Abstract: Methods are provided for ascertaining the sequence of a genomic DNA sample by nicking the DNA sample with a restriction nicking enzyme, followed by nick translation with labeled nucleotides, such that the labeled nucleotides can be quantified and compared to a known, reference genome.

Abstract: A method for reconstructing a high quality image from undersampled image data is provided. The image reconstruction method is applicable to a number of different imaging modalities. Specifically, the present invention provides an image reconstruction method that incorporates an appropriate prior image into an iterative image reconstruction process as well as utilizing an image frame from a previous time frame to constrain the reconstruction of a current image frame.

Abstract: A method and kit for determining a concentration of iron in brake fluid when contacting a colorimetric reagent such that a color results. The level of iron can be used to determine the amount of active corrosion within a brake system and determine if special service procedures are required.

Abstract: The invention provides a cyclometallated complex comprising the structure of formula I wherein: M is a d-block transition metal; B is a five- or six-membered aryl or heteroaryl ring which is optionally substituted and optionally fused to one or more other aryl or heteroaryl rings; A is a five- or six-membered heteroaryl ring comprising at least three nitrogen atoms; R1 is a group other than hydrogen; n is zero or an integer equal to or greater than one; and A and B are optionally fused or linked by one or more covalent bonds. The invention also provides the use of such complexes in optoelectronic devices, and in particular in organic light emitting devices.

Abstract: An atomic clock comprises endohedral fullerene systems which provide the standard frequency oscillations. A magnet device applies a magnetic field to the endohedral fullerenes. The applied magnetic field is adjustable. An excitation device both excites each endohedral fullerene system to cause it to undergo transitions which generate the time-keeping oscillations, and also probes the systems such that the oscillations can be measured and the device controlled. A detection device senses the response of the systems induced by the excitation device. The output of the detection device is fed to a controller. The controller produces the atomic clock output, which is the clock signal or frequency standard, and also controls the magnet device and the excitation device.

Abstract: A system and method for performing a welding-type process includes a welding-type torch having a first electrode connected to receive a welding-type power to effectuate a welding-type process. The welding-type torch also includes a second electrode connected to receive a starting power to initiate the welding-type process and a nozzle surrounding at least a portion of the first electrode.

Abstract: A pathogen-resistant fabric comprising one or more photocatalysts capable of generating singlet oxygen from ambient air. The pathogen-resistant fabric may optionally include one or more singlet oxygen traps.

Abstract: A valve assembly couples a plurality of hydraulic actuators to a variable displacement pump and to a tank. A separate valve is associated with each hydraulic actuator and comprises a variable flow source orifice between the supply conduit and a summation node coupled to a pump control port, a variable metering orifice between the summation node and the associated hydraulic actuator, and a variable bypass orifice between the summation node and the tank. As a valve operates to enlarge the metering orifice, the flow source orifice also enlarges, and the bypass orifice shrinks. When the valve operates to shrink the metering orifice, the flow source orifice also shrinks and the bypass orifice enlarges. Those operations vary fluid flow in and out of the summation node, which alters pressure applied to the pump control, thereby causing the pump output to vary as required to drive the associated hydraulic actuator.

Abstract: A particle detector has a sample area of cross section no in excess of about 2 mm for containing environmental fluid, a light source on one side of the sample area for directing a collimated or nearly collimated beam of light through the sample air or water so that part of the light beam will be scattered by any particles present in the air or water while the remainder remains unscattered, and a beam diverting device on the opposite side of the sample area for diverting or blocking at least the unscattered portion of the beam of light and directing at least part of the scattered light onto a detector. The detector produces output pulses in which each pulse has a height proportional to particle size and a pulse height discriminator obtains the size distribution of airborne particles detected in the air or water sample at a given time from the detector output. The detector may also include a device for discriminating between biological agents and inorganic particles.

Abstract: A method for accessing data in a data storage system is presented. The method includes supplying a host computer that is in communication with the data storage system, where the data storage system includes a data storage medium and a holographic data storage medium. A first request is generated to access a directory encoded in the data storage medium and includes a first encryption key. The requested directory recites a listing of data files encoded in the holographic storage medium. If the first encryption key decrypts the directory, the directory is read and a data file encoded in the holographic data storage medium is identified. A second request is then generated to access the data file and includes a second encryption key. Finally, if the second encryption key decrypts the data file, then it is read.

Abstract: A method for prescribing a scan on an MRI system includes selecting a general pulse sequence to be used during a time-resolved imaging process of a subject using an MRI system. The method also includes setting a first set of scan parameters to more specifically prescribe the general pulse sequence and setting a second set of scan parameters using a formula that relates time resolution and spatial resolution resulting from the first set of scan parameters. The method then includes performing the time-resolved imaging process using the general pulse sequence, the first set of scan parameters, and the second set of scan parameters.

Abstract: A method of and system for operating a captioned telephone service, the method comprising the steps of providing words spoken by a remote user to a relay, at the relay, a call assistant listening to the words spoken by the remote user and re-voicing the words into a computer with voice recognition software trained to the voice of the call assistant to create a text stream of the words spoken by the remote user and presenting the text stream to an assisted user via a display.

Abstract: A population of iPS cells derived from somatic cells from a spinal muscular atrophy patient is disclosed. In one embodiment of the invention, the cells have been cultured to produce neural cells. In another embodiment, the invention is a method of testing compounds for their ability to modify cellular SMN levels comprising the steps of obtaining a population of iPS cells derived from a spinal muscular atrophy patient or cells derived from the iPS cells, and examining the effect of a test compound on SMN levels.

Abstract: The invention provides a rapid, quantitative assay to directly assess the impact of a diverse range of sugars upon the sugar-mediated uptake of corresponding sugar-conjugates into various cell types.

Abstract: The present invention provides a PM main bearing cap, and its precursor compact, with an undercut breathing window that is formed during a compaction process. By fabricating the undercut during the compaction process, the invention eliminates the need for a secondary machining operation to form the undercut feature in the bearing caps.