Patents Assigned to ALBERT-LUDWIG-UNIVERSITAET FREIBURG
  • Publication number: 20130068156
    Abstract: A method for growing II-VI semiconductor crystals and II-VI semiconductor layers as well as crystals and layers of their ternary or quaternary compounds from the liquid or gas phase is proposed. To this end, the solid starting materials are introduced into a growing chamber for the growing of crystals. Inside the growing chamber, carbon monoxide is supplied by way of reducing agent. At least certain zones of the growing chamber are heated to a temperature at which a first-order phase transition of the starting materials takes place and the starting materials pass into the liquid or gas phase. The starting materials are then cooled down accompanied by the formation of a semiconductor crystal or semiconductor layer, again with a first-order phase transition taking place. The oxygen present in the growing chamber is bound by the carbon monoxide and the formation of an oxide layer at the phase boundary of the growing semiconductor crystal or semiconductor layer is prevented.
    Type: Application
    Filed: May 30, 2011
    Publication date: March 21, 2013
    Applicant: Albert-Ludwigs-Universitaet Freiburg
    Inventor: Alex Fauler
  • Patent number: 8338146
    Abstract: A process for preparing optically active alcohols of the formula Ia or Ib in which R1,R2 are alkyl, alkenyl, aryl, or alkylaryl groups which may in turn be substituted one or more times by alkyl, halogen, SH, SR2, OH, OR2, NO2, CN, CO, COOR2, NR2R3 or NR2R3R4+X, where R2, R3 and R4 are independently of one another H or a lower alkyl or lower alkoxy radical, and X?is a counter ion, with the proviso that R1 is not equal to R2, by reducing the corresponding ketone, where the reduction is carried out with a dehydrogenase having the polypeptide sequence of SEQ ID NO: 2 or NO: 4, or with a polypeptide sequence in which up to 25% of the amino acid residues are altered by comparison with SEQ ID NO: 2 or NO: 4 by deletion, insertion, substitution or a combination thereof.
    Type: Grant
    Filed: June 16, 2008
    Date of Patent: December 25, 2012
    Assignees: BASF SE, Albert-Ludwigs-Universitaet Freiburg, Max-Planck-Gesellschaft zur Förderung der Wissenschaften e.V.
    Inventors: Michael Breuer, Ralf Rabus, Johann Heider
  • Publication number: 20120314528
    Abstract: A device for producing a dilution series from a solution to be diluted, which contains a substance to be diluted, and a dilution solution, includes a body of rotation, a drive configured to subject the body of rotation to rotations having different rotation protocols, and a controller configured to control the drive so as to subject the body of rotation to the different rotational frequencies. A first mixing chamber and a second mixing chamber are connected via a fluidic connection which enables producing, in the first mixing chamber, a first mixture having a first dilution ratio, transferring a partial volume of the first mixture into the second mixing chamber, and there producing a second mixture having a second dilution ratio.
    Type: Application
    Filed: May 11, 2012
    Publication date: December 13, 2012
    Applicant: Albert-Ludwigs-Universitaet Freiburg
    Inventors: Guenter ROTH, Oliver STROHMEIER, Roland ZENGERLE
  • Publication number: 20120015844
    Abstract: A method of producing a replicate or derivative of an array of molecules, the array having a spatial arrangement of separate samples of molecules, includes creating, for each sample, at least one spatially limited effective area which is separate from the effective areas of the other samples, a surface, provided with a binding adapter or binding properties, of a carrier bordering on the effective areas. The molecules are amplified by means of amplifying agents in the effective areas for creating replicates or derivatives of the samples. The replicates or derivatives of the samples are bound to the carrier by means of the binding adapter or the binding properties, so that a spatial arrangement of the replicates or derivatives of the samples on the carrier corresponds to the spatial arrangement of the samples in the array. The carrier having the copies of the samples is removed from the array.
    Type: Application
    Filed: September 2, 2011
    Publication date: January 19, 2012
    Applicants: Albert-Ludwigs-Universitaet Freiburg, Hahn-Schickard-Gesellschaft fuer angewandte Forschung e.V.
    Inventors: Roland ZENGERLE, Felix VON STETTEN, Guenter ROTH, Jochen HOFFMANN
  • Publication number: 20110115501
    Abstract: A measuring device has a micro-electromechanical capacitive sensor which has electrodes which move toward and away from each other for measurement of a mechanical deflection of a test mass. The measuring device has a charge integrator which has an operating amplifier which has at least one amplifier input connected to the sensor and an amplifier output which is fed back to the amplifier input via an integration capacitor. The amplifier input is connected via a high-resistance electrical resistor to a terminal for an electrical common-mode reference potential. In addition to the amplifier input, the operating amplifier has an auxiliary input. The amplifier output is connected to the auxiliary input via a deep pass.
    Type: Application
    Filed: July 6, 2009
    Publication date: May 19, 2011
    Applicant: ALBERT-LUDWIGS-UNIVERSITÄT FREIBURG
    Inventors: Lin He, Yiannos Manoli, Alexander Buhmann, Armin Taschwer, Thomas Northemann
  • Patent number: 7943386
    Abstract: An apparatus for determining the volume fractions of the phases in a suspension includes a body, a channel structure, which is formed in the body, and an inlet area and a blind channel, which is fluidically connected to and capable of being filled via the same. Furthermore, a drive for imparting the body with rotation, so that phase separation of the suspension in the blind channel takes place, is provided. The blind channel includes such a channel cross-section and/or such wetting properties that, when filling same via the inlet area, higher capillary forces act in a first cross-sectional area than in a second cross-sectional area, so that at first the first cross-sectional area fills in the direction from the inlet area toward the blind end of the blind channel and then the second cross-sectional area fills in the direction from the blind end toward the inlet area.
    Type: Grant
    Filed: October 5, 2006
    Date of Patent: May 17, 2011
    Assignee: Albert-Ludwigs-Universitaet Freiburg
    Inventors: Markus Grumann, Jens Ducrée, Roland Zengerle, Lutz Riegger
  • Publication number: 20100307584
    Abstract: A solar element with increased efficiency and also a method for increasing the efficiency of a solar cell are provided. The solar cell comprises a luminescent element, an upconverter, and also at least one selectively reflecting structure.
    Type: Application
    Filed: July 15, 2008
    Publication date: December 9, 2010
    Applicants: FRAUNHOFER-GESELLSCHAFT ZUR FOERDERUNG DER ANGEWANDTEN FORSCHUNG E.V., ALBERT-LUDWIGS-UNIVERSITAET FREIBURG
    Inventors: Jan Christoph Goldschmidt, Philipp Loeper, Marius Peters
  • Publication number: 20100274746
    Abstract: Method and device for computer-aided prediction of intended movements from neuronal signals of a brain, wherein the neuronal signals are each associated in the brain with intended movements, wherein neuronal signals are recorded and the most probable movements are determined from these, specifically using a predetermined model in which a recorded neuronal signal and a determined movement are assigned to each other, and, for the probability with which a recorded neuronal signal corresponds to a respective predetermined movement, a predetermined distribution is assumed that is defined by specific characteristic values, wherein an adaptation of the neuronal signal is included in the predetermined model.
    Type: Application
    Filed: June 23, 2008
    Publication date: October 28, 2010
    Applicant: ALBERT-LUDWIGS-UNIVERSITÄT FREIBURG
    Inventors: Jörn Rickert, Carsten Mehring, Julie Blumberg, Daniel Braun, Tomislav Milekovic, Jörg Fischer
  • Publication number: 20100267194
    Abstract: An electrical contact is applied on a semiconducting substrate, such as a solar cell. A layer of metallic powder is applied on the substrate. A laser beam is the guided over the substrate for local sintering and/or melting of the metallic powder. The non-sintered or non-melted metallic powder is then removed from the substrate.
    Type: Application
    Filed: June 26, 2007
    Publication date: October 21, 2010
    Applicants: Fraunhofer-Gesellschaft zur Förderung der angewandten Forschung e.V., Albert-Ludwig-Universität Freiburg
    Inventors: Mónica Alemán, Ansgar Mette, Stefan Glunz, Ralf Preu
  • Publication number: 20100221812
    Abstract: The present invention relates to the recombinant modification of microorganisms, in particular actinomycetes. This is effected with the use of the recombination systems Dre-rox and Cre-lox. The present invention provides novel nucleotide sequences for the recombinases of the abovementioned recombination systems. Here, synthetic genes which have the codons preferred by actinomycetes and can therefore be used in these host organisms were produced. With the method according to the invention for modifying microorganisms, it is possible to produce overproduction strains which are of economic importance for the production of medical active substances.
    Type: Application
    Filed: February 12, 2008
    Publication date: September 2, 2010
    Applicant: ALBERT-LUDWIGS-UNIVERSITÄT FREIBURG
    Inventors: Andreas Bechthold, Andriy Luzhetskyy, Lutz Petzke, Elisabeth Welle, Marta Fedoryshyn, Martina Daum, Simone Herrmann
  • Publication number: 20100190224
    Abstract: The present invention relates to an isolated DNA, which is selected from the following sequences: a) a sequence according to SEQ ID No. 01, b) an intron-free sequence that is derived from a sequence according to a) and encodes the same protein or peptide as the sequence according to SEQ ID No. 01, c) a sequence that encodes a protein or peptide, which comprises the amino acid sequence according to SEQ ID No. 02, d) a sequence that is at least 80% identical to a sequence according to a) to c), e) a sequence that hybridizes with the antisense strand of a sequence according to one of the groups a) to d) or would hybridize taking into account degeneration of the genetic code, f) a derivative of a sequence according to one of the groups a) to e) obtained by substitution, addition, inversion and/or deletion of one or more bases, g) a sequence that corresponds to SEQ ID No. 01 within the degeneration of the genetic code, h) a sequence with neutral sense mutations of SEQ ID No.
    Type: Application
    Filed: March 27, 2008
    Publication date: July 29, 2010
    Applicants: EVONIK DEGUSSA Gmbh, ALBERT-LUDWIG-UNIVERSITAET FREIBURG
    Inventors: Markus Poetter, Achim Marx, Georg Fuchs, Birgit Alber, Tobias Juergen Erb
  • Patent number: 7748962
    Abstract: A fluid handling apparatus includes a body, which comprises a fluid handling structure, and a flexible membrane attached to the body and formed to interact with a fluid in the fluid handling structure, wherein the membrane comprises a first actuation component. A second actuation component is provided, wherein the first and the second actuation component are formed such that the same attract or repel each other in a first positional relationship, in order to actuate the flexible membrane. A driving means is provided to move the body relative to the second actuation component, in order to bring the first and the second actuation component into the first and out of the first positional relationship.
    Type: Grant
    Filed: January 18, 2007
    Date of Patent: July 6, 2010
    Assignee: Albert-Ludwigs-Universitaet Freiburg
    Inventors: Stefan Haeberle, Jens Ducrée, Roland Zengerle, Norbert Schmitt
  • Publication number: 20100160940
    Abstract: A surgical instrument has a shaft, an end effector comprising at least one movably mounted tool element and defining a longitudinal axis, and a force transmitting member mounted in the shaft for movement in the distal and proximal directions for transmitting an actuating force introduced at a proximal end of the instrument onto the end effector in order to move the at least one tool element from a first tool element position to a second tool element position and/or vice versa. The at least one tool element is pivotably mounted on a bearing shaft held on the shaft. The at least one tool element is connected by at least one articulation member, at least a section of which is flexible, to the force transmitting member in order to transmit the actuating force from the force transmitting member onto the at least one tool element.
    Type: Application
    Filed: December 17, 2009
    Publication date: June 24, 2010
    Applicants: Aesculap AG, Albert-Ludwigs-Universitaet Freiburg
    Inventors: Theodor Lutze, Dirk Schauer, Alexander Disch, Holger Reinecke, Claas Mueller
  • Publication number: 20100144079
    Abstract: The invention relates to a method for the precision processing of substrates, in particular for the microstructuring of thin layers, local dopant introduction and also local application of a metal nucleation layer in which a liquid-assisted laser, i.e. laser irradiation of a substrate which is covered in the regions to be processed by a suitable reactive liquid, is implemented.
    Type: Application
    Filed: March 6, 2008
    Publication date: June 10, 2010
    Applicants: Fraunhofer-Gesellschaft zur Förderung der Angewandten Forschung e.V., ALBERT-LUDWIGS-UNIVERSITÄT FREIBURG
    Inventors: Kuno Mayer, Monica Aleman, Daniel Kray, Stefan Glunz, Ansgar Mette, Ralf Preu, Andreas Grohe
  • Publication number: 20100005885
    Abstract: In a method for determining the relative position, velocity, acceleration, and/or the rotation center of a body displaceable in a three dimensional space, at least twelve linear acceleration sensors are provided and in each case arranged on a position which is stationarily fixed with respect to the body. At least one acceleration measurement signal is captured by the linear acceleration sensors. A position, velocity, acceleration, and/or rotation center signal is generated for the body from the acceleration measurement signal and data describing the position and orientation of the linear acceleration sensors in the body-fixed coordinate system.
    Type: Application
    Filed: May 19, 2006
    Publication date: January 14, 2010
    Applicant: ALBERT-LUDWIGS-UNIVERSITÄT FREIBURG
    Inventors: Christian Peters, Alexander Buhmann, Yiannos Manoli
  • Publication number: 20080292671
    Abstract: The invention relates to a medicotechnical product having an antimicrobial finish of a complex material of metal nanoparticles and macromolecules, the macromolecules being formed at least partially from a polyamino acid.
    Type: Application
    Filed: September 7, 2006
    Publication date: November 27, 2008
    Applicants: AESCULAP AG & CO. KG, ALBERT-LUDWIG-UNIVERSITÄT FREIBURG
    Inventors: Chau Hon Ho, Erich K. Odermatt, Rainer Bargon, Jorg Tiller
  • Publication number: 20080128014
    Abstract: The present invention relates to an arrangement having at least one solar cell, which is formed by a first sequence of differently doped layers (1, 2, 11, 12) on a substrate (6, 16), and at least one bypass diode, which is connected to the solar cell, particularly in a monolithic, series-connected solar module. The arrangement is characterised in that the bypass diode is formed by a second sequence of layers (4, 5, 13, 14), which is arranged between the substrate (6, 16) and the first layer sequence (1, 2, 11, 12). With the proposed arrangement monolithic, series-connected solar modules can be formed at a very low loss of active receiving surface, the solar cells of which are protected by bypass diodes.
    Type: Application
    Filed: November 3, 2005
    Publication date: June 5, 2008
    Applicants: Fraunhofer-Gesellschaft zur Förderung der Angewandten Forschung e.V., RWE Space Solar Power GmbH, Albert-Ludwigs-Universität Freiburg
    Inventors: Sascha Van Riesen, Rudiger Lockenhoff, Gerhard Strobl, Ron Dietrich, Wolfgang Koestler
  • Patent number: 7371330
    Abstract: A particle sedimentation apparatus includes a rotation body rotatable about a rotation axis and a separation chamber formed in the rotation body, to cause sedimentation of particle suspension in the separation chamber upon rotation of the rotation body. The particles accumulate in a radially outward region of the separation chamber. A flow-rate-determining inflow channel having azimuthal path length with an inflow channel inlet and an inflow channel outlet is formed in the rotation body, the inflow channel inlet being arranged radially further inwardly than the inflow channel outlet, the inflow channel outlet being fluidically connected to the separation chamber and formed to introduce particle suspension into the separation chamber upon rotation of the rotation body. Furthermore, an outflow channel is formed in the rotation body with an outflow channel inlet and an outflow channel outlet, to at least partially drain supernatant liquid formed by sedimentation from the separation chamber.
    Type: Grant
    Filed: March 23, 2007
    Date of Patent: May 13, 2008
    Assignee: Albert-Ludwigs-Universitaet Freiburg
    Inventors: Jens Ducree, Roland Zengerle, Stefan Haeberle, Thilo Brenner
  • Publication number: 20070189910
    Abstract: A fluid handling apparatus includes a body, which comprises a fluid handling structure, and a flexible membrane attached to the body and formed to interact with a fluid in the fluid handling structure, wherein the membrane comprises a first actuation component. A second actuation component is provided, wherein the first and the second actuation component are formed such that the same attract or repel each other in a first positional relationship, in order to actuate the flexible membrane. A driving means is provided to move the body relative to the second actuation component, in order to bring the first and the second actuation component into the first and out of the first positional relationship.
    Type: Application
    Filed: January 18, 2007
    Publication date: August 16, 2007
    Applicant: ALBERT-LUDWIGS-UNIVERSITAET FREIBURG
    Inventors: Stefan Haeberle, Jens Ducree, Roland Zengerle, Norbert Schmitt
  • Patent number: 6320381
    Abstract: A method of spatially resolved magnetic resonance spectroscopy according to the principle of chemical shift imaging (=CSI) in which, through application of an excitation pulse, spins in a measuring volume are excited and a metabolite signal thereof is read out, wherein between the excitation pulse and the recording of the signal, spatial encoding of the signal is effected by means of a gradient pulse in at least one spatial direction, wherein said spatial encoding gradient is varied between each recording step, such that one obtains spatial allocation of the recorded signals in the partial volume of the measuring volume, is characterized in that a reference signal is recorded in addition to the signal of the recorded metabolites, which comprises the same spatial encoding as the metabolite signal, wherein the recording of the two signals is effected in a convoluted manner.
    Type: Grant
    Filed: December 17, 1999
    Date of Patent: November 20, 2001
    Assignee: Klinikum der Albert-Ludwigs-Universität Freiburg
    Inventor: Juergen Hennig