Patents Assigned to Ajou University Industry-Academic Cooperation Foundation
  • Patent number: 11554151
    Abstract: A pharmaceutical composition, dietary supplement, or food containing a Perilla frutescens fermented extract is disclosed. The composition is useful for prevention or treatment of a sleep disorder. A composition or a fiber or fragrance composition containing a Perilla frutescens fermented extract is also disclosed. A method for treating sleep disorder employing the pharmaceutical composition, dietary supplement, food, or the fiber or fragrance composition is disclosed.
    Type: Grant
    Filed: November 23, 2018
    Date of Patent: January 17, 2023
    Assignee: AJOU UNIVERSITY INDUSTRY-ACADEMIC COOPERATION FOUNDATION
    Inventors: Yi Sook Jung, Tae Ho Kim
  • Publication number: 20230000861
    Abstract: A small molecule TNF-? inhibitor is disclosed. The compound has an activity of inhibiting the formation of a TNF-? homotrimer by specifically binding to the binding cavity of a TNF-? homodimer. A composition containing the compound as well as uses of the compound and the composition in preventing or treating autoimmune diseases and/or inflammatory diseases are disclosed. Extracellular inactivation of TNF-? through protein-protein interface destruction is the most innovative and effective method for alleviating chronic systemic inflammatory states, and TIM series compounds, which have better efficacy and lower toxicity than those of existing TNF inhibitors and have oral bioavailability, can be effectively used as leading anti-inflammatory molecules.
    Type: Application
    Filed: November 5, 2020
    Publication date: January 5, 2023
    Applicants: AJOU UNIVERSITY INDUSTRY-ACADEMIC COOPERATION FOUNDATION, UNIVERSITY-INDUSTRY COOPERATION GROUP OF KYUNG HEE UNIVERSITY
    Inventors: Sang Dun CHOI, Mahesh Chandra PATRA, Nasir JAVAID, Maria BATOOL, Dae-Hyun HAHM
  • Patent number: 11543540
    Abstract: Provided is a method and apparatus for selecting an airborne position reference node. A weight center coordinate of the repeaters is calculated by using position coordinates of repeaters, a plane having a vector connecting the weight center coordinate and a position coordinate of a user as a normal vector is determined, and the position coordinates of the repeaters are orthographically projected onto the plane. A certain number of repeaters located farthest from the weight center coordinate of the repeaters are selected to be airborne position reference nodes, on the basis of the orthographically projected coordinates of the repeaters and the weight center coordinate.
    Type: Grant
    Filed: August 25, 2020
    Date of Patent: January 3, 2023
    Assignees: AGENCY FOR DEFENSE DEVELOPMENT, AJOU UNIVERSITY INDUSTRY-ACADEMIC COOPERATION FOUNDATION
    Inventors: Jae Sung Lim, Ho Ki Baek, Jin Seok Lee, Kyung Woo Kim, Jae Hyun Ham
  • Publication number: 20220409775
    Abstract: The present invention relates to an injectable hydrogel composition having the recruitment of endogenous progenitors or stem cells and the induction of vascular differentiation of recruited cells, and more specifically to an injectable hydrogel composition having the recruitment of endogenous progenitors or stem cells and the induction of vascular differentiation of recruited cells, which consists of: a first solution including anionic hyaluronic acid into which a vascular differentiation inducing factor is introduced; and a second solution including a cationic material, wherein a stem cell recruitment factor is further included in the first solution and/or the second solution, and wherein a hydrogel is formed by electrostatic interaction.
    Type: Application
    Filed: November 17, 2020
    Publication date: December 29, 2022
    Applicant: Ajou University Industry-Academic Cooperation Foundation
    Inventors: Moon Suk KIM, Seung Hun PARK
  • Patent number: 11534473
    Abstract: A composition for preventing or treating hearing loss, containing a Vitis vinifera leaf extract as an active ingredient, is disclosed. A pharmaceutical composition for preventing or treating hearing loss, containing the extract (a Vitis vinifera leaf extract) as an active ingredient, protects auditory hair cells in the cochlea and spiral ganglion cells from damage caused by noise and the like and effectively reduces the hearing threshold measured in the auditory nerves, thereby being usable as an agent for preventing or treating hearing loss.
    Type: Grant
    Filed: May 30, 2018
    Date of Patent: December 27, 2022
    Assignee: AJOU UNIVERSITY INDUSTRY-ACADEMIC COOPERATION FOUNDATION
    Inventors: Yun-Hoon Choung, Young Sun Kim, Young-Joon Park
  • Publication number: 20220403030
    Abstract: The present invention relates to a composition, comprising COTL1 as an active ingredient, for diagnosis of a bone disease or obesity. Downregulation of the expression of the COTL1 protein or a gene thereof inhibits the differentiation activity of osteoclasts to reinforce bone density, compared to a normal control, and to increase factors that induce articular inflammation and cartilage degeneration, causing a bone disease such as osteosclerosis or osteoarthritis. Thus, COTL1 protein or a gene coding therefor can be used for diagnosing, preventing, or treating a bone disease such as osteosclerosis or osteoarthritis. In addition, downregulation of the expression of COTL1 protein or a gene coding therefor exhibits an excellent effect of treating obesity by reducing body weight and body fat mass in high-fat diet obesity mouse models and suppressing hepatic fat accumulation and adipocyte sizes and can be used for diagnosing obesity.
    Type: Application
    Filed: November 19, 2020
    Publication date: December 22, 2022
    Applicant: AJOU UNIVERSITY INDUSTRY-ACADEMIC COOPERATION FOUNDATION
    Inventors: Seon Yong JEONG, Eunkuk PARK, Changgun LEE
  • Publication number: 20220407002
    Abstract: Disclosed is a resistive switching element. The resistive switching element includes a first oxide layer and a second oxide layer stacked one on top of the other such that an interface is present therebetween, wherein the first oxide layer and the second oxide layer are made of different metal oxides; two-dimensional electron gas (2DEG) present in the interface between the first oxide layer and the second oxide layer and functioning as an inactive electrode; and an active electrode disposed on the second oxide layer, wherein when a positive bias is applied to the active electrode, an electric field is generated between the active electrode and the two-dimensional electron gas, such that the second oxide layer is subjected to the electric field, and active metal ions from the active electrode are injected into the second oxide layer. The resistive switching element realizes highly uniform resistive switching operation.
    Type: Application
    Filed: September 17, 2020
    Publication date: December 22, 2022
    Applicants: AJOU UNIVERSITY INDUSTRY-ACADEMIC COOPERATION FOUNDATION, INDUSTRY-UNIVERSITY COOPERATION FOUNDATION HANYANG UNIVERSITY ERICA CAMPUS
    Inventors: Sang Woon LEE, Tae Joo PARK, Hae Jun JUNG, Sung Min KIM, Hye Ju KIM, Seong Hwan KIM
  • Publication number: 20220398865
    Abstract: Provided are a device and method for human parsing. The method includes receiving at least one piece of image data and ground truth values for human parsing, generating a height distribution map and a width distribution map for the image data, acquiring attention maps and scaled feature maps for each of a height and a width of the image data using the distribution maps, calculating a distribution loss rate by concatenating the scaled feature maps, acquiring an improved feature map on the basis of the calculated distribution loss rate, and performing human parsing on an object included in the image data using the improved feature map.
    Type: Application
    Filed: June 13, 2022
    Publication date: December 15, 2022
    Applicant: AJOU UNIVERSITY INDUSTRY-ACADEMIC COOPERATION FOUNDATION
    Inventors: Won Jun HWANG, Kun Liang LIU
  • Publication number: 20220395552
    Abstract: The present invention relates to a composition for inhibiting the toxicity with respect to nanoparticles and particulate matters generated from the environment. Since it has been confirmed that a decrease in intracellular ATP, a decrease in cell viability, inflammation-induced morphological changes in cells and cell activation, which are induced by nanoparticles or environmentally-derived particulate matters, are inhibited by means of the composition of the present invention, the composition may be utilized as a reducing substance for the toxicity of nanoparticles and particulate matters.
    Type: Application
    Filed: August 12, 2020
    Publication date: December 15, 2022
    Applicant: AJOU UNIVERSITY INDUSTRY-ACADEMIC COOPERATION FOUNDATION
    Inventors: Gwang LEE, Tae-Hwan SHIN, Yup KANG, Jong-Young KWAK, Dayeon LEE
  • Publication number: 20220392094
    Abstract: Disclosed is a stereo matching method of images performed by a system implemented by a computer, including the steps of: receiving a pair of images obtained at different time points; generating a feature map by extracting features of each pixel of the pair of images; generating sequentially cost volumes for partial time points based on the feature map and generating a feature map for the entire disparity by fusing the cost volumes using 2D convolution; and generating a final disparity map by refining the generated feature map.
    Type: Application
    Filed: May 12, 2022
    Publication date: December 8, 2022
    Applicant: Ajou University Industry-Academic Cooperation Foundation
    Inventors: Yong Seok Heo, Jae Cheol Jeong, Su Yeon Jeon
  • Patent number: 11519853
    Abstract: Provided are a method of evaluating biogas power generation suitability performed by a biogas power generation suitability evaluation server including a processor and a memory, the method comprises extracting, from satellite image data of an evaluation target area, an area corresponding to the evaluation target area, calculating a size of biogas generation facilities included in the evaluation target area based on the extracted area, calculating a biogas concentration of the evaluation target area from the satellite image data and evaluating the biogas power generation suitability based on the size of the biogas generation facilities and the biogas concentration of the evaluation target area, wherein the calculating of the biogas concentration of the evaluation target area comprises calculating an average value of biogas concentrations of area corresponding to the evaluation target area, and the evaluating of the biogas power generation suitability comprises calculating, based on the size of the biogas genera
    Type: Grant
    Filed: April 1, 2022
    Date of Patent: December 6, 2022
    Assignee: AJOU UNIVERSITY INDUSTRY-ACADEMIC COOPERATION FOUNDATION
    Inventors: Ju Young Kang, Jae Hyeong Park, Sang Ho Ahn
  • Publication number: 20220383047
    Abstract: The present invention relates to a method and apparatus for unsupervised domain adaptation, including the steps of generating a first augmented domain associated with a source domain, generating a second augmented domain associated with a target domain, and performing unsupervised domain adaptation by using the first augmented domain and the second augmented domain as a bridge for connecting the source domain and the target domain, and it is possible to apply to other exemplary embodiments.
    Type: Application
    Filed: December 28, 2021
    Publication date: December 1, 2022
    Applicant: AJOU UNIVERSITY INDUSTRY-ACADEMIC COOPERATION FOUNDATION
    Inventors: Won Jun HWANG, Jae Min NA
  • Patent number: 11510853
    Abstract: The present invention is to provide a composition for skin soothing, which is safe from a risk of side effects, and relates to a composition for skin soothing containing a liquid-phase plasma. The liquid-phase plasma of the present invention is obtained by applying plasma as pure energy to a liquid-phase material, and can be used in the skin sensitive to a chemical material without a risk of side effects. Furthermore, the liquid-phase plasma has remarkable effects on the prevention or treatment of dermatitis or photo-aging due to ultraviolet light, and thus is expected to be greatly used in beauty care and mechanical fields.
    Type: Grant
    Filed: September 17, 2018
    Date of Patent: November 29, 2022
    Assignee: AJOU UNIVERSITY INDUSTRY-ACADEMIC COOPERATION FOUNDATION
    Inventors: Chul Ho Kim, Kyoungwon Jung
  • Patent number: 11510911
    Abstract: The present invention relates to a method for predicting susceptibility to sorafenib treatment by using an SULF2 gene, and a composition for treatment of sorafenib-resistant cancer using the SULF2 expression inhibition. The method for predicting susceptibility to sorafenib treatment by using the SULF2 gene according to the present invention can enable achievement of an optimal therapeutic effect by administering a drug suitable for cancer patients, and the composition for treatment of sorafenib-resistant cancer using the SULF2 inhibition has a very excellent anticancer treatment effect.
    Type: Grant
    Filed: March 20, 2018
    Date of Patent: November 29, 2022
    Assignee: AJOU UNIVERSITY INDUSTRY-ACADEMIC COOPERATION FOUNDATION
    Inventors: Hyun Goo Woo, Sarah Yoon, Eun-Ju Lee
  • Patent number: 11493594
    Abstract: The present invention relates to a method and apparatus for TDOA wireless positioning, has an effect of reducing positioning errors by reducing TDOA errors using destructive interference of multiple anchor nodes by dividing four or more anchor nodes into sets of three or more anchor nodes and by estimating a position of a tag node using TDOA of each set, and has an advantage of reducing the size and weight of the tag node since separate hardware is not required.
    Type: Grant
    Filed: January 21, 2021
    Date of Patent: November 8, 2022
    Assignee: AJOU UNIVERSITY INDUSTRY-ACADEMIC COOPERATION FOUNDATION
    Inventors: Young-Bae Ko, Jiwoong Park
  • Patent number: 11493916
    Abstract: A method of operating a moving object on which a drone is mounted includes detecting, by the moving object, occurrence of an event; determining whether to use the drone, on the basis of the detected event; and determining an operation mode, among a first operation mode and a second operation mode, of the drone when the drone is used.
    Type: Grant
    Filed: June 23, 2020
    Date of Patent: November 8, 2022
    Assignees: HYUNDAI MOTOR COMPANY, KIA MOTORS CORPORATION, AJOU UNIVERSITY INDUSTRY-ACADEMIC COOPERATION FOUNDATION
    Inventors: Jae Jun Ha, Ilsoo Yun, Seungkyu Ryu, Sangmin Park, Sungho Park, Harim Jeong, Cheolwoo Kwon, Jiwon Kim, Kiyeon Park
  • Patent number: 11488288
    Abstract: Disclosed are a method and an apparatus for processing a blurred image. The method for processing a blurred image includes the steps of generating a first input feature map and a second input feature map with a feature distribution for blur removal from the blurred image, generating a prediction feature map from the first input feature map by using a self-spatial feature transform (SSFT) module which transforms the feature distribution for blur removal into a feature distribution for face recognition without external information, and generating a deblurred image based on the second input feature map and the prediction feature map.
    Type: Grant
    Filed: May 11, 2022
    Date of Patent: November 1, 2022
    Assignee: AJOU UNIVERSITY INDUSTRY-ACADEMIC COOPERATION FOUNDATION
    Inventors: Yong Seok Heo, Soo Hyun Jung, Tae Bok Lee
  • Publication number: 20220340867
    Abstract: The present invention relates to a method for fabrication of an extracellular matrix-induced self-assembly and to fabrication of an artificial tissue using same. The method for fabrication of an extracellular matrix-induced self-assembly comprise the steps of: (a) decellularizing and powdering a tissue-derived extracellular matrix (ECM); and (b) adding the decellularized extracellular matrix powder to cells and culturing the cells to form a cell-extracellular matrix powder self-assembly. Accordingly, the self-assembly has characteristics similar to those of extracellular matrix tissues and can be fabricated into three-dimensional artificial tissues 1 cm or greater in size, thus finding advantageous applications as a cell therapy product and an artificial tissue implant.
    Type: Application
    Filed: September 17, 2020
    Publication date: October 27, 2022
    Applicant: AJOU UNIVERSITY INDUSTRY-ACADEMIC COOPERATION FOUNDATION
    Inventors: Do Young PARK, Hee Woong YUN
  • Patent number: 11483012
    Abstract: A method for decoding a signal encoded with polar codes by a decoding system is provided. The method comprises receiving, from a transmission system, a signal in which a plurality of cyclic redundancy checks (CRCs) are encoded by the polar codes, the plurality of CRCs being inserted into positions determined based on a plurality of information bits, a number of the plurality of information bits and a total code length, and decoding a code section including bits ranging from a first bit of the signal to a position where a last bit of a first CRC is inserted. The method further comprises re-performing successive cancellation flip decoding for the decoded code section, or determining whether to decode a next code section adjacent to the decoded code section, based on whether a CRC is detected in the decoded code section.
    Type: Grant
    Filed: February 18, 2021
    Date of Patent: October 25, 2022
    Assignee: AJOU UNIVERSITY INDUSTRY-ACADEMIC COOPERATION FOUNDATION
    Inventors: Myung Hoon Sunwoo, Seung Yong Kim
  • Publication number: 20220334105
    Abstract: A bio-substance analysis method using a sensing substrate having a fluid channel is disclosed. The method includes mixing retroreflective particles with a detection solution containing a target bio-substance, wherein a first bio-recognition substance selectively reacting with the target bio-substance is modified on the retroreflective particles; placing the sensing substrate so that a bottom is located under a cover in a direction of gravity; injecting the detection solution containing therein the retroreflective particles into a fluid channel and maintaining the solution in the channel for a first time duration; turning the sensing substrate upside down so that the bottom is located above the cover in the direction of gravity and maintaining the sensing substrate in the turned state for a second time duration; irradiating light into the fluid channel through the bottom; and generating and analyzing an image based on light retroreflected from the retroreflective particles.
    Type: Application
    Filed: November 26, 2019
    Publication date: October 20, 2022
    Applicant: AJOU UNIVERSITY INDUSTRY-ACADEMIC COOPERATION FOUNDATION
    Inventors: Hyun Chul YOON, Ka Ram KIM, Hyeong Jin CHUN, Jae Ho KIM