Abstract: The present invention relates to methods of detecting analytes in a molecular array. More specifically, the invention relates to compositions and methods of illuminating or irradiating analytes bound to a feature on an array.
Abstract: A mass spectrometry system comprises a panel movable between an open and closed position relative to a housing. At least part of ion-optics is mounted to the panel. The housing surrounds ion-optics and a partition forms a gas barrier separating vacuum-chambers within the housing when the panel is in the closed position. The gas barrier formed by the partition is broken when the panel moves to the open position.
Type:
Application
Filed:
February 3, 2009
Publication date:
May 28, 2009
Applicant:
AGILENT TECHNOLOGIES, INC.
Inventors:
Douglas J. King, Thomas Patrick Doherty, Jeffrey Thomas Kernan
Abstract: A method of testing multiple fluid samples with multiple biopolymer arrays. A cover is assembled to a contiguous substrate carrying on a first side, multiple arrays each with multiple regions of biopolymers linked to the substrate, such that the cover and the substrate together form a plurality of chambers each containing a biopolymer array and each being accessible through its own port. Multiple fluid samples are introduced into respective chambers through a port of each such that the fluid samples contact respective arrays. A binding pattern of the arrays is observed. An apparatus and kit useful in such methods, are also provided.
Type:
Grant
Filed:
May 23, 2005
Date of Patent:
May 26, 2009
Assignee:
Agilent Technologies, Inc.
Inventors:
SueAnn C. Dahm, Arthur Schleifer, Carol T. Schembri, Douglas A. Amorese
Abstract: When first and second measuring equipment connected to switches are switched to measure multiple types of electronic characteristics of a device under test which is a semiconductor device, the device under test is disconnected from the second measuring equipment and is connected to the first measuring equipment. Thereafter, the first measuring equipment applies a voltage to the device under test via the switches so that the voltage of the first measuring equipment matches the output voltage of the second measuring equipment. The device under test is then disconnected from the first measuring equipment and is connected to the second measuring equipment for measurement.
Abstract: A process for producing a chromatographic stationary phase for use in reversed-phase chromatography. Chromatographic stationary phases prepared according to the methods of the current invention and liquid chromatography columns, which include the stationary phases, are also provided.
Abstract: An apparatus for collecting lubricant, such as from a vacuum pump, is disclosed. In certain embodiments the apparatus includes a cabinet for retaining a vacuum pump and a variable depth basin beneath the cabinet for collecting lubricant from a vacuum pump. In specific implementations the variable depth basin is deepest proximate the front of the cabinet.
Type:
Grant
Filed:
January 28, 2005
Date of Patent:
May 19, 2009
Assignee:
Agilent Technologies, Inc.
Inventors:
Robert Dallas Ricker, Viet X. Nguyen, Bernard John Permar, Jerome M. Szczepaniak, Lindy T. Miller, Eric Alan Schneider, Bill Van Ocker
Abstract: Methods and devices for producing a nucleic acid arrays using in situ nucleic acid array synthesis protocols are provided. A feature of certain embodiments of the invention is that control probes are produced in collections of features, e.g., columns, of the arrays that have been selected according to a particular efficient control probe feature/column selection protocol. A feature of certain other embodiments of the invention is that an “all-bases-all-layers” probe set is produced in at least one of column of the arrays. Also provided are devices configured for use in the subject methods, as well as arrays produced using the subject methods and devices as well as methods for using such arrays.
Type:
Grant
Filed:
April 2, 2003
Date of Patent:
May 19, 2009
Assignee:
Agilent Technologies, Inc.
Inventors:
Theodore R. Sana, Eric M. Leproust, Michel G. M. Perbost, Paul K. Wolber
Abstract: Methods, devices and systems for synchronizing the execution of tests between or among multi-sided test components in a wireless environment are described. Multiple flows are initiated substantially simultaneously. Execution is then paused in at least one of the flows. The paused flow sends a request for permission to resume execution to a sync servlet. The sync servlet does not respond affirmatively to the request until an appropriate synchronization signal is received from an unpaused flow, and then only after a desired test component in the unpaused flow has been executed. The paused flow is resumed upon receiving the appropriate synchronization signal from the sync servlet.
Type:
Grant
Filed:
August 3, 2005
Date of Patent:
May 19, 2009
Assignee:
Agilent Technologies, Inc.
Inventors:
David E Bingham, Carolyn Darbie, Stephen Craig Booth
Abstract: Methods for producing ligand substrates and arrays, e.g., peptide and nucleic acid arrays, as well as the arrays produced thereby, methods for use of the arrays and kits that include the same are provided. In the subject methods, a substrate having a surface displaying photocleavable functional groups that produce surface bound photocleavage produced functional groups upon irradiation is first provided, where the photocleavable groups are then cleaved to produce a surface that displays desired functional groups. The resultant substrates, optionally after an additional functionalization step, are then contacted with ligands or monomeric precursors thereof, e.g., via deposition of each different ligand onto a different region of the surface, resulting in covalent attachment of the contacted ligands to the surface.
Abstract: A mass spectrometer sample input interface comprises a desolvation apparatus defining a desolvation pathway along which a desolvation gas flows, in a direction from upstream to downstream, the desolvation pathway having a desolvation pathway portion; and an ion pathway apparatus for defining an ion pathway for analyte solution droplets to follow, the ion pathway leading into the mass spectrometer, the ion pathway including an ion pathway portion that follows the desolvation pathway portion.
Abstract: A coupler assembly has first and second conductors with first and second dielectric supports extending along a coupling section and supporting the first and second conductors at a support section.
Type:
Grant
Filed:
November 16, 2005
Date of Patent:
May 19, 2009
Assignee:
Agilent Technologies, Inc.
Inventors:
Hassan Tanbakuchi, Michael B. Whitener, Matthew R. Richter, Glenn S. Takahashi
Abstract: In one embodiment, test execution times are determined for a plurality of tests that are to be executed for a single unit under test (UUT). Test dependencies are also determined for the tests, as are the instruments needed to execute the tests. Then, in response to the test execution times, the test dependencies, and the instruments needed to execute the plurality of tests, a plurality of different and synchronized test execution orders for the plurality of tests are developed. Each of the test execution orders specifies a sequence of tests that is to be executed for one of a plurality of UUTs that are to be tested in parallel; and, typically, the plurality of different test execution orders will be constrained to develop different test execution orders that optimize a total time to test the plurality of UUTs, a usage cost of instruments used to test the plurality of UUTs, or both. Other embodiments are also disclosed.
Type:
Grant
Filed:
May 26, 2006
Date of Patent:
May 19, 2009
Assignee:
Agilent Technologies, Inc.
Inventors:
Thomas R. Fay, William H. Wubbena, Carl E. Benvenga
Abstract: A multiport concentrator concentrates network data from different links in a network and carried on a plurality of lower speed lines into a stream of data carried on a higher speed line. A measurement system determines network statistics from the stream of data carried by the higher speed line.
Abstract: A coefficient indicating the relationship between a measurement voltage of voltage measuring unit and a voltage drop in a drain bias voltage due to drain current is determined based on at least an S parameter of a measuring system and an input impedance of the measuring unit. A voltage drop at the drain is determined from the coefficient. Based on the determined voltage drop, a drain bias voltage actually applied to the drain of an FET is determined. Also, a coefficient for converting the measurement voltage of the measuring unit into a drain current is determined based on at least an S parameter of a measuring system and the input impedance of the voltage measuring unit and an electrical length of the measuring system if necessary. Based on the determined coefficient, a drain current actually flowing in the FET is determined.
Abstract: A method for eliminating the systematic measurement errors from a measurement system, for example a vector network analyzer, such that an accurate representation of the behavior of a nonlinear device can be measured or characterized. The cross-frequency phase and absolute amplitude of the measured voltage waves applied to and emanating from the nonlinear device are measured and error corrected. These waves may be used for nonlinear device characterization or modeling.
Abstract: A method, apparatus for executing the method, and computer program products for use in such an apparatus. The method includes scanning an interrogating light across multiple sites on an array package including an addressable array of multiple features of different moieties, which scanned sites include multiple array features. Signals from respective scanned sites emitted in response to the interrogating light are detected. The interrogating light power is altered for a first site on the array package during the array scan, based on location of the first site or on a determination that the emitted signal from the first site will be outside a predetermined value absent the altering (which allows for protecting a detector against expected overly bright sites), or is altered during the array scan based on the detected interrogating light power (which allows for compensating for light source drift during an array scan).
Type:
Grant
Filed:
December 21, 2001
Date of Patent:
May 12, 2009
Assignee:
Agilent Technologies, Inc.
Inventors:
Andreas N. Dorsel, Kyle J. Schleifer, Elecia C. White, Charles S. Ladd, Debra A. Sillman
Abstract: An cabinet for retaining a vacuum pump. The cabinet includes, in certain embodiments, removable access panels that allow access to the interior of the cabinet and to a vacuum pump placed within the cabinet. In certain embodiments the cabinet includes a top surface and at least one side surface. Portions of these top and side surfaces are removable from the cabinet to allow access to a vacuum pump that can be placed within the cabinet.
Type:
Grant
Filed:
January 28, 2005
Date of Patent:
May 12, 2009
Assignee:
Agilent Technologies, Inc.
Inventors:
Robert Dallas Ricker, Viet X. Nguyen, Bernard John Permar, Jerome M. Szczepaniak, Lindy T. Miller, Eric A. Schneider, Bill Van Ocker
Abstract: In accordance with the invention, resonant quantum tunneling microscopy allows surface imaging while allowing characterization of physical properties associated with the surface.
Abstract: Embodiments of a reduced noise reduction system (“RNFDS”) include a frequency divider and a resampler in signal communication with the frequency divider. The frequency divider receives an input signal and, in response, produces a divided signal. The input signal has a first frequency and the divided signal has a second frequency, different from the first frequency. The resampler receives the input signal and the divided signal, and resamples the divided signal using the input signal as a sampling clock signal to produce a resampled output signal. The frequency divider imposes edge jitter on the divided signal. Resampling the divided signal produces the resampled output signal with an edge jitter comparable with that of the input signal.
Abstract: The system and method of the present invention combine multiple tests (15) into a batch and submit the batch for processing to exercise electronic circuits, for example, a managed network (25) such as a wireless network. The system and method insure that tests (15) are timely run by utilization of a batch submit trigger (42). When a test (15) has completed, the system and method return the results (11) of that particular test (15) to the user, regardless of whether or not the rest of the tests (15) in the batch have completed execution.