Abstract: A heterodimeric Fc-fused protein and a pharmaceutical composition comprising the heterodimeric Fc-fused protein are disclosed. The heterodimeric Fc-fused protein includes first and second Fc regions of an immunoglobulin heavy chain constant region (Fc) pair and in which IL-21 is bound to at least one of the N-terminus or the C-terminus of the first Fc region and/or the second Fc region, wherein CH3 domains of the first Fc region and the second Fc region are mutated such that the formation of a heterodimer is promoted. When the heterodimeric Fc-fused protein is used, an in vivo half-life of IL-21 included in the heterodimeric Fc-fused protein may be significantly increased.

Abstract: The present invention provides a composition for regenerating nucleus pulposus and a composition for regenerating an intervertebral disc tissue, each comprising fetal cartilage tissue-derived cells and a fetal cartilage tissue-derived extracellular matrix as active ingredients, and a pharmaceutical composition comprising the composition as an active ingredient for preventing or treating a vertebral disease. Simulating features of the nucleus pulposus, such as compression and tensile strength, the composition for regenerating nucleus pulposus can be regenerated into a tissue similar thereto. The composition for regenerating nucleus pulposus can be implanted into an intervertebral disc to restore an injured intervertebral disc tissue. Hence, the pharmaceutical composition comprising same for preventing or treating a vertebral disease can be used as a basic therapeutic agent for a vertebral disease such as a herniated intervertebral disc.

Abstract: Provided are a drone taxi system based on multi-agent reinforcement learning and a drone taxi operation method using the same. The drone taxi system includes a plurality of drone taxies configured to receive call information including departure point information and destination information from passenger terminals present within a certain range and a control server configured to receive call information of passengers from each drone taxi, select a candidate passenger depending on whether a passenger is present, generate travel route information of each drone taxi from drone state information of the plurality of drone taxies through multi-agent reinforcement learning, and transmit the travel route information to the drone taxi.

Abstract: There are disclosed an apparatus and method for processing images.

Abstract: An apparatus for predicting a concurrent lane change of multiple vehicles to prevent or minimize collision, and a vehicle using the same. The apparatus includes a subject vehicle state estimator for estimating a state of a subject vehicle based on subject vehicle information and surrounding lane state information, a surrounding vehicle state estimator for estimating a state of a surrounding vehicle based on the subject vehicle state information and surrounding vehicle information, a lane state estimator for estimating a state of a surrounding lane based on the estimated subject vehicle state information and surrounding lane information, and a lane change predictor for predicting concurrent lane change of the subject vehicle and the surrounding vehicle based on the estimated subject vehicle state information, the estimated surrounding vehicle state information and the estimated surrounding lane state information.

Abstract: An operating method of a computing device operated by at least one processor includes collecting traffic packets; extracting particular field data from the traffic packets, transforming the extracted particular field data to a vector with a reduced dimension for each traffic packet, and creating training data with the vector for each traffic packet; training a traffic prediction model with the training data, the traffic prediction model predicting from an input traffic packet a next input traffic packet and whether the next input traffic packet is abnormal; and predicting with the trained traffic prediction model a frequency of abnormal traffic packets to be input, and outputting an abnormal traffic warning by comparing the predicted frequency and a threshold.

Abstract: A multi-degree of freedom (DOF) moving stage includes: an end-effector; three driven links pivotably connected to the end-effector at angular intervals from each other; three driving links pivotably connected to the three driven links, respectively; and three actuators configured to drive the three driving links, respectively. Each of the three driven links includes first to fourth arms arranged at intervals; and a flexible member that connects the first to fourth arms to each other in a parallelogram shape across the intervals and forms pivotable joints at the intervals.

Abstract: The present invention provides a microneedle stamp device for injecting liquid medicine; a carboxy cartridge provided in the main body portion; a liquid medicine storage portion provided outside the main body portion and connected to the carboxy cartridge; a needle portion connected to the carboxy cartridge and the liquid medicine storage portion; a power portion provided in the grip; a connection portion configured to connect the carboxy cartridge to the needle portion; and a contact plate provided at the contact end of the main body portion, wherein, when the contact plate comes into contact with the skin of the treatment subject, the contact plate slidingly moves to the inside of the contact end to apply an external force to the power portion to operate the power portion to supply the liquid medicine and the carbon dioxide to the needle portion.

Abstract: A compound of Chemical Formula 1 or a pharmaceutically acceptable salt thereof is disclosed. The compound inhibits a toll-like receptor (TLR) signaling pathway. A composition containing the compound and uses thereof are disclosed.

Abstract: A polar code decoding apparatus according to an embodiment includes a divider configured to generate a decoding tree in which a plurality of nodes including one or more critical sets for a polar-encoded codeword are formed in a hierarchical structure, and divide the decoding tree into one or more partitions, each partition equally including lowest nodes of the decoding tree, a determiner configured to determine a memory size for storing a primary decoding result based on a specific partition, the specific partition being selected from among the one or more partitions based on the number of critical sets included in each partition, and a decoder configured to decode the codeword primarily by using a successive cancellation (SC) decoding technique.

Abstract: Provided is an image display device including a display element configured to modulate light to form an image; a light transfer unit configured to transmit the image formed by the display element to eyes of an observer, the light transfer unit comprising a focusing member; and a driver configured to drive the display element to change a position of the display element, the driver including: a first actuator comprising a deformable wire; a housing that fixes a first end and a second end of the deformable wire; and an operating structure through which the deformable wire is routed, wherein the operating structure is configured move the display element in a first direction in conjunction with a length variation of the deformable wire, and the operating structure includes an elastic structure configured to prevent tilt with respect to an axis in the first direction.

Abstract: The present invention relates to a pharmaceutical composition for preventing or treating an angiogenesis-related ocular disease comprising an inhibitor of MCT expression or MCT activity as an active ingredient, and it can effectively prevent or treat an angiogenesis-related ocular disease without affecting the normal function of VEGF required for maintaining homeostasis of choriocapillary and visual cells, by specifically inhibiting only VEGF secreted by macrophages, different from conventional treatment.

Abstract: A real-time scheduling apparatus and method for suppressing battery aging of a satellite system are disclosed. A real-time scheduling method for suppressing battery aging of a satellite system according to an exemplary embodiment of the present disclosure may include acquiring task information including a request period and an execution time of each of a plurality of tasks which is performed in the satellite system; determining an execution limit range and an execution order for each of the plurality of tasks which satisfies a predetermined real-time constraint based on the task information; and determining an optimal execution timing within the execution limit range of each of the plurality of tasks, based on the execution order and consumed current information of each of the plurality of tasks.

Abstract: The present application relates to a method and apparatus for digital forensic corresponding to an IoT (Internet of Things) terminal, the method including: performing, by an electronic device, an analysis of an Internet of Things (IoT) terminal to which digital forensics is to be performed; selecting an injection method of injecting, by the electronic device, a certificate into the IoT terminal; injecting, by the electronic device, a certificate into at least one of the IoT terminal, the electronic device, and a portable device communicating with the IoT terminal using the selected injection method; and verifying, by the electronic device, data stored in a cloud server communicating with the IoT terminal based on the injected certificate, and can also be applied to other embodiment.

Abstract: A method of preparing a mouse model of herpes using a herpes simplex virus and hydrocortisone, and a mouse model of herpes prepared the method are disclosed. When the preparation method is used, an animal model in which the symptoms of herpes clearly appear can be prepared, and thus the animal model can be widely used in the development of therapeutic agents for herpes simplex virus infection. A use of the mouse model in screening and developing a candidate therapeutic agent is also disclosed.

Abstract: The present invention relates to a method and apparatus for tracing a fault of a collaborative robot, including the steps of setting, by an electronic device, a basic index which serves as an analysis criterion of operational data generated by the collaborative robot, setting, by the electronic device, an analysis index for analyzing the operational data, receiving, by the electronic device, a plurality of operational data from the collaborative robot, and tracing, by the electronic device, a fault generated in at least one of the plurality of operational data using the basic index and the analysis index, and the application to other exemplary embodiments is possible.

Abstract: An apparatus for inserting an error correction code according to an embodiment includes an identifier configured to identify a plurality of critical sets included in a codeword generated using a polar code, based on the number of information bits and a total code length of the codeword, a divider configured to divide the codeword into a plurality of partitions, and an inserter configured to insert an error correction code into each of the divided partitions based on a distribution position of each of the plurality of critical sets.

Abstract: A device for identifying a road surface includes: storage for storing a deep learning-based road surface model; and a controller configured to identify a type of a road surface on which a vehicle is currently traveling, using the road surface model. The device for identifying a road surface can identify a type of a road surface on which the vehicle is traveling based on deep learning and control the terrain mode of the vehicle based on the identified type of the road surface. The type of the road surface on which the vehicle is traveling may be identified with a high accuracy and an optimal terrain mode may be set, thereby improving not only travel stability but also riding comfort of the vehicle.

Abstract: A convolution method for high speed deep learning according to the present invention includes (a) a step in which a feature map receiving unit of the convolution system receives a feature map configured by N channels; (b) a step in which a main controller of the convolution system selects a “0”-th channel from the feature map configured by N channels; (c) a step in which the main controller confirms a coordinate in which x, y coordinate is “0”, from the feature map of the “0”-th channel; (d) a coarse step in which a convolution calculating unit of the convolution system performs a convolution operation and a rectified linear unit (ReLU) operation while shifting by 2 in a horizontal direction and a vertical direction in the feature map; (e) a step in which the channel switching unit of the convolution system switches the channel to a subsequent channel when the coarse step is completed for the feature map of the “0”-th channel; (g) a step in which the main controller determines whether the switched channel is

Abstract: An apparatus for generating an HDR image includes an input image generator that generates a first image and a second image and an HDR image generator that generates a high dynamic range (HDR) in which a dynamic range of an original image is extended from the first image and the second image using a pre-trained model including a first neural network, a second neural network, and a third neural network, in which the first neural network is pre-trained to output a third image, the second neural network is pre-trained to output a fourth image and the third neural network is pre-trained to generate the HDR image based on the third image and the fourth image.