Abstract: In one embodiment, there is disclosed a lead locking mechanism for use in a header component of an implantable pulse generator. In certain embodiments, the lead locking mechanism comprises a first locking member positioned to engage a surface of at least two leads; a second locking member positioned to also engage a surface of at least two leads, and a coupling member coupling the first locking member to the second locking member.

Abstract: An LED light bar comprises a housing, a circuit board with a plurality of separated portions located on the housing, a plurality of LED package devices disposed on the circuit board and electrically connecting to the circuit board, and a plurality of power dispensers respectively electrically connecting to the separated portions of the circuit board. The plurality of LED package devices is divided into a plurality of groups respectively on the plurality of separated portions of the circuit board, wherein the plurality of LED package devices of each of the groups forms a closed loop. Each separated portion of the circuit board includes a metal layer on the housing, an insulating layer on the metal layer and a circuit layer on the insulating layer. Each group of the LED package devices is on a corresponding circuit layer.

Abstract: The present invention discloses the pH-sensitive nanoparticles composed of pH-sensitive polymer, hydrophobic material, internal stabilizer, external stabilizer content and insulin drug. The present invention also includes a method for preparation of pH-sensitive nanoparticles, in particular, a multiple emulsions solvent evaporation method. The pH-sensitive nanoparticles of the present invention show good pH-sensitive property with 100-300 nanometer particle size. Significant decrease in blood glucose level is observed in streptozotocin (STZ)-induced diabetic rats and the bioavailability of insulin is more than 10% after oral administration of the insulin-loaded pH-sensitive nanoparticles.

Abstract: An angioplasty assembly having a guidewire device for use in peripheral vascular and coronary angioplasty applications. The guidewire invention has one or more angioplasty devices mounted directly on the distal tip of the guidewire. In one embodiment the angioplasty device includes an angioplasty balloon. In another embodiment, the device includes a stent balloon with expandable stent, or a self-expanding stent, or combinations of these. Preferably, the guidewire is housed within a hypotube. Optionally, the hypotube may house a retractable piercing element with a distal loop 3 suitable for piercing a vessel wall. The guidewire allows an angioplasty procedure to be completed using a single device.

Abstract: Disclosed is a hybrid porous carbon fiber and a method for fabrication thereof. Such fabricated porous carbon fibers contain a great amount of mesopores as a porous structure readily penetrable by electrolyte. Accordingly, the hybrid porous carbon fibers of the present disclosure are suitable for manufacturing electrodes with high electric capacity.

Abstract: A light emitting diode (LED) comprises a substrate, an epitaxial layer and an aluminum nitride (AlN) layer sequentially disposed on the substrate. The AlN layer comprises a plurality of stacks separated from each other, wherein the epitaxial layer entirely covers the plurality of stacks of the AlN layer. The AlN layer with a plurality of stacks reflects upwardly light generated by the epitaxial layer and downwardly toward the substrate to an outside of LED through a top plan of the LED. A method for forming the LED is also disclosed.

Abstract: The invention relates to an enteric-coated capsule containing cationic nanoparticles for oral insulin delivery, in particular to a type of cationic nanoparticle including a polycationic and mucoadhesive polymer and a biodegradable polymer, wherein each of the nanoparticles has positive surface charge and enhanced permeability for paracellular insulin delivery; the enteric-coated capsule further includes a pH-sensitive polymer as the coating. The enteric-coated capsule containing cationic nanoparticles, when being orally administered to a subject, are configured to prevent the acidic degradation of the active substance such as insulin before being released from said cationic nanoparticles to a specific absorption site along the gastrointestinal tract.

Abstract: Provided herein are a circuit and method for dynamically controlling operational amplifier (op-amp) offset for photodetector applications using a variable trimming circuit coupled to a test node and an op-amp.

Abstract: A manufacturing method for an LED with roughened lateral surfaces comprises following steps: providing an LED wafer with an electrically conductive layer disposed thereon; providing a photoresist layer on the electrically conductive layer; roughening a lateral surface of the electrically conductive layer by wet etching; forming a depression in the LED wafer by dry etching and roughening a sidewall of the LED wafer defining the depression; and disposing two pads respectively in the depression and the conducting layer. The disclosure also provides an LED with roughened lateral surfaces. A roughness of the roughened lateral surfaces is measurable in micrometers.

Abstract: This invention related to a cationically and hydrophilically modified polygalactomannan having repeating units with an average D-mannosyl to D-galactosyl residue ratio of at least 5 to 1 and to compositions containing the same. A portion of the hydrogen atoms of hydroxyl groups situated on the mannosyl and galactosyl residues of the galactomannan are replaced with a hydrophilic and a cationic substituent.

Abstract: A chuck assembly has a wafer chuck attached to a shaft that has a passage defined therewithin. The chuck assembly also has a seal module that has a rotatable assembly and a fixed assembly. The rotatable assembly is disposed around and anchored to the shaft and has a spacer, a rotatable collar, a rotatable diaphragm, and a rotatable seal ring connected to the rotatable collar through the diaphragm with a leak-tight seal. The fixed assembly is disposed around the spacer and has a fixed collar and a fixed seal ring that is sealed to the fixed collar with a leak-tight seal. The fixed collar has a passage defined therewithin that has an opening that connects through the spacer to the passage defined within the shaft. The chuck assembly further includes a housing, to which the fixed assembly is fastened, that may be affixed to a base.

Abstract: Stent designs for use in vessels, such as the carotid and coronary arteries, are disclosed. The stents consist of a plurality of radially expandable cylindrical elements generally aligned on a common longitudinal stent axis and interconnected by one or more interconnecting members placed so that the stent is flexible in a longitudinal direction. The cylindrical elements form a generally serpentine wave pattern transverse to the longitudinal axis between alternating valley portions and peak portions. The interconnecting members are attached to the double-curved portions to connect a cylindrical element to an adjacent cylindrical element and interconnecting members are attached to the inverted double-curved portions to connect the cylindrical element to the other adjacent cylindrical element. The stent designs include both a six crown and an eight crown stent which exhibit flexibility and sufficient radial strength to support the vessel.

Abstract: Antimony, germanium and tellurium precursors useful for CVD/ALD of corresponding metal-containing thin films are described, along with compositions including such precursors, methods of making such precursors, and films and microelectronic device products manufactured using such precursors, as well as corresponding manufacturing methods. The precursors of the invention are useful for forming germanium-antimony-tellurium (GST) films and microelectronic device products, such as phase change memory devices, including such films.

Abstract: A composition that may be used to retain moisture within fresh concrete as it cures to optimize the curing of the concrete may include one or more hardening and densifying agents and one or more temporary moisture sealing agents. Additionally such a composition may include a siliconate. The hardening and densifying agent of such a composition may penetrate the surface of fresh concrete to react with free lime, providing the fresh concrete with a strong surface. The temporary moisture sealing agent may form a moisture barrier on the surface of the fresh concrete to prevent moisture from escaping from the fresh concrete before the fresh concrete has sufficiently cured. The temporary moisture sealing agent may degrade within a matter of days, facilitating its removal from the surface of the concrete once the concrete has cured and enabling further treatment of the surface without undue delay.

Abstract: An LED package includes a substrate, an LED chip arranged on the substrate, and a light transmission layer arranged on a light output path of the LED chip. The substrate includes a first electrode and a second electrode separated and electrically insulated from the first electrode. The LED chip is electrically connected to the first electrode and the second electrode of the substrate. The light transmission layer comprises two parallel transparent plates and a fluorescent layer sandwiched between the two transparent plates. The LED package further includes a transparent encapsulation layer sealing the LED chip therein, and in one embodiment, the light transmission layer is located on the encapsulation layer and in another embodiment, the encapsulation layer also seals the light transmission layer therein. A method for manufacturing the LED package is also provided.

Abstract: To provide a sulfur-system positive electrode for lithium-ion battery, sulfur-system positive electrode which is good in the cyclability and the other characteristics, and a lithium-ion secondary battery including that positive electrode. In a positive electrode for lithium-ion secondary battery, the positive electrode having: a current collector; and an electrode layer that is formed on a surface of the current collector, and which includes a binder resin, an active material and a conductive additive, the positive electrode is characterized in that: the active material includes a sulfur-modified polyacrylonitrile that is produced by heating a raw-material powder including a sulfur powder and a polyacrylonitrile powder in an enclosed nonoxidizing atmosphere; and the binder resin includes a polyimide resin and/or a polyamide-imide resin.

Abstract: An electronic circuit includes a differential input section, a current mirror section, an operational amplifier, an inverter, and a compensation voltage generator. The differential input section and the current mirror section are coupled together, forming a first common drain node and a second common drain node. The current mirror section has two p-type transistors coupled together at a common gate node. The operational amplifier has a positive input coupled to the first common drain node, a negative input coupled to the compensation voltage generator, and an output coupled to the common gate node. The inverter has an input node coupled to the second common drain node. The compensation voltage generator provides a compensation voltage to replicate a switching threshold voltage of the inverter.

Abstract: A freewheeling MOSFET is connected in parallel with the inductor in a switched DC/DC converter. When the freewheeling MOSFET is turned on during the switching operation of the converter, while the low-side and energy transfer MOSFETs are turned off, the inductor current circulates or “freewheels” through the freewheeling MOSFET. The frequency of the converter is thereby made independent of the lengths of the magnetizing and energy transfer stages, allowing far greater flexibility in operating and converter and overcoming numerous problems associated with conventional DC/DC converters. In one embodiment the freewheeling MOSFET is an N-channel MOSFET with its body connected to circuit ground and not shorted to either its source or its drain.

Abstract: The present invention provides metal-porphyrin carbon nanostructures, which have excellent oxygen reduction performance and are useful as materials for fuel cell electrodes.

Abstract: In some embodiments, a paddle lead is implanted within a patient such that the electrodes are positioned within the cervical or thoracic spinal levels. An electrode combination on a first row of electrodes can be determined that is effective for a first pain location with minimal effects on other regions of the body. The first pain location can be addressed by stimulating a first dorsal column fiber due to the relatively fine electrical field resolution achievable by the multiple columns. Then, another electrode combination on a second row of electrodes can be determined for a second pain location with minimal effects on other regions. The second pain location could be addressed by stimulating a second dorsal column fiber. After the determination of the appropriate electrodes for stimulation, the patient's IPG can be programmed to deliver pulses using the first and second rows according to the determined electrode combinations.