Abstract: The invention relates to polypeptides comprising an amino acid sequence which is an analogue of pramlintide, pharmaceutical compositions comprising these polypeptides, and these polypeptides for use as medicaments.

Abstract: A process is provided for the preparation of a highly pure albumin solution the process comprising subjecting albumin (preferably expressed and secreted by transformed yeast) to a series of chromatographic steps. Preferably, the process comprises the steps of positive mode cation exchange chromatography, positive mode anion exchange chromatography, positive mode affinity chromatography, negative mode affinity chromatography (preferably using immobilized aminophenylboronic acid), negative mode cation exchange chromatography, and negative or positive mode anion exchange chromatography. A process for reducing the level of nickel in an albumin solution is also disclosed, as is a recombinant albumin coding sequence comprising two or more in-frame translation stop codons.

Abstract: The USB device (e.g. an audio class device) comprises a USB bus interface that connects to an upstream USB port and a USB logical device that provides first USB endpoints for upstream communication on a first channel. The USB host comprises a USB host controller that connects to a downstream USB port, and a USB driver that provides second USB endpoints for downstream communication on a second channel; wherein the USB host operates concurrently with the USB device. The processor is configured to communicate data between the first channel and the second channel via the first USB endpoints and the second USB endpoints, respectively.

Abstract: A method for producing cottage cheese by using Streptococcus thermophilus bacteria.

Abstract: A headset (1) comprising an attachment device (2) for attaching the headset (1) to the head of a user and a speaker housing (3). The speaker housing 3 is connected slidable along and rotatable about a first axis (X) to the attachment device (2), such that it can be placed into a selected longitudinal and angular position within a longitudinal interval (LI) and an angular interval (AI). The longitudinal interval (LI) comprises a first zone (Z1) and a second zone (Z2), and the speaker housing (3) can rotate through a first angular interval (AI1), when in the first zone (Z1) and through a second angular interval (AI2), when in the second zone (Z2). The first angular interval (AI1) is larger than the second angular interval (AI2).

Abstract: The invention relates to methods of preparing and purifying conjugates between Granulocyte Colony Stimulating Factor and PEG moieties. The conjugates are linked via an intact glycosyl linking group that is interposed between and covalently attached to the peptide and the modifying group. The conjugates are purified using various chromatography methods.

Abstract: A method of estimating diaphragm excursion of an electrodynamic loudspeaker may be performed using audio signals. An audio output signal may be applied to a voice coil of the electrodynamic loudspeaker through an output amplifier to produce sound. A detected voice coil current and a determined voice coil voltage may be applied to a linear adaptive digital loudspeaker model that has a plurality of adaptive loudspeaker parameters. The parameter values of the adaptive loudspeaker parameters may be computed based on the linear adaptive digital loudspeaker model and applied to a non-linear state-space model of the electrodynamic loudspeaker. For the non-linear state-space model, a predetermined non-linear function may be applied to at least one of the plurality of received parameter values to compute at least one non-linearity compensated parameter value of the adaptive loudspeaker parameters, to determine an instantaneous excursion of the diaphragm.

Abstract: The invention relates to an optical detector for determining the relative wind direction (attack angle) relative to a rotating or stationary wind turbine rotor. The optical detector comprises an output part which transmits distinguishable light beams out from a rotor blade in different predetermined directions. The beams may be distinguishable by light color, by the time the individual beams are emitted and/or by different amplitude modulation frequencies or other modulations of the individual beams. By determining pulse times of scattered light from wind borne particles moving in or through the different distinguishable beams, or determining the number of pulses within a period, it is possible to determine the relative wind direction or angle of attach as the predetermined direction of a beam which has the longest pulse times or the fewest number of pulses within a given period of time.

Abstract: An assay for citrullinated fragments of SOCS-2, Alpha 1 anti tyrpsin, versican, biglycan, laminin, or other protein having a terminal antibody binding site comprising citrulline in a blood derived sample shows diagnostic relevance in relation to rheumatoid arthritis or fibrotic disease.

Abstract: The application relates to a binaural hearing assistance system comprising left and right hearing assistance devices adapted for being located at or in a left and right ear, respectively, of a user, each of the left and right hearing assistance devices comprising a) an input unit for providing one or more electric input signals based on one or more input sounds of a sound field surrounding the binaural hearing assistance system; b) a source separation unit for separating and localizing one or more sound sources Ss in said sound field relative to the input transducer unit based on said one or more electric input signals, and providing respective separated sound source signals Xs, and localization parameters LPs of said one or more sound sources (s=1, 2, . . .

Abstract: A wind turbine blade having an elongated blade body extending along a longitudinal axis and having an upper skin and a lower skin, the lower skin spaced from the upper skin in a thickness direction of the blade body, the upper skin and/or lower skin having a laminated layer, the laminated layer having an outer layer wherein the outer layer forms part of the upper and/or lower skin respectively, an inner layer spaced from the outer layer in the thickness direction; and an intermediate layer sandwiched between the outer layer and inner layer, the intermediate layer having a plurality of heat transfer paths within the intermediate layer for transferring heat.

Abstract: A heating assembly for a blade of a wind turbine generator, said heating assembly comprising: a heat reservoir positioned within a cavity of said blade, said heat reservoir in communication with a heat source; said heat reservoir including a plurality of orifices for venting hot air from said heat reservoir.

Abstract: A phase change material (PCM) pack (1) for an air conditioning system comprises phase change material sealed between a first thermally conductive layer (2) forming a first outer surface of the PCM pack and a second thermally conductive layer (2) forming a second outer surface of the PCM pack. At least the first or second outer surface of the PCM pack takes the form of a substantially planar surface having defined therein a plurality of depressions (4) deviating from the planar surface towards the interior of the PCM pack in a direction perpendicular to the planar surface. The depressions improve heat transfer between the pack and an airflow passing over the surface of the PCM pack.

Abstract: A method of fabricating a composite part comprising fibre reinforced material in a mould (10a, 10b, 10c), the method comprising the steps of: depositing fibre material on a mould surface; covering the fibre material with a vacuum film to create a mould cavity that contains the fibre material and is substantially sealed; evacuating air from the mould cavity; detecting if there is an air leak into the mould cavity with an acoustic camera unit (31) during and/or after the step of evacuating air from the mould cavity.

Abstract: The invention relates to malodor controlling bacteria and related methods and compositions for the control and prevention of malodor.

Abstract: A stable pharmaceutical formulation containing an insulin derivative can conveniently be prepared by adding glycerol, phenol, m-cresol and zinc ions to it.

Abstract: Provided are isolated polypeptides having glucoamylase activity, catalytic domains, and polynucleotides encoding the polypeptides, catalytic domains. Also provided are nucleic acid constructs, vectors and host cells comprising the polynucleotides as well as methods of producing and using the polypeptides, catalytic domains.

Abstract: A hearing aid includes: an input transducer for provision of an audio signal in response to sound; a hearing loss model for calculation of a hearing loss as a function of a signal level of the audio signal; and a probabilistic hearing loss compensator that is configured to process the audio signal into a hearing loss compensated audio signal in such a way that the hearing loss is restored to normal hearing in accordance with the hearing loss model.

Abstract: A hearing aid includes: an input transducer for generating an audio signal; a feedback suppression circuit configured for modelling a feedback path of the hearing aid; a subtractor for subtracting an output signal of the feedback suppression circuit from the audio signal to form a feedback compensated audio signal; a signal processor that is coupled to an output of the subtractor for processing the feedback compensated audio signal to perform hearing loss compensation; and a receiver that is coupled to an output of the signal processor for converting the processed feedback compensated audio signal into a sound signal; wherein the hearing aid further comprises a gain processor for performing gain adjustment of the feedback compensated audio signal based at least on an estimate of a residual feedback signal of the feedback compensated audio signal, wherein the estimate of the residual feedback signal is based at least on the audio signal.