test results are transmitted back to the train. The train takes corrective action if the track circuit fails to respond or indicates a problem.

Abstract: An optical fiber moisture sensor that can be used to sense moisture present in gas phase in a wide range of concentrations is provided, as well techniques for making the same. The present invention includes a method that utilizes the light scattering phenomenon which occurs in a porous sol-gel silica by coating an optical fiber core with such silica. Thus, a porous sol-gel silica polymer coated on an optical fiber core forms the transducer of an optical fiber moisture sensor according to an embodiment. The resulting optical fiber sensor of the present invention can be used in various applications, including to sense moisture content in indoor/outdoor air, soil, concrete, and low/high temperature gas streams.

Abstract: The backlight assembly includes a lamp unit, a light guide plate and a receiving container. The light guide plate includes a light exiting surface, a light reflecting surface facing the light exiting surface, and side surfaces. The receiving container includes a frame plate and sidewall protruding from an outer edge of the frame plate to form a receiving space for receiving the lamp unit and the light guide plate. The first distance between an inner surface of the sidewall and an outer surface of the light guide plate at a first region is greater than a second distance between the inner surface of the sidewall and the outer surface of the light guide plate at a second region. The light guide plate is more spaced apart from the sidewall at the corners where much noise was made, in a general backlight assembly, so that the noise is reduced.

Abstract: A system and method for communicating a package of information. The system comprises a machine readable medium having information packaging software that generates a computer executable file (FIG. 1, 14) comprising a package of information. The packet information comprises the file of data and encryption software. The system communicates the package of information over a network (FIG. 1, 16) that is in communication with a machine readable medium. A client computer system (FIG. 1, 17) in communication with the network is adapted to receive the package of information and execute the computer executable. The computer system has a client permissions database (FIG. 1, 20) and a vault adapted to receive the package of information.

Abstract: A digital multilevel non-volatile memory includes a massive sensing system that includes a plurality of sense amplifiers disposed adjacent subarrays of memory cells. The sense amplifier includes a high speed load, a wide output range intermediate stage and a low impedance output driver. The high speed load provides high speed sensing. The wide output range provides a sensing margin at high speed on the comparison node. The low impedance output driver drives a heavy noisy load of a differential comparator. A precharge circuit coupled to the input and output of the sense amplifier increases the speed of sensing. A differential comparator has an architecture that includes analog bootstrap. A reference sense amplifier has the same architecture as the differential amplifier to reduce errors in offset. The reference differential amplifier also includes a signal multiplexing for detecting the contents of redundant cells and reference cells.