Patents Represented by Attorney Quine Intellectual Property Law Group, P.C.

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  • Methods and composition for the production of orthogonal tRNA-aminoacyltRNA synthetase pairs
    Patent number: 7354761
    Abstract: This invention provides compositions and methods for generating components of protein biosynthetic machinery including orthogonal tRNAs, orthogonal aminoacyl-tRNA synthetases, and orthogonal pairs of tRNAs/synthetases. Methods for identifying orthogonal pairs are also provided. These components can be used to incorporate unnatural amino acids into proteins in vivo.
    Type: Grant
    Filed: October 18, 2005
    Date of Patent: April 8, 2008
    Assignees: The Scripps Research Institute, The Regents of the University of California
    Inventors: Peter G. Schultz, Lei Wang, John Christopher Anderson, Jason Chin, David R. Liu, Thomas J. Magliery, Eric L. Meggers, Ryan Aaron Mehl, Miro Pastrnak, Steven William Santoro, Zhiwen Zhang
  • Low platinum fuel cell catalysts and method for preparing the same
    Patent number: 7351444
    Abstract: This invention provides novel fuel cell catalysts comprising new series of catalytically active thin-film metal alloys with low platinum concentration supported on nanostructured materials (nanoparticles). In certain embodiments, an integrated gas-diffusion/electrode/catalyst layer can be prepared by processing catalyst thin films and nanoparticales into gas-diffusion media such as Toray or SGL carbon fiber papers. The catalysts can be placed in contact with an electrolyte membrane for PEM fuel cell applications.
    Type: Grant
    Filed: April 12, 2004
    Date of Patent: April 1, 2008
    Assignee: Intematix Corporation
    Inventors: Ning Wang, Yi Dong, Yi-Qun Li
  • HIV capsid assembly-associated compositions and method
    Patent number: 7348134
    Abstract: A cell-free method for translation and assembly of retroviral, particularly HIV, capsid and capsid intermediates is disclosed. Also disclosed are novel HIV capsid assembly intermediates and novel host proteins which bind to such assembly intermediates. The invention also includes a screening method for compounds that alter retrovirus capsid assembly, and a method of treating HIV using compounds which inhibit the HIV capsid assembly pathway.
    Type: Grant
    Filed: January 17, 2003
    Date of Patent: March 25, 2008
    Assignee: The Regents of the University of California
    Inventors: Jaisri R. Lingappa, Vishwanath R. Lingappa
  • Methods and devices for analysis of sealed containers
    Patent number: 7339377
    Abstract: This invention provides methods, NMR probes, and NMR systems for the analysis of the contents of sealed food and beverage containers and the like.
    Type: Grant
    Filed: March 10, 2006
    Date of Patent: March 4, 2008
    Assignee: The Regents of the University of California
    Inventors: Matthew P. Augustine, April J. Weekley, Paul Bruins
  • Bicycle derailer generator
    Patent number: 7321218
    Abstract: A derailler with a set of gears powered by bicycle chain to drive an AC generator. A bridge rectifier to convert AC to DC to charge the battery and to energize the head light and the tail light. A set of switches to control the head light, tail light, and battery.
    Type: Grant
    Filed: May 19, 2003
    Date of Patent: January 22, 2008
    Inventor: Powell D. Nyachoto
  • Monitoring heart failure
    Patent number: 7319017
    Abstract: An in vitro method for identifying subjects at risk of heart failure following a Myocardial Infarction comprising analyzing the concentration of Matrix Metalloproteinase-9 in a bodily sample from a subject who has suffered a Myocardial Infarction and comparing this concentration with a reference for concentrations of Matrix Metalloproteinase-9 in individuals who have not suffered a Myocardial Infarction; wherein a raised concentration of Matrix Metalloproteinase-9 in the bodily sample from a subject who has suffered a Myocardial Infarction suggests the subject is at risk of heart failure.
    Type: Grant
    Filed: July 13, 2005
    Date of Patent: January 15, 2008
    Assignee: Centre de Recherche Public de la Santé
    Inventor: Daniel R. Wagner
  • Nano-chem-FET based biosensors
    Patent number: 7303875
    Abstract: Methods of detecting components of interest, e.g., nucleic acids and sugars, are provided. The methods comprise contacting one or more nanowires comprising a functional group with a sample containing the component or components of interest. In one embodiment, the functional group comprises a hairpin oligonucleotide, e.g., a hairpin that changes conformation upon binding the component of interest, e.g., a nucleic acid. The change in conformation produces a change in charge that is detected. In another embodiment, the functional group comprises an enzyme, e.g., glucose oxidase, which produces a change in pH when glucose is present in a sample.
    Type: Grant
    Filed: October 9, 2003
    Date of Patent: December 4, 2007
    Assignee: Nanosys, Inc.
    Inventors: Larry Bock, R. Hugh Daniels, Stephen Empedocles
  • Method and apparatus providing deception and/or altered execution of logic in an information system
    Patent number: 7296274
    Abstract: A method and/or system and/or apparatus providing deception and/or execution alteration in an information system. In specific embodiments, deceptions and/or protections are provided by intercepting and/or modifying operation of one or more system calls of an operating system.
    Type: Grant
    Filed: October 3, 2003
    Date of Patent: November 13, 2007
    Assignee: Sandia National Laboratories
    Inventors: Fred Cohen, Deanna T. Rogers, Vicentiu Neagoe
  • Data stream permutation applicable to large dimensions
    Patent number: 7283520
    Abstract: Multi-stage networks are used for data stream permutations involving merging and demultiplexing—providing arbitrary data unit time-space interchange that can be used to solve a range of problems particularly in the field of digital data communications, particularly in digital data communication involving advanced networks for exchanging data in packets, cells, or other data units.
    Type: Grant
    Filed: April 19, 2002
    Date of Patent: October 16, 2007
    Assignee: PMC-Sierra, Inc.
    Inventors: Heng Liao, Xiaofeng Wang, Zhao Wu
  • Doped cadmium tungstate scintillator with improved radiation hardness
    Patent number: 7279120
    Abstract: This invention provides novel cadmium tungstate scintillator materials that show improved radiation hardness. In particular, it was discovered that doping of cadmium tungstate (CdWO4) with trivalent metal ions or monovalent metal ions is particularly effective in improving radiation hardness of the scintillator material.
    Type: Grant
    Filed: August 27, 2004
    Date of Patent: October 9, 2007
    Assignee: Intematix Corporation
    Inventors: Shifan Cheng, Yi-Qun Li
  • Uncaging device
    Patent number: 7271886
    Abstract: Uncaging devices that can be used to uncage photoactivatable caged components are provided. Consistent, uniform and/or high throughput processing of reactions and assays that include caged components is provided. Masked multiwell plates that can be used for uncaging photoactivatable caged components are provided. Methods and apparatus for initiating assays involving caged components are provided.
    Type: Grant
    Filed: November 17, 2003
    Date of Patent: September 18, 2007
    Assignee: Panomics, Inc.
    Inventors: Frank Witney, Gary McMaster, Quan Nguyen, Steve Chen
  • Post-deposition encapsulation of nanostructures: compositions, devices and systems incorporating same
    Patent number: 7267875
    Abstract: Ligand compositions for use in preparing discrete coated nanostructures are provided, as well as the coated nanostructures themselves and devices incorporating same. Methods for post-deposition shell formation on a nanostructure and for reversibly modifying nanostructures are also provided. The ligands and coated nanostructures of the present invention are particularly useful for close packed nanostructure compositions, which can have improved quantum confinement and/or reduced cross-talk between nanostructures.
    Type: Grant
    Filed: June 7, 2005
    Date of Patent: September 11, 2007
    Assignee: Nanosys, Inc.
    Inventors: Jeffery A. Whiteford, Mihai Buretea, William P. Freeman, Andreas Meisel, Kyu S. Min, J. Wallace Parce, Erik Scher
  • Glycoprotein synthesis
    Patent number: 7262040
    Abstract: Methods for making glycoproteins, both in vitro and in vivo, are provided. One method involves incorporating an unnatural amino acid into a protein and attaching one or more saccharide moieties to the unnatural amino acid. Another method involves incorporating an unnatural amino acid that includes a saccharide moiety into a protein. Proteins made by both methods can be further modified with additional sugars.
    Type: Grant
    Filed: March 29, 2005
    Date of Patent: August 28, 2007
    Assignee: The Scripps Research Institute
    Inventors: Peter G. Schultz, Lei Wang, Zhiwen Zhang
  • Preservation of bioactive materials by spray drying
    Patent number: 7258873
    Abstract: This invention provides methods and compositions to preserve bioactive materials in a matrix of powder particles. Methods provide high-pressure gas spraying and/or near supercritical spraying of formulations followed by drying in a stream of conditioned gas to form stable powder particles containing bioactive materials.
    Type: Grant
    Filed: April 10, 2003
    Date of Patent: August 21, 2007
    Assignee: MedImmune Vaccines, Inc.
    Inventors: Vu Truong-Le, Binh Pham
  • Ferroelectric rare-earth manganese-titanium oxides
    Patent number: 7250648
    Abstract: Ferroelectric rare-earth manganese-titanium oxides and methods of their manufacture. The ferroelectric materials can provide nonvolatile data storage in rapid access memory devices.
    Type: Grant
    Filed: September 3, 2004
    Date of Patent: July 31, 2007
    Assignee: Intematix Corporation
    Inventors: Yi-Qun Li, Young Yoo, Qizhen Xue, Ning Wang, Daesig Kim
  • QTL controlling stem rot resistance in soybean
    Patent number: 7250552
    Abstract: Markers associated with Sclerotinia stem rot resistance are provided. Methods of identifying resistant, and susceptible plants, using the markers are provided. Methods for identifying and isolating QTL are a feature of the invention, as are QTL associated with Sclerotinia stem rot resistance.
    Type: Grant
    Filed: June 7, 2002
    Date of Patent: July 31, 2007
    Assignee: Pioneer Hi-Bred International, Inc.
    Inventors: Feng Han, Maria Katt, Wolfgang Schuh, David M. Webb
  • Internalizing ERB2 antibodies
    Patent number: 7244826
    Abstract: This invention provides novel erbB2-binding internalizing antibodies. The antibodies, designated F5 and C1, specifically bind to c-erbB2 antigen and, upon binding, are readily internalized into the cell bearing the c-erbB2 marker. Chimeric molecules comprising the F5 and/or C1 antibodies attached to one or more effector molecules are also provided.
    Type: Grant
    Filed: February 12, 1999
    Date of Patent: July 17, 2007
    Assignee: The Regents of the University of California
    Inventors: James D. Marks, Marie Alix Poul
  • Glycoprotein synthesis
    Patent number: 7238510
    Abstract: Methods for making glycoproteins, both in vitro and in vivo, are provided. One method involves incorporating an unnatural amino acid into a protein and attaching one or more saccharide moieties to the unnatural amino acid. Another method involves incorporating an unnatural amino acid that includes a saccharide moiety into a protein. Proteins made by both methods can be further modified with additional sugars.
    Type: Grant
    Filed: December 14, 2004
    Date of Patent: July 3, 2007
    Assignee: The Scripps Research Institute
    Inventors: Peter G. Schultz, Lei Wang, Zhiwen Zhang
  • Engineering single-gene-controlled staygreen potential into plants utilizing ACC synthase from maize
    Patent number: 7230161
    Abstract: The enzymes of the ACC synthase family are used in producing ethylene. Nucleotide and polypeptide sequences of ACC synthases are provided along with knockout plant cells having inhibition in expression and/or activity in an ACC synthase and knockout plants displaying a staygreen phenotype, a male sterility phenotype, or an inhibition in ethylene production. Methods for modulating staygreen potential in plants, methods for modulating sterility in plants, and methods for inhibiting ethylene production in plants are also provided.
    Type: Grant
    Filed: June 22, 2004
    Date of Patent: June 12, 2007
    Assignees: Pioneer Hi-Bred International, Inc., The Regents of the University of California
    Inventors: Daniel R. Gallie, Robert Meeley, Todd Young
  • Nanocomposites
    Patent number: 7228050
    Abstract: This invention provides composite materials comprising nanostructures (e.g., nanowires, branched nanowires, nanotetrapods, nanocrystals, and nanoparticles). Methods and compositions for making such nanocomposites are also provided, as are articles comprising such composites. Waveguides and light concentrators comprising nanostructures (not necessarily as part of a nanocomposite) are additional features of the invention.
    Type: Grant
    Filed: January 26, 2006
    Date of Patent: June 5, 2007
    Assignee: Nanosys, Inc.
    Inventors: Mihai Buretea, Stephen Empedocles, Chunming Niu, Erik C. Scher