Abstract: The present invention relates to detergent compositions comprising an enzyme preparation with substantial cellulytic activity, especially endoglucanase activity, at alkaline conditions which is enzyme composition is derived from or producible by a fungus selected from the Basidiomycetous families Coprinaceae and Bolbitiaceae, preferably from the group of strains belonging to the genera Psathyrella, Podaxis, Panaeolus, Coprinus and Bolbitius, more preferably from the group of strains belonging to the species Coprinus micaceus, Coprinus domesticus, Coprinus ephemerus, Coprinus disseminatus, Coprinus radians, Coprinus picaceus, Coprinus frisei, Coprinus subimpatiens, Psathyrella candolleana, Psathyrella prona, Panaeolus semiovatus, Podaxis pistillaris and Bolbitius aleuriatus; and a method for providing a stone-washed look to textiles, especially to cellulosic fabric such as denim, using the mentioned enzyme preparation; and a method for improving the drainage of paper pulp or the de-inking of recycled paper usi
Type:
Grant
Filed:
June 6, 1997
Date of Patent:
October 26, 1999
Assignee:
Novo Nordisk A/S
Inventors:
Lene Lange, Jack Bech Nielsen, Martin Schulein
Abstract: The invention deals with a process for providing a cellulosic material, such as a fabric or a paper and pulp product, with improved strength and/or shape-retention and/or anti-wrinkling properties, the process comprising contacting, in an aqueous medium, the cellulosic material with a xyloglucan endotransglycosylase (XET).
Abstract: A purified peroxidase obtained from a strain of Myxococcus, having a molecular weight of about 40 kDA as determined by SDS-PAGE, which is stable up to 60.degree. C. for 2 hours without loss of activity, and retains activity at pH 10.5.
Type:
Grant
Filed:
April 23, 1996
Date of Patent:
September 7, 1999
Assignee:
Novo Nordisk A/S
Inventors:
Carsten Sj.o slashed.holm, Iben N.o slashed.rrevang, Anders Hjelholt Pedersen
Abstract: DNA sequences encoding lipases and method for producing the lipases. The disclosed lipases are industrially useful in, for example, detergents, food processing, paper making, oil manufacturing.
Abstract: A lipolytic enzyme with high activity at alkaline pH in the absence of Ca.sup.++ can be obtained from strains of filamentous fungi belonging to the genus Absidia. The lipolytic enzymes are effective for improving the effect of detergents towards fatty soiling.
Abstract: This invention is in the field of detergent proteases obtainable from strains of a new Bacillus sp. I 612. Moreover, the invention is directed towards a process for the preparation of the protease, the use of the protease as a detergent enzyme, and detergent compositions comprising the protease of the invention.
Abstract: A method of treating fabrics, garments, or yarns comprising treating undyed fabric, garment, or yarn in an aqueous medium with an effective amount of a haloperoxidase, a halide source, and a hydrogen peroxide source. The treated fabric, garment, or yarn exhibits improved characteristics relative to untreated fabric, garment, or yarn, such as improved shrink-resistance.
Abstract: A process for simultaneously desizing and bleaching of a sized fabric containing starch or starch derivatives, which process comprises treating the fabric with a bleaching composition and an oxidation stable .alpha.-amylase.
Type:
Grant
Filed:
August 22, 1996
Date of Patent:
July 27, 1999
Assignee:
Novo Nordisk A/S
Inventors:
Annette Hanne Toft, Dorthe Marcher, Hanne H.o slashed.st Pedersen, Thomas Erik Nilsson
Abstract: An isolated nucleic acid constructs encoding cellulytic enzymes derived from a strain of Bacillus agaradherens, recombinant vectors and host cells comprising such constructs, and methods for obtaining cellulytic enzymes.
Type:
Grant
Filed:
September 13, 1996
Date of Patent:
July 13, 1999
Assignee:
Novo Nordisk A/S
Inventors:
Helle Outtrup, Claus Dambmann, Arne Agerlin Olsen, Henrik Bisg.ang.rd-Frantzen, Martin Schulein, Per Linaa Jorgensen, Mads E. Bjoernvad
Abstract: DNA sequences are disclosed encoding an enzyme exhibiting endoglucanase activity. The endoglucanase is useful in a variety of industrial processes requiring an alkaline cellulase.
Type:
Grant
Filed:
March 20, 1997
Date of Patent:
July 6, 1999
Assignee:
Novo Nordisk A/S
Inventors:
Martin Schulein, Karen Margrethe Oxenb.o slashed.ll, Lene Nonboe Andersen, S.o slashed.ren Flensted Lassen, Markus Sakari Kauppinen, Jack Bech Nielsen
Abstract: A DNA construct exhibiting .beta.-1,3-glucanase activity, including an expression vectors, cells harbouring the DNA construct or expression vector, a method of producing the enzyme, as well as the enzyme and preparations containing the enzyme.
Type:
Grant
Filed:
April 14, 1997
Date of Patent:
July 6, 1999
Assignee:
Novo Nordisk A/S
Inventors:
Pau Ferrer, Ivan Diers, Lisbeth Hedegaard, Torben Halkier, Juan A. Asenjo, Demitris Savva
Abstract: A process for providing improved localised variation in the color density of the surface of dyed fabrics by reducing backstaining, the process including treating a dyed fabric with a cellulytic enzyme in an aqueous liquor and adding a sufficient amount of chelating agent to the liquor to reduce the concentration of di- or trivalent cation to less than 20 mg/l.
Abstract: The present invention relates to an alkaline lipolytic enzyme derivable from a strain of Botryosphaeria or Guignardia, to a lipolytic enzyme-producing microbial strain, to methods for the production of lipolytic enzyme and to a detergent composition comprising the lipolytic enzyme.
Abstract: A DNA construct comprising a DNA sequence encoding a polypeptide having .alpha.-galactosidase activity, having the amino acid sequence of SEQ ID NO:3.
Abstract: A method for obtaining a cellulosic textile fabric having a strongly reduced tendency to pilling formation, preferably corresponding to a pilling note of at least 4, more preferably of at least 4.5, which method comprises treating the fabric with a cellulase capable of performing a partial hydrolysis of the fibre surface corresponding to a <2% weight loss based on the untreated cellulosic textile fabric. The cellulase is preferably a 43 kD endoglucanase derived from or producible by Humicola insolens, DSM 1800, SEQ ID NO:1, or a functional analogue of said cellulase such as a variant which is modified by substitution of one or more amino acid residues in one or more of the positions 8, 55, 58, 62, 67, 132, 147, 162, 221, 222, 223, 280; or modified by truncation, preferably genetically truncation, at any position from position 213.
Type:
Grant
Filed:
May 8, 1997
Date of Patent:
June 29, 1999
Assignee:
Novo Nordisk A/S
Inventors:
Henrik Lund, Hanne H.o slashed.st Pedersen
Abstract: The present invention relates to cellulases derived from the strain Myceliophthora thermophila and variants thereof comprising a core and optionally a C-terminal link consisting of 10 amino acids at the most, especially cellulases having a substrate binding cleft of a depth of at least 12 .ANG., exhibit enhanced enzyme activity in the alkaline pH range while exerting a moderate cellulolytic action on the cellulosic substrate and are, for example, useful in detergent compositions, especially for soil removal or color clarification or preventing backstaining; in fabric softeners; for bio-polishing of textiles; for drainage improvement of paper pulp; for deinking of old paper; for plant degradation.
Abstract: A therapeutic powder formulation suitable for pulmonary administration comprising particles composed of human insulin or any analogue or derivative thereof and an enhancer which enhances the absorption of insulin in the lower respiratory tract, wherein at least 50% by weight of the particles are crystalline.
Abstract: A method of providing zinc containing crystals of a protein derivative which has a lysine residue which carries a lipophilic substituent on the .epsilon.-amino group, said method comprising providing a solution of the protein derivative in an alkaline buffer, which further contains a zinc salt, adjusting the pH value of the solution to a value between 7 and 10, and isolating the crystals formed.
Type:
Grant
Filed:
February 2, 1998
Date of Patent:
April 27, 1999
Assignee:
Novo Nordisk A/S
Inventors:
Per Balschmidt, Jean Lesley Whittingham
Abstract: This invention is in the field of detergent proteases obtainable from a strain of a new Bacillus sp. ZI 315. Moreover, the invention is directed towards a process for the preparation of the protease, the use of the protease as detergent enzyme, and detergent compositions comprising the protease of the invention.