Patents Assigned to Ajou University Industry-Academic Cooperation Foundation
  • Publication number: 20220065875
    Abstract: A biomarker composition for diagnosing degenerative brain diseases comprises TB (TRAF-6 binding) domain in SQSTM1/p62 protein. The TB (TRAF-6 binding) domain in the SQSTM1/p62 protein directly binds to the tau protein to remove the tau protein, and thus the exposure of the TB domain may be usefully utilized in diagnosing and/or treating degenerative brain diseases in degenerative brain diseases in which tauopathy is observed.
    Type: Application
    Filed: February 7, 2020
    Publication date: March 3, 2022
    Applicant: AJOU UNIVERSITY INDUSTRY-ACADEMIC COOPERATION FOUNDATION
    Inventor: Sun Ah PARK
  • Patent number: 11260062
    Abstract: Provided is a composition for treating or ameliorating lung cancer including a glucocorticoid-based compound, a glucocorticoid-based compound and an mTOR inhibitor, or a glucocorticoid-based compound and an AMPK inhibitor as an active ingredient. The glucocorticoid-based compounds inhibit the growth of cancer cells by suppressing NRF2 in KEAP1 mutant lung cancer or KEAP1 and LKB1 mutant lung cancer, and exhibit a more potent anticancer effect when used in combination with the mTOR inhibitor, and thus the compounds can be effectively used as anticancer agents for mutant lung cancer. Further, the glucocorticoid-based compounds exhibit a strong anticancer synergistic effect in a low nutritional state when treated in combination with an AMPK inhibitor in KEAP1 and LKB1 normal lung cancer, and thus the compounds can also be used as an anticancer agent for KEAP1 normal lung cancer.
    Type: Grant
    Filed: November 2, 2016
    Date of Patent: March 1, 2022
    Assignee: AJOU UNIVERSITY INDUSTRY-ACADEMIC COOPERATION FOUNDATION
    Inventor: Sang-Min Jeon
  • Publication number: 20220052755
    Abstract: The method for compensating a boresight error in a low earth orbit (LEO) satellite antenna according to the present disclosure comprising the steps of: converting a communication point of the LEO satellite and the location of the ground station into the geocentric coordinate system, and setting an incidence angle of the electromagnetic wave radiated from the antenna of the LEO satellite; calculating the measured meteorological condition as a meteorological condition at a specific altitude interval; calculating the meteorological conditions respectively as an effective refractive index; dividing the atmosphere into layers at specific altitude intervals, and calculating an arrival coordinate of the electromagnetic wave for which the atmospheric environment is considered; when the error between the location of the ground station and the arrival coordinate of the electromagnetic wave is less than a target error, deciding the compensating angle for the incidence angle of the electromagnetic wave.
    Type: Application
    Filed: June 16, 2021
    Publication date: February 17, 2022
    Applicant: AJOU UNIVERSITY INDUSTRY-ACADEMIC COOPERATION FOUNDATION
    Inventors: Yong Bae Park, Chang Seong Kim
  • Patent number: 11246885
    Abstract: The present invention relates to a method of preventing or treating keloids using a liquid plasma. A liquid plasma according to the present invention is remarkably effective in inhibiting the generation and proliferation of keloids, thus being expected to be greatly utilized for the prevention and treatment of keloids.
    Type: Grant
    Filed: August 23, 2018
    Date of Patent: February 15, 2022
    Assignee: AJOU UNIVERSITY INDUSTRY-ACADEMIC COOPERATION FOUNDATION
    Inventors: Chul Ho Kim, Sung Un Kang
  • Publication number: 20220033265
    Abstract: The present embodiments relate to a method for manufacturing a two-dimensional material using a top-down method, the method includes the steps of preparing a bulk crystal, forming a metal layer on the bulk crystal, and then attaching a thermal release tape on the metal layer, exfoliating a two-dimensional material to which the metal layer and the thermal release tape have been attached from the bulk crystal, transferring the two-dimensional material to which the metal layer and the thermal release tape have been attached onto a substrate, and removing the thermal release tape and the metal layer from the substrate onto which the two-dimensional material has been transferred.
    Type: Application
    Filed: July 29, 2021
    Publication date: February 3, 2022
    Applicant: AJOU UNIVERSITY INDUSTRY-ACADEMIC COOPERATION FOUNDATION
    Inventors: Jaehyun LEE, Jiyun MOON
  • Publication number: 20220036544
    Abstract: The present invention relates to a breast image analysis method with four mammogram images which are input to a convolutional neural network as one input and a system therefor and the system includes an image receiving unit which receives four mammogram images; an image size adjusting unit which adjusts a size of a mammogram image received from the image receiving unit; a preprocessing unit which performs preprocessing on the mammogram image adjusted by the image size adjusting unit; a convolutional neural network (CNN)-based CNN learning unit which generates learning information by learning the mammogram image preprocessed by the preprocessing unit; and a CNN inference unit which receives the learning information learned from the CNN learning unit and a mammogram image to be classified from the image receiving unit to diagnose a breast abnormality.
    Type: Application
    Filed: August 22, 2019
    Publication date: February 3, 2022
    Applicant: AJOU UNIVERSITY INDUSTRY-ACADEMIC COOPERATION FOUNDATION
    Inventors: Myung Hoon SUNWOO, Ji Hoon BAE
  • Publication number: 20220028792
    Abstract: A semiconductor interconnect and an electrode for semiconductor devices may include a thin film including a multielement compound represented by Formula 1 and having a thickness equal to or less than about 50 nm, a grain size (A) to thickness (B) ratio (A/B) equal to or greater than about 1.2, and a resistivity equal to or less than about 200 ??·cm: Mn+1AXn??Formula 1 In Formula 1, M, A, X, and n are as described in the specification.
    Type: Application
    Filed: July 23, 2021
    Publication date: January 27, 2022
    Applicants: Samsung Electronics Co., Ltd., AJOU UNIVERSITY INDUSTRY-ACADEMIC COOPERATION FOUNDATION
    Inventors: Youngjae KANG, SangWoon LEE, Joungeun YOO, Duseop YOON
  • Publication number: 20220000943
    Abstract: A pharmaceutical composition or a health functional food composition for preventing or treating Behcet's disease have Tetragenococcus halophilus, a culture thereof or a lysate thereof. In addition, a pharmaceutical composition or a health functional food composition for preventing or treating a herpes simplex virus infection have Tetragenococcus halophilus, a culture thereof or a lysate thereof. The composition may further include a prebiotic compound. The Tetragenococcus halophilus produces lactate, and the lactate can be converted into short-chain fatty acids such as butyrate in the body, can control the expression of activating molecules of dendritic cells, and can effectively prevent or treat Behcet's disease or herpes simplex virus infection.
    Type: Application
    Filed: October 1, 2019
    Publication date: January 6, 2022
    Applicant: AJOU UNIVERSITY INDUSTRY-ACADEMIC COOPERATION FOUNDATION
    Inventor: Seong Hyang SOHN
  • Publication number: 20220003787
    Abstract: Provided are a composition for diagnosing Alzheimer's dementia, the composition including an agent for measuring levels of mRNAs of one or more genes selected from the group consisting of neurotrimin (NTM), peptidylglycine-?-amidating monooxygenase (PAM), receptor-type tyrosine-protein phosphatase N2 (PTPRN2), opioid-binding protein/cell adhesion molecule (OPCML), 14-3-3 protein ?/? (YWHAZ), chromogranin-A (CHGA), and secretogranin-1 (CHGB), or levels of proteins expressed therefrom; a kit for diagnosing Alzheimer's dementia, the kit including the composition; and a method of providing information for the diagnosis of Alzheimer's dementia, the method including the steps of measuring the levels of mRNAs of the genes or the levels of proteins expressed therefrom, and comparing the measured levels with those measured in a sample isolated from a normal individual.
    Type: Application
    Filed: September 11, 2019
    Publication date: January 6, 2022
    Applicant: AJOU UNIVERSITY INDUSTRY-ACADEMIC COOPERATION FOUNDATION
    Inventor: Sun Ah PARK
  • Patent number: 11215690
    Abstract: The present invention provides an augmented reality service providing device, including: a sensing unit to photograph an object and to measure a current position of a mobile terminal; a communication unit to measure a communication distance between the mobile terminal and the object; a control unit to control to repeat a plurality of times the measurement of the current position and the communication distance while the mobile terminal is moving; a calculation unit to calculate an estimated position of the object based on the current position and the communication distance measured repeatedly a plurality of times; and a display unit to display virtual information on the object on the estimated position of the object.
    Type: Grant
    Filed: January 14, 2021
    Date of Patent: January 4, 2022
    Assignee: AJOU UNIVERSITY INDUSTRY-ACADEMIC COOPERATION FOUNDATION
    Inventors: Young-Bae Ko, Hong Beom Choi
  • Publication number: 20210403580
    Abstract: An antibody or antigen-binding fragment thereof, which binds with a high pM-level affinity to a human IL-4 receptor alpha chain that is a human IL-4 receptor, is provided. The antibody or antigen-binding fragment has a different epitope and a different antigen dissociation rate than existing antibodies. A nucleic acid encoding the antibody or antigen-binding fragment thereof, a vector including the nucleic acid, a cell transformed with the vector, a method for producing the antibody or antigen-binding fragment thereof, a conjugate comprising the antibody or antigen-binding fragment thereof, a composition for preventing or treating inflammatory diseases, and a composition for diagnosing inflammatory diseases are disclosed.
    Type: Application
    Filed: November 7, 2019
    Publication date: December 30, 2021
    Applicant: Ajou University Industry-Academic Cooperation Foundation
    Inventors: Yong Sung KIM, Hae-Sim PARK, Jung Eun KIM, Keunok JUNG
  • Patent number: 11206969
    Abstract: Provided is a method for tracking a position of a capsule endoscope including: receiving, by an apparatus for tracking a position of a capsule endoscope, an image captured by the capsule endoscope; distinguishing, by the apparatus for tracking a position of a capsule endoscope, a gastrointestinal tract junction from the image using a machine-learned classification model based on the gastrointestinal tract junctions; and tracking, by the apparatus for tracking a position of a capsule endoscope, the position of the capsule endoscope based on the distinguished gastrointestinal tract junctions.
    Type: Grant
    Filed: August 22, 2018
    Date of Patent: December 28, 2021
    Assignee: AJOU UNIVERSITY INDUSTRY-ACADEMIC COOPERATION FOUNDATION
    Inventors: Jung Won Lee, Ye Seul Park, Gyu Bon Hwang
  • Publication number: 20210395826
    Abstract: The present invention relates to a single nucleotide polymorphism marker for precocious puberty diagnosis or treatment prognosis prediction for the disease, and a use thereof. In the present invention, the DNA of 700 girl patients of precocious puberty is processed on a microarray chip containing a total of 8,754,887 SNP probes so that SNP genotype data is obtained, and 23 SNPs related to the risk of developing precocious puberty are discovered by means of genome-wide association analysis so that the SNPs can be used for precocious puberty diagnosis or treatment prognosis prediction, early diagnosis of precocious puberty can be conveniently and rapidly carried out, and the prediction of treatment effects and prognosis can be carried, and thus the present invention can be effectively used in a personalized treatment.
    Type: Application
    Filed: August 6, 2021
    Publication date: December 23, 2021
    Applicant: AJOU UNIVERSITY INDUSTRY-ACADEMIC COOPERATION FOUNDATION
    Inventors: Jin Soon HWANG, Seon Yong JEONG, Hae Sang LEE, Eun Young KIM
  • Publication number: 20210387166
    Abstract: A catalyst with a core-shell structure for methane oxidation, a method of preparing the catalyst, and a method of methane oxidation using the catalyst are disclosed. The catalyst includes a core structure consisting of a nano-support and core nanoparticles; and a shell coating layer coated on the core structure in which the core nanoparticles have a particle diameter smaller than that of the nano-support and are coated on the nano-support to form a core structure. The catalyst has excellent thermal stability during methane oxidation reaction at high temperature and an effect of increasing methane conversion and formaldehyde selectivity.
    Type: Application
    Filed: July 26, 2019
    Publication date: December 16, 2021
    Applicants: UNIST (Ulsan National Institute of Science and Technology), AJOU UNIVERSITY INDUSTRY-ACADEMIC COOPERATION FOUNDATION
    Inventors: Kwang Jin AN, Eun Duck PARK, Eui Seob YANG
  • Patent number: 11195014
    Abstract: A waterproof paint state determining method of a building using a satellite imagery according to an exemplary embodiment of the present disclosure includes receiving search information including information about a location in which a waterproof paint application state of a rooftop of a building is to be measured from a user; searching a search satellite imagery which is at least one satellite imagery corresponding to the search information from a satellite imagery DB including a plurality of satellite imagery data; detecting a rooftop area which is a waterproof paint application area of at least one building corresponding to the search information from the search satellite imagery, using a convolutional neural network (CNN) technique; and calculating a state index which is an index indicating a waterproof paint application state of at least one building, based on reference color information and color information of the rooftop area.
    Type: Grant
    Filed: April 13, 2021
    Date of Patent: December 7, 2021
    Assignee: AJOU UNIVERSITY INDUSTRY-ACADEMIC COOPERATION FOUNDATION
    Inventors: Ju Young Kang, Jae Hyeong Park, Sang Ho Ahn
  • Publication number: 20210375619
    Abstract: A method for producing a transition metal dichalcogenide-graphene heterojunction composite, the method includes: transferring a graphene onto a flexible substrate; depositing a transition metal layer on the flexible substrate onto which the graphene has been transferred; and injecting a gas containing plasma-treated sulfur (S) onto the flexible substrate onto which the transition metal layer has been deposited, is disclosed.
    Type: Application
    Filed: May 25, 2021
    Publication date: December 2, 2021
    Applicants: Research & Business Foundation Sungkyunkwan University, Ajou University Industry-Academic Cooperation Foundation
    Inventors: Taesung KIM, Jaehyun LEE, Hyunho SEOK, Hyeong U KIM
  • Publication number: 20210371570
    Abstract: The present invention relates to a method for preparing a polyolefin block copolymer, the method comprising: a first step of coordination polymerization of an olefin monomer with a transition metal catalyst in the presence of organozinc; and a second step of continuously adding a diacyl peroxide compound to perform polymerization, and to a polyolefin block copolymer prepared therefrom.
    Type: Application
    Filed: December 21, 2018
    Publication date: December 2, 2021
    Applicant: AJOU UNIVERSITY INDUSTRY-ACADEMIC COOPERATION FOUNDATION
    Inventors: Bun Yeoul LEE, Sung Dong KIM, Su Jin GWON, Tae Hee KIM
  • Patent number: 11185607
    Abstract: A preparation method of calcium peroxide-mediated in situ crosslinkable hydrogel as a sustained oxygen-generating matrix, includes: a) reacting a natural or a synthetic polymer with Traut's reagent (TR) in a solvent, and synthesizing a polymer derivative having thiol group in backbone of the polymer derivative; and b) mixing and reacting a solution of the polymer derivative having thiol group with calcium peroxide (CaO2), and thereby forming a hydrogel, wherein in the step b), disulfide bonds (—S—S) are induced between backbones of the polymer derivative having thiol group attached by decomposition of calcium peroxide (CaO2), and thereby in situ crosslinking is formed.
    Type: Grant
    Filed: August 3, 2017
    Date of Patent: November 30, 2021
    Assignees: INCHEON UNIVERSITY INDUSTRY ACADEMIC COOPERATION FOUNDATION, AJOU UNIVERSITY INDUSTRY-ACADEMIC COOPERATION FOUNDATION
    Inventors: Kyung Min Park, Ki Dong Park, Su Jin Park
  • Patent number: 11187896
    Abstract: An image display device includes a display device configured to modulate light to form an image, a light transmitting unit that transmits the image formed by the display device to eyes of a viewer and includes a focusing member, a driving unit that applies a driving force to a central position of the display device in a direction to change a distance between the display device and the light transmitting unit in the direction, a processor configured to control the display device, a connector disposed between one end of the display device and the processor, the connector connecting the display device to the processor, and a tilt prevention unit that applies an elastic force in the direction to the one end of the display device and to another end of the display device opposite to the one end.
    Type: Grant
    Filed: March 31, 2020
    Date of Patent: November 30, 2021
    Assignees: SAMSUNG ELECTRONICS CO., LTD., AJOU UNIVERSITY INDUSTRY-ACADEMIC COOPERATION FOUNDATION
    Inventors: Bongsu Shin, Jesung Koh, Dongjin Kim, Geeyoung Sung, Hongseok Lee
  • Patent number: 11186612
    Abstract: A substance P analog having a progenitor cell or stem cell recruiting activity and a method of recruiting progenitor cells or stem cells using the substance P analog are disclosed. The substance P analog has an effect of recruiting endogenous progenitor cells or stem cells to a wound or disease-occurring site. Thus, the disclosure also describes its use in recruiting progenitor cells or stem cells and a method of regenerating or treating a damaged organ or tissue, or a method of healing a wound.
    Type: Grant
    Filed: April 24, 2020
    Date of Patent: November 30, 2021
    Assignee: AJOU UNIVERSITY INDUSTRY-ACADEMIC COOPERATION FOUNDATION
    Inventors: Moon Suk Kim, Sang Dun Choi, Seung Hun Park, Masaud Shah