Abstract: A network with a set of servers can support authentication from a module, where the module includes an embedded universal integrated circuit card (eUICC). The network can send a first network module identity, a first key K, and an encrypted second key K for an eUICC profile to an eUICC subscription manager. The second key K can be encrypted with a symmetric key. The module can receive and activate the eUICC profile, and the network can authenticate the module using the first network module identity and the first key K. The network can (i) authenticate the user of the module using a second factor, and then (ii) send the symmetric key to the module. The module can decrypt the encrypted second key K using the symmetric key. The network can authenticate the module using the second key K. The module can comprise a mobile phone.

Abstract: A novel and useful system and method of generating quantum unitary noise using silicon based quantum dot arrays. Unitary noise is derived from a probability of detecting a particle within a quantum dot array structure comprising position based charge qubits with two time independent basis states |0> and |1>. A two level electron tunneling device such as an interface device, qubit or other quantum structure is used to generate quantum noise. The electron tunneling device includes a reservoir of particles, a quantum dot, and a barrier that is used to control tunneling between the reservoir and the quantum dot. A detector circuit connected to the device outputs a digital stream corresponding to the probability of a particle of being detected. Controlling the bias applied to the barrier controls the probability of detection. Thus, the probability density function (PDF) of the output unitary noise can be controlled to correspond to a desired probability.

Abstract: The invention relates generally to wearable accessory carriers for mechanical circulatory support systems, and more specifically relates to belts for carrying peripheral components of a VAD. Such wearable accessory carriers may be suitable for carrying and retaining peripheral components of the VAD in a safe, comfortable, and convenient manner. In certain aspects, the invention provides a wearable accessory carrier configured as an elastic belt with several pockets for holding peripheral components. In other aspects, a wearable accessory carrier may be configured as a belt with a magnetic strip configured to carry one or more modular compartments or pockets for holding peripheral components via magnetic attachment. The wearable accessory carriers disclosed herein may be sized to fit around or configured to be worn on a patient's waist, lower or upper torso, thigh, calf, arm, or other limb.

Abstract: A system for populating web-based form and managing e-commerce checkout process is disclosed. Combined with the data mapping to user profile, the checkout workflow should be able to make all of the necessary calls on behalf of the user to perform checkout completely. The system performs user authentication to ensure that the user profile is accessed only by the authorized user. During run-time, the program adds the product to cart, and load the checkout pages on behalf of the user, remembers the states such as the cookies and CSRF tokens and performs the form filling using their user profile data. The system makes one or more server calls to the e-commerce website from at least one of the servers or a browser in one click based on filled we-based form to complete a checkout process.

Abstract: A method of obtaining 3D cell structures including differentiated human hepatic cells. The method includes: a first step of culturing stem cell-derived or immortalized human hepatic progenitors in a non-adherent culture vessel, preferably a low or ultra-low attachment culture vessel; a second step of transferring the stem cell-derived or immortalized human hepatic progenitors to a culture medium including methacrylated gelatin (GelMa), thereby embedding the stem cell-derived or immortalized human hepatic progenitors in a GelMa matrix; and a third step of covering the GelMa matrix with culture medium and culturing the stem cell-derived or immortalized human hepatic progenitors embedded in the GelMa matrix, thereby obtaining 3D cell structures including differentiated human hepatic cells. Also, methods for engineering an artificial liver model or an artificial liver organ, and for assessing in vitro the metabolism, toxicity and/or therapeutic effects of a compound.

Abstract: Hydrogen generation assemblies and methods are disclosed. In one embodiment, the method includes receiving a feed stream in a fuel processing assembly, and heating, via one or more burners, a hydrogen generating region of the fuel processing assembly to at least a minimum hydrogen-producing temperature. The method additionally includes generating an output stream in the heated hydrogen generating region of the fuel processing assembly from the received feed stream, and generating a product hydrogen stream and a byproduct stream in a purification region of the fuel processing assembly from the output stream. The method further includes separating at least a portion of the carbon dioxide gas from the byproduct stream to generate a fuel stream having a carbon dioxide concentration less than the byproduct stream, and feeding the fuel stream to the one or more burners.

Abstract: A technology is provided for invoking a random linear network coding (RLNC) communications protocol between a client and server in a network. In one example, a synchronize message requesting a network connection to a server can contain an indication that a client supports the RLNC communications protocol to encode and decode data packets using random linear network coding. The server can analyze the synchronize message for the indication that the client supports the RLNC communications protocol and send an acknowledge message to the client indicating that the server supports the RLNC communications protocol. Thereafter, the server can listen on a communications channel for a connection request sent by the client to communicate with the server using the RLNC communications protocol.

Abstract: The present invention relates to a method of treatment and method of therapy selection for patient suffering from cancer. The inventors provide the first demonstration of a dual role of IRE1 downstream signaling in cancer. Indeed, the inventors demonstrate that the modulation of IRE1 signaling characteristics in GBM cells controls tumor aggressiveness. Furthermore, the inventors provide evidence supporting a novel concept where IRE-downstream signals play combined/integrated roles in cancer development, where XBP1s provides pro-tumoral signals, whereas RIDD of mRNA and miR17 rather elicits anti-tumoral features. Their data, obtained using established cell lines, patient tumor samples and primary GBM lines, depict a complex scenario where IRE1 signaling orchestrates distinct aspects of GBM biology. In particular, the invention relates to a method for predicting whether a subject will be eligible to a treatment with an IRE1 RNase inhibitor.

Abstract: The invention relates a fluorescent compound of formula I: wherein A is selected from P, P?O and N; ·R1 is a residue comprising an oxygen atom·R2 is a residue comprising an oxygen atom, or a halogen, ·R3, R4 and R5 are alkyls, possibly substituted or a salt or a solvate thereof. The compound is useful as a fluorescent probe sensitive to membrane fluidity and for diagnosing cancer.

Abstract: The present invention is generally related to methods and systems for preventing onset or worsening of RHF in patients with implanted ventricular assist devices. More particularly, the present invention relates to identifying patients at risk for RHF following implantation of a ventricular assist device based on pulmonary artery pressure measurement and/or trends and adjusting a pump operating parameter to prevent or reduce the onset or worsening of RHF in such patients, improve patient outcomes, or reduce mortality risks associated with VAD implantation. In particular, a pump operating parameter may be adjusted to reduce or minimize particularly high pressure loads on a patient's heart or amount of time the patient is exposed to such high pressure loads following implantation.

Abstract: Provided is a picture encoding device that divides a picture into blocks and performs encoding for each of the divided blocks. A primary signal block divider divides a primary signal of the picture into rectangles having a predetermined size, and generates a primary signal block. A secondary signal block divider divides a secondary signal of the picture into rectangles having a predetermined size, and generates a secondary signal block. A primary signal predictor predicts a primary signal, and a secondary signal predictor predicts a secondary signal. The secondary signal predictor can perform inter prediction of predicting a secondary signal from an encoded primary signal, and the inter prediction is restricted based on at least one of a size of the primary signal block and a size of the secondary signal block.

Abstract: The probiotic composition comprises at least one lactic acid bacteria strain, preferably Lactobacillus with intestinal tropism, for use in promoting juvenile growth in livestock, with stimulation of linear growth and/or of IGF-1 level. Exemplary lactic acid bacteria include Lactobacillus plantarum, Lactobacillus fermentum, Lactobacillus casei, Lactobacillus paracasei and Lactobacillus rhamnosus. The strains can be selected in a mouse model. The invention also relates to a probiotic treatment method using this composition.

Abstract: An in vitro or ex vivo method for determining the ability of an individual to respond to a stimulus, based on the measurement of the expression of at least two different biomarkers, selected from different lists among three lists of biomarkers, from a blood sample of the individual, incubated with the stimulus, as well as tools allowing the implementation of this method and the use of these tools.

Abstract: Systems and related methods for supplying power to a medical device employ serially-connectable portable batteries. A method of supplying electrical power to a medical device includes discharging a first external battery to output electrical power to a second external battery. Distribution of the electrical power received by the second external battery is controlled to simultaneously charge the second external battery and output electrical power from the second external battery to supply electrical power to the medical device.

Abstract: The present invention relates to a process for synthesizing hydroperoxy alcohols by perhydrolysis of epoxides, using an aqueous solution of hydrogen peroxide, in the presence of a catalyst consisting of phosphotungstic acid.

Abstract: The present invention relates to a pharmaceutical or veterinary composition for its use in preventing and/or treating a MERS-CoV (Middle-East Respiratory Syndrome) coronavirus infection, characterised in that it comprises, in a suitable pharmaceutical vehicle, at least one compound chosen from apigenin and berberine.

Abstract: A multi-layer identification patch includes a reflective background layer comprising a front side to face away from a garment when the multi-layer identification patch is affixed to the garment, and a mask layer secured over the front side of the reflective background layer. The mask layer comprises (a) an opaque layer of flexible polyvinyl chloride (PVC) and (b) a void in the opaque layer of flexible PVC. The void has a shape that forms an identification symbol. The opaque layer of flexible PVC is secured over a first portion of the reflective background layer, thereby fixing the void that forms the identification symbol over a second portion of the reflective background layer, and thereby enabling the second portion of the reflective background layer to reflect light through the void in the shape of the identification symbol. Other embodiments are described and claimed.

Abstract: A molded container of solid continuous construction having a floor and contiguous upstanding sidewalls angling outward and upward to a surrounding upper lip. Below the upper lip the floor and sidewalls surround an inner cavity adapted to receive food. The sidewalls include at least three outwardly-directed lugs that are thicker from an inner surface to an outer surface thereof than a nominal wall thickness of the remainder of the sidewalls. The sidewall at the location of each lug having an inner surface which is contiguous and uninterrupted relative to the inner surface of adjacent portions of the sidewall. Consequently, a first container may be stacked and nested within a second container such that the lugs on the first container contact the inner surface of the second container at the location of the lugs on the second container and maintain a predetermined axial spacing between the first and second containers.

Abstract: The invention generally relates to improved medical blood pump devices, systems, and methods. For example, blood pumps may be provided that include a housing defining a blood flow path between an inlet and an outlet. A rotor may be positioned in the blood flow path. A motor stator may be driven to rotate the rotor to provide the blood flow through the pump. Axial and/or tilt stabilization components may be provided to increase an axial and/or tilt stabilization of the rotor within the blood flow path. In some embodiments, biasing forces are provided that urge the rotor toward a bearing component. The biasing force may be provided by adjusting drive signals of the motor stator. Additionally, or alternatively, one or more magnets (e.g., permanent/stator magnets) may be provided to bias the rotor in the upstream and/or downstream direction (e.g., toward a bearing (chamfer, step, conical), or the like).

Abstract: The invention relates to a method for synthesizing ultrasmall silica nanoparticles, useful in particular for diagnostics and/or therapy. More specifically, a method for synthesizing silica nanoparticles, said method comprising the mixing of at least one silane which is negatively charged at physiological pH with at least one silane which is neutral at physiological pH, and/or at least one silane which is positively charged at physiological pH, wherein: —the molar ratio A of neutral silane(s) to negatively charged silane(s) is defined as follows: 0?A?6, —the molar ratio B of positively charged silane(s) to negatively charged silane(s) is defined as follows: 0?B?5, —the molar ratio C of neutral and positively charged silanes to negatively charged silane(s) is defined as follows: 0<C?8. The invention also relates to the obtained ultrasmall silica nanoparticles.