Abstract: The present invention relates to a system and assembly for refilling a reservoir with liquid dispensed from a dispenser, in particular, but not exclusively, to a system and assembly for the substantially leak-free refilling of the reservoir of a smoking-substitute device with a liquid comprising nicotine from a refill dispenser. The assembly is configured to provide a gas communication pathway through the assembly and physically separate from the liquid communication pathway for venting gas from an end of the assembly proximal the first aperture to an exterior of the assembly responsive to the movement of the assembly to the secured and open configuration, the assembly configured to close the gas communication pathway in the unsecured and closed configuration.

Abstract: An optical apparatus includes a substrate that is configured to redirect a predetermined percentage of an input light beam at a plurality of angles to form a set of output beams at each of the angles such that light beams redirected at each of the angles cooperate to form bands of light at a range of predetermined distances from the optical apparatus.

Abstract: Hydrogen purification devices and their components are disclosed. In some embodiments, the devices may include at least one foil-microscreen assembly disposed between and secured to first and second end frames. The at least one foil-microscreen assembly may include at least one hydrogen-selective membrane and at least one microscreen structure including a non-porous planar sheet having a plurality of apertures forming a plurality of fluid passages. The planar sheet may include generally opposed planar surfaces configured to provide support to the permeate side. The plurality of fluid passages may extend between the opposed surfaces. The at least one hydrogen-selective membrane may be metallurgically bonded to the at least one microscreen structure. In some embodiments, the devices may include a permeate frame having at least one membrane support structure that spans at least a substantial portion of an open region and that is configured to support at least one foil-microscreen assembly.

Abstract: A dynamic output power management unit for a heating circuit of an electronic smoking device is disclosed, the heating circuit having a heating element connected to a power source via a first switching element, the unit having at least one voltage detection device to detect voltage values at various points of the heating circuit; and a controller configured to deriving a resistance of the heating element, estimating a discharge time or a power consumption value of the power source such that an energy converted in a period of time is substantially identical to a predetermined energy conversion value for a same period of time.

Abstract: A multilayer scintillation detector, includes at least three layers superposed on one another, and each extending parallel to a plane, called the detection plane, wherein each layer is formed by a first material, called a scintillation material, capable of interacting with an ionizing radiation and of forming, following the interaction, a scintillation light in a scintillation spectral band; each layer has a plurality of light guides, respectively extending parallel to the detection plane, according to a length, the light guides being disposed, over all or part of their length, parallel to an axis of orientation; the axis of orientation of the light guides of each layer is oriented, in the detection plane, according to an orientation, the orientations of the respective axes of orientation of at least three layers being different from one another, such that each layer has an associated orientation; and the scintillation material has a first refractive index.

Abstract: The present disclosure relates to 2,6-diaminopurine (DAP) for use in the treatment of a disease caused by a nonsense mutation in a gene, leading to the premature insertion of a UGA stop codon.

Abstract: The present invention provides antibodies directed against ICOS or a derivative thereof which neutralize ICOS engagement on Treg by inhibiting the fixation between ICOS and ICOS-L and abrogate proliferation of Treg induced by plasmacytoid dendritic cells. The present invention further provides antibodies directed against ICOS or a derivative thereof which induce IL-10 and IFN? production, induce CD4? T cells proliferation, reduce Tconv proliferation, and increase the immunosuppressive function of Treg.

Abstract: A chair, in particular an office chair, has a seat inclination mechanism. A transverse strut of the seat inclination mechanism forms a spring device and this spring device has at least one torsion element. The seat inclination mechanism further has a basic support on which a backrest support and a seat element support are articulated. The transverse strut of the seat inclination mechanism forms a spring device. The transverse strut extends in the chair transverse direction and wherein the spring device has at least one torsion element, in particular a torsion bar spring. The torsion element, together with the basic support and/or the backrest support and/or the seat element support, is formed integrally, in particular in one piece, from plastic.

Abstract: In one embodiment, a method for producing coke that includes mixing at least a first and a second carbonaceous material into a single feedstock of carbonaceous material. The coking feasibility of the single feedstock of carbonaceous material is then determined. The single feedstock is customized into a predetermined material composition, and then the customized single feedstock is pyrolyzed to produce coke material and coke by-products. Other embodiments are also disclosed.

Abstract: An electronic cigarette includes a battery assembly, an atomizer assembly and a cigarette bottle assembly. An external thread electrode is located in one end of battery assembly. An internal thread electrode is located in one end of atomizer assembly. The battery assembly and the atomizer assembly are connected by the screwthread electrode. The cigarette bottle assembly is inserted into the other end of the atomizer assembly and both form a cigarette type or cigar type body.

Abstract: This method for acquiring a spatial map of auditory perception of a subject comprises a plurality of successive test sequences, each test sequence comprising steps of: a) calibration (1002) of the subject's position, by displaying instructions to the subject, using a head-mounted visual display system worn by the subject, in order to acquire a reference position of the subject, the subject's position being measured using a video motion capture system by measuring the spatial coordinates of a first optical marker worn by the subject, b) choosing (1004) spatial coordinates of a target location of a sound source, said target cation being located around the subject, c) emitting (1006) a predefined sound, using a sound source placed at said target location, d) in response to acquisition instructions generated by the subject using an acquisition interface, acquiring (1008) an estimated location of said sound source, by using the video motion capture system to measure the spatial coordinates of a second optical mark

Abstract: A shielding element comprises a rigid substrate and at least one electrically conductive two-dimensional structure which is placed on one of the faces of the substrate. The substrate and the electrically conductive two-dimensional structure are such that the shielding element has optical-transmission and shielding-efficiency values at least one of which varies between two zones of the shielding element. Such a shielding element enables easier assembly of a detection system comprising multiple optical sensors.

Abstract: A sleeve for a cam phaser, wherein the sleeve is arranged between a central valve and a rotor of the cam phaser, wherein the rotor is rotatable relative to a stator of the cam phaser about a rotation axis of the rotor, wherein a vane of the rotor is arranged positionable between two bars of the stator, wherein the vane divides an intermediary space that is formed between the two bars into a first pressure chamber and a second pressure chamber, wherein the rotor is movable by pressures that are provided in the first pressure chamber and in the second pressure chamber, wherein the central valve is configured to provide pressure loading and pressure relief of the first pressure chamber and the second pressure chamber.

Abstract: A hydraulic valve including a valve housing; and a valve piston that is axially movable in the valve housing along a first longitudinal axis of the valve housing, wherein the valve housing includes a supply connection for feeding a hydraulic fluid, at least one operating connection and at least one tank connection for draining the hydraulic fluid, wherein the valve piston is movable by an electromagnetic actuator of the hydraulic valve, wherein the valve housing forms a hydraulic portion and the actuator forms a magnet portion of the hydraulic valve, wherein a divider element is arranged between the hydraulic portion and the magnet portion, and wherein the divider element is configured to provide a flow connection between the hydraulic portion and the magnet portion and vice versa.

Abstract: Facilitating dynamic satellite and mobility convergence for mobility backhaul in advanced networks (e.g., 4G, 5G, 6G and beyond) is provided herein. Operations of a system can comprise determining that a group of user equipment devices are located in a defined geographic area and are consuming more than a defined level of resources of a wireless communications network based on an amount of network traffic received from the group of user equipment devices. The operations also can comprise configuring an integrated network comprising a first group of terrestrial network devices and a second group of satellite network devices. Further, the operations can comprise routing at least a portion of network traffic associated with the group of user equipment devices among the first group of terrestrial network devices and the second group of satellite network devices.

Abstract: A process for preparing a polyaminoborane comprising reacting at least one monomer with an aminoborane, wherein the at least one monomer is selected from the group consisting of ammonia, a primary amine and a substituted or unsubstituted hydrazine; and wherein the aminoborane comprises a borane substituted by a secondary amino group; polyaminoboranes obtainable by said process; use of said polyaminoboranes for the preparation of a ceramic precursor or a ceramic, the production of boron nitride, or the storage and/or production of dihydrogen; ceramic precursors, ceramics, hydrogen cells or energy materials comprising said polyaminoboranes.

Abstract: Provided is a process for preparing the compound 3 (3) or a salt or a solvate thereof, the process comprising the steps of a) Mixing the compound 4 with a mineral acid (4); b) Adding a nitrite salt or an organic nitrite derivative to the reaction mass to form a diazonium salt; c) Adding a sulfur-containing reducing agent to the reaction mass to form a hydrazyl sulfur complex, such as a hydrazyl sulfite complex; d) Hydrolysing the hydrazyl sulfur complex to provide the compound 3 or a salt or solvate thereof; and e) Optionally isolating the compound 3 or a salt or solvate thereof. Further provided is the use of the compound 3 in the synthesis of 3-[5 -Amino-4-(3-Cyanobenzoyl)-Pyrazol-1-yl]-N-Cyclopropyl-4-Methylbenzamide.

Abstract: A method, system, and medium are provided for distributing transportation alerts to computing devices in accordance with factors, such as device-specific and location-specific factors. In embodiments of the present invention, travel alerts, including public alerts associated with certain areas, are formatted or held prior to delivery, based on safety concerns, legal requirements, device settings, or other considerations.

Abstract: The invention relates to a drive device for activating a rotary slide for a fluid system of an at least in part electrically operated motor vehicle. The drive device comprises an electric motor having a motor output shaft, a rotary slide output shaft configured for activating a rotary slide, wherein the rotary slide output shaft is aligned so as to be orthogonal to the motor output shaft, and a magnet is disposed on an end region of the rotary slide output shaft, and a sensor unit which is configured for detecting a rotary position of the magnet and thus of the rotary slide output shaft.