Patents Assigned to Alcon
  • Angiostatic steroids
    Patent number: 6011023
    Abstract: Methods and compositions for preventing and treating neovascularization with steroids is disclosed.
    Type: Grant
    Filed: August 27, 1997
    Date of Patent: January 4, 2000
    Assignee: Alcon Laboratories, Inc.
    Inventors: Abbot F. Clark, Raymond E. Conrow
  • Surgical handpiece
    Patent number: 6004284
    Abstract: A surgical handpiece driver having a pumping chamber. The pumping chamber works by boiling a small volume of a fluid. As the fluid boils, it expands rapidly, thereby propelling a piston down the length of the pumping chamber. The piston may be attached to the operative shaft or rod of a surgical probe and produce reciprocal motion. Alternatively, the piston may be attached to a cam or gear to product rotary motion.
    Type: Grant
    Filed: March 11, 1999
    Date of Patent: December 21, 1999
    Assignee: Alcon Laboratories, Inc.
    Inventors: Glenn Sussman, Thomas G. Capetan
  • Materials for use in glaucoma filtration devices
    Patent number: 6001128
    Abstract: Improved glaucoma filtration device materials comprise at least one monomer having the formula: ##STR1## wherein: X is H or CH.sub.3 ;m is 0-10;Y is nothing, O, or S;R is nothing, H, or an aliphatic, aromatic or aliphatic/aromatic combination of up to twelve carbon atoms, which can be unsubstituted or substituted with Cl, F, Br, or an alkoxy of up to four carbon atoms; anda cross-linking monomer having two or more ethylenically unsaturated groups.
    Type: Grant
    Filed: May 29, 1998
    Date of Patent: December 14, 1999
    Assignee: Alcon Laboratories, Inc.
    Inventors: Gustav Graff, Mutlu Karakelle, John W. Sheets, Jr., John M. Yanni
  • Tip for a liquefaction handpiece
    Patent number: 5997499
    Abstract: A tip for a liquefraction surgical handpiece. The tip uses at least two lumens. One lumen is used for aspiration and another, smaller lumen is used to inject heated surgical fluid for liquefying a cataractous lens. The distal portion of the injection lumen terminates just inside of the aspiration lumen so that heated fluid escaping the injection lumen is reflected off of the internal wall of the aspiration lumen prior to entering the eye. Such an arrangement prevents the injected fluid from directly entering the eye. The handpiece may also contain other lumen, for example, for injecting relatively cool surgical fluid.
    Type: Grant
    Filed: August 6, 1998
    Date of Patent: December 7, 1999
    Assignee: Alcon Laboratories, Inc.
    Inventors: Glenn Sussman, Donald M. Cohen
  • Esters of non-steroidal anti-flammatory carboxylic acids
    Patent number: 5998465
    Abstract: Compounds having anti-inflammatory and anti-oxidant activity are disclosed. The compounds are useful in preventing and treating inflammatory disorders through several mechanisms. Methods of treatment employing these properties of the compounds and corresponding pharmaceutical compositions are disclosed.
    Type: Grant
    Filed: August 25, 1998
    Date of Patent: December 7, 1999
    Assignee: Alcon Laboratories, Inc.
    Inventors: Mark Hellberg, Pete Delgado, Jon C. Nixon
  • Substituted tetrahydrofuran analogs of prostaglandins as ocular hypotensives
    Patent number: 5994397
    Abstract: Substituted tetrahydrofuran analogs of prostagladins and methods of their use in treating glaucoma and ocular hypertension are disclosed.
    Type: Grant
    Filed: April 4, 1997
    Date of Patent: November 30, 1999
    Assignee: Alcon Laboratories, Inc.
    Inventors: Robert D. Selliah, Peter G. Klimko
  • Angiostatic agents and methods and compositions for controlling ocular hypertension
    Patent number: 5990099
    Abstract: Compositions of angiostatic agents for treating GLC1A glaucoma and methods for their use are disclosed.
    Type: Grant
    Filed: December 19, 1997
    Date of Patent: November 23, 1999
    Assignee: Alcon Laboratories, Inc.
    Inventor: Abbot F. Clark
  • Pumping chamber for a liquefaction handpiece having a countersink electrode
    Patent number: 5989212
    Abstract: A surgical handpiece having at least two lumens mounted to a body. At least one lumen is used for aspiration and at least one other lumen is used to inject heated surgical fluid for liquefying a cataractous lens. A portion of the second lumen is enlarged to form a pumping chamber. The pumping chamber works by boiling a small volume of the surgical fluid. As the fluid boils, it expands rapidly, thereby propelling the liquid downstream of the pumping chamber out of the second lumen. The pumping chamber may use a pair of electrodes, at least one of the electrodes containing a countersink.
    Type: Grant
    Filed: August 6, 1998
    Date of Patent: November 23, 1999
    Assignee: Alcon Laboratories, Inc.
    Inventors: Glenn Sussman, Donald M. Cohen
  • Sustained release ophthalmic antibiotic compositions
    Patent number: 5985259
    Abstract: An improved method of sterilizing the field of surgery prior to an ophthalmic surgical procedure is described. The invention eliminates the need for painfull and potentially traumatic injections of antibiotics by utilizing sustained release compositions which allow the antibiotics contained therein to penetrate deeply into the eye, thereby ensuring a sterile field of surgery during intraocular surgical procedures. The compositions may also be utilized to prevent post-surgical infections.
    Type: Grant
    Filed: April 30, 1997
    Date of Patent: November 16, 1999
    Assignee: Alcon Laboratories, Inc.
    Inventors: Gerald D. Cagle, Tai-Lee Ke, Barry A. Schlech, Ole J. Lorenzetti
  • Preservative systems for pharmaceutical compositions containing cyclodextrins
    Patent number: 5985310
    Abstract: Disclosed are preservative systems useful in aqueous pharmaceutical compositions containing an active agent and a cyclodextrin. The preservative systems comprise boric acid and one or more compounds selected from the group consisting of C.sub.16 benzalkonium halide compounds, polymeric quatemary ammonium compounds, and quatemary ammonium alkylene glycol phospholipid derivatives of the following structure ##STR1## where a+b=3; R.sup.1 is C.sub.8 -C.sub.22 alkyl or alkene; X is NH, O, or CH.sub.2 ; R.sup.2 is C.sub.2 -C.sub.6 alkyl; each R.sup.3 is independently C.sub.1 -C.sub.12 alkyl or alkene; and Y is nothing or C.sub.1 -C.sub.6 alkyl or alkene; and pharmaceutically acceptable salts thereof.
    Type: Grant
    Filed: March 10, 1998
    Date of Patent: November 16, 1999
    Assignee: Alcon Laboratories, Inc.
    Inventors: Ernesto J. Castillo, Ramon L. Espino
  • Intraocular lens injection system
    Patent number: 5976150
    Abstract: A hinged, relatively rigid substrate on which a foldable IOL is held by a thin, relatively non-elastic film of esterified hyaluronate. When the substrate is folded along the hinge, the film covering the IOL causes the IOL to also fold along the hinge. The folded lens can then be placed in a conventional IOL injector handpiece that has been modified to include a cutter or the like to separate the film-encased IOL from the substrate prior to injection into the eye.
    Type: Grant
    Filed: August 25, 1998
    Date of Patent: November 2, 1999
    Assignee: Alcon Laboratories, Inc.
    Inventor: Barry L. Copeland
  • Steroids which inhibit angiogenesis
    Patent number: 5972922
    Abstract: Novel angiostatic .DELTA..sup.4,9(11) -steroids (I), ##STR1## C.sub.21 -oxygenated steroids (II) and other known steroidal compounds have been found to be useful in treating angiogenesis in mammals who have a need for the same. These steroids are useful in treating diseases of neovascularization such as cancer, diabetes and arthritis.
    Type: Grant
    Filed: December 21, 1995
    Date of Patent: October 26, 1999
    Assignee: Alcon Laboratories, Inc.
    Inventors: John W. Wilks, Thomas F. DeKoning, Paul A. Aristoff
  • Intraocular data display device
    Patent number: 5969791
    Abstract: An intraocular data display device having an N.times.M display with each row (N) and column (M) of the display confined by a planar waveguide array. The waveguides will form uniform pixel size anywhere on the display and ensure uniform pixel luminance across the display.
    Type: Grant
    Filed: September 23, 1998
    Date of Patent: October 19, 1999
    Assignee: Alcon Laboratories, Inc.
    Inventor: T. Scott Rowe
  • Use of .omega.-conotoxin analogs for treating retinal and optic nerve head damage
    Patent number: 5965534
    Abstract: The invention is directed to the use of .omega.-conotoxins for the prevention and treatment of retinal or optic nerve head damage in humans. Compositions and methods are disclosed.
    Type: Grant
    Filed: March 13, 1998
    Date of Patent: October 12, 1999
    Assignee: Alcon Laboratories, Inc.
    Inventors: Iok-Hou Pang, Michael Kapin, Mark Hellberg
  • Apparatus for tuning and controlling an ultrasonic handpiece having both a programmable broad spectrum source and a single frequency source
    Patent number: 5959390
    Abstract: A system and method for tuning and controlling ultrasonic handpieces by incorporating a broad-spectrum signal as at least a component of the signal used to drive the handpiece. The response of the handpiece to this broad-spectrum signal is measured and the frequency or amplitude or both of the drive signal are adjusted in order to maintain the desired level of handpiece performance. The operation of the systems and the performance of the methods described enables the handpiece to be operated in a most effective manner over a more widely varying range of mechanical load and thermal conditions than was possible through the use of prior control systems and methods.
    Type: Grant
    Filed: October 1, 1998
    Date of Patent: September 28, 1999
    Assignee: Alcon Laboratories, Inc.
    Inventor: Mikhail Boukhny
  • Use of platelet derived growth factor to enhance wound healing
    Patent number: 5955436
    Abstract: Disclosed is the use of platelet derived growth factor for the enhancement of wound healing wherein the growth factor is either singularly or multiply dosed on a single day, rather than multiply dosed over a number of days. Also disclosed are pharmaceutical compositions comprising platelet derived growth factor.
    Type: Grant
    Filed: December 19, 1994
    Date of Patent: September 21, 1999
    Assignee: Alcon Laboratories, Inc.
    Inventor: H. Melvin Kunkle, Jr.
  • Treatment of retinal edema with brinzolamide
    Patent number: 5948801
    Abstract: Methods for preventing and treating retinal edema with brinzolamide are disclosed.
    Type: Grant
    Filed: March 9, 1998
    Date of Patent: September 7, 1999
    Assignee: Alcon Laboratories, Inc.
    Inventors: Rupa Doshi, Michael A. Kapin
  • Asymmetric intraocular lens injection cartridge
    Patent number: 5947976
    Abstract: A lens injector cartridge having an asymmetric bore. The asymmetric bore initiates the folding of the lens on one side only, thereby reducing the amount of energy imparted to the lens and the potential for damage to the lens. The gentle folding of the lens also assists in positioning the travel of the haptics down the bore, thereby reducing the potential for damage to the haptics.
    Type: Grant
    Filed: June 2, 1998
    Date of Patent: September 7, 1999
    Assignee: Alcon Laboratories, Inc.
    Inventors: Stephen J. Van Noy, Kyle Brown, David A. Downer, David Eister, Lars D. Jensen
  • Stable liquid enzyme compositions and methods of use in contact lens cleaning and disinfecting systems
    Patent number: 5948738
    Abstract: Stable liquid enzyme compositions containing an ophthalmically acceptable enzyme and methods involving the combined use of these compositions with a polymeric antimicrobial agent are disclosed for the simultaneous cleaning and disinfecting of contact lens. Methods for a daily use regimen are also disclosed.
    Type: Grant
    Filed: October 6, 1998
    Date of Patent: September 7, 1999
    Assignee: Alcon Laboratories, Inc.
    Inventors: Masood A. Chowhan, Ronald P. Quintana, Bahram Asgharian, Bor-Shyue Hong, Thierry Bilbault, Ruth A. Rosenthal
  • Stable liquid enzyme compositions and methods of use in contact lens cleaning and disinfecting systems
    Patent number: 5939369
    Abstract: Stable liquid enzyme compositions containing an ophthalmically acceptable enzyme and methods involving the combined use of these compositions with a polymeric antimicrobial agent are disclosed for the simultaneous cleaning and disinfecting of contact lens. Methods for a daily use regimen are also disclosed.
    Type: Grant
    Filed: August 2, 1996
    Date of Patent: August 17, 1999
    Assignee: Alcon Laboratories, Inc.
    Inventors: Masood A. Chowhan, Ronald P. Quintana, Bahram Asgharian, Bor-Shyue Hong, Thierry Bilbault, Ruth A. Rosenthal