Abstract: A slider window assembly for a motor vehicle includes a fixed panel formed of a single pane encircling an opening formed therein, a slider panel movable along a horizontal axis between closed and open positions, an injection-molded plastic slider frame adhesively bonded to the fixed panel, and at least one seal member forming a seal between the slider frame and the slider panel. The slider frame includes a sealing frame extending entirely about the opening, an upper run located above the opening and receiving the slider panel, and a lower run located below the opening and receiving the slider panel. There is preferably a substantially continuous adhesive bond between the slider frame and the fixed panel that entirely encircles the opening.

Abstract: Absorbent media for gas or heat is provided in a predetermined length of a polygon or curvilinear, and preferably honeycomb (hexagonal) cross sectioned shape with gas absorbent media packed therein. The hexagonal tubes may be installed along the radial or longitudinal axis of a fuel tank. The media and/or media tubes are installed during tank manufacture and include defined physical and gas circulation relationships for maintaining extending tubes having a gas absorbent media therein in a predetermined interrelationship with adjacent spaces (which may be tubes) of similar shape that are either open, or filled with a heat absorbent media.

Abstract: The present invention discloses an immunotherapeutic method for treating a patient suffering from urinary bladder cancer by administering expanded tumour-reactive CD4+ helper and/or CD8+ T-lymphocytes obtainable from one or more sentinel or metinel lymph nodes draining a tumour in the bladder or a metastasis arising from a tumour in the bladder. The method provides a new effective method for treating urinary bladder cancer and metastatic bladder cancer, without adverse side effects associated with the known treatments.

Abstract: The present invention discloses an immunotherapeutic method for treating patients suffering from colon cancer, by administering expanded tumour-reactive CD4+ helper and/or CD8+ T-lymphocytes obtainable from one or more sentinel or metinel lymph nodes draining a tumour in the colon or a metastasis arising from a tumour in the colon. The present invention provides a new effective method for treating colon cancer and metastatic colon cancer, without adverse side effects associated with the known treatments.

Abstract: Methods for treating a patient suffering from a neoplastic disease are disclosed and described. A number of diseases can be treated under the present methods, including without limitation gall bladder cancer, hepato cellular cancer, ovarian cancer, small intestine cancer, lung cancer, mesothelioma, breast cancer, kidney cancer, pancreas cancer, prostate cancer, carcinoid cancer, leiomyosarcoma, or metastasis thereof. A general method for providing such treatment may include: 1) identifying in a patient one or more sentinel and/or metinel lymph nodes draining the neoplasm; 2) resecting the one or more nodes and, optionally all or part of the tumour or metastasis; 3) isolating tumour-reactive T-lymphocytes from said lymph nodes; 4) in vitro expanding said tumour-reactive T-lymphocytes; and 5) administering the thus obtained tumour-reactive T-lymphocytes to the patient.

Abstract: An electronic control system for a transmission includes a transmission controller selectively actuating the transmission between a plurality of gear positions including a reverse position and at least two forward positions, a manually-operable gear shifter selectively providing first command signals to the transmission controller to actuate the transmission between at least a portion of the plurality of gear positions, and a voice recognition system selectively providing second command signals to the transmission controller to actuate the transmission between only a portion of the plurality of gear positions. Preferably, the voice commands actuate the transmission only between the forward gear positions.

Abstract: Ceramic laminate structures, particularly laminate structures including stabilized zirconia compositions, as well as electrodes and electrochemical cells including such laminate structures. The stabilized zirconia composition preferably are selected from scandia-stabilized zirconia and yttria-stabilized zirconia. These laminate structures enhance the overall flexural strength of the electrolyte layer while preserving high electrical conductivity. Such laminate structures may be useful in electrochemical fuel cells such as solid oxide fuel cells.

Abstract: A shift-by-wire shifter system includes a spring biased DTP lever engageable with a shifter lever assembly to move the shifter lever assembly to a park position. A DTP lock assembly secures the DTP lever so that the shifter lever assembly is selectively movable along the shift path during normal operation and releases the DTP lever so that the DTP lever moves the shifter lever assembly to the park position upon the loss of system power. A DTP actuator unlocks the shifter lever assembly and the DPT lock assembly upon the loss of system power so that the DTP lever automatically moves the shifter lever assembly to the park position upon the loss of system power. A power storage device is provided to release power to the DPT actuator upon the loss of system power.

Abstract: The present invention relates to a peptide comprising a symmetrical dimethylated arginine, and constitute an immunologic determinant of antibodies present in sera from patients with systemic lupus erythematosus (SLE), and wherein the methylation is a prerequisite for reacting with said antibodies. The invention also relates to the use of said peptide for diagnosis of SLE and the differentiation between SLE and MCTD.

Abstract: The present invention relates to a method for estimating the risk for development of carcinoma in an individual. More precisely, for estimating the cancer risk in an individual being exposed to human papilloma virus(es) (HPV). The method comprises (i) identification of one or more of said HPV or groups thereof in a sample from said human being; (ii) calculating the amount of HPV of each type or group in the sample and normalising the values to the amount of cells sampled; (iii) estimating the risk for each of the HPV or groups of HPV by comparing each viral titer value from (ii) with type or group specific standard curves for each viral type or group with risk estimation values; and (iv) estimating the combined risk for carcinoma development for the human being from the individual risk estimation curves of the different viral types.

Abstract: A lift and secure latch assembly for a vehicle tailgate includes a pair of cables capable of applying upward force to the tailgate and a tensioning mechanism positioned within the tailgate and connected to the support members to apply tension thereto. One of the cables extends from a first lateral end of the tailgate and the other of the cables extends from a second lateral end of the tailgate. The tensioning mechanism is operable between a first position wherein the cables are retracted with the tailgate closed and a second position wherein the cables are extended with the tailgate open. The tensioning mechanism includes a spring member biasing the tensioning mechanism toward the first position. A latch selectively engages the tensioning mechanism to releasably secure the tensioning mechanism in the first position with the tailgate closed. Preferably, the latch is centrally positioned between lateral ends of the tailgate.

Abstract: A process for producing a poly(arylene sulfide), comprising the respective steps of a washing step of washing a polymer separated from a reaction mixture containing the polymer formed with an organic solvent, which is arranged after a polymerization step, a purification step of purifying the organic solvent recovered after the washing step to lower the content of an alkaline compound mixed therein, and a step of recycling the purified organic solvent through the washing step of the poly(arylene sulfide).

Abstract: A process for producing an aliphatic polyester by subjecting a cyclic ester to ring-opening polymerization, which comprises adding water to a cyclic ester purified to the extent that a water content is at most 60 ppm to control an overall proton concentration in the cyclic ester, thereby controlling at least one physical property among melt viscosity, molecular weight and yellowness index of the resulting aliphatic polyester.

Abstract: An adjustable control pedal includes an upper arm and a lower arm carrying a pedal. The lower arm can be selectively moved relative to the upper arm to adjust the position of the pedal between a forward position and a rearward position. A control pin is operably connected to the upper arm for rotation with the upper arm to supply a control signal when force is applied to the pedal. An adjuster is operably connected to the control pin to adjust the position of the control pin relative to the pivot axis so that a ratio of a distance between the pivot axis and the pedal and a distance between the pivot axis and the control pin remains constant as the pedal is adjusted between the forward position and the rearward position.

Abstract: A window assembly of a motor vehicle includes a pair of spaced-apart fixed window panes forming an opening therebetween, vertically spaced-apart upper and lower tracks, a sliding window pane having opposed upper and lower edges that move along the upper and lower tracks, and a camming mechanism including a plurality of cams. The cams are pivotably secured to the sliding window pane near corners of the sliding window pane. An actuator is operatively connected to the cams for selectively and simultaneously pivoting the cams. Simultaneously pivoting the cams forcibly moves the sliding window pane between a closed position wherein an outside surface of the sliding window pane is in a first plane substantially flush with an outer surface of the fixed window panes and an open position wherein the outside surface of the sliding window pane is in a second plane substantially parallel to and offset from the first plane.

Abstract: A parking brake actuator for a motor vehicle includes a fixed support, a lever pivotably connected to the support for movement between brake-releasing and brake-engaging positions, and a locking mechanism adapted to releasably maintain the lever in the brake-engaging position. An electrical switch has a blade operable to indicate when the lever is out of the brake releasing position. The fixed support forms a unitary mounting bracket for securing the switch blade to the fixed support so that the switch is integrated with the actuator. The fixed support and the unitary mounting bracket are preferably unitarily molded of plastic. The switch is preferably located near a mounting hole formed in the fixed support which receives a fastener to secure the fixed support to the motor vehicle. The switch can then extend to the mounting hole to contact the fastener and connect the switch to motor vehicle ground.

Abstract: The invention relates to a hypoallergenic immunogenic molecule derived from the Phl p 6 allergen, wherein the Phl p6 molecule has an N-terminal and/or C-terminal deletion which makes the molecule at least substantially lack IgE binding capacity. The invention also relates to a hypoallergenic immunogenic combination of molecules derived from the Phl p 6 allergen, comprising (i) a Phl p 6 molecule having an N-terminal deletion which makes the molecule at least substantially lack IgE binding capacity, and (ii) a Phl p 6 molecule having a C-terminal deletion which makes the molecule at least substantially lack IgE binding capacity, which two molecules together encompass the complete sequence of Phl p 6. The invention further relates to the use of the hypoallergenic immunogenic molecule or molecule mixture in hyposensitization and diagnosis.

Abstract: The invention relates to a hypoallergenic immunogenic molecule derived from the Phl p 6 allergen, wherein the Phl p 6 molecule has an N-terminal and/or C-terminal deletion which makes the molecule at least substantially lack IgE binding capacity. The invention also relates to a hypoallergenic immunogenic combination of molecules derived from the Phl p 6 allergen, comprising (i) a Phl p 6 molecule having an N-terminal deletion which makes the molecule at least substantially lack IgE binding capacity, and (ii) a Phl p 6 molecule having a C-terminal deletion which makes the molecule at least substantially lack IgE binding capacity, which two molecules together encompass the complete sequence of Phl p 6. The invention further relates to the use of the hypoallergenic immunogenic molecule or molecule mixture in hyposensitization and diagnosis.