Patents Represented by Law Firm Wegner & Bretschneider
  • Patent number: 4962100
    Abstract: A compound of the formula: ##STR1## wherein R.sup.1 is an amino group which may be protected, R.sup.3 is a hydrogen atom or an optionally substituted hydrocarbon residue; Z is S, S.fwdarw.O, O or CH.sub.2, R.sup.4 is a hydrogen atom, methoxy group or formamido group, R.sup.13 is a hydrogen atom, methyl group, hydroxyl group or halogen atom and A.sup..sym. is an optionally substituted imidazolium-1-yl group forming a condensed ring at the 2,3- or 3,4-position or a pharmaceutically acceptable salt or ester thereof is novel and has excellent antibacterial activity.
    Type: Grant
    Filed: March 28, 1989
    Date of Patent: October 9, 1990
    Assignee: Takeda Chemical Industries, Ltd.
    Inventors: Akio Miyake, Masahiro Kondo, Masahiko Fujino
  • Patent number: 4959362
    Abstract: An ascorbic acid derivative of the formula: ##STR1## wherein R.sup.1 is organic residue having molecular weight of from 15 to 700, R.sup.2 is hydrogen or hydroxyl, R.sup.3 is hydrogen, acyl, optionally substituted phosphono or sulfo, and R.sup.3 and hydroxyl or R.sup.2 may form acetal residue or ketal residue, and a salt thereof are provided.The compound [I] and salts thereof have antioxidant activity and excellent prophylactic and improving actions on disorders of circulatory functions, and they are usefule as antioxidant agent for food and as agents of prophylaxis and improvement of circulatory functional disorders.
    Type: Grant
    Filed: September 19, 1988
    Date of Patent: September 25, 1990
    Assignee: Takeda Chemical Industries, Inc.
    Inventors: Shinji Terao, Minoru Hirata
  • Patent number: 4959316
    Abstract: The present invention relates to a process for preparing a strain of Bacillus, in the chromosome of which a specific gene has been amplified, in which process: (a) at least one plasmid integration vector bearing the said gene is integrated in the Bacillus chromosome so as to create in the chromosome: at least one DNA sequence, known as an amplifiable unit, which contains at least the said gene and its expression elements and, at each end, two sequences which are identical in the direct sense; the amplifiable unit which codes, furthermore, for a selectable gene; (b) the strains of Bacillus obtained are then selected by culture on a selection medium corresponding to the selectable gene, and the strains are withdrawn which have the phenotype corresponding to the presence of an increased number of copies of the said gene relative to the bacterial population before selection.
    Type: Grant
    Filed: December 18, 1987
    Date of Patent: September 25, 1990
    Assignee: Centre National de la Recherche Scientifique (CNRS)
    Inventors: Ehrlich Stanislas, Janniere Laurent, Pierre Evelyne, Brigitte Niaudet
  • Patent number: 4959273
    Abstract: A corrosion-resistant R-Fe-B type sintered permanent magnet exhibiting deterioration of not more than 5 % from the initial magnetic properties after being tested for 500 hours under the conditions of a temperature of 80.degree. C. and a relative humidity of 90 % is produced by:causing at least one colloidal noble metal selected from the group consisting of Pd, Ag, Pt and Au to be adsorbed in a colloidal state or forming a thin layer thereof through vapor deposition on the surface of the sintered body; applying at least one base metal selected from the group consisting of Ni, Cu, Sn and Co containing P and/or B by electroless plating; and further applying at least one base metal selected from the same group.The noble metal layer is 1-10 nm thick. The electroless plating layer is no more than 10 .mu.m and the electrolytic plating layer 5-60 .mu.m thick.
    Type: Grant
    Filed: September 18, 1989
    Date of Patent: September 25, 1990
    Assignees: Sumitomo Special Metals Co., Ltd., Toda Kogyo Corp.
    Inventors: Atsushi Hamamura, Takaki Hamada, Kouki Tokuhara, Yukimitsu Miyao, Tomoyuki Imai, Nanao Horiishi
  • Patent number: 4958573
    Abstract: Rehabilitation machine (10) for railway road beds, which comprises a framework (11) rested on a front bogie (12) and rear bogie (13), cabs (14-15) to drive the machine during its travels, an excavation chain (20) cooperating with a hopper (21) in the transfer of excavated material onto an elevator (22), and a leading end (24) and trailing end (124) relative to the direction of advance (19) of the machine (10), and also comprises at one end a first front conveyor (27) to deliver a mixture of aggregate materials (26) and a second front conveyor (33) to deliver metalling (32) towards the machine (10) and also discharge conveyors (23) to discharge excavated material from the machine (10).
    Type: Grant
    Filed: July 18, 1988
    Date of Patent: September 25, 1990
    Assignees: Danieli & C. Officine Meccaniche S.p.A., ITI/CLM Impianti Tecnici Industriali S.p.A.
    Inventor: Flavio Mancini
  • Patent number: 4957481
    Abstract: The present invention is directed toward methods for the reduction of the severity of symptoms resulting from tumors, such as pain induced by the pressure exerted on a nerve by the tumor mass. Additionally, methods for the reduction of tumor size are also contemplated.
    Type: Grant
    Filed: July 3, 1989
    Date of Patent: September 18, 1990
    Assignee: U.S. Bioscience
    Inventor: Robert A. Gatenby
  • Patent number: 4957667
    Abstract: A method of making a positive model of a tooth or gum including the steps of pouring hardenable positive impression material into a negative impression of the tooth or gum comprising a cured, vinyl polysiloxane composition, and hardening the positive impression material, and further including applying finely divided palladium over at least part of the surface of the negative impression that will contact the positive impression material before pouring the hardenable positive impression material.
    Type: Grant
    Filed: November 7, 1988
    Date of Patent: September 18, 1990
    Assignee: Minnesota Mining and Manufacturing Company
    Inventor: James D. Hamer
  • Patent number: 4957991
    Abstract: A chloroprene copolymer produced by radical copolymerization of 50 to 95% of chloroprene, 5 to 50% of at least one polyether (meth)acrylate of a specific formula, and 0 to 10% of any monomer copolymerizable with chloroprene, these percentages being by weight and based on the total quantity of monomers copolymerized, exhibits a remarkable combination of excellent oil resistance, weathering resistance, heat resistance, and coldness resistance. It was found that even when a polyether molecular chain has poor compatibility with chloroprene rubber, if this chain has an acryloyl or a methacryloyl group at one or both ends thereof, it can be copolymerized with chloroprene, and the resulting chloroprene copolymer processes and above mentioned combination of excellent properties.
    Type: Grant
    Filed: December 1, 1986
    Date of Patent: September 18, 1990
    Assignee: Denki Kagaku Kogyo KK
    Inventors: Nobuhiro Hirashima, Shiro Matsunaga, Mitsuyuki Nakata
  • Patent number: 4957980
    Abstract: A polyester resin composition having excellent gas barrier properties and transparency which comprises 100 parts by weight of a thermoplastic polyester resin (A), 1 to 100 parts by weight of a polyamide resin having metaxylylene group (B) and 0.01 to 50 parts by weight of a compatibilizing agent (C); and a polyester hollow molded article in the form of a single or multi-layered hollow molded article, wherein at least one of the layers is made of the above polyester resin composition.
    Type: Grant
    Filed: August 8, 1988
    Date of Patent: September 18, 1990
    Assignee: Toyo Boseki Kabushiki Kaisha
    Inventors: Shigeo Kobayashi, Toshio Hiramatsu, Katsumasa Yamamoto, Nobuhiko Ichikawa
  • Patent number: 4956958
    Abstract: An autofitting building block has two opposing side surfaces, two opposing end surfaces, a top surface and a bottom surface. The top surface has a plurality of dihedral projections which mate with a plurality of dihedral recessions on the bottom surface. The bottom surface has at least one more recession than does the top surface so that a channel is formed between two stacked bricks. Grooves are preferably placed in the end walls which form vertical channels which communicate with the hozizontal passages. A wall made of such bricks is also disclosed. The blocks can be either solid or hollow, and special blocks can be used for the corners and for the ends of the wall.
    Type: Grant
    Filed: February 15, 1989
    Date of Patent: September 18, 1990
    Inventor: Gino P. N. Caroti
  • Patent number: 4957625
    Abstract: An apparatus for filtering a liquid, includes supplying a starting liquid from a container to a passage of a pipe-like filter set in a filter casing, passing the starting liquid through the passage of the filter thereby to produce the filtrate, sending back the unfiltered liquid to the container, and back washing the filter by means of a hydraulic pressure device having a piston movable in a cylinder in such a manner that the filtrate is moved by the piston of the hydraulic device.
    Type: Grant
    Filed: April 27, 1989
    Date of Patent: September 18, 1990
    Assignee: Toshiba Ceramics Co. Ltd.
    Inventors: Yoshihisa Katoh, Takashi Ogawa, Mitsumasa Hasegawa, Masashi Fujimoto, Masaaki Hayashi
  • Patent number: 4957906
    Abstract: Disclosed is a pharmaceutical composition containing an aminobenzoic acid derivative as an active ingredient represented by the following general formula: ##STR1## wherein .sup.1 R donotes one member selected from the group consisting of the residual groups formed by removing OH at 1(alpha) or 1(beta) position from arabinose, glucose, galactose and mannose, or a pharmaceutically acceptable salt thereof.
    Type: Grant
    Filed: February 26, 1988
    Date of Patent: September 18, 1990
    Assignee: Kureha Kagaku Kogyo Kabushiki Kaisha
    Inventors: Chikao Yoshikumi, Yoshio Ohmura, Fumio Hirose, Masanori Ikuzawa, Kenichi Matsunaga, Takayoshi Fujii, Minoru Ohhara, Takao Ando
  • Patent number: 4956209
    Abstract: An anti-fogging multilayered film suitable for packaging fresh vegetables and fruits comprising a base layer and at least one surface layer containing an anti-fogging agent, said film having a water vapor transmission of 15 to 200 g/m.sup.2 .multidot.24 hr.multidot.40.degree. C., an oxygen permeability of 3,000 to 35,000 cc/m.sup.2 .multidot.24 hr.multidot.atm.multidot.20.degree. C..multidot.90% RH, and a carbon dioxide permeability of 12,000 to 130,000 cc/m.sup.2 .multidot.24hr.multidot.atm.multidot.20.degree. C..multidot.90% RH, and said anti-fogging surface layer having heat sealing properties. A packaging bag produced from this film is also disclosed.
    Type: Grant
    Filed: March 21, 1989
    Date of Patent: September 11, 1990
    Assignee: Toyo Boseki Kabushiki Kaisha
    Inventors: Tsutomu Isaka, Saburo Ohta
  • Patent number: 4956731
    Abstract: A tape feeding direction controlling device for an automatic reversing tape recorder wherein operation of a first or a second high speed operating member during a reproducing operation will cause high speed feeding of a tape in the same or in the opposite direction. The tape feeding direction controlling device comprises a feeding direction controlling member, a high speed change-over member, and a pivotal member connected to be bodily moved by the feeding direction controlling member. Depending upon whether the pivotal member is at its first or second position, it is pivoted in opposite directions by the first or second high speed operating member, and pivotal motion of the pivotal member in one or the other direction moves the high speed change-over member from its neutral position to a first or a second position in which it causes a tape feeding mechanism to feed a tape at a high speed in one or the other direction.
    Type: Grant
    Filed: March 20, 1989
    Date of Patent: September 11, 1990
    Assignee: Tanashin Denki Co., Ltd.
    Inventor: Toshio Yoshimura
  • Patent number: 4955898
    Abstract: A surgical staple has a base portion and a pair of leg portions respectively extending angularly from the opposite ends of the base portion. Each leg portion has at its distal end portion a first inclined surface and a second inclined surface extending from the first inclined surface to the distal end of said leg portion. The first and second inclined surfaces are inclined with respect to the axis of the leg portion. The angle between the first inclined surface and the axis of the leg portion is smaller than the angle between the second inclined surface and the axis of the leg portion. The second inclined surface terminates in a sharp edge at its distal end. For producing the surgical staple, a blade is moved toward each of the leg portions in inclined relation to the axis thereof to shear the leg portion, so that a smooth sheared surface and a coarse ruptured surface are formed on the distal end portion of the leg portion and arranged in this order toward the distal end of the leg portion.
    Type: Grant
    Filed: October 30, 1989
    Date of Patent: September 11, 1990
    Assignee: Matsutani Seisakusho Co., Ltd.
    Inventors: Kanji Matsutani, Masatoshi Fukuda
  • Patent number: 4956491
    Abstract: A polymer comprising a carbon-carbon backbone chain and at least one N-(substituted oxalyl)carbamoyl group of the formula: --CO--NH--CO--CO--OR' wherein R' is a hydrocarbon group and at least one lower alkyl group attached to said chain, which is useful as a resin component in a coating, adhesive or molding composition.
    Type: Grant
    Filed: April 27, 1987
    Date of Patent: September 11, 1990
    Assignee: Nippon Paint Co., Ltd.
    Inventors: Yuji Suzuki, Satoshi Urano, Hirotoshi Umemoto, Ryuzo Mizuguchi, Kei Aoki, Noriyuki Tsuboniwa
  • Patent number: 4956459
    Abstract: Compounds of the formula: ##STR1## wherein each of R.sub.1 and R.sub.2 is independently selected from the group consisting of halogen, hydroxy, or mono carboxylic acid or R.sub.1 and R.sub.2 together is a multifunctional carboxylic acid residue which forms a ring with the platinum atom through two oxygens of said multifunctional carboxylic acid; R.sub.3 is a deoxy mono or disaccharide or a derivative thereof; and R.sub.4 is selected from the group consisting of hydrogen, C.sub.1-4 -alkyl, phenyl, benzyl, substituted phenyl or substituted benzyl, wherein substituents are selected from the group consisting of halogen, nitro, C.sub.1-2 -alkoxy, carboxy, carbony ester or phenyl or a pharmaceutically acceptable salt thereof are disclosed. Compositions containing these compounds and methods using these compounds are also discussed.
    Type: Grant
    Filed: January 14, 1988
    Date of Patent: September 11, 1990
    Assignee: Georgetown University
    Inventors: Abdolhossen Talebian, Dianna C. Green, Charles F. Hammer, Philip S. Schein
  • Patent number: 4956431
    Abstract: A novel mildew resistant polymerizable compound of the formula: ##STR1## wherein X is --O-- or --S--; and Y is a residue of a known mildew proofing compound, preferably, a residue of a compound selected from the group consisting of phenol substituted with 1 to 5 halogen atoms, p-chloro-m-cresol, o-phenylphenol, p-chloro-m-xylenol, salicylanilide, 8-hydroxyquinoline, 2-(4'-thiazolyl)benzimidazole, 2,5-dibromo-4-methylaniline, 1,2-benzoisothiazolin-3-one and 2-pyridinethiol-1-oxide. A polymer of the compound [I] and a polyurethane composition containing the polymer are also disclosed.
    Type: Grant
    Filed: November 9, 1988
    Date of Patent: September 11, 1990
    Assignee: Toyo Boseki Kabushiki Kaisha
    Inventors: Hideyuki Mitamura, Yoshikazu Arimatsu
  • Patent number: 4956317
    Abstract: Whisker-reinforced ceramics with high fracture toughness and strength consists essentially of 5-40 weight % SiC including SiC whiskers, 1-30 weight % of at least one kind of oxides of elements selected from the group consisting of Al, Sc, Y and rare-earth elements, and the balance being silicon oxynitride constituents, wherein said SiC whiskers are present in an amount of no less than 5 weight % of the total essential constituents.The silicon oxynitride constituents are Si.sub.2 N.sub.2 O or a mixture of silicon nitride and silica (0.83-1.22 by molar ratio), or a mixture of Si.sub.2 N.sub.2 O and said mixture of silicon nitride and silica. Silicon oxynitride and SiC phases are predominant.
    Type: Grant
    Filed: November 29, 1988
    Date of Patent: September 11, 1990
    Assignee: NGK Spark Plug Co., Ltd.
    Inventors: Hitoshi Yokoi, Masakazu Watanabe, Akiyasu Okuno, Satoshi Iio
  • Patent number: 4956358
    Abstract: The compounds having a 4,11-dioxo-3-oxa-8(or 7)-thia-1-azatricyclo[7,2,0,0.sup.2,6 ]undecane-2-carboxylic acid skeleton as the base structures, their esters and their salts are useful antibacterial agents.
    Type: Grant
    Filed: July 10, 1987
    Date of Patent: September 11, 1990
    Assignee: Takeda Chemical Industries, Ltd.
    Inventors: Akira Morimoto, Noriyoshi Noguchi, Nobuo Choh