Abstract: The present invention describes a methodology for exploiting differences in the aging rates of X- and Y-bearing spermatozoa to enable pre-selection of gender of offspring in mammals.
Type:
Application
Filed:
November 1, 2004
Publication date:
June 16, 2005
Applicant:
ABS Global,Inc.
Inventors:
Dennis Funk, Stuart Revell, Marvin Pace, Jeffery Betthauser, Marjorie Faust
Abstract: A process of parthenogenic activation of mammalian oocytes which includes increasing intercellular levels of divalent cations in the oocyte; and reducing phosphorylation of cellular proteins in the oocyte. One method of accomplishing this is by introducing Ca.sup.2+ free cation, such as ionomycin, to the oocyte and then preventing phosphorylation of the cellular proteins within the oocyte by adding a serine-threonine kinase inhibitor, such as 6-dimethylaminopurine (DMAP).
Type:
Grant
Filed:
June 6, 1995
Date of Patent:
December 1, 1998
Assignee:
ABS Global, Inc.
Inventors:
Joan L. Susko-Parrish, David L. Northey, M. Lorraine Leibfried-Rutledge, Steven L. Stice