Patents Assigned to Ajinomoto Co., Inc.
  • Publication number: 20240270899
    Abstract: Polyester resins containing a structural unit represented by the following general formula (1), and has an aromatic oxycarbonyl group at its terminal: (in the formula, XCs each independently represent a divalent organic group containing at least one aromatic ring, XDs each independently represent a divalent organic group, m is an average value of the number of repetitions, and is a number satisfying 0<m?10, and * indicates a bond), afford a cured product exhibiting excellent dielectric properties and also favorable mechanical properties in combination with a cross-linkable resin.
    Type: Application
    Filed: March 28, 2024
    Publication date: August 15, 2024
    Applicant: Ajinomoto Co., Inc.
    Inventors: Ichiro OGURA, Naoya SATO
  • Patent number: 12054703
    Abstract: An agricultural or horticultural composition is provided. A composition containing a culture broth of a Bacillus bacterium having prephenate dehydratase (PD) resistant to feedback inhibition by phenylalanine.
    Type: Grant
    Filed: September 29, 2020
    Date of Patent: August 6, 2024
    Assignee: AJINOMOTO CO., INC.
    Inventors: Yuta Nagasaka, Daisuke Kitazawa, Kenichi Kaida, Atsushi Hayakawa, Daisuke Igarashi, Natalia Sergeevna Eremina, Natalia Viktorovna Stoynova, Kseniia Viktorovna Emelina
  • Patent number: 12053008
    Abstract: A method of making a microwavable frozen dumpling, whereby a raw dumpling containing a dough and one or more filling ingredients is boiled to form a boiled dumpling, and the boiled dumpling is frozen to form the microwavable frozen dumpling. The dough of the microwavable frozen dumpling includes a rice flour, an oil, and a modified cellulose polymer, and has a moisture content of at least 52.0 wt. %. A method of preparing a cooked dumpling is also provided, whereby the microwavable frozen dumpling is heated in a microwave oven without covering the microwavable frozen dumpling.
    Type: Grant
    Filed: November 12, 2021
    Date of Patent: August 6, 2024
    Assignee: AJINOMOTO CO., INC.
    Inventor: Allison Dobrich
  • Publication number: 20240251833
    Abstract: Provided is a technology for improving the flavor of food. The flavor of food is improved by adding the following ingredient (A): (A) a cell wall-containing fraction of a gram-positive bacterium.
    Type: Application
    Filed: February 2, 2024
    Publication date: August 1, 2024
    Applicant: AJINOMOTO CO., INC.
    Inventors: Miku TOYAZAKI, Moe HIRATANI, Kazuyuki HAYASHI, Masashi SUZUKI, Daiki YAHAGI, Riku USAMI, Motonaka KURODA, Masaki MIZUNO, Toshihito SEKI, Yoshinori TAJIMA
  • Publication number: 20240254328
    Abstract: Resin compositions including (A) a compound containing a radical polymerizable group having a carbodiimide structure, and at least any one of (B) a compound containing a radical polymerizable group not having a carbodiimide structure and (C) a thermosetting resin can afford a cured product having excellent mechanical strength and plating adhesion property.
    Type: Application
    Filed: February 21, 2024
    Publication date: August 1, 2024
    Applicant: Ajinomoto Co., Inc.
    Inventors: Shohei FUJISHIMA, Shu IKEHIRA
  • Publication number: 20240240167
    Abstract: Described herein is an enzyme useful for producing a target peptide, capable of producing the target peptide without requiring ATP. More specifically, provided herein is a modified enzyme includes an amino acid sequence such as a modified amino acid sequence including a mutation of one or more of the following amino acid residues: E81, I127, I136, T139, F140, G142, W143, I147, I181, I201, Q219, T229, M244, A249, P255, E256, I260, S293, N294, Y295, and I299 in an amino acid sequence of SEQ ID NO: 1, and having the following property (a) or (b) enhanced relative to an enzyme of the amino acid sequence of SEQ ID NO: 1: (a) imidazole dipeptide production activity; or (b) thermal stability.
    Type: Application
    Filed: March 27, 2024
    Publication date: July 18, 2024
    Applicant: AJINOMOTO CO., INC.
    Inventors: Mizuki Tamori, Uno Tagami, Hiroyuki Nozaki
  • Publication number: 20240237674
    Abstract: A plant protein-containing food may be prepared by the addition of a high molecular rapeseed protein and transglutaminase to a plant protein-containing composition.
    Type: Application
    Filed: March 29, 2024
    Publication date: July 18, 2024
    Applicant: AJINOMOTO CO. , INC.
    Inventors: Daisuke KITAZAWA, Rie OGURA, Koudai USUGI
  • Publication number: 20240225053
    Abstract: The present invention provides a sporulation inhibitor of Clostridium perfringens containing at least one inorganic compound at a concentration that allows Clostridium perfringens to settle in vivo, wherein the inorganic compound is at least one salt selected from the group consisting of K, Na, Mg, Ca, and Fe, and the inorganic compound is coated with a protective layer containing hydrogenated vegetable oil.
    Type: Application
    Filed: December 21, 2023
    Publication date: July 11, 2024
    Applicant: AJINOMOTO CO., INC.
    Inventors: Akinori UEHARA, Yasuteru SAKAMOTO
  • Publication number: 20240219394
    Abstract: A method for measuring a response of an olfactory receptor to a substance is provided. The test substance and the olfactory receptor are contacted under such a condition that response of adenosine receptor to the test substance is reduced, and response of the olfactory receptor to the test substance is measured.
    Type: Application
    Filed: February 5, 2024
    Publication date: July 4, 2024
    Applicant: AJINOMOTO CO., INC.
    Inventors: Chiori IJICHI, Yusuke IHARA, Yasuko SOMEKAWA, Yayoi KAWATO, Sachise KARAKAWA
  • Publication number: 20240218015
    Abstract: A method for producing an intermediate antibody regioselectively modified, which comprises: (1) mixing a solution comprising an antibody material and a solution comprising a reagent for regioselectively modifying an antibody in a micromixer to form a mixture comprising the antibody material and the reagent, wherein the reagent comprises a compound comprising an affinity substance to an antibody and a reactive group to an antibody; and (2) passing the mixture through a reaction channel to allow the antibody material and the reagent to react in the reaction channel to form a solution comprising an intermediate antibody regioselectively modified, wherein the processes (1) and (2) are continuously performed in a flow microreactor, is capable of rapidly producing a desired antibody derivative regioselectively having a functional substance or functional substances.
    Type: Application
    Filed: March 7, 2024
    Publication date: July 4, 2024
    Applicant: Ajinomoto Co., Inc.
    Inventors: Yutaka MATSUDA, Yuichi NAKAHARA, Kei YAMADA, Keisuke KATO, Yuta ENDO, Brian Alan MENDELSOHN
  • Patent number: 12024549
    Abstract: The present invention provides a technique enabling modification of a soluble protein and in particular regioselective modification of a soluble protein. More specifically, the present invention provides a compound having an affinity substance to a soluble protein, a cleavable portion, and a reactive group represented by the following Formula (I): A-L-B-R??(I) wherein A is an affinity substance to a soluble protein; L is a cleavable linker which is a divalent group comprising a cleavable portion; B is (a) a divalent group comprising a bioorthogonal functional group or (b) a divalent group comprising no bioorthogonal functional group; and R is a reactive group to the soluble protein; or a salt thereof.
    Type: Grant
    Filed: October 25, 2019
    Date of Patent: July 2, 2024
    Assignee: Ajinomoto Co., Inc.
    Inventors: Kei Yamada, Yutaka Matsuda, Tomohiro Fujii, Natsuki Shikida, Reiko Yuji, Kazutaka Shimbo, Yuji Ito
  • Publication number: 20240209409
    Abstract: A method for secretory production of a protein containing a noncanonical amino acid is provided. Secretory production of a noncanonical amino acid-containing protein is carried out by culturing a coryneform bacterium having a genetic construct for secretory expression of a protein containing a noncanonical amino acid, which is modified to express an orthogonal pair of tRNA corresponding to the noncanonical amino acid and aminoacyl tRNA synthetase.
    Type: Application
    Filed: January 2, 2024
    Publication date: June 27, 2024
    Applicant: AJINOMOTO CO., INC.
    Inventors: Kenichi Haruna, Haruna Sato, Yoshihiko Matsuda, Kenichiro Ito
  • Publication number: 20240206490
    Abstract: Cheese analogues with improved meltability and/or extensibility when heated, may be obtained by causing a protease to act on a mixture containing fat and/or oil, starch, and protein.
    Type: Application
    Filed: March 6, 2024
    Publication date: June 27, 2024
    Applicant: AJINOMOTO CO., INC.
    Inventors: Yuko FUJIMURA, Koudai USUGI, Daisuke KITAZAWA
  • Patent number: 12014854
    Abstract: Magnetic pastes which include a magnetic powder (A) and a binder resin (B), in which, in the particle diameter distribution of the component (A), the 10% particle diameter (D10) is 0.2 ?m or larger and 2.0 ?m or smaller, the 50% particle diameter (D50) is 2.0 ?m or larger and 4.3 ?m or smaller, and the 90% particle diameter (D90) is 4.3 ?m or larger and 8.5 ?m or smaller, suppress the magnetic powder from being unevenly distributed, and are useful for forming inductor elements and circuit boards.
    Type: Grant
    Filed: April 7, 2021
    Date of Patent: June 18, 2024
    Assignee: Ajinomoto Co., Inc.
    Inventors: Ichiro Oura, Tatsuya Homma, Masanori Yoda, Takayuki Tanaka
  • Publication number: 20240182862
    Abstract: A medicament for the prophylaxis or treatment of inflammatory diseases or fibrous diseases, may be produced by inducing mesenchymal stem cells by culturing neural crest cells in a medium composition for inducing mesenchymal stem cells from neural crest cells, comprising a basal medium and corticosteroid, the composition having a converted concentration of the corticosteroid in the medium composition of not less than 1.25 ?M.
    Type: Application
    Filed: December 8, 2023
    Publication date: June 6, 2024
    Applicant: AJINOMOTO CO., INC.
    Inventors: Kazuma TAKAHASHI, Shizuka BABA, Atsushi KONISHI
  • Patent number: 11999983
    Abstract: The present invention provides a method for producing a basic L-amino acid, for example, L-ornithine L-citrulline, L-arginine, L-histidine, and L-lysine by fermentation using a bacterium belonging to the family Enterobacteriaceae which has been modified to overexpress a gene encoding a protein having L-methionine/branched chain amino acid exporter activity.
    Type: Grant
    Filed: June 22, 2021
    Date of Patent: June 4, 2024
    Assignee: AJINOMOTO CO., INC.
    Inventors: Mikhail Kharisovich Ziyatdinov, Yulia Georgievna Rostova, Olga Nikolaevna Igonina, Andrei Viacheslavovich Kniazev
  • Publication number: 20240165260
    Abstract: A conjugate of an antibody and a functional substance or a salt thereof, which comprises a structural unit represented by the following formula (I): wherein Ig represents an immunoglobulin unit comprising two heavy chains and two light chains, and regioselectively forms an amide bond with a carbonyl group adjacent to Ig via an amino group in side chains of lysine residues in the two heavy chains, L1 and L2 each represent a divalent group, R1 represents a monovalent group optionally comprising a hydrophilic group, X represents a predetermined divalent group, D represents a functional substance, RA represents a side chain of a valine residue, RB represents a side chain of a citrulline residue or an alanine residue, n is 0 or 1, and an average ratio r of the amide bonds per two heavy chains is 1.5 to 2.
    Type: Application
    Filed: November 29, 2023
    Publication date: May 23, 2024
    Applicant: Ajinomoto Co., Inc.
    Inventors: Yutaka MATSUDA, Tomohiro FUJII, Ryusuke HIRAMA, Thomas MARKOTAN, Allan PRIOR, Christopher WONG, Konstantinos PLAKAS, Tomohiro WATANABE
  • Publication number: 20240130403
    Abstract: The present invention provides a sporulation inhibitor of Clostridium perfringens containing at least one inorganic compound at a concentration that allows Clostridium perfringens to settle in vivo, wherein the inorganic compound is at least one salt selected from the group consisting of K, Na, Mg, Ca, and Fe, and the inorganic compound is coated with a protective layer containing hydrogenated vegetable oil.
    Type: Application
    Filed: December 21, 2023
    Publication date: April 25, 2024
    Applicant: AJINOMOTO CO., INC.
    Inventors: Akinori UEHARA, Yasuteru SAKAMOTO
  • Patent number: 11965198
    Abstract: The present invention provides a method for producing a target substance, the biosynthetic pathway of which is ATP-dependent, for example, amino acids, nucleosides, nucleotides, isoprenoids, and peptides, by fermentation of a bacterium which has been modified to overexpress a gene encoding a protein having H+-translocating membrane-bound pyrophosphatase activity, for example, the hppA gene native to R. rubrum or a variant thereof.
    Type: Grant
    Filed: April 2, 2021
    Date of Patent: April 23, 2024
    Assignee: AJINOMOTO CO., INC.
    Inventors: Ekaterina Andrianova, Maria Kharchenko, Natalia Zakataeva, Elvira Voroshilova, Aleksander Krylov, Evgeniya Malykh, Sergei Mashko, Natalia Stoynova, Mikhail Baboshin, Lyubov Golubeva, Ekaterina Kovaleva, Mikhail Shupletsov
  • Publication number: 20240122841
    Abstract: Compositions for cosmetics, containing (A) at least one polyaspartic acid or a salt thereof, (B) zinc pyrrolidonecarboxylate, and (C) at least one aliphatic hydroxycarboxylic acid having 1 to 10 carbon atoms or a salt thereof are useful as premixed compositions used for blending polyaspartic acid or a salt thereof and zinc pyrrolidonecarboxylate stably and conveniently in cosmetic compositions.
    Type: Application
    Filed: December 22, 2023
    Publication date: April 18, 2024
    Applicant: AJINOMOTO CO., INC.
    Inventor: Eriko YAMAGUCHI