Abstract: The invention provides a method and an apparatus for winding material. The apparatus includes first and second roll carriages that are each configured to support a roll shaft. At least one of the first and second roll carriages is configured to be rotated by a drive member. The apparatus also includes an engagement roller displaceable from a first engagement roller position where the traveling roller is free of a web to a second, different engagement roller position where the traveling roller is configured to engage the periphery of a roll of web material that is at least partially wound about the roll, a traveling roller displaceable from a first traveling roller position to a second traveling roller position and a cutter where the cutter is configured to cut through the web after the first roll carriage moves from a first roll carriage position to a second roll carriage position.

Abstract: Axial flow demisting cyclone for separation of a mixture of gas and liquid including an inlet 30 for gas containing liquid droplets and an outlet 31 for substantially dry gas, including a mainly cylindrical cyclone tube 16 with at least one path of slots or perforations 19 allowing a part of the fluid, including separated liquid, to flow out of the cyclone tube 16. The demisting cyclone also includes a swirl inducing device 17, 18 to set the entering fluid in rotation. This swirl-inducing device is formed from a cascade of vanes 18 attached to a concentric core body 17, preferably cylindrical in shape, which extends towards the wall of the cyclone tube 16, the vanes 18 being in the longitudinal direction of the vanes from their leading edge 23 to their trailing edge 24.

Abstract: A method and an apparatus for manufacturing a multi-layer fabric including at least one fibre layer formed by airlaying combined with at least one further layer which is formed by different technologies, including carding, spunlacing, meitblowing, spunbonding, or airlaying, or combined with one or more films. The airforming is performed on a separate formerwire which is applied vacuum via a suction box disposed opposite to a formerhead, and where the airformed fibre layer is transferred to a conveyor wire for joining with a further layer. Edge trimming is performed at least on the airformed layer before it is joined with one or more other layers for forming the multi-layered fabric. Scrap from edge trimming and exhaust from the suction box is returned to the formerhead.

Abstract: Use of compounds to inhibit hormone-sensitive lipase, pharmaceutical compositions comprising the compounds, methods of treatment employing these compounds and compositions, and novel compounds. The present compounds are inhibitors of hormone-sensitive lipase and may be useful in the treatment and/or prevention of medical disorders where a decreased activity of hormone-sensitive lipase is desirable.

Abstract: The need for the delivery of insulin by injection can be reduced or eliminated by delivering aerosolized insulin. Repeatability of dosing is obtainable by using either regular insulin or monomeric insulin. When delivering insulin (not monomeric) by inhalation, the total inhaled volume should be about the same at each delivery to obtain repeatable results. The patient can be coached (by teaching) to inhale a given amount of air and can also be coached (by teaching) to inhale at a given flow rate. Further, the rate at which blood glucose is lowered is increased by the use of monomeric insulin. Particles of insulin and monomeric insulin delivered to the surface of lung tissue will be absorbed into the circulatory system. A dry powder or a liquid insulin formulation is delivered to the patient from a mechanical or electronic hand-held, self-contained device.

Abstract: The present invention relates to nucleic acids encoding polypeptides having glucanotrans-ferase activity, nucleic acid constructs, recombinant expression vectors, recombinant host cells and methods for producing polypeptides having glucanotransferase activity.

Abstract: This invention relates to a hearing aid system (100, 200, 300) for generating auditory spatial cues. The hearing aid system (100, 200, 300) comprises a first microphone unit (306) adapted to convert sound received at a first microphone (102) and received at a second microphone (104), a first delay unit (106) connected to the first microphone (102) delaying the signal from the first microphone (102), a first calculation unit (108) for summing the delayed signal of the first microphone (102) and signal of the second microphone (104), a processor unit (110) processing the summed signal, and a speaker converting the processed signal to a processed sound. The first and second microphones (102, 104) are separated by a predetermined first distance and the first delay unit (106) provides a predetermined first delay thereby generating a first auditory spatial cue representing a first spatial dimension in the summed signal.

Abstract: An expandable balloon for use in angioplasty procedures comprises a balloon having an outer surface layer, the outer surface layer being made from electrospun nanofibers and incorporating at least one pharmaceutically active substance, such as nitric oxide (NO). The outer surface layer may be formed on a separate flexible tubular member or sock, which is slipped over the balloon. A method of treating cell disorders in tubular structures of a living being comprises the steps of placing a coated balloon at a treatment site within the tubular structures, expanding the balloon at the treatment site, and releasing the pharmaceutically active substance at the treatment site. Optionally, a stent may be crimped onto the balloon prior to insertion of the balloon and scent into the tubular structures of the living being.

Abstract: The present invention relates to a liquid composition comprising an enzyme and an enzyme stabilizer of the following formula: or a salt thereof, wherein R1 is selected from the group consisting of C0-C5 alkyl, substituted C1-C5 alkyl, C1-C5 alkenyl and substituted C1-C6 akenyl and R2, R3, R4, R5 and R6 is selected from the group consisting of hydrogen, C1-C6 alkyl, substituted C1 to C6 alkyl, aryl, substituted aryl, hydroxyl, hydroxyl derivative, amine, C1-C6 alkylated amine, amine derivative, halogen, nitro, thiol, thiol derivative, aldehyde, acid, acid salt, ester, sulfonate or phosphonate.

Abstract: A method of applying and evenly distributing a quantity of particulate material such as ground or dried coffee within a shallow tray (22), comprises the steps of providing the quantity, delivering the quantity within the tray, the tray having a plurality of pins (40) to be positioned within the particulate material while vibrating the tray, vibrating the tray horizontally at a low vibrational frequency and for a specific period of time for causing the particulate material to be evenly distributed within the tray, transferring the quantity from the tray to a further processing station such as a freezing station or a drying station. The quantity is provided from an overhead distributor such as an overhead openable hopper. The pins (40) may be stationary or movable relative to the vibrating tray (22).

Abstract: The invention relates to an apparatus for the heating of roofing material. The apparatus comprising: air supply means (86); an elongated tubular combustion chamber (10) with a first end (11) and a second end and having a wall (30) surrounding a longitudinal axis (A) of said combustion chamber (10) and including an exit for hot air at said second end (12) and at least one air entrance (50) near said first end (11) for delivery of a primary air flow. A burner arrangement is disposed essentially centrally within said combustion chamber near said first end. The burner arrangement comprises means for injection of fuel (88) and means for ignition of said fuel (80). The first end (11) of the combustion chamber being essentially air-tight, and said at least one air entrance (50) being located in the wall (30) of the combustion chamber (10) near said first end (11). The air entrance (50) comprises means to produce a helical current of air around said longitudinal axis (A) of the combustion chamber (10).

Abstract: A novel intracellular signalling activity of coagulation factor VII (FVII) in cells expressing tissue factor (TF) is described. The present invention relates to use of FVIIa or another TF agonist, or FVIIai or another TF antagonist for the preparation of a medicament for modulation of FVIIa-induced activation of the MAPK signalling pathway in a patient. Moreover the present invention relates to a method of treatment, and a method of detecting the activity of compounds, in particular drug candidates, that interact with the FVIIa mediated intracellular signalling pathway.

Abstract: A cartridge having a distal end provided with a mechanical coding. The coding has the form of a circular protrusion where the circular outer diameter is dedicated a specific concentration of insulin contained in the cartridge. The distal end of the cartridge is fitted in to a circular contour in the housing. The outer diameter of the protrusion on the distal end of the cartridge is chosen as a larger diameter for a higher concentration of insulin. In this way only a cartridge containing the correct concentration or a lower concentration fits into a delivery system designed for a specific concentration of insulin.

Abstract: The invention relates to neublastin neurotrophic factor polypeptides, nucleic acids encoding neublastin polypeptides, and antibodies that bind specifically to neublastin polypeptides, as well as methods of making and methods of using the same.

Abstract: The present invention concerns an apparatus and a method for making and compressing growth medium pots, where the growth medium pots are made as a growth medium pipe, where a tubular wall is formed by the fibre-containing material, where the growth medium pipe contains slightly compressed growth medium. It is the purpose of the invention to achieved an apparatus and a method for cheap and efficient production of firmly compressed growth medium pots, where the growth medium pots are rapidly and efficiently compressed contained in the fibre-containing material.

Abstract: The present invention relates to dopamine D4 ligands having the general formula I wherein R1-R10, W, X, Y1-Y4, and n are as described herein. The compounds of the invention are potent dopamine D4 receptor ligands.

Abstract: The invention relates to a router which may be used for amplification of a bidirectional optical signal using a single optical amplifier. An advantageous embodiment of the invention comprises two 3 dB couplers which are serially connected via a delay element. According to the embodiment, the delay element comprises a difference in distance ?L between the two optical branches which connect the two 3 dB couplers.

Abstract: The present invention relates to an ion exchange chromatography process for purifying a peptide from a mixture containing the peptide and related impurities, and to an industrial method including such ion exchange chromatography process.

Abstract: A new Clematis plant with a compact growth habit, profuse, violet-blue flowers, and continuous summer flowering. The variety successfully propagates from softwood cuttings and is suitable for cultivation commercial nursery culture. This new and distinct variety has shown to be uniform and stable in the resulting generations from asexual propagation from vegetative cuttings.

Abstract: A new garden rose plant of the compact floribunda class which has abundant, red flowers and attractive foliage. This new and distinct variety has shown to be uniform and stable in the resulting generations from asexual propagation.