Patents Assigned to Alcon
  • Method of treating angiogenesis-related disorders
    Publication number: 20020037929
    Abstract: The use of 3-benzolphenylacetic acids and derivatives, including nepafenac, to treat angiogenesis-related disorders, including ophthalmic angiogenesis-related disorders such as diabetic retinopathy and exudative macular degeneration, is disclosed.
    Type: Application
    Filed: August 13, 2001
    Publication date: March 28, 2002
    Applicant: Alcon Universal Ltd.
    Inventors: Michael A. Kapin, David P. Bingaman, Daniel A. Gamache, Gustav Graff, John M. Yanni
  • Process for manufacturing compositions containinig ciprofloxacin and hydrocortisone
    Publication number: 20020037883
    Abstract: This invention is directed toward a method of preparing a topical composition comprising ciprofloxacin and hydrocortisone. The method involves dispersing hydrocortisone with lecithin for greater than 45 minutes prior to combining hydrocortisone with the balance of the composition.
    Type: Application
    Filed: July 16, 2001
    Publication date: March 28, 2002
    Applicant: Alcon Universal Ltd.
    Inventor: Onkar N. Singh
  • Pharmaceutical suspension compositions lacking a polymeric suspending agent
    Publication number: 20020037877
    Abstract: Stable aqueous pharmaceutical suspension compositions containing lecithin as a stabilizing additive and lacking a polymeric suspending agent are disclosed.
    Type: Application
    Filed: July 16, 2001
    Publication date: March 28, 2002
    Applicant: Alcon Universal Ltd.
    Inventor: Onkar N. Singh
  • Pharmaceutical compositions containing tobramycin and xanthan gum
    Publication number: 20020035088
    Abstract: Topically administrable aqueous solution compositions containing tobramycin and xanthan gum are disclosed. The solution compositions contain a buffering agent and a pH-adjusting agent in an amount sufficient to achieve a pH above 7.8 in order to minimize or avoid compatibility problems between tobramycin and xanthan gum.
    Type: Application
    Filed: July 11, 2001
    Publication date: March 21, 2002
    Applicant: Alcon Universal Ltd.
    Inventors: Nuria Carreras Perdiguer, Jose Alberto Vallet Mas, Gemma Torrella Cabello
  • Lamellar dissecting instrument
    Patent number: 6358261
    Abstract: A microsurgical instrument that includes a handle and a dissecting tip coupled to the handle is disclosed. The tip includes a blade having a generally elliptical three-dimensional geometry. The blade may include an edge having a first arc and an opposing second arc. When the instrument is used to form an intracorneal pocket for the implantation of an intracorneal optical lens, the curvature of the first arc allows the edge to dissect a first blind spot of the pocket, and the curvature of the second arc allows the edge to dissect a second blind spot of the pocket. The blade may also be formed with a first depression in its top surface and a second depression in its bottom surface. When the instrument is used to form an intracorneal pocket, the depressions reduce the drag on, and corresponding trauma to, stromal tissue.
    Type: Grant
    Filed: November 5, 1999
    Date of Patent: March 19, 2002
    Assignee: Alcon Universal Ltd.
    Inventors: Kwan Y. Chan, Gregory S. Milios, David E. Booth, Dyson W. Hickingbotham
  • Alkyl trypsin compositions and methods of use in contact lens cleaning and disinfecting systems
    Patent number: 6358897
    Abstract: Improved stability, liquid enzyme compositions containing an alkylated trypsin and methods involving the combined use of these compositions with an aqueous composition are disclosed for the cleaning or simultaneous cleaning and disinfecting of contact lens. Methods for a daily use regimen are also disclosed.
    Type: Grant
    Filed: September 1, 1998
    Date of Patent: March 19, 2002
    Assignee: Alcon Laboratories, Inc.
    Inventors: Bor-Shyue Hong, Bahram Asgharian, Ronald P. Quintana
  • Topical suspension formulations containing ciprofloxacin and dexamethasone
    Patent number: 6359016
    Abstract: Suspension formulations containing dexamethasone and ciprofloxacin are disclosed. The formulations contain a nonionic polymer, a nonionic surfactant and an ionic tonicity agent, but are physically stable and easily re-suspended. The formulations are intended for topical application to the eye, ear or nose.
    Type: Grant
    Filed: May 25, 2001
    Date of Patent: March 19, 2002
    Assignee: Alcon Universal Ltd.
    Inventors: Onkar N. Singh, Haresh G. Bhagat
  • Lamellar dissecting instrument
    Patent number: 6358262
    Abstract: A microsurgical instrument having a handle and a dissecting tip coupled to the handle is disclosed. The handle includes a cannula for transporting surgical fluid. The dissecting tip includes a blade for dissecting tissue and an aperture for delivering the fluid. The instrument may be used to more effectively create an intracorneal pocket for the implantation of an intracorneal optical lens.
    Type: Grant
    Filed: December 20, 1999
    Date of Patent: March 19, 2002
    Assignee: Alcon Universal Ltd.
    Inventors: Kwan Y. Chan, Gregory S. Milios, David E. Booth, Dyson W. Hickingbotham
  • Switchable tackiness coating compositions for ophthalmic implants
    Publication number: 20020028330
    Abstract: The application of switchable tackiness coating compositions to ophthalmic implants provides the benefits of body temperature tackiness without the disadvantages of room temperature tackiness.
    Type: Application
    Filed: August 24, 2001
    Publication date: March 7, 2002
    Applicant: Alcon Universal Ltd.
    Inventors: Anilbhai S. Patel, Douglas C. Schlueter, Mutlu Karakelle
  • Phospholipids of hydroxyeicosatetraenoic acid-like derivatives and methods of use
    Patent number: 6353032
    Abstract: Phospholipid-HETE derivatives, compositions and methods of use are disclosed. The compounds are particularly useful for treating dry eye.
    Type: Grant
    Filed: October 23, 2000
    Date of Patent: March 5, 2002
    Assignee: Alcon Universal Ltd.
    Inventors: Gustav Graff, Peter G. Klimko
  • 15-ketal postaglandins for the treatment of glaucoma or ocular hypertension
    Patent number: 6353014
    Abstract: A method of treating glaucoma or ocular hypertension in a patient, which comprises administering to the patient a pharmaceutically effective amount of a compound of formula I:
    Type: Grant
    Filed: June 2, 1999
    Date of Patent: March 5, 2002
    Assignee: Alcon Laboratories, Inc.
    Inventors: Verney L. Sallee, Mark R. Hellberg, Peter G. Klimko
  • Pharmaceutical compositions containing tobramycin and xanthan gum
    Patent number: 6352978
    Abstract: Topically administrable aqueous solution compositions containing tobramycin and xanthan gum are disclosed. The solution compositions contain a buffering agent and a pH-adjusting agent in an amount sufficient to achieve a pH above 7.8 in order to minimize or avoid compatibility problems between tobramycin and xanthan gum.
    Type: Grant
    Filed: July 11, 2001
    Date of Patent: March 5, 2002
    Assignee: Alcon Universal Ltd.
    Inventors: Nuria Carreras Perdiguer, Jose Alberto Vallet Mas, Gemma Torrella Cabello
  • Compositions containing hydroxyeicosatetraenoic acid derivatives and methods of use in treating dry eye disorders
    Patent number: 6353022
    Abstract: Compositions containing one or more HETE derivative(s) and an effective concentration of ethanol and methods of use for treating dry eye are disclosed.
    Type: Grant
    Filed: October 23, 2000
    Date of Patent: March 5, 2002
    Assignee: Alcon Universal Ltd.
    Inventors: L. Wayne Schneider, Daniel A. Gamache, Lori K. Weimer, Timothy L. Kessler, Zhongyou Wei, Terri Pasquine, John M. Yanni, Haresh G. Bhagat
  • 15-Hydroxyeicosatetraenoic acid-related compounds and methods of use
    Patent number: 6353012
    Abstract: HETE derivatives and methods of their use for treating dry eye are disclosed.
    Type: Grant
    Filed: October 23, 2000
    Date of Patent: March 5, 2002
    Assignee: Alcon Universal Ltd.
    Inventors: Mark R. Hellberg, John M. Yanni, Gustav Graff, Daniel A. Gamache, Peter G. Klimko
  • 11-halo prostaglandins for the treatment of glaucoma or ocular hypertension
    Patent number: 6353000
    Abstract: A method of treating glaucoma or ocular hypertension in a patient, which comprises administering to the patient a pharmaceutically effective amount of a compound of formula I:
    Type: Grant
    Filed: June 2, 1999
    Date of Patent: March 5, 2002
    Assignee: Alcon Laboratories, Inc.
    Inventors: Verney L. Sallee, Mark R. Hellberg, Peter G. Klimko, Paul W. Zinke
  • High refractive index ophthalmic device materials
    Patent number: 6353069
    Abstract: High refractive index copolymers suitable for use in ophthalmic devices are disclosed. The copolymers comprise a) two or more monomers of the structure: wherein: X is H or CH3; m is 0-10; Y is nothing, O, S, or NR wherein R is H, CH3, CnH2n+1(n=1-10), iso-OC3H7, C6H5, or CH2C6H5; Ar is any aromatic ring which can be unsubstituted or substituted with H, CH3, C2H5, n-C3H7, iso-C3H7, OCH3, C6H11, Cl, Br, C6H5, or CH2C6H5; a crosslinking monomer having a plurality of polymerizable ethylenically unsaturated groups, and b) a total of about 5 mole % or less of one or more monomers of the structure: wherein: X is H or CH3; W is —CH3 or (CH2═C(—X)—C(═O)—); and n is such that the weight average molecular weight is approximately 600-1000 if W is —CH3 and approximately 400-1000 if W is (CH2═C(—X)—C(═O)—).
    Type: Grant
    Filed: March 24, 2000
    Date of Patent: March 5, 2002
    Assignee: Alcon Manufacturing, Ltd.
    Inventors: Charles Freeman, David L. Jinkerson, Mutlu Karakelle, Albert R. Leboeuf
  • 15-hydroxyeicosatetraenoic acid analogs with enhanced metabolic stability and methods of their use in treating dry eye disorders
    Patent number: 6348496
    Abstract: 15-HETE derivatives with enhanced metabolic stability and methods of their use for treating dry eye are disclosed.
    Type: Grant
    Filed: July 11, 2001
    Date of Patent: February 19, 2002
    Assignee: Alcon Universal Ltd.
    Inventor: David B. Belanger
  • Use of cloprostenol and fluprostenol analogues to treat glaucoma and ocular hypertension
    Patent number: 6344478
    Abstract: Disclosed is the use of cloprostenol and fluprostenol analogues in combination with carbonic anhydrase inhibitors for the treatment of glaucoma and ocular hypertension and ophthalmic compositions therefor.
    Type: Grant
    Filed: February 6, 2001
    Date of Patent: February 5, 2002
    Assignee: Alcon Manufacturing, Ltd.
    Inventors: Thomas R. Dean, Jesse A. May, Verney L. Sallee, Louis Desantis, Jr.
  • Method of prostaglandin synthesis
    Patent number: 6344581
    Abstract: Methods of synthesizing 9-Halo-13,14-dihydroprostaglandins useful in the treatment of glaucoma and ocular hypertension are disclosed. Also disclosed are ophthalmic, pharmaceutical compositions comprising such prostaglandins.
    Type: Grant
    Filed: October 31, 1997
    Date of Patent: February 5, 2002
    Assignee: Alcon Manufacturing, Ltd.
    Inventors: Raymond E. Conrow, Paul W. Zinke, Peter G. Klimko, Robert D. Selliah
  • Prostaglandin e agonists for treatment of dry eye
    Patent number: 6344477
    Abstract: Compositions and methods for the treatment of dry eye and related diseases utilizing EP4 receptor agonists are disclosed.
    Type: Grant
    Filed: January 12, 2000
    Date of Patent: February 5, 2002
    Assignee: Alcon Manufacturing, Ltd.
    Inventor: Najam A. Sharif