Patents Represented by Attorney Valeta Gregg, Esq.
  • Patent number: 5972665
    Abstract: The invention relates to novel thermostable pullulanases obtainable from Pyrodictium.
    Type: Grant
    Filed: May 13, 1997
    Date of Patent: October 26, 1999
    Assignee: Novo Nordisk A/S
    Inventors: Carsten Sj.o slashed.holm, Garabed Antranikian
  • Patent number: 5972872
    Abstract: The present invention relates to detergent compositions comprising an enzyme preparation with substantial cellulytic activity, especially endoglucanase activity, at alkaline conditions which is enzyme composition is derived from or producible by a fungus selected from the Basidiomycetous families Coprinaceae and Bolbitiaceae, preferably from the group of strains belonging to the genera Psathyrella, Podaxis, Panaeolus, Coprinus and Bolbitius, more preferably from the group of strains belonging to the species Coprinus micaceus, Coprinus domesticus, Coprinus ephemerus, Coprinus disseminatus, Coprinus radians, Coprinus picaceus, Coprinus frisei, Coprinus subimpatiens, Psathyrella candolleana, Psathyrella prona, Panaeolus semiovatus, Podaxis pistillaris and Bolbitius aleuriatus; and a method for providing a stone-washed look to textiles, especially to cellulosic fabric such as denim, using the mentioned enzyme preparation; and a method for improving the drainage of paper pulp or the de-inking of recycled paper usi
    Type: Grant
    Filed: June 6, 1997
    Date of Patent: October 26, 1999
    Assignee: Novo Nordisk A/S
    Inventors: Lene Lange, Jack Bech Nielsen, Martin Schulein
  • Patent number: 5968813
    Abstract: The invention deals with a process for providing a cellulosic material, such as a fabric or a paper and pulp product, with improved strength and/or shape-retention and/or anti-wrinkling properties, the process comprising contacting, in an aqueous medium, the cellulosic material with a xyloglucan endotransglycosylase (XET).
    Type: Grant
    Filed: May 26, 1998
    Date of Patent: October 19, 1999
    Assignee: Novo Nordisk A/S
    Inventors: Lene Venke Kofod, Henrik Lund
  • Patent number: 5948661
    Abstract: A purified peroxidase obtained from a strain of Myxococcus, having a molecular weight of about 40 kDA as determined by SDS-PAGE, which is stable up to 60.degree. C. for 2 hours without loss of activity, and retains activity at pH 10.5.
    Type: Grant
    Filed: April 23, 1996
    Date of Patent: September 7, 1999
    Assignee: Novo Nordisk A/S
    Inventors: Carsten Sj.o slashed.holm, Iben N.o slashed.rrevang, Anders Hjelholt Pedersen
  • Patent number: 5942431
    Abstract: DNA sequences encoding lipases and method for producing the lipases. The disclosed lipases are industrially useful in, for example, detergents, food processing, paper making, oil manufacturing.
    Type: Grant
    Filed: July 10, 1997
    Date of Patent: August 24, 1999
    Assignee: Novo Nordisk A/S
    Inventors: Tadashi Yoneda, Harumi Takada, Kei Ohno, Junji Sasuga
  • Patent number: 5929017
    Abstract: A lipolytic enzyme with high activity at alkaline pH in the absence of Ca.sup.++ can be obtained from strains of filamentous fungi belonging to the genus Absidia. The lipolytic enzymes are effective for improving the effect of detergents towards fatty soiling.
    Type: Grant
    Filed: April 24, 1997
    Date of Patent: July 27, 1999
    Assignee: Novonordisk A/S
    Inventors: Erik Gormsen, Naoko Ikegami, Masanobu Abo, Shinobu Takagi, Noriko Tsutsumi, Torben Halkier
  • Patent number: 5928929
    Abstract: This invention is in the field of detergent proteases obtainable from strains of a new Bacillus sp. I 612. Moreover, the invention is directed towards a process for the preparation of the protease, the use of the protease as a detergent enzyme, and detergent compositions comprising the protease of the invention.
    Type: Grant
    Filed: July 2, 1997
    Date of Patent: July 27, 1999
    Assignee: Novo Nordisk A/S
    Inventors: Helle Outtrup, Lars Sparre Conrad
  • Patent number: 5928380
    Abstract: A method of treating fabrics, garments, or yarns comprising treating undyed fabric, garment, or yarn in an aqueous medium with an effective amount of a haloperoxidase, a halide source, and a hydrogen peroxide source. The treated fabric, garment, or yarn exhibits improved characteristics relative to untreated fabric, garment, or yarn, such as improved shrink-resistance.
    Type: Grant
    Filed: June 8, 1998
    Date of Patent: July 27, 1999
    Assignee: Novo Nordisk A/S
    Inventors: Jacob Winkler, Lars Sparre Conrad
  • Patent number: 5928381
    Abstract: A process for simultaneously desizing and bleaching of a sized fabric containing starch or starch derivatives, which process comprises treating the fabric with a bleaching composition and an oxidation stable .alpha.-amylase.
    Type: Grant
    Filed: August 22, 1996
    Date of Patent: July 27, 1999
    Assignee: Novo Nordisk A/S
    Inventors: Annette Hanne Toft, Dorthe Marcher, Hanne H.o slashed.st Pedersen, Thomas Erik Nilsson
  • Patent number: 5922586
    Abstract: An isolated nucleic acid constructs encoding cellulytic enzymes derived from a strain of Bacillus agaradherens, recombinant vectors and host cells comprising such constructs, and methods for obtaining cellulytic enzymes.
    Type: Grant
    Filed: September 13, 1996
    Date of Patent: July 13, 1999
    Assignee: Novo Nordisk A/S
    Inventors: Helle Outtrup, Claus Dambmann, Arne Agerlin Olsen, Henrik Bisg.ang.rd-Frantzen, Martin Schulein, Per Linaa Jorgensen, Mads E. Bjoernvad
  • Patent number: 5919691
    Abstract: DNA sequences are disclosed encoding an enzyme exhibiting endoglucanase activity. The endoglucanase is useful in a variety of industrial processes requiring an alkaline cellulase.
    Type: Grant
    Filed: March 20, 1997
    Date of Patent: July 6, 1999
    Assignee: Novo Nordisk A/S
    Inventors: Martin Schulein, Karen Margrethe Oxenb.o slashed.ll, Lene Nonboe Andersen, S.o slashed.ren Flensted Lassen, Markus Sakari Kauppinen, Jack Bech Nielsen
  • Patent number: 5919688
    Abstract: A DNA construct exhibiting .beta.-1,3-glucanase activity, including an expression vectors, cells harbouring the DNA construct or expression vector, a method of producing the enzyme, as well as the enzyme and preparations containing the enzyme.
    Type: Grant
    Filed: April 14, 1997
    Date of Patent: July 6, 1999
    Assignee: Novo Nordisk A/S
    Inventors: Pau Ferrer, Ivan Diers, Lisbeth Hedegaard, Torben Halkier, Juan A. Asenjo, Demitris Savva
  • Patent number: 5919272
    Abstract: A process for providing improved localised variation in the color density of the surface of dyed fabrics by reducing backstaining, the process including treating a dyed fabric with a cellulytic enzyme in an aqueous liquor and adding a sufficient amount of chelating agent to the liquor to reduce the concentration of di- or trivalent cation to less than 20 mg/l.
    Type: Grant
    Filed: September 18, 1995
    Date of Patent: July 6, 1999
    Assignee: Novo Nordisk A/S
    Inventor: Jack Bech Nielsen
  • Patent number: 5919746
    Abstract: The present invention relates to an alkaline lipolytic enzyme derivable from a strain of Botryosphaeria or Guignardia, to a lipolytic enzyme-producing microbial strain, to methods for the production of lipolytic enzyme and to a detergent composition comprising the lipolytic enzyme.
    Type: Grant
    Filed: August 28, 1997
    Date of Patent: July 6, 1999
    Assignee: Novo Nordisk A/S
    Inventors: Satoshi Hirayama, Torben Halkier
  • Patent number: 5919690
    Abstract: A DNA construct comprising a DNA sequence encoding a polypeptide having .alpha.-galactosidase activity, having the amino acid sequence of SEQ ID NO:3.
    Type: Grant
    Filed: September 12, 1995
    Date of Patent: July 6, 1999
    Assignee: Novo Nordisk A/S
    Inventors: Inge Helmer Knap, Carsten M. Hjort, Torben Halkier, Lene Venke Kofod
  • Patent number: 5916798
    Abstract: A method for obtaining a cellulosic textile fabric having a strongly reduced tendency to pilling formation, preferably corresponding to a pilling note of at least 4, more preferably of at least 4.5, which method comprises treating the fabric with a cellulase capable of performing a partial hydrolysis of the fibre surface corresponding to a <2% weight loss based on the untreated cellulosic textile fabric. The cellulase is preferably a 43 kD endoglucanase derived from or producible by Humicola insolens, DSM 1800, SEQ ID NO:1, or a functional analogue of said cellulase such as a variant which is modified by substitution of one or more amino acid residues in one or more of the positions 8, 55, 58, 62, 67, 132, 147, 162, 221, 222, 223, 280; or modified by truncation, preferably genetically truncation, at any position from position 213.
    Type: Grant
    Filed: May 8, 1997
    Date of Patent: June 29, 1999
    Assignee: Novo Nordisk A/S
    Inventors: Henrik Lund, Hanne H.o slashed.st Pedersen
  • Patent number: 5912157
    Abstract: The present invention relates to cellulases derived from the strain Myceliophthora thermophila and variants thereof comprising a core and optionally a C-terminal link consisting of 10 amino acids at the most, especially cellulases having a substrate binding cleft of a depth of at least 12 .ANG., exhibit enhanced enzyme activity in the alkaline pH range while exerting a moderate cellulolytic action on the cellulosic substrate and are, for example, useful in detergent compositions, especially for soil removal or color clarification or preventing backstaining; in fabric softeners; for bio-polishing of textiles; for drainage improvement of paper pulp; for deinking of old paper; for plant degradation.
    Type: Grant
    Filed: September 9, 1996
    Date of Patent: June 15, 1999
    Assignee: Novo Nordisk A/S
    Inventors: Claus von der Osten, Martin Schulein
  • Patent number: 5898028
    Abstract: A therapeutic powder formulation suitable for pulmonary administration comprising particles composed of human insulin or any analogue or derivative thereof and an enhancer which enhances the absorption of insulin in the lower respiratory tract, wherein at least 50% by weight of the particles are crystalline.
    Type: Grant
    Filed: March 20, 1998
    Date of Patent: April 27, 1999
    Assignee: Novo Nordisk A/S
    Inventors: Steen Jensen, Philip Hansen
  • Patent number: 5898067
    Abstract: A method of providing zinc containing crystals of a protein derivative which has a lysine residue which carries a lipophilic substituent on the .epsilon.-amino group, said method comprising providing a solution of the protein derivative in an alkaline buffer, which further contains a zinc salt, adjusting the pH value of the solution to a value between 7 and 10, and isolating the crystals formed.
    Type: Grant
    Filed: February 2, 1998
    Date of Patent: April 27, 1999
    Assignee: Novo Nordisk A/S
    Inventors: Per Balschmidt, Jean Lesley Whittingham
  • Patent number: 5888797
    Abstract: This invention is in the field of detergent proteases obtainable from a strain of a new Bacillus sp. ZI 315. Moreover, the invention is directed towards a process for the preparation of the protease, the use of the protease as detergent enzyme, and detergent compositions comprising the protease of the invention.
    Type: Grant
    Filed: July 7, 1997
    Date of Patent: March 30, 1999
    Assignee: Novo Nordisk A/S
    Inventors: Helle Outtrup, Lars Sparre Conrad