Patents Represented by Attorney Quine Intellectual Property Law Group, P.C.

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  • Chimeric promoters
    Patent number: 7074590
    Abstract: This invention provides novel chimeric promoter/enhancers. The chimeric promoter/enhancers are particularly suitable for directing gene expression in mammalian cells.
    Type: Grant
    Filed: June 21, 2001
    Date of Patent: July 11, 2006
    Assignee: Maxygen, Inc.
    Inventors: Juha Punnonen, Anne Wright, Andrey Semyonov
  • Structures, systems and methods for joining articles and materials and uses therefor
    Patent number: 7074294
    Abstract: This invention provides novel nanofibers and nanofiber structures which posses adherent properties, as well as the use of such nanofibers and nanofiber comprising structures in the coupling and/or joining together of articles or materials.
    Type: Grant
    Filed: April 19, 2004
    Date of Patent: July 11, 2006
    Assignee: Nanosys, Inc.
    Inventor: Robert Dubrow
  • Methods, devices and compositions for depositing and orienting nanostructures
    Patent number: 7067328
    Abstract: Methods and systems for depositing nanomaterials onto a receiving substrate and optionally for depositing those materials in a desired orientation, that comprise providing nanomaterials on a transfer substrate and contacting the nanomaterials with an adherent material disposed upon a surface or portions of a surface of a receiving substrate. Orientation is optionally provided by moving the transfer and receiving substrates relative to each other during the transfer process.
    Type: Grant
    Filed: September 25, 2003
    Date of Patent: June 27, 2006
    Assignee: Nanosys, Inc.
    Inventors: Robert Dubrow, Linda T. Romano, David Stumbo
  • Nanocomposites
    Patent number: 7068898
    Abstract: This invention provides composite materials comprising nanostructures (e.g., nanowires, branched nanowires, nanotetrapods, nanocrystals, and nanoparticles). Methods and compositions for making such nanocomposites are also provided, as are articles comprising such composites. Waveguides and light concentrators comprising nanostructures (not necessarily as part of a nanocomposite) are additional features of the invention.
    Type: Grant
    Filed: September 4, 2003
    Date of Patent: June 27, 2006
    Assignee: Nanosys, Inc.
    Inventors: Mihai Buretea, Stephen Empedocles, Chunming Niu, Erik C. Scher
  • Structures, systems and methods for joining articles and materials and uses therefor
    Patent number: 7056409
    Abstract: This invention provides novel nanofibers and nanofiber structures which posses adherent properties, as well as the use of such nanofibers and nanofiber comprising structures in the coupling and/or joining together of articles or materials.
    Type: Grant
    Filed: September 12, 2003
    Date of Patent: June 6, 2006
    Assignee: Nanosys, Inc.
    Inventor: Robert Dubrow
  • Rolling circle replicon expression vector
    Patent number: 7049134
    Abstract: A rolling circle DNA replicon which replicates in a host eukaryotic cell is disclosed which has a truncated replication cycle. The rolling circle DNA replicon comprises the following elements present on the same DNA molecule. It contains a Rep gene open reading frame from a virus belonging to the viral taxonomic families Geminiviridae, Circoviridae or genus Nanovirus. The Rep gene open reading frame is placed under transcriptional control of a promoter, which is placed 5? of the gene. Any sequences that are required to be present in cis on the rolling circle DNA replicon in order that the Rep protein might promote replication of the rolling circle DNA replicon are included. An expression cassette for expression of an ancillary protein that is capable of creating a cellular environment permissive for replication of the rolling circle DNA replicon in the host cell of interest is also included.
    Type: Grant
    Filed: November 1, 2002
    Date of Patent: May 23, 2006
    Assignee: Large Scale Biology Corporation
    Inventors: Kenneth E. Palmer, Gregory P. Pogue
  • Methods of high-throughput screening for internalizing antibodies
    Patent number: 7045283
    Abstract: This invention provides methods of identifying ligands that are internalized into a cell. The methods typically involve i) contacting the cell with a reporter non-covalently coupled to a ligand; ii) dissociating the reporter from the ligand and removing dissociated reporter from the surface of the cell; and iii) detecting the reporter within said cell (if any is present) where the presence of the reporter within said cell indicates that the ligand binds to an internalizing receptor and is internalized.
    Type: Grant
    Filed: October 16, 2001
    Date of Patent: May 16, 2006
    Assignee: The Regents of the University of California
    Inventors: James D. Marks, Ulrik B. Nielson, Dimitri B. Kirpotin
  • In vivo incorporation of unnatural amino acids
    Patent number: 7045337
    Abstract: The invention provides methods and compositions for in vivo incorporation of unnatural amino acids. Also provided are compositions including proteins with unnatural amino acids.
    Type: Grant
    Filed: April 19, 2002
    Date of Patent: May 16, 2006
    Assignees: The Scripps Research Institute, The Regents of the University of California
    Inventors: Peter Schultz, Lei Wang, John Christopher Anderson, Jason William Chin, David R. Liu, Thomas J. Magliery, Eric L. Meggers, Ryan A. Mehl, Miro Pastrnak, Steven William Santoro, Zhiwen Zhang
  • Methods and devices for analysis of sealed containers
    Patent number: 7012427
    Abstract: This invention provides methods, NMR probes, and NMR systems for the analysis of the contents of sealed food and beverage containers and the like.
    Type: Grant
    Filed: December 16, 2004
    Date of Patent: March 14, 2006
    Assignee: The Regents of the University of California
    Inventors: Matthew P. Augustine, April J. Weekley, Paul Bruins
  • Technician safety confirmation
    Patent number: 6994258
    Abstract: The present invention provides safety confirmation or hazard warning to a technician in the field, e.g., by scanning an equipment identification label and comparing the identification to a schedule of equipment inactivation times. The systems and methods of the invention can optionally provide remote interactions to reschedule inactivations or to protect the technician by lock-out from a hazardous condition.
    Type: Grant
    Filed: August 2, 2002
    Date of Patent: February 7, 2006
    Inventor: Richard Jeffrey Lewis
  • Stackable dollies and dolly systems
    Patent number: 6979005
    Abstract: Stackable dollies that each include a platform component having a plurality of indentations that is structured to receive wheel components of other dollies are provided. Stackable dolly systems and related methods are also provided.
    Type: Grant
    Filed: June 16, 2003
    Date of Patent: December 27, 2005
    Assignee: Chriscott Supply, Inc.
    Inventor: Steve McLerran
  • Retrieval catheter
    Patent number: 6966914
    Abstract: This invention provides, e.g., a catheter with a threaded loop type snare tool for retrieval of objects from blood vessels and/or body cavities. The snare tool of the invention provides, e.g., independently maneuverable probe wires and snare wires to encircle and releasably snare foreign objects inside human and veterinary patients. The invention further provides methods of using the catheter of the invention to retrieve objects from patients.
    Type: Grant
    Filed: May 16, 2002
    Date of Patent: November 22, 2005
    Assignee: The Regents of the University of California
    Inventor: Bennett K. Abe
  • Method and apparatus for performing multiple processing steps on a sample in a single vessel
    Patent number: 6964867
    Abstract: A method is provided for determining crystallization conditions for a protein, the method comprising: performing in a same fermentation apparatus 2 or more separate fermentations where each fermentation comprises cells expressing a protein to be purified and has a fermentation volume of less than 500 mL; purifying the expressed protein from the separate fermentations; and determining crystallization conditions for the purified protein by submicroliter crystallization experiments.
    Type: Grant
    Filed: March 18, 2002
    Date of Patent: November 15, 2005
    Assignee: IRM, LLC
    Inventor: Robert Charles Downs
  • Chemokines and methods for inducing the differentiation of fibroblasts to myofibroblasts
    Patent number: 6962971
    Abstract: This invention is based on the discovery that chemokines induce fibroblasts to differentiate to myofibroblasts, which play a critical role in wound healing and are implicated in a number of fibrotic diseases. This activity has been localized to a peptide in the N-terminus of several chemokines. Accordingly, the invention provides polypeptides that induce the differentiation of fibroblasts to myofibroblasts in vitro and in vivo, nucleic acids encoding such polypeptides and related vectors, host cells, and composition containing these components. The invention also encompasses methods for inducing or inhibiting differentiation of fibroblasts to myofibroblasts, in vivo as well as in vitro, and screening methods for identifying other agents that modulate myofibroblast differentiation.
    Type: Grant
    Filed: March 16, 2001
    Date of Patent: November 8, 2005
    Assignee: The Regents of the University of California
    Inventors: Manuela Martins-Green, Jo Ellen Feugate, QiJing Li
  • Methods of making, positioning and orienting nanostructures, nanostructure arrays and nanostructure devices
    Patent number: 6962823
    Abstract: Nanostructure manufacturing methods and methods for assembling nanostructures into functional elements such as junctions, arrays and devices are provided. Systems for practicing the methods are also provided.
    Type: Grant
    Filed: April 1, 2003
    Date of Patent: November 8, 2005
    Assignee: Nanosys, Inc.
    Inventors: Stephen Empedocles, Larry Bock, Calvin Chow, Xianfeng Duan, Chungming Niu, George Pontis, Vijendra Sahi, Linda T. Romano, David Stumbo
  • Methods and systems for data analysis
    Patent number: 6954722
    Abstract: The present invention provides methods of analyzing and/or displaying data. In one aspect, the invention provides methods for visualizing or displaying high dynamic range data obtained from flow cytometry analyses. Related systems and computer programs products are also provided.
    Type: Grant
    Filed: October 17, 2003
    Date of Patent: October 11, 2005
    Assignee: Leland Stanford Junior University
    Inventors: David R. Parks, Wayne A. Moore
  • Gripping mechanisms, apparatus, and methods
    Patent number: 6932557
    Abstract: The present invention provides grasping mechanisms, gripper apparatus/systems, and related methods. Grasping mechanisms that include stops, support surfaces, and height adjusting surfaces to determine three translational axis positions of a grasped object are provided. In addition, grasping mechanisms that are resiliently coupled to other gripper apparatus components are also provided.
    Type: Grant
    Filed: July 14, 2003
    Date of Patent: August 23, 2005
    Assignee: IRM, LLC
    Inventors: Robert Charles Downs, Mark Richard Weselak, James Kevin Mainquist
  • Orally administered peptides to ameliorate atherosclerosis
    Patent number: 6933279
    Abstract: This invention provides novel peptides that ameliorate one or more symptoms of atherosclerosis. The peptides are highly stable and readily administered via an oral route.
    Type: Grant
    Filed: June 29, 2001
    Date of Patent: August 23, 2005
    Assignee: The Regents of the University of California
    Inventors: Alan M. Fogelman, Gattadahalli M. Anantharamaiah, Mohamad Navab
  • Striking head-interchangeable hammer with a stress-distributable fastener
    Patent number: 6928899
    Abstract: A striking head-interchangeable hammer includes a handle, a head body connected securely to the handle and formed with a through-hole and upper and lower bores, a striking body having a connecting portion that is received fittingly in the lower bore, and a stress-distributable fastener including a connecting rod that extends through the through-hole and the upper and lower bores in the head body to engage threadedly the striking body, and that is formed with an abutting flange received fittingly in the upper bore and anchored on and abutting against an abutting face of a bore-defining wall of the upper bore upon tightening of the connecting rod onto the striking body.
    Type: Grant
    Filed: May 12, 2004
    Date of Patent: August 16, 2005
    Inventor: Ming-Hsuan Lin
  • Wine funnel
    Patent number: D514901
    Type: Grant
    Filed: June 29, 2004
    Date of Patent: February 14, 2006
    Assignee: Well Join Industry Co. Ltd.
    Inventor: Cherry Wang