Abstract: A sulfonic acid salt of an acyloxyalkylamine is prepared by reaction of an organic acid or amino-acid with a sulfonic acid salt of an alkanolamine. Isocyanates are prepared therefrom by reaction with phosgene.

Abstract: A method is disclosed for improving the solubility of Lewis acid dyes including metal chelate dyes and acid dyes, in solvents employing a copolymer based on a monomer containing a 5- or 6-membered heterocyclic tertiary amine. Dye solutions prepared by this process are useful in dyeing leather, in dyeing coatings and plastic articles, and are especially useful in combination with reactive urethane systems.

Abstract: By conducting solution polymerization in the presence of minor amounts of water, higher molecular weight polymers are obtained.

Abstract: A procedure is provided for producing a wound dressing having a crushed or uncrushed foam bonded to a woven, knit or nonwoven absorbent layer, particularly woven cotton gauze. The foam is self-bonded to the absorbent layer, i.e., no adhesive is needed to bond the foam. The foam may be applied by one of several methods. One procedure comprises applying a thin layer of foamed latex on a release medium. The dry foam, still on the release paper, is then simultaneously crushed and transfer bonded to the absorbent layer. A second method comprises applying the foam directly on the absorbent layer and crushing if desired. A third method comprises applying unfoamed material on the fabric and then causing foaming by the use of blowing agents then crushing if desired.

Abstract: Substituted phosphoramidates of the general formula: ##STR1## and their pharmaceutically acceptable metal salts and metal salt complexes, compositions containing them, and methods of employing them as anthelmintics are disclosed.

Abstract: Acetyl- and carbalkoxythioureidobenzophenones having a substituted amine adjacent to the thioureido radical are disclosed as having anthelmintic and antifungal activity.

Abstract: Fibers in non-woven fibrous products are bonded together by a binder comprising a heat-cured product of a water insoluble copolymer of (i) an N-methylolamide which is N-methylolacrylamide or N-methylolmethacrylamide, and (ii) an acrylic acid ester of acrylic acid or methacrylic acid and a C.sub.1 to C.sub.8 alkanol, modified with (iii) a polyalkylene glycol of the formulaHO--(RO).sub.n --Hwherein R is an alkylene group of 2 to 6 carbon atoms and n is a number having an average value of 4 to 50. Preferred acrylic acid esters are ethyl acrylate and butyl acrylate, and the preferred polyalkylene glycol is a polyethylene glycol characterized by a molecular weight in the range of 300 to 2000. The copolymer may also contain units derived from unsaturated aliphatic carboxylic acids. Preferably the copolymer contains units derived from itaconic acid.

Abstract: The present invention is concerned with the radioimmunoassay (RIA) procedure for assaying body fluid content of an antigenic substance which may either be an antigen itself or a hapten capable of being converted, such as by means of reaction with a protein, to an antigenic material. The present invention is concerned with a novel and improved modification of a double-antibody RIA technique in which there is a first antibody that is specific to the antigenic substance suspected to be present in a body fluid from which the assay is intended. The second antibody, however, is not specific to the antigenic substance or analyte, but is an antibody against the first antibody.

Abstract: Hydrocurable compositions of a hydroxy(polyalkylenecarbonyloxy)alkyleneoxazolidine and a polyfunctional isocyanate are disclosed. The compositions are useful in forming films, paints, coatings, fibers, seamless flooring, coatings, impregnants and adhesives for natural and synthetic materials. The compositions are prepared by treating a hydroxy(polyalkylenecarbonyloxy)alkyleneoxazolidine with a polyfunctional isocyanate or by treating a bisoxazolidine isocyanate prepolymer with a polyfunctional isocyanate.

Abstract: Arylaminoalkylthioamides and salts thereof wherein the benzene ring is substituted with halo, alkyl, lower alkoxy or 1,3-butadienylene are disclosed. The compounds are prepared by the reaction of the correspondingly substituted arylaminoalkylnitrile with hydrogen sulfide. The products are antisecretory agents useful in the treatment of ulcers.

Abstract: Hydrocurable compositions of a hydroxy(polyalkylenecarbonyloxy)alkyleneoxazolidine and a polyfunctional isocyanate are disclosed. The compositions are useful in forming films, paints, coatings, fibers, seamless flooring, coatings, impregnants and adhesives for natural and synthetic materials. The compositions are prepared by treating a hydroxy(polyalkylenecarbonyloxy)alkyleneoxazolidine with a polyfunctional isocyanate or by treating a bisoxazolidine isocyanate prepolymer with a polyfunctional isocyanate.

Abstract: A method for leveling latex polishes which comprises treating said polishes with a salt of partially hydrolyzed polymer of methacrylic ester wherein said polymer has an average chain length of from about 6 to about 20 mer units.

Abstract: Thioureas of the general structure Ary1NHC(S)-NR.sup.1 R.sup.2 are useful as antidiarrheal, antimotility or antisecretory agents. Particularly useful are those wherein Aryl is 2-methylphenyl and NR.sup.1 R.sup.2 is NHCH.sub.2 CH.sub.2 OH.

Abstract: The present invention is concerned with new and improved binders for the production of foamed or cellular articles which have a high degree of absorbency, and retain their bonded character as well as absorbency through numerous wash-dry cycles. The cellular articles are bonded by a novel self-cross-linking binder comprising a copolymer of (a) N-methylol-amine or -amide units, (b) sulfonic acid units which contain no basic nitrogen atoms or group, and (c) certain acrylic units of neutral but mildly hydrophilic character which contain no basic nitrogen atoms or group.

Abstract: A method for treating exocrine pancreatic insufficiency is disclosed. The method comprises the administration of a stable solid medicinal preparation containing finely particulated lipase intimately admixed with Hammarsten's casein and a tabletting lubricant, whereby a hydraulic pressure of about 2000 to about 5000 psi is employed.

Abstract: The present invention is concerned with the production of novel derivatives of thyroid hormones which are useful in the radioimmunoassay (RIA) of such hormones. The invention is particularly concerned with derivatives of thyroxine and triiodothyronine which contain an additional phenol group which is readily iodinatable so that the phenol conjugate can be readily tagged with a radioactive iodine isotope, such as .sup.125 I or .sup.131 I, without detrimentally interfering with the ability of the tagged conjugate so competitively bind with the naturally occurring thyroid hormone in the biological liquid to be analyzed by RIA technique. The invention is also concerned with the iodine-tagged derivatives or conjugates.

Abstract: The present invention is concerned with novel derivatives of cyanocobalamin (vitamin B.sub.12), especially of the monocarboxylic acid hydrolysates thereof, by which (1) an antigenic conjugate thereof with a protein is obtainable and (2) a readily iodinatable aromatic ring can be introduced while retaining in each instance, the essential constitution of cyanocobalamin to such an extent that (a) the antigenic protein conjugate, when introduced into the blood stream of a vertebrate, causes the formation of an antibody which is specific to the cyanocobalamin portion of the conjugate and (b) unmodified cyanocobalamin and the second-mentioned derivative when tagged or labeled with radioactive-iodine competitively bind on the aforementioned antibody. Thus, the present invention provides cyanocobalamin derivatives which are quite useful in radioimmunoassay (RIA) of vitamin B.sub.12.

Abstract: Macroreticular resins have shown biological activity for gallstone removal and lowering serum cholesterol by selective adsorption of cholesterol from the bile.

Abstract: Thioureas of the general structure ArylNHC(S)-NR.sup.1 R.sup.2 are useful as antidiarrheal, antimotility or antisecretory agents. Particularly useful are those wherein Aryl is 2-methylphenyl and NR.sup.1 R.sup.2 is NHCH.sub.2 CH.sub.2 OH.

Abstract: A procedure is provided for producing a laminate having a textile backing, a crushed, thermoset plastic foam bonded thereto, and a transparent polymeric film, preferably also a thermoset, which may be printed or colored overall overlying the foam. The structure is self-bonded, i.e., no adhesive is used to bond the laminate to one another. The preferred procedure is to apply a thin layer of foamed latex of a thermosettable polymer on a textile followed by drying the foam, the thickness of the foam being between about 10 mils and 150 mils. The transparent film, preferably thermosetting, is suitably formed by casting a latex upon a release surface such as silicone release paper and drying the same without causing thermosetting (if a thermosettable polymer is utilized). The dry film, still on the release paper, is then suitably coated or printed with a decorative design. The decorated side of the film is then placed against the dried foam layer and bonded thereto by pressure.