Patents Represented by Law Firm Sherman and Shalloway
  • Patent number: 5942545
    Abstract: A composition for the topical transdermal administration to the penis is based on prostaglandin E.sub.1. The composition is non-irritating and effective for relieving erectile impotence or other penile erectile dysfunction. A penetration enhancing effective amount of a dioxolane, dioxane, or acetal skin penetration enhancing compound in a pharmaceutically acceptable aqueous alcoholic carrier is used to facilitate the penetration of the prostaglandin E.sub.1 active ingredient through the skin. Phentolamine or prazosin may be used in combination with prostaglandin E.sub.1.
    Type: Grant
    Filed: May 27, 1997
    Date of Patent: August 24, 1999
    Assignee: MacroChem Corporation
    Inventors: Carlos M. Samour, Scott F. Krauser, Robert J. Gyurik
  • Patent number: 5939586
    Abstract: A process for the production of an intermediate for a liquid crystal compound, which comprises reacting an alkyloxybiphenylcarboxylic acid with purified thionyl chloride substantially free of sulfuryl chloride, the thionyl chloride being obtained by adding phenol, etc., to thionyl chloride, heating the mixture and distilling the resultant mixture; and a process for the production of a liquid crystal compound from the above intermediate. According to the present invention, thionyl chloride can be easily purified, and a liquid crystal compound having a very high purity can be obtained by the use of the purified thionyl chloride.
    Type: Grant
    Filed: October 31, 1997
    Date of Patent: August 17, 1999
    Assignee: Mitsubishi Gas Chemical Company, Inc.
    Inventors: Hiroshi Mineta, Tomoyuki Yui
  • Patent number: 5938973
    Abstract: A swallow-tailed compound of the following general formula (1), ##STR1## wherein m is an integer of 4 to 10, n is an integer of 2 to 6, p is 0 or 1 and each of X and Y is independently a hydrogen or fluorine atom; and a ferrielectric liquid crystal composition consisting essentially of the swallow-tailed compound of the general formula (1) and a ferrielectric liquid crystal compound of the following general formula (2), ##STR2## wherein R is a linear alkyl group having 6 to 12 carbon atoms, Z is a hydrogen or fluorine atom, r is an integer of 2 to 4 and s is an integer of 2 to 4. The ferrielectric liquid crystal composition has a ferrielectric phase in a broad temperature range and attains a fast response and a large tilt angle in a broad temperature range so that a ferrielectric liquid crystal display device having high display qualities can be provided.
    Type: Grant
    Filed: September 11, 1997
    Date of Patent: August 17, 1999
    Assignee: Mitsubishi Gas Chemical Company
    Inventors: Yuki Motoyama, Tomoyuki Yui, Masahiro Johno, Takahiro Matsumoto
  • Patent number: 5939345
    Abstract: A high-performance prepolymerized solid catalyst is prepared by polymerizing an olefin onto an olefin polymerization catalyst in a heterogeneous system under irradiation with an elastic wave, wherein the olefin is prepolymerized in an amount of not less than 0.1 g based on 1 mmol of a transition metal contained in the olefin polymerization catalyst. The elastic wave is preferably an ultrasonic wave.
    Type: Grant
    Filed: August 26, 1997
    Date of Patent: August 17, 1999
    Assignee: Mitsui Chemicals, Inc.
    Inventors: Atsuo Kobata, Tetsuhiro Matsumoto
  • Patent number: 5939495
    Abstract: The present invention relates to a process for producing a polyolefin having a functional group at its terminal and the object thereof is to provide a process in which the above polyolefin can be obtained with industrial advantages. This object can be attained by the process comprising step (A) producing a terminal-modified polyolefin of the formula P-AlR.sup.1 R.sup.2, wherein P is a polymer chain and each of R.sup.1 and R.sup.2 is, for example, a hydrocarbon group having 1 to 10 carbon atoms, in the presence of an olefin polymerization catalyst composed of a solid titanium catalyst component (a) and an organoaluminum compound catalyst component (b) optionally together with an organosilicon compound (c) and step (B) producing a polyoiefin of the formula P-X, wherein P is as defined above and X is a functional group, by conducting a substitution reaction between -AlR.sup.1 R.sup.
    Type: Grant
    Filed: April 10, 1997
    Date of Patent: August 17, 1999
    Assignee: Mitsui Chemicals, Inc.
    Inventors: Mamoru Kioka, Shinichi Kojo
  • Patent number: 5936053
    Abstract: A propylene polymer is excellent in rigidity, heat resistance, surface hardness, glossiness, transparency and impact resistance. A propylene copolymer (wherein the amount of monomer units derived from an .alpha.-olefin other than propylene is not more than 5% by mol) is excellent in transparency, rigidity, surface hardness, heat resistance, heat-sealing property, anti-blocking property, anti-bleedout property and impact strength. A propylene copolymer (wherein the amount of monomer units derived from an .alpha.-olefin other than propylene is not less than 5% by mol) is excellent in transparency, environmental aging property, and effective in improving heat-sealing property at low temperature and impact strength. A propylene elastomer is excellent in heat resistance, impact absorbing capacity, transparency, heat-sealing properties and anti-blocking properties.
    Type: Grant
    Filed: June 6, 1997
    Date of Patent: August 10, 1999
    Assignee: Mitsui Chemicals, Inc.
    Inventors: Daisuke Fukuoka, Takashi Tashiro, Koji Kawaai, Takashi Ueda, Yoshihisa Kiso, Akira Mizuno, Masaaki Kawasaki, Masaaki Itoh, Mikio Hashimoto
  • Patent number: 5932725
    Abstract: The present invention relates to a novel chromene compound having favorable photochromic properties, developing a color of a high density, exhibiting a small degree of initial color and permitting the color to quickly fade.
    Type: Grant
    Filed: April 30, 1998
    Date of Patent: August 3, 1999
    Assignee: Tokuyama Corporation
    Inventors: Yuichiro Kawabata, Tsuneyoshi Tanizawa, Tadashi Hara
  • Patent number: 5929140
    Abstract: A non-aqueous dispersion type coating resin composition which is excellent in pigment dispersibility and adhesive properties to various base material surfaces, can be made to have a high solid content, can be applied thick, and can form coat having good physical properties such as water resistance, alkali resistance and weatherability, and comprises(A) an organic solvent comprising an aliphatic hydrocarbon solvent as a main component,(B) an acrylic polymer which contains therein 0.2 to 30 weight % of a repeating unit represented by the following formula ##STR1## wherein, R.sup.1 represents a hydrogen atom or methyl group,m is an integer of 3 to 11, andn is a number of 1 to 10,and is soluble in the above organic solvent (A), and(C) polymer fine particles substantially insoluble in the above organic solvent (A).
    Type: Grant
    Filed: April 30, 1997
    Date of Patent: July 27, 1999
    Assignee: Nippon Carbide Kogyo Kabushiki Kaisha
    Inventors: Takao Fujii, Hiroaki Obata, Shunichi Yakita, Akira Kume, Hiroshi Serizawa, Takeshi Komatu
  • Patent number: 5929159
    Abstract: Corrosion resistant coatings are provided by aqueous-alcoholic acidic dispersions of the partial condensate of monomethyl silanol (by hydrolysis of monomethyl alkoxysilane) alone or in admixture with minor amounts of other silanol, e.g., gamma-glycidyloxy silanol, phenyl silanol, etc, wherein the dispersions contain divalent metal cations, e.g., Ca.sup.+2, in place of all or most of colloidal silica used in prior formulations of this type. The coatings may be applied to boat hulls, including aluminum hulls and are effective in preventing corrosion from salt water for extended periods.
    Type: Grant
    Filed: October 23, 1997
    Date of Patent: July 27, 1999
    Assignee: Adsil LC
    Inventors: John B. Schutt, Anthony A. Gedeon
  • Patent number: 5922812
    Abstract: A 4-methyl-1-pentene polymer composition having excellent heat resistance, releasability, gas permeability, impact resistance and other mechanical properties as well as heat sealability, prepared by melt mixing 40 to 97.5 parts by weight of a 4-methyl-1-pentene polymer (A), 2.5 to 60 parts by weight of a 1-butene polymer (B), and 1 to 100 parts by weight, based on 100 parts by weight of the total of (A) and (B), of a propylene polymer (C).
    Type: Grant
    Filed: September 12, 1997
    Date of Patent: July 13, 1999
    Assignee: Mitsui Chemicals, Inc.
    Inventors: Kojiro Kan, Akio Yamamoto
  • Patent number: 5922823
    Abstract: Disclosed is a process for preparing an ethylene-.alpha.-olefin-nonconjugated polyene random copolymer comprising random copolymerizing (a) ethylene, (b) an .alpha.-olefin of 3 or more carbon atoms and (c) a nonconjugated polyene in the presence of a metallocene catalyst containing a specific metallocene compound. The ethylene-.alpha.-olefin-nonconjugated polyene random copolymer prepared by the process has such properties that (i) the copolymer contains units derived from ethylene (a) and units derived from the .alpha.-olefin of 3 or more carbon atoms (b) in a molar ratio of 40/60 to 95/5 ?(a)/(b)!, (ii) the iodine value is 1 to 50, (iii) the intrinsic viscosity (.eta.) is more than 0.1 dl/g and less than 8.0 10 dl/g, (iv) the intensity ratio D of T.alpha..beta. to T.alpha..alpha. in the .sup.13 C-NMR spectrum, T.alpha..beta./T.alpha..alpha., is not more than 0.5, (v) the B value is 1.00 to 1.50, (vi) the glass transition temperature Tg is not higher than -50.degree. C., and (vii) the ratio g.eta.
    Type: Grant
    Filed: July 22, 1997
    Date of Patent: July 13, 1999
    Assignee: Mitsui Chemicals, Inc.
    Inventors: Toshihiro Sagane, Toshiyuki Tsutsui
  • Patent number: 5922860
    Abstract: This invention relates to compounds of the general formula ##STR1## or pharmaceutically salts thereof, wherein R.sup.1 and R.sup.2 each represent an OH group, R.sup.1 is located at the 1- or 2-position, R.sup.2 is located at the 10- or 11-position, R.sup.2 is located at the 11-position when R.sup.1 is located at the 1-position, and R.sup.2 is located at the 10-position when R.sup.1 is located at the 2-position. The compounds of the present invention have an excellent antitumor effect and are hence useful as antitumor agents in the field of medicine.
    Type: Grant
    Filed: January 7, 1998
    Date of Patent: July 13, 1999
    Assignee: Banyu Pharmaceutical Co., Ltd.
    Inventors: Katsuhisa Kojiri, Hisao Kondo, Hiroharu Arakawa, Mitsuru Ohkubo, Hiroyuki Suda
  • Patent number: 5919511
    Abstract: A process for the preparation of an embryo bud extract having high stability which comprises extracting defatted embryo buds with methanol or ethanol having a water content of not greater than 80% by weight. Drinks containing this embryo bud extract are very stable in that they produce no "sediment" and show no change in taste or flavor even after long-term storage, and are hence suitable for use as health drinks.
    Type: Grant
    Filed: July 19, 1996
    Date of Patent: July 6, 1999
    Inventor: Yoshihide Hagiwara
  • Patent number: 5916988
    Abstract: In accordance with the present invention, there are provided ethylene copolymers composed of structural units (a) derived from ethylene and structural units (b) derived from .alpha.-olefin of 3-20 carbon atoms, said ethylene copolymers having?A! a density of 0.85-0.92 g/cm.sup.3,?B! an intrinsic viscosity ?.eta.! as measured in decalin at 135.degree. C. of 0.1-10 dl/g,?C! a ratio (Mw/Mn) of a weight average molecular weight (Mw) to a number average molecular weight (Mn) as measured by GPC of 1.2-4, and?D! a ratio (MFR.sub.10 /MFR.sub.2) of MFR.sub.10 under a load of 10 kg to MFR.sub.2 under a load of 2.16 kg at 190.degree. C. of 8-50, and being narrow in molecular weight distribution and excellent in flowability.
    Type: Grant
    Filed: April 2, 1997
    Date of Patent: June 29, 1999
    Assignee: Mitsui Cehmicals, Inc.
    Inventors: Toshiyuki Tsutsui, Ken Yoshitsugu, Akinori Toyota
  • Patent number: 5916212
    Abstract: The present invention relates to a portable, hand held, self-contained cryosurgical probe system. In particular, the present invention relates to an improved portable, hand held cryosurgical probe system having easily changeable probes and cryogen sources wherein the cryogen can be provided in precharged cylinders mountable on the hand held unit and/or supplied from remote sources and which is capable of serving a plurality of probes via a multiprobe adapter. The present invention provides the flexibility of easily changeable probes and cryogen sources in a lightweight hand unit whereby different cryogens may be employed at different stages within a procedure or the cryogens may be mixed to vary the effective freeze capacity of the device.
    Type: Grant
    Filed: January 23, 1998
    Date of Patent: June 29, 1999
    Assignee: Cryomedical Sciences, Inc.
    Inventors: John G. Baust, John M. Baust, Lawrence Pottorf, Roy Cheeks, Hewu Ma, Chao-Min Zhang, Alan F. Rich, Richard J. Reinhart
  • Patent number: 5914208
    Abstract: The photosensitive material of the present invention is provided in contact with a developing roller and has a surface potential decay characteristic in which when the photosensitive material is charged to a surface potential of 800 V and is contacted with the developing roller to which a voltage (VR) is applied, the surface potential (VD) of the photosensitive material after contacting is represented by the formula (1):VD.gtoreq.800.times.EXP (0.00235.times.VR).By using this photosensitive material, a transverse black stripe in the tip of the transfer paper is prevented and it is possible to form an image having excellent image quality and image density.
    Type: Grant
    Filed: March 19, 1998
    Date of Patent: June 22, 1999
    Assignee: Mita Industrial Co., Ltd.
    Inventors: Toshiyuki Fukami, Nariaki Tanaka, Ichiro Yamazato, Eiichi Miyamoto, Tohru Ueno, Hiroshi Mishima
  • Patent number: 5912070
    Abstract: A laminated film superior in the heat resistance, shock resistance, moisture-barriering property and easy hand-tearability, which comprises one or more layers of a thermoplastic polyester resin (A), one or more layers of a resin based on cycloolefin (C) and one or more interposed layers of an adhesive (B) between layer (A) and layer (C), wherein the layer(s) of the thermoplastic polyester resin (A) and optionally the layer(s) of the resin based on cycloolefin (C) have been biaxially stretched and wherein the total thickness of the layer(s) of the thermoplastic polyester resin (A), the total thickness of the layer(s) of the adhesive (B) and the total thickness of the layer(s) based on cycloolefin (C) are 0.5-50 .mu.m, 0.5-20 .mu.m and 5-150 .mu.m, respectively.
    Type: Grant
    Filed: April 9, 1997
    Date of Patent: June 15, 1999
    Assignee: Mitsui Chemicals, Inc.
    Inventors: Kenji Miharu, Masaru Kokuryou, Yohzoh Yamamoto, Yasushi Amada
  • Patent number: 5911980
    Abstract: A mixture of lipophilic and amphiphilic/hydrophilic film-forming polymers of the formula (I): R(CO).sub.m O--(CH.sub.2 CHR.sup.1 O).sub.n --?OCNH--Z--NHCO.sub.2 (CH.sub.2 CHR.sup.2 O).sub.n' !.sub.p --OCNH--Z--NHCO.sub.2 --(CH.sub.2 CHR.sup.1 O).sub.n --(CO).sub.m R, wherein R represents (i) an alkyl, alkenyl or alkaryl hydrocarbyl group of from 1 to 3 carbon atoms or (ii) a polypropylene oxide group (PPO); R.sup.1 and R.sup.2, each, independently, represent a hydrogen atom, or a methyl or ethyl group; Z represents a divalent linking hydrocarbyl group; m is 0 or 1; n and n', are each, independently, a positive number; and p is >0, preferably p is 0 or 1, provide a skin substantive, occlusive moisture barrier covering for skin or hair. The compositions have a moisturizing effect by reducing transepidermal water loss.
    Type: Grant
    Filed: February 12, 1997
    Date of Patent: June 15, 1999
    Assignee: MacroChem Corporation
    Inventors: Carlos Samour, Scott F. Krauser
  • Patent number: 5912303
    Abstract: A terpolymer rubber prepared from ethylene, .alpha.-olefin having 3 to 20 carbon atoms and branched chain polyene of the formula ##STR1## wherein R.sup.1 represents C.sub.1 -C.sub.5 alkyl, and R.sup.2 and R.sup.3 represent hydrogen atom or C.sub.1 -C.sub.5 alkyl, such as, for example, 6,7-dimethyl-4-ethylidene-1,6-octadiene, 6,7-dimethyl-4-ethylidene-1,6-nonadiene, and 9-methyl-4-ethylidene-1,8-decadiene; when added to a rubber (diene rubber, nitrile rubber or random copolymer rubber from ethylene, C.sub.3 -C.sub.20 .alpha.-olefin, and optionally a nonconjugated diene) provides curable rubber compositions having rapid vulcanization rates, for example, as lows as about 7 to 10 seconds. The diene rubber compositions also have excellent resistances to weather,ozone and heat aging while maintaining excellent mechanical strength characteristics. The nitrile rubber compositions also have excellent oil resistance.
    Type: Grant
    Filed: May 23, 1996
    Date of Patent: June 15, 1999
    Assignee: Mitsui Chemicals, Inc.
    Inventors: Hidenari Nakahama, Masaaki Kawasaki, Tetsuo Tojo, Totshiyuki Tsutsui, Toshihiro Sagane
  • Patent number: 5912384
    Abstract: Color-stabilized basic monomers are provided. Said basic monomers are obtained by adding, to a basic monomer ?e.g. an N,N-dialkylaminoalkyl (meth)acrylate or an N,N-dialkylaminoalkyl (meth)acrylamide!, at least one member selected from the group consisting of amido group-containing compounds, phosphorous acid esters, phosphoric acid esters and phosphines and at least one phenol compound represented by the general formula: ##STR1## wherein R.sup.5, R.sup.6, R.sup.8 and R.sup.9 are each independently a hydrogen atom or an alkyl group having 1 to 4 carbon atoms; and R.sup.7 is a hydrogen atom, an alkyl group having 1 to 4 carbon atoms or an alkoxy group having 1 to 4 carbon atoms. The color-stabilized basic monomers are more resistant to coloration when they are handled under such conditions that the oxygen concentration in the gas phase contacting therewith is 0.01 to 10% by volume.
    Type: Grant
    Filed: December 29, 1997
    Date of Patent: June 15, 1999
    Assignee: Nippon Shokubai Co., Ltd.
    Inventor: Hideaki Nagano