Abstract: A thiolsulfonate is reacted with an aminecarbodithioate salt to give an aminecarbotrithioate product. The products of this invention have biological activity, particularly in controlling microorganisms and other pests.

Abstract: 2-Nitroimidazole derivatives of the general formula ##SPC1##Wherein R is a lower alkyl group and Y is a member of the group consisting of --CH.sub.2 OH, --CHO, CH.sub.3 CO--, vinyl, formylvinyl, styryl, substituted iminomethyl, 2-benzimidazolyl and 5-amino-1,3,4-thiadiazol-2-yl. The term "lower alkyl" designates aliphatic groups of from 1 to 4 carbon atoms; the term "substituted iminomethyl" designates nitrogen-containing functional derivatives of the aldehydic group. The compounds have antimicrobial activity.

Abstract: Process for preparing an .alpha.-aminoalcohol of formula ##EQU1## wherein R represents hydrogen or alkyl of from 1 to 5 carbon atoms, which comprises contacting a compound of formula ##EQU2## wherein R has the same meaning as above, with an alcohol of formula R'-OH wherein R' represents benzyl or the group ##EQU3## in which R" and R"' are independently selected from hydrogen and alkyl of from 1 to 4 carbon atoms in an organic solvent, in the presence of a basic catalyst, at from about 140.degree. to about 170.degree.C., treating the obtained product of formula ##EQU4## wherein R and R' have the above meanings, with at least an equimolecular amount of a p-toluene-sulfonyl halide, at from about -5.degree. to about 20.degree.C. in the presence of a tertiary organic nitrogen-containing base and reacting in a closed system the resulting compound of formula ##EQU5## wherein R and R' are as above defined, with an excess of gaseous ammonia, in the presence of an inert organic solvent, at from about 95.degree.

Abstract: Bis(dichloroacetoxy)iodobenzenes and bis(trichloroacetoxy)iodobenzenes corresponding to the formulas ##SPC1##Wherein X represents hydrogen, a lower alkyl, a lower alkoxy, a halo, a nitro, a trifluoromethyl, a carboxyl, an amido or a loweralkylcarboxylate group. They are prepared by reacting the corresponding iodosobenzenes with dichloroacetic acid or trichloroacetic acid at substantially room temperature. The compounds are useful as intermediates for the preparation of antimicrobial iodonium salts.

Abstract: 5,6,7,7A-Tetrahydro-1H-pyrrolo[1,2-c]imidazole-1,3-(2H)-diones of the formula ##SPC1##In which R is phenyl, substituted phenyl or cyclohexyl, X is oxygen or sulfur and R.sub.1 is hydroxy, lower alkoxy, di-lower alkylamino-lower alkoxy, an --NR.sub.2 R.sub.3 radical wherein R.sub.2 and R.sub.3 each independently represents hydrogen, lower alkyl, hydroxy-lower alkyl, phenyl, substituted phenyl, benzyl or together with the adjacent nitrogen atom represent a pyrrolidino, a piperidino, a morpholino or a piperazino radical. The compounds of the invention are useful as C.N.S. depressants and in particular as tranquilizing and anxiolytic agents.

Abstract: Antibiotic activities produced by a variety of Streptosporangium vulgare named Streptosporangium vulgare var. antibioticum var. nov. ATCC 21906. The antibiotic complex contains at least the active fractions named A, B and C.

Abstract: 3,4-Dihalo-2,5-thiophenedicarbonitriles of the formula ##SPC1##Wherein each X independently is chloro or bromo. The compounds have plant fungicidal activity.

Abstract: The compounds of the formula ##SPC1##In which R is lower alkyl, lower alkoxy or halo, x is an integer from 0 to 2, n is an integer from 0 to 3, Y is halo and R.sub.1 and R.sub.2 independently are hydrogen, lower alkyl, phenyl or substituted phenyl, or, together with the nitrogen atom, form a heterocyclic ring also containing up to one oxygen atom in the heterocycle. The compounds in which x is 0 are prepared by adding chlorine or bromine to a 1-arylthiomethanesulfonamide in the presence of pyridine to form the 1-arylthio-1, 1-dihalomethanesulfonamide. The compounds in which x is 1 or 2 is prepared by adding sodium hypochlorite or sodium hypobromite to a 1-(arylsulfinyl)methane-sulfonamide or a 1-(arylsulfonyl)methanesulfonamide to form the 1-(arylsulfinyl)-1,1-dihalomethanesulfonamide or 1-(arylsulfonyl)-1,1-dihalomethanesulfonamide, respectively. The compounds are useful as antimicrobial agents.

Abstract: The present invention is concerned with novel antimicrobial thienyliodonium salts and methods and compositions employing the same, and is particularly directed to a class of thienyliodonium salts which are of value as antimicrobials and microbicides for the control of many bacterial organisms such as the gram-negative and gram-positive types, the molds, the mildews, the fungi and the slimes, and are of particular value for the preservation of paper, plaster, wallboards, fabric, textiles, cooling waters, plasticizers, latices, polymers, resins, adhesives, inks, paints, fuels, cutting oils, greases, seeds, terrestrial plants, detergents, soaps, shampoos and wood.

Abstract: Concerns compounds of the formula ##SPC1##Wherein R.sub.1 is a 1 to 6 carbon atom alkyl, benzyl, halobenzyl, lower alkylbenzyl, nitrobenzyl, alkenyl, haloalkenyl, 2-(lower alkylthio)lower alkyl or cyclohexylmethyl group, R.sub.2 is hydrogen, ammonium or alkali metal and n is an integer from 0 to 2. The compounds are prepared by reacting an alkali metal salt of 3-hydroxy-5,5-dimethyl-2-cyclohexen-1-one with a thiolsulfonate. The compounds are useful as plant growth regulators.

Abstract: Aminopropanols with .beta.-blocking activity having the general formula ##SPC1##Wherein R is hydrogen, C.sub.1 -C.sub.4 alkyl or hydroxy-(C.sub.2 -C.sub.4) alkyl, R.sub.1 is C.sub.1 -C.sub.4 alkyl or hydroxy-(C.sub.2 -C.sub.4) alkyl; R.sub.2 and R.sub.3 each independently represent hydrogen or C.sub.1 -C.sub.2 alkyl, R.sub.4 is hydrogen or alkoxy of 1 to 4 C, n is the number 1 or 2; and their pharmaceutically acceptable acid addition salts.

Abstract: The present invention is concerned with new derivatives of 3-formylrifamycin SV. More particularly the invention relates to O-substituted oximes of 3-formylrifamycin SV of formula I. ##SPC1##wherein R is selected from the group consisting of alkyl of at least 2 carbon atoms, alkenyl, alkynyl, cycloalkyl, alkoxyalkyl, cycloalkoxyalkyl, hydroxyalkyl, carboxyalkyl, carboalkoxyalkyl, carbamylalkyl, cyanoalkyl, nitroalkyl, aryloxyalkyl, aralkoxyalkyl, heterocycloxyalkyl, aminoalkyl, mono- and di-lower alkylaminoalkyl, substituted benzyl, mono- or poly-aryl substituted C.sub.2 -C.sub.8 alkyl and lower alkyl substituted with mono- or polynuclear heterocyclic rings containing at least one 1 to 3 heteroatom selected from oxygen, nitrogen and sulfur, with the exclusion of morpholine; R.sub.1 is H or CH.sub.3 CO; and the derivatives of the same oximes hydrogenated in at least one of the positions 16, 17; 18, 19; and 28, 29. These compounds have antimicrobial activity.

Abstract: This invention concerns sulfur-containing hydroxy pyrones corresponding to the formula ##SPC1##Wherein M is H or alkali metal, R is methyl, R' is hydrogen, alkyl, phenyl, halophenyl, nitrophenyl, loweralkylphenyl, benzyl, phenethyl, naphthylmethyl, halobenzyl, loweralkylbenzyl, nitrobenzyl, propargyl, allyl, cyclohexyl loweralkyl, (loweralkylthio)-loweralkyl or adamantyl and n is 0 to 2. The compounds are prepared by reacting the mono-alkali metal salt of 4-hydroxy-6-methyl-2-pyrone with an appropriate thiosulfonate, advantageously in the presence of an organic solvent. The compounds have utility as plant growth stunters and as antimicrobial agents.