Patents Represented by Attorney Thomas L. Johnson
  • Patent number: 4387084
    Abstract: A process for treating thiosulfate containing liquors such as coke oven gas scrubbing liquors by first adding acid, preferably sulfuric acid, to convert thiosulfate to elemental sulfur and bisulfite, separating and removing the elemental sulfur, and subjecting the remaining liquor to wet oxidation.
    Type: Grant
    Filed: October 26, 1981
    Date of Patent: June 7, 1983
    Assignee: Sterling Drug Inc.
    Inventors: Bruce L. Brandenburg, Gerald L. Bauer
  • Patent number: 4384959
    Abstract: A continuous process for wet oxidation of aqueous liquor containing combustible matter using oxygen or oxygen enriched gas. An inert diluent gas is injected into the aqueous liquor or reactor off-gas such that oxygen in the gas phase is diluted by the sum of generated water vapor, produced carbon dioxide and injected inert gas to a concentration less than required for spontaneous combustion at every location in the system having surfaces not continually exposed to a continuous liquid water phase.
    Type: Grant
    Filed: December 29, 1980
    Date of Patent: May 24, 1983
    Assignee: Sterling Drug Inc.
    Inventors: Gerald L. Bauer, Gary S. Dahmes, Ajit K. Chowdhury
  • Patent number: 4379936
    Abstract: 3.alpha.-Benzoylamino-2.beta.-hydroxy-nortropanes substituted in the 8-position by an alkoxycarbonyl or alkanoyl group, useful as analgesics, are prepared by reacting the corresponding 2.beta.,3.beta.-epoxy-nortropane with benzylamine in the presence of phenol.
    Type: Grant
    Filed: April 19, 1982
    Date of Patent: April 12, 1983
    Assignee: Sterling Drug Inc.
    Inventor: Robert L. G. Clarke
  • Patent number: 4372976
    Abstract: A novel antiviral agent, tert-butyl (3,4-dibenzyloxy)styryl ketone, is described.
    Type: Grant
    Filed: August 7, 1981
    Date of Patent: February 8, 1983
    Assignee: Sterling Drug Inc.
    Inventor: Guy D. Diana
  • Patent number: 4372940
    Abstract: A process and apparatus for treating thiosulfate containing liquors such as coke oven gas scrubbing liquors in two stages of wet oxidation with intermediate removal of elemental sulfur. Mild oxidation conditions in the first stage results in conversion of thiosulfate sulfur to elemental sulfur, which is removed prior to second stage wet oxidation of the liquors to substantially reduce the liquor oxygen demand.
    Type: Grant
    Filed: October 26, 1981
    Date of Patent: February 8, 1983
    Assignee: Sterling Drug Inc.
    Inventors: Bruce L. Brandenburg, Gerald L. Bauer
  • Patent number: 4357953
    Abstract: An apparatus for introducing powdered solids into a liquid stream at a controlled rate to form a slurry. Solids are metered to an eductor where they are educted into the liquid stream. An automatic cycle timer-controller purges eductor, hopper and piping of residual solids before solids flow is initiated, and following solids flow. Pressure sensors detect low water pressure and/or plugging, shutting off liquid and solids flow.
    Type: Grant
    Filed: February 26, 1981
    Date of Patent: November 9, 1982
    Assignee: Sterling Drug Inc.
    Inventor: Donald E. Patterson
  • Patent number: 4350599
    Abstract: An improvement in the wet oxidation of caustic waste liquors wherein carbon dioxide produced in the wet oxidation is recycled to raw caustic waste to neutralize the latter, thereby reducing the corrosive nature of the waste.
    Type: Grant
    Filed: December 29, 1980
    Date of Patent: September 21, 1982
    Assignee: Sterling Drug Inc.
    Inventor: Ajit K. Chowdhury
  • Patent number: 4349558
    Abstract: The compounds of the formulas ##STR1## where R and R' are lower-alkyl possess glucocorticoid activity, and are prepared by reacting the compound of the formula ##STR2## with the appropriate dienophile.
    Type: Grant
    Filed: February 19, 1981
    Date of Patent: September 14, 1982
    Assignee: Sterling Drug Inc.
    Inventor: Malcolm R. Bell
  • Patent number: 4349559
    Abstract: The compounds of formula ##STR1## where R is hydrogen or fluorine possess glucocorticoid activity, and are prepared by reacting a compound of the formula ##STR2## with 1,2,3-indantrione.
    Type: Grant
    Filed: February 19, 1981
    Date of Patent: September 14, 1982
    Assignee: Sterling Drug Inc.
    Inventors: Malcolm R. Bell, John L. Herrmann, Jr.
  • Patent number: 4341895
    Abstract: 3.alpha.-Benzylamino-2.beta.-hydroxy-nortropanes substituted in the 8-position by an alkoxycarbonyl or alkanoyl group, useful as analgesics, are prepared by reacting the corresponding 2.beta.,3.beta.-epoxy-nortropane with enzylamine in the presence of phenol.
    Type: Grant
    Filed: March 3, 1981
    Date of Patent: July 27, 1982
    Assignee: Sterling Drug Inc.
    Inventor: Robert L. Clarke
  • Patent number: 4330038
    Abstract: A process for enhanced oil recovery by gas injection into oil-bearing formations which comprises wet oxidizing combustible carbonaceous materials with oxygen, air or a mixture of oxygen and air to obtain a gas comprising a mixture of water vapor and carbon dioxide (and nitrogen in the event air is used), substantially free of oxides of sulfur and nitrogen; injecting said gaseous mixture into an oil-bearing formation to produce a mixture of oil and water; extracting said mixture of oil and water from the oil-bearing formation; separating the water from the latter mixture; and recycling the water to the wet oxidation reactor. Residual oil in the recycled water provides additional fuel for the wet oxidation reaction, and at the same time the need for costly water treatment is eliminated.
    Type: Grant
    Filed: May 14, 1980
    Date of Patent: May 18, 1982
    Assignee: Zimpro-AEC Ltd.
    Inventors: Charles L. Soukup, Richard K. Kerr
  • Patent number: 4312761
    Abstract: A process for dewatering slimes produced in mining and mineral processing operations whereby wet oxidation at 150.degree.-320.degree. C. renders the solids rapidly settleable. Sufficient oxygen is supplied to meet or exceed oxygen demand. Inorganic solids in the oxidized product are separated and optionally further dewatered to a friable solid. Clarified water is recycled to the mining, mineral processing or other operations, or treated further, or discharged to the environment. Steam resulting from the wet oxidation is utilized in the mining or mineral processing operations.
    Type: Grant
    Filed: November 20, 1980
    Date of Patent: January 26, 1982
    Assignee: Zimpro-AEC Ltd.
    Inventors: Wayne B. Gitchel, Richard K. Kerr
  • Patent number: 4307102
    Abstract: The compound of the formula ##STR1## possesses glucocorticoid activity, and is prepared by reacting the compound of the formula ##STR2## with 2-vinylpyridine.
    Type: Grant
    Filed: February 19, 1981
    Date of Patent: December 22, 1981
    Assignee: Sterling Drug Inc.
    Inventor: Malcolm R. Bell
  • Patent number: 4281130
    Abstract: Compounds of tropane (8-azabicyclo[3.2.1]octane) series having an aromatic substituent in the 2-position and a carboalkoxy group in the 3-position are prepared by reacting a tropane-3-carboxylate having a double bond in the 2,3-position with an aryl Grignard reagent. Transformations of the substituent on nitrogen are subsequently effected. Compounds where the 3-carboalkoxy group is in the exo configuration possess hypoglycemic activity, and those where the 3-carboalkoxy group is in the endo configuration possess narcotic antagonist activity.
    Type: Grant
    Filed: October 26, 1979
    Date of Patent: July 28, 1981
    Assignee: Sterling Drug Inc.
    Inventors: Robert L. Clarke, Sol J. Daum
  • Patent number: 4275201
    Abstract: Aryl substituted diketones and keto-esters, useful as antiviral agents and insecticides, are prepared by reacting an arylalkyl or arylalkenyl iodide with a metal salt of the appropriate diketone or keto-ester.
    Type: Grant
    Filed: February 14, 1979
    Date of Patent: June 23, 1981
    Assignee: Sterling Drug Inc.
    Inventor: Joseph C. Collins
  • Patent number: 4268678
    Abstract: 4-(Arylaliphatic)isoxazoles, having antiviral activity, are prepared by reacting with hydroxylamine a diketone of the formula Ar-Y-CH(CO-R).sub.2, wherein Ar is substituted phenyl, Y is (CH.sub.2).sub.n or O(CH.sub.2).sub.n, and R is lower-alkyl.
    Type: Grant
    Filed: September 4, 1979
    Date of Patent: May 19, 1981
    Assignee: Sterling Drug Inc.
    Inventors: Guy D. Diana, Philip M. Carabateas
  • Patent number: 4265747
    Abstract: Disinfection of aqueous media contaminated with microorganisms is effected by contacting said media with a gas phase in which a plasma is generated by focused laser radiation. Similarly, wastewaters containing organic susbstances are purified by contacting them with an oxygen-containing gas phase in which a plasma is generated by focused laser radiation which promotes oxidation of the organic substances to innocuous products.
    Type: Grant
    Filed: May 22, 1979
    Date of Patent: May 5, 1981
    Assignee: Sterling Drug Inc.
    Inventors: William M. Copa, Wayne B. Gitchel
  • Patent number: 4261928
    Abstract: 4-(Aryloxyalkyl)pyrazoles of the formula ##STR1## useful as antiviral agents, are prepared by reacting the corresponding diketones of the formula Ar--O--Alk--CH(COR')COR" with hydrazine or a substituted hydrazine H.sub.2 NNHR.
    Type: Grant
    Filed: October 24, 1979
    Date of Patent: April 14, 1981
    Assignee: Sterling Drug Inc.
    Inventors: Guy D. Diana, Philip M. Carabateas
  • Patent number: 4246284
    Abstract: Aminosulfonyl-substituted aryloxyalkyl diketones, useful as antiviral agents, are prepared by reacting a haloalkyl diketone with an alkali metal salt of a hydroxybenzenesulfonamide.
    Type: Grant
    Filed: November 5, 1979
    Date of Patent: January 20, 1981
    Assignee: Sterling Drug Inc.
    Inventors: Joseph C. Collins, Guy D. Diana
  • Patent number: 4244954
    Abstract: 9-Phenyl(or benzyl)acridines, 9-phenyl(or benzyl)-9-acridinols and acridinium compounds, useful as trypanosomacidal and antibacterial agents, are prepared from aminoalkoxy substituted 9-acridinones via reaction with the appropriate Grignard reagents or aryllithium. The intermediate aminoalkoxy substituted 9-acridinones, prepared from the corresponding halo or hydroxy substituted 9-acridinones, are useful as antiviral agents.
    Type: Grant
    Filed: October 2, 1978
    Date of Patent: January 13, 1981
    Assignee: Sterling Drug Inc.
    Inventor: John W. Schulenberg