Patents Represented by Law Firm Wegner & Bretschneider
  • Patent number: 4965068
    Abstract: The present invention involves a polyvalent hyperimmunoglobulin preparation having activity against gram negative and gram positive bacteria. Such a polyvalent hyperimmunoglobulin preparation is prepared from plasma, serum or whole blood from donors. Donor selection is based upon titer against E. coli J5 antigen or against lipid A antigen.
    Type: Grant
    Filed: June 23, 1989
    Date of Patent: October 23, 1990
    Assignee: Biotest Pharma GmbH
    Inventors: Wolfgang Stephan, Herbert Dichtelmuller, Michael Kloft
  • Patent number: 4964206
    Abstract: Disclosed is an intraocular lens comprising a lens element and a plurality of haptics extending therefrom, at least one of the haptics having an anchoring filament with an enlarged complete or partial mushroom-shaped end fixedly disposed inside a passage in the lens element. Also disclosed is a method for fixing a haptic having an anchoring filament to a lens element in a soft intraocular lens comprising the steps of (a) forming in the lens element a passage having a width that is less than the greatest width of the anchoring filament, (b) lubricating the anchoring filament of the haptic, the passage in the lens element, or both, (c) inserting the anchoring filament end-first into the passage, and (d) washing the intraocular lens to remove the lubricant.
    Type: Grant
    Filed: April 12, 1990
    Date of Patent: October 23, 1990
    Assignee: Minnesota Mining and Manufacturing Company
    Inventors: Randall L. Knoll, James E. Aysta, Wilhelm Lewon
  • Patent number: 4965401
    Abstract: The process for the preparation of the E isomers of the compounds of formula A: ##STR1## in which R.sub.1 is selected from H or C.sub.1 -C.sub.4 alkyl, comprises according to the invention the reaction of propionaldehyde with a phosphorus derivative of formula: ##STR2## in which R.sub.1 designates C.sub.1 -C.sub.4 alkyl and R.sub.2 is selected from C.sub.1 -C.sub.4 alkyl or phenyl, and, optionally, the hydrolysis of the compound of formula A in which R.sub.1 is alkyl in order to form the compounds of formula A in which R.sub.1 is H.Pharmaceutical industry.
    Type: Grant
    Filed: December 1, 1989
    Date of Patent: October 23, 1990
    Assignee: Sanofi
    Inventors: Marcel Descamps, Georges Sayac
  • Patent number: 4963743
    Abstract: In an apparatus for evaluating raw coffee beans, a near-infrared light beam is applied to sample coffee powder, a detector receives light reflected from and/or transmitted through the sample coffee powder to generate a signal representative of luminous intensity of the received light. A memory device has stored therein at least one of characteristic coefficients and appraisal coefficients for the sample coffee powder. A calculation device calculates at least one of characteristic value and appraisal values of the raw coffee beans, based on the stored coefficients and the signal from the detector.
    Type: Grant
    Filed: October 16, 1989
    Date of Patent: October 16, 1990
    Assignee: Satake Engineering Co., Ltd.
    Inventors: Toshihiko Satake, Satoru Satake, Yukio Hosaka
  • Patent number: 4962655
    Abstract: Rolling stand with rolling rings supported as a cantilever and having their axes at an angle to each other for the rolling of metallic products, the axes of the rolling rings being horizontal, vertical or tilted, the stand comprising shafts (16) to bear the rolling rings (10) with at least a first bearing (12) and a second bearing (13), at least one pair of the first and second bearings (12-13) being lodged in an eccentric support suitable to adjust the distance between centers of the rolling rings (10), the axes (15) of the rolling rings (10) coinciding with the axes (15) of the respective shafts (16), in which stand the axes (15) of the rolling rings (10) in a non-rolling condition form between them a pre-determined angle (alpha) and converge on a position outside and in front of the rolling rings (10).
    Type: Grant
    Filed: February 13, 1989
    Date of Patent: October 16, 1990
    Assignee: Danieli & C. Officine Meccaniche SpA
    Inventor: Geremia Nonini
  • Patent number: 4962948
    Abstract: In a passive seat belt system for a motor vehicle, a slide shoe mounted on a runner is composed of at least a pair of blocks spaced from each other in the direction of movement of the runner, in order to overcome the problem of the varying clearance between the runner and the guide rail. As the runner is moved along the guide rail, the two blocks contact the guide rail at their central portions and, in the meantime, an intermediate portion of the slide shoe is non-engageable with the guide rail. The result is that the slide shoe can contact the guide rail at the same portions even when the posture of the runner is changed due to the change of the curvature of the guide rail and the change of the cross-section shape of the guide rail.
    Type: Grant
    Filed: February 23, 1989
    Date of Patent: October 16, 1990
    Assignee: Nippon Seido Kabushiki Kaisha
    Inventor: Katsuyasu Ono
  • Patent number: 4963187
    Abstract: Metallizing paste is composed, by weight, of 100 parts of Pt, 0.5 to 5 parts of Ag, 0.1 to 1 part of CuO, and 2 to 10 parts of a low thermal expansion fritt, which may also contain up to 100 parts of Au. Another metallizing paste is composed, by weight, of 100 parts of Pd, 0.5 to 4 parts of Ag, 0.1 to 1 part of CuO, and 1 to 10 parts of a low thermal expansion fritt, which may also contain up to 50 parts of Au. A low thermal expansion circuit board with multi-layers is made up to a low thermal expansion substrate such as crystallized glass, A1N, SiC, Si.sub.3 N.sub.4 etc. and metallized layers formed on the surface of the substrate based on the abovementioned metallizing pastes comprising crystallized glass type materials.
    Type: Grant
    Filed: March 4, 1988
    Date of Patent: October 16, 1990
    Assignee: NGK Spark Plug Co., Ltd.
    Inventors: Kazuo Kondo, Asao Morikawa
  • Patent number: 4963418
    Abstract: A thermo-shrinkable polyester type film having the following shrinking properties:a shrinking ratio in one axis is not less than 30% at 80.degree. C. and not less than 50% at 100.degree. C., anda shrinking ratio in a perpendicular axis to the former axis shows the minimum value at a temperature range of 80.degree..+-.25.degree. C., and the process therefor.This film shows an excellent shrinking properties for packaging.
    Type: Grant
    Filed: January 26, 1989
    Date of Patent: October 16, 1990
    Assignee: Toyo Boseki Kabushiki Kaisha
    Inventors: Tsutomu Isaka, Toshihiro Yamashita
  • Patent number: 4963677
    Abstract: A compound of the formula ##STR1## and pharmaceutically acceptable salts thereof, in which A is --N.dbd.N--NH--, --X--C(R.sub.2).dbd.N--, --N.dbd.C(R.sub.2)--X--, --X--C(R.sub.2)--CH(R.sub.2).dbd.N-- or --N.dbd.C(R.sub.2)--CH(R.sub.2)--X--, wherein X is sulphur, oxygen or nitrogen and R.sub.2 is provided that where two R.sub.2 -groups are present in the A group one of the R.sub.2 groups is hydrogen, amino, substituted amino, C.sub.1-6 alkyl, substituted acylamino or one of the following groups: ##STR2## wherein R.sub.a is hydrogen, amino, substituted amino, C.sub.1-6 alkoxy, heterocyclic five membered ring or --NHCOR', wherein R' is C.sub.1-6 alkyl, aryl or heterocyclic five membered ring, R.sub.b is hydrogen, C.sub.1-6 alkoxy, C.sub.1-6 alkylthio or hydroxy, R.sub.c is hydrogen, C.sub.1-6 alkyl or oxygen and R.sub.d is C.sub.1-6 alkyl or oxygen, R.sub.e is hydrogen, hydroxy or C.sub.1-6 alkoxy, R.sub.f is C.sub.1-6 alkyl, provided that where two R.sub.2 -groups are present in the A group, one of the R.sub.
    Type: Grant
    Filed: November 8, 1988
    Date of Patent: October 16, 1990
    Assignee: Orion Corporation Ltd.
    Inventors: Lawrence Sellin, Reijo J. Backstrom, Kalevi E. Heinola, Erkki J. Honkanen, Tord K. W. Langenskiold, Irma O. Ojala, Aino K. Pippuri, Jarmo J. Pystynen
  • Patent number: 4963614
    Abstract: Primer composition for glass comprising a silane coupling agent, a reaction product of a polyisocyanate and a silane compound, a film-forming agent, and an acidic carbon black having pH 2.5 to 4. Said primer composition has extremely high weatherability and is useful as a primer for glass, particularly for applying to window glass of automobiles.
    Type: Grant
    Filed: November 27, 1989
    Date of Patent: October 16, 1990
    Assignee: Sunstar Giken Kabushiki Kaisha
    Inventors: Masahiro Ito, Shingo Tsuno
  • Patent number: 4963559
    Abstract: The present invention relates to an agent for treating cancer and preventing cancer metastasis consisting of a compound selected from 5-(2-chlorobenzyl)-4,5,6,7-tetrahydro-thieneo[3,2-c]pyridine and its therapeutically acceptable acid addition salts.The therapeutically acceptable acid addition salt is in particular the hydrochloride named Ticlopidine.
    Type: Grant
    Filed: October 27, 1982
    Date of Patent: October 16, 1990
    Assignee: Sanofi
    Inventor: Tadao Suzuki
  • Patent number: 4963626
    Abstract: A curable polymer composition which comprises (A) an oxyalkylene base polymer having at least one silicon-containing group to the silicon atom of which a hydroxyl group or a hydrolyzable group is bonded and which is cross linkable through formation of a siloxane bond and (B) at least one compound selected from the group consisting of a silicon-containing compound having at least one long chain hydrocarbon group and a silicon-containing compound having at least one fluorohydrocarbon group in an amount of 0.1 to 30 parts by weight per 100 parts by weight of the polymer (A), which composition provides a cured material having improved surface properties.
    Type: Grant
    Filed: January 19, 1989
    Date of Patent: October 16, 1990
    Assignee: Kanegafuchi Chemical Industry Co. Ltd.
    Inventors: Toshifumi Hirose, Katsuhiko Isayama
  • Patent number: 4963527
    Abstract: Complexes resulting from the reaction of phospholipids, synthetic or of vegetable or animal origin, with flavonoids extracted from Vitis vinifera, their use in therapeutics and in cosmetics.
    Type: Grant
    Filed: January 14, 1988
    Date of Patent: October 16, 1990
    Assignees: INDENA S.p.A., SANOFI
    Inventors: Ezio Bombardelli, Michel Sabadie
  • Patent number: 4963570
    Abstract: The present invention relates, by way of new industrial products, to 1-(acetylaminophenyl)-2-amino-propanone derivatives selected from the group consisting of(a) the compounds of the formulaAr--CO--CH(CH.sub.3)--NR.sub.1 R.sub.2 (I)in whichNR.sub.1 R.sub.2 represents a piperidino group; andAr represents an acetylaminophenyl group of the formula ##STR1## in which X is CH.sub.3 CONH and Y and Z, which can be identical or different, each represent a hydrogen or halogen atom; and(b) their addition salts.These new products are useful as antidepressants for the central nervous system. The invention also relates to the method for their preparation.
    Type: Grant
    Filed: July 7, 1989
    Date of Patent: October 16, 1990
    Assignee: Laboratoire L. Lafon
    Inventor: Louis Lafon
  • Patent number: 4963629
    Abstract: Copolymers of unsaturated carboxylic acids with alkaline solutions of monosaccharides or disaccharides capable of forming enolates provide polycarboxylates which are excellently suitable as sequestrants, complexing agents and co-builders in washing and cleaning agents.
    Type: Grant
    Filed: August 10, 1989
    Date of Patent: October 16, 1990
    Assignee: Grillo-Werke AG
    Inventors: Klaus Driemel, Klaus Bunthoff, Helmut Nies, Dieter Rohe
  • Patent number: 4963581
    Abstract: The present invention relates to an aromatase inhibiting composition which contains a compound of the formula: ##STR1## wherein R is hydroxy, lower alkoxy or amino which may be substituted by lower alkyl; R.sup.1 is hydrogen or lower alkyl; and A is hydrogen, a group of the formula ##STR2## in which R.sup.2 is hydroxy, lower alkoxy or amino which may be substituted by lower alkyl and R.sup.3 is hydrogen or lower alkyl, or a group of the formula ##STR3## in which R.sup.4 and R.sup.5 are independently hydrogen or lower alkyl, or a salt thereof.The present composition is useful in the prevention and treatment of estrogen-dependent diseases, such as breast cancer.
    Type: Grant
    Filed: April 5, 1989
    Date of Patent: October 16, 1990
    Assignee: Takeda Chemical Industries, Ltd.
    Inventors: Tsuneo Kanamaru, Takenori Ishimaru, Masayuki Muroi
  • Patent number: 4963680
    Abstract: A piperazine derivative of formula (I) ##STR1## in which: R is hydrogen or a straight or branched (C.sub.1 -.sub.4) alkoxycarbonyl group; andA is a 7-methoxy-1-naphthalenyl, 6-methoxy-2,3-dihydro-1-(1H)-indenyl or 7-methoxy-1,2,3,4-tetrahydro-1-naphthalenyl group, or an optically active isomer thereof, or a salt thereof.
    Type: Grant
    Filed: August 2, 1989
    Date of Patent: October 16, 1990
    Assignee: Synthelabo
    Inventors: Philippe Manoury, Jean Binet, Daniel Obitz, Gerard Defosse, Elisabeth Dewitte, Corinne Veronique
  • Patent number: 4961987
    Abstract: AlN-base sintered body with a high thermal conductivity is produced by:preparing a compact of a material comprising 100 parts by weight of aluminum nitride and 0.1-10 parts by weight, calculated on metal element, of at least one component selected from the group consisting of elements of Group 4a, 5a and 6a of the Periodic Table, and compounds thereof; andsintering said compact at a temperature ranging from 1500.degree. to 2000.degree. C. under a non-oxidizing atmosphere having a source of boron and/or carbon supply. The compounds include oxides, borides, nitrides and carbides. The elements include W, Mo, Ta and Ti. Oxides are converted to other compounds through sintering. This AlN-base sintered body has good wettability with metal for metallization and enables simultaneous sintering with metallization layer. Multilayer laminated circuit boards or substrates thereof can be produced.
    Type: Grant
    Filed: September 11, 1989
    Date of Patent: October 9, 1990
    Assignee: NGK Spark Plug Co., Ltd.
    Inventors: Akiyasu Okuno, Masakazu Watanabe, Kazuhiko Ikoma
  • Patent number: 4961922
    Abstract: A complex based on anthralin and a sterol, characterized in that its melting point is 10 to 25 degrees Celsius lower than that of the constituent of the complex melting at the lowest temperature and that the proportion of anthralin varies between 10 and 90 mol %.
    Type: Grant
    Filed: April 13, 1989
    Date of Patent: October 9, 1990
    Assignee: Centre International De Recherches Dermatolociques
    Inventors: Braham Shroot, Daniele Caron, Jean-Claude Caron, Alain Brzokewicz
  • Patent number: 4962113
    Abstract: Novel pyridinium derivatives represented by the formula (I): ##STR1## wherein ##STR2## is an optionally substituted pyridinium ring; R.sup.1 is a lower alkyl group or aralkyl group;R.sup.7 and R.sup.10 are independently hydrogen, a lower alkyl group, aryl group or aralkyl group;l is 0 or 1;R.sup.5 is a phenylene group or an alkylene group which may be substituted;R.sup.11 is an alkyl group or aryl group;X is a group of the formula: --CH.sub.2 OCH.sub.2 -- or a group of the formula: ##STR3## wherein R.sup.6 is hydrogen, a lower alkyl or a lower alkoxy, and m is an integer of 0 to 3;U is a group of the formula: ##STR4## wherein R.sup.
    Type: Grant
    Filed: July 26, 1988
    Date of Patent: October 9, 1990
    Assignee: Takeda Chemical Industries, Ltd
    Inventors: Susumu Tsushima, Muneo Takatani, Kohei Nishikawa