Patents Assigned to Acelrx Pharmaceuticals, Inc.
  • Bioadhesive drug formulations for oral transmucosal delivery
    Patent number: 8252328
    Abstract: Formulations for controlled delivery of oral transmucosal medications are provided. The formulations are characterized as hydrogel-forming or eroding-types which are bioadhesive and provide for controlled and sustained release of the medication such that enhanced bioavailability and efficacy is provided.
    Type: Grant
    Filed: January 5, 2007
    Date of Patent: August 28, 2012
    Assignee: Acelrx Pharmaceuticals, Inc.
    Inventors: Stelios Tzannis, Pamela Palmer, Thomas Schreck, Larry Hamel, Andrew I. Poutiatine
  • Bioadhesive drug formulations for oral transmucosal delivery
    Patent number: 8252329
    Abstract: Bioadhesive drug formulations that adhere to an oral mucosal membrane of a subject are provided together with single dose applicators and devices for delivering the drug formulations to the oral mucosa, and methods for using the same.
    Type: Grant
    Filed: July 3, 2007
    Date of Patent: August 28, 2012
    Assignee: Acelrx Pharmaceuticals, Inc.
    Inventors: Stelios Tzannis, Larry Hamel, Pamela Palmer, Thomas Schreck, Andrew I. Poutiatine
  • Small-volume oral transmucosal dosage
    Patent number: 8231900
    Abstract: Small-volume oral transmucosal dosage forms or NanoTabs® comprising a predetermined amount of a pharmaceutically active drug are provided. Exemplary applications include use of the NanoTabs® to administer a drug for the treatment of acute, post-operative or breakthrough pain.
    Type: Grant
    Filed: October 11, 2007
    Date of Patent: July 31, 2012
    Assignee: Acelrx Pharmaceutical, Inc.
    Inventors: Pamela Palmer, Thomas Schreck, Stelios Tzannis, Larry Hamel, Andrew I. Poutiatine
  • Small volume oral transmucosal dosage forms containing sufentanil for treatment of pain
    Patent number: 8226978
    Abstract: Compositions, methods and systems for administration of small volume sufentanil-containing drug dosage forms to the oral mucosa of a subject are disclosed.
    Type: Grant
    Filed: December 28, 2007
    Date of Patent: July 24, 2012
    Assignee: AcelRx Pharmaceuticals, Inc.
    Inventors: Pamela Palmer, Thomas Schreck, Stelios Tzannis, Larry Hamel, Andrew I. Poutiatine, Charles Rampersaud, Bruce Edwards
  • Small-volume oral transmucosal dosage forms
    Patent number: 8202535
    Abstract: Small-volume oral transmucosal dosage forms or NanoTabs® comprising a predetermined amount of a pharmaceutically active drug are provided. Exemplary applications include use of the NanoTabs® to administer a drug for the treatment of acute, post-operative or breakthrough pain.
    Type: Grant
    Filed: January 5, 2007
    Date of Patent: June 19, 2012
    Assignee: Acelrx Pharmaceuticals, Inc.
    Inventors: Pamela Palmer, Thomas Schreck, Stelios Tzannis, Larry Hamel, Andrew I. Poutiatine
  • Oral Transmucosal Administration of Sufentanil
    Publication number: 20110288128
    Abstract: Compositions and methods for administration of sufentanil-containing drug formulations to the oral mucosa of a subject are disclosed.
    Type: Application
    Filed: May 21, 2010
    Publication date: November 24, 2011
    Applicant: AcelRx Pharmaceuticals, Inc.
    Inventors: Pamela Palmer, Shamim Pushpala, Evangeline Cruz, Larry Hamel, Linda Judge
  • Compositions and Methods for Mild Sedation, Anxiolysis and Analgesia in the Procedural Setting
    Publication number: 20110091544
    Abstract: Small tablets for use in procedural sedation, anxiolysis and analgesia comprising the combination sufentanil and triazolam administered via the oral transmucosal route and methods for using the same are provided.
    Type: Application
    Filed: October 16, 2009
    Publication date: April 21, 2011
    Applicant: ACELRX PHARMACEUTICALS, INC.
    Inventor: Pamela Palmer
  • Storage and Dispensing Devices for Administration of Oral Transmucosal Dosage Forms
    Publication number: 20100253476
    Abstract: Dispensing devices and systems for oral transmucosal administration of small volume drug dosage forms to the oral mucosa are provided. The dispensing device may be a single dose applicator (SDA), or an electromechanical device comprising a means for patient identification such as a wrist worn RFID tag and annular bidirectional antenna together with a lock-out feature.
    Type: Application
    Filed: March 16, 2010
    Publication date: October 7, 2010
    Applicant: ACELRX PHARMACEUTICALS, INC.
    Inventors: Andrew Poutiatine, Bruce Edwards, Charles Rampersaud
  • Small-volume oral transmucosal dosage forms
    Publication number: 20100256190
    Abstract: Small-volume oral transmucosal dosage forms or NanoTabs® comprising a predetermined amount of a pharmaceutically active drug are provided. Exemplary applications include use of the NanoTabs® to administer a drug for the treatment of acute, post-operative or breakthrough pain.
    Type: Application
    Filed: January 5, 2007
    Publication date: October 7, 2010
    Applicant: AcelRx Pharmaceuticals, Inc.
    Inventors: Pamela Palmer, Thomas Schreck, Stelios Tzannis, Larry Hamel, Andrew I. Poutiatine
  • Storage and Dispensing Devices for Administration of Oral Transmucosal Dosage Forms
    Publication number: 20100137836
    Abstract: Compositions, methods and systems for oral transmucosal administration of small volume sufentanil-containing drug dosage forms to a subject using a drug dispensing device are disclosed. The drug dispensing device may provide for administration of multiple doses, a single dose at a time or be a single dose applicator (SDA).
    Type: Application
    Filed: December 28, 2007
    Publication date: June 3, 2010
    Applicant: ACELRX PHARMACEUTICALS, INC.
    Inventors: Pamela Palmer, Andrew I. Poutiatine, Charles Rampersaud, Bruce Edwards, Edmond Chiu, Thomas Schreck, Stelios Tzannis, Larry Hamel
  • Sufentanil Solid Dosage Forms Comprising Oxygen Scavengers and Methods of Using the Same
    Publication number: 20100130551
    Abstract: Compositions and methods effective to minimize or eliminate the presence of oxidative degradation products in solid dosage forms comprising sufentanil are provided.
    Type: Application
    Filed: November 21, 2008
    Publication date: May 27, 2010
    Applicant: AcelRx Pharmaceuticals, Inc.
    Inventors: Shamim Pushpala, Lary Hamel, Stelios Tzannis, Evangeline Cruz
  • Small Volume Oral Transmucosal Dosage Forms Containing Sufentanil for Treatment of Pain
    Publication number: 20100105735
    Abstract: Compositions, methods and systems for administration of small volume sufentanil-containing drug dosage forms to the oral mucosa of a subject are disclosed.
    Type: Application
    Filed: December 28, 2007
    Publication date: April 29, 2010
    Applicant: ACELRX PHARMACEUTICALS, INC.
    Inventors: Pamela Palmer, Thomas Schreck, Stelios Tzannis, Larry Hamel, Andrew I. Poutiatine, Charles Rampersaud, Bruce Edwards
  • Small-volume oral transmucosal dosage
    Publication number: 20090131479
    Abstract: Small-volume oral transmucosal dosage forms or NanoTabs® comprising a predetermined amount of a pharmaceutically active drug are provided. Exemplary applications include use of the NanoTabs® to administer a drug for the treatment of acute, post-operative or breakthrough pain.
    Type: Application
    Filed: October 11, 2007
    Publication date: May 21, 2009
    Applicant: AcelRx Pharmaceuticals, Inc.
    Inventors: Pamela Palmer, Thomas Schreck, Stelios Tzannis, Larry Hamel, Andrew I. Poutiatine
  • COMPOSITIONS AND METHODS FOR PROCEDURAL SEDATION AND ANALGESIA USING ORAL TRANSMUCOSAL DOSAGE FORMS
    Publication number: 20090048237
    Abstract: Dosage forms for procedural sedation and analgesia comprising the combination of an opioid such as sufentanil and a benzodiazepine such as triazolam for administration via the oral transmucosal route and methods for using the same are provided.
    Type: Application
    Filed: August 7, 2008
    Publication date: February 19, 2009
    Applicant: ACELRX PHARMACEUTICALS, INC.
    Inventors: Pamela Palmer, Stelios Tzannis, Thomas Schreck
  • Small volume oral transmucosal dosage forms containing sufentanil for treatment of pain
    Publication number: 20080268023
    Abstract: Compositions, systems and methods for administration of small volume sufentanil drug dosage forms to the sublingual mucosa of a subject for treatment of pain using a device are disclosed.
    Type: Application
    Filed: November 14, 2007
    Publication date: October 30, 2008
    Applicant: AcelRx Pharmaceuticals, Inc.
    Inventors: Pamela Palmer, Thomas Schreck, Stelios Tzannis, Larry Hamel, Andrew I. Poutiatine, Charles Rampersaud, Bruce Edwards
  • Bioadhesive drug formulations for oral transmucosal delivery
    Publication number: 20080166404
    Abstract: Bioadhesive drug formulations that adhere to an oral mucosal membrane of a subject are provided together with single dose applicators and devices for delivering the drug formulations to the oral mucosa, and methods for using the same.
    Type: Application
    Filed: July 3, 2007
    Publication date: July 10, 2008
    Applicant: AcelRx Pharmaceuticals, Inc.
    Inventors: Stelios Tzannis, Larry Hamel, Pamela Palmer, Thomas Schreck, Andrew I. Poutiatine
  • Storage and dispensing devices for administration of oral transmucosal dosage forms
    Publication number: 20080164275
    Abstract: Drug storage and dispensing devices for dispensing dosage forms to the oral mucosa of a patient are disclosed. The drug storage and dispensing device is a single dose applicator or a device which includes a means to retard or prevent saliva and/or moisture ingress such that the drug dosage forms in the device remain dry prior to administration.
    Type: Application
    Filed: July 3, 2007
    Publication date: July 10, 2008
    Applicant: AcelRx Pharmaceuticals, Inc.
    Inventors: Andrew I. Poutiatine, Charles Rampersaud, Bruce Edwards, Edmond Chiu, Stelios Tzannis, Pamela Palmer, William Kolosi, Sascha Retailleau
  • Methods for administering small volume oral transmucosal dosage forms using a dispensing device
    Publication number: 20080147044
    Abstract: Systems and methods for administration of small volume sufentanil drug dosage forms to the sublingual mucosa of a subject using a device are disclosed. The dispensing device includes a lock-out feature and a means to retard or prevent saliva and/or moisture ingress such that the drug dosage forms in the device remain dry prior to administration.
    Type: Application
    Filed: October 30, 2007
    Publication date: June 19, 2008
    Applicant: AcelRx Pharmaceuticals, Inc.
    Inventors: Pamela Palmer, Andrew I. Poutiatine, Charles Rampersaud, Bruce Edwards, Edmond Chiu, Thomas Schreck, Stelios Tzannis, Larry Hamel
  • Bioadhesive drug formulations for oral transmucosal delivery
    Publication number: 20070207207
    Abstract: Formulations for controlled delivery of oral transmucosal medications are provided. The formulations are characterized as hydrogel-forming or eroding-types which are bioadhesive and provide for controlled and sustained release of the medication such that enhanced bioavailability and efficacy is provided.
    Type: Application
    Filed: January 5, 2007
    Publication date: September 6, 2007
    Applicant: AcelRx Pharmaceuticals, Inc.
    Inventors: Stelios Tzannis, Pamela Palmer, Thomas Schreck, Larry Hamel, Andrew Poutiatine