Patents Assigned to Alcon
  • Sulfated polyvinyl alcohol polymers to stabilize pharmaceutical drug compounds
    Patent number: 5662919
    Abstract: Stable formulations of positively charged, hydrolytically unstable drug compounds are obtained by adding a sulfated polyvinyl alcohol copolymer to the formulations.
    Type: Grant
    Filed: November 21, 1994
    Date of Patent: September 2, 1997
    Assignee: Alcon Laboratories, Inc.
    Inventors: Ernesto J. Castillo, Yusuf Ali, Ruma P. Sarkar
  • Method of varying luminous intensity of light in an illumination system
    Patent number: 5658070
    Abstract: A fiberoptic illumination system having an attenuator with a "multiple wedge" aperture that more uniformly attenuates the light beam striking the fiberoptic without changing the color temperature of the light beam or affecting the exit divergence angle of the light beam. The system includes an optical housing design having orthogonal lights paths that allows two fiberoptics to be illuminated from the same bulb, two bulbs located in primary and back-up positions, respectively, mounted on a rotating carousel and a retinal protection filter that filters out wavelengths of light harmful to the retina.
    Type: Grant
    Filed: October 27, 1994
    Date of Patent: August 19, 1997
    Assignee: Alcon Laboratories, Inc.
    Inventors: T. Scott Rowe, Eric Marason, David Wilkinson
  • Preserved ophthalmic drug compositions containing polymeric quaternary ammonium compounds
    Patent number: 5653972
    Abstract: Disclosed are storage-stable preserved ophthalmic compositions containing acidic drugs in combination with polymeric quaternary ammonium compounds and boric acid.
    Type: Grant
    Filed: August 21, 1996
    Date of Patent: August 5, 1997
    Assignee: Alcon Laboratories, Inc.
    Inventors: Suketu Dipakbhai Desai, Diane S. Nelms
  • Contact lens cleaning composition containing polyalkylene oxide modified siloxanes
    Patent number: 5654262
    Abstract: Compositions and methods are provided for cleaning and wetting of contact lenses, especially rigid, gas-permeable contact lenses. The compositions comprise low molecular weight polyalkylene oxide modified siloxanes, which are particularly effective in removing lipids from the surface of contact lenses.
    Type: Grant
    Filed: March 14, 1995
    Date of Patent: August 5, 1997
    Assignee: Alcon Laboratories, Inc.
    Inventors: Nayan N. Desai, Ronald P. Quintana, Masood A. Chowhan
  • Ethacrynic acid-like compounds and use thereof to treat glaucoma
    Patent number: 5650541
    Abstract: Compounds structurally related to ethacrynic acid are described. The compounds are useful for controlling intraocular pressure. Unlike ethacrynic acid, the compounds of the present invention are capable of effectively penetrating the cornea. Methods of controlling intraocular pressure via topical application of one or more of the compounds to the eye and topical ophthalmic compositions useful in the treatment of glaucoma are also described.
    Type: Grant
    Filed: January 11, 1996
    Date of Patent: July 22, 1997
    Assignee: Alcon Laboratories, Inc.
    Inventor: Jesse A. May
  • Thiophene sulfonamides useful as carbonic anhydrase inhibitors
    Patent number: 5646142
    Abstract: New thiophene sulfonamides useful as carbonic anhydrase inhibitors are disclosed. Methods for using the compounds to control IOP are also disclosed.
    Type: Grant
    Filed: July 8, 1994
    Date of Patent: July 8, 1997
    Assignee: Alcon Laboratories, Inc.
    Inventors: Anura P. Dantanarayana, Thomas R. Dean, Jesse A. May
  • Phacoemulsification sleeve
    Patent number: 5645530
    Abstract: A phacoemulsification sleeve having a centering ring isolated within an outer shell. A bellows-like sleeve between the handpiece and the outer shell provides a fluid path for the irrigating fluid.
    Type: Grant
    Filed: August 28, 1995
    Date of Patent: July 8, 1997
    Assignee: Alcon Laboratories, Inc.
    Inventors: Mikhail Boukhny, Thomas G. Capetan
  • Cross-linked polyethylene oxide coatings to improve the biocompatibility of implantable medical devices
    Patent number: 5645882
    Abstract: Polyethylene oxide (PEO) coatings providing improved biocompatibility for implantable medical devices are disclosed. The PEO coatings comprise functionalized end-capped PEO which is attached at one end to the medical device. The PEO compounds are then exposed to a high energy source for a time sufficient to cause the PEO compounds to form a cross-linked, insoluble network. These PEO coatings am able to survive ethylene oxide sterilization procedures with minimal loss of protein or cell repulsion ability.
    Type: Grant
    Filed: November 29, 1995
    Date of Patent: July 8, 1997
    Assignee: Alcon Laboratories, Inc.
    Inventor: Gerard Llanos
  • Compounds having both potent calcium antagonist and antioxidant activity and use thereof as cytoprotective agents
    Patent number: 5646149
    Abstract: Compounds having both calcium antagonist and antioxidant activity are disclosed. The compounds are useful in preventing or alleviating damage to tissues at the cellular level. Methods of treatment which employ these properties of the compounds and corresponding pharmaceutical compositions are also disclosed.
    Type: Grant
    Filed: June 7, 1995
    Date of Patent: July 8, 1997
    Assignee: Alcon Laboratories, Inc.
    Inventors: Mark R. Hellberg, George Barnes, Robert J. Collier, Jr.
  • Systemic administration of esters and amides of antioxidants which may be used as antioxidant prodrug therapy for oxidative and inflammatory pathogenesis
    Patent number: 5643943
    Abstract: Methods for treating vascular inflammatory pathologies are disclosed. Particularly, the methods utilize pharmaceutical compositions containing certain compounds having an anti-inflammatory and anti-oxidant moiety covalently linked by an amide or ester bond. The compounds are useful in preventing and treating inflammatory disorders through several mechanisms.
    Type: Grant
    Filed: June 7, 1995
    Date of Patent: July 1, 1997
    Assignee: Alcon Laboratories, Inc.
    Inventors: Daniel A. Gamache, Mark R. Hellberg, Jon C. Nixon, Gustav Graff
  • Topical ophthalmic formulations for treating allergic eye diseases
    Patent number: 5641805
    Abstract: Topical ophthalmic formulations of the invention contain as an active ingredient 11-(3-dimethylaminopropylidene)-6,11-dihydrodibenz[b,e]oxepin-2-acetic acid or a pharmaceutically acceptable salt thereof. The formulations are useful for treating allergic eye diseases such as allergic conjunctivitis, vernal conjunctivitis, vernal keratoconjunctivitis, and giant papillary conjunctivitis.
    Type: Grant
    Filed: June 6, 1995
    Date of Patent: June 24, 1997
    Assignees: Alcon Laboratories, Inc., Kyowa Hakko Kogyo Co. Ltd.
    Inventors: Eiji Hayakawa, Masashi Nakakura, Stella M. Robertson, John Michael Yanni
  • Apparatus and method for cleaning and disinfecting contact lenses
    Patent number: 5637497
    Abstract: A lens storage container having an interior coated with an enzymatic cleaning composition useful for cleaning and disinfecting contact lenses.
    Type: Grant
    Filed: June 28, 1995
    Date of Patent: June 10, 1997
    Assignee: Alcon Laboratories, Inc.
    Inventor: Ralph P. Stone
  • Infusion sleeve
    Patent number: 5634912
    Abstract: An infusion sleeve having a two-piece body. The first piece is conical in shape and is attached to the handpiece by conventional methods. The distal end of the first piece contains a series of annular grooves. The second piece is tubular in shape and contains an annular rim or lip on the proximal end that interlocks within the annular grooves on the first piece.
    Type: Grant
    Filed: February 12, 1996
    Date of Patent: June 3, 1997
    Assignee: Alcon Laboratories, Inc.
    Inventor: Valentine P. Injev
  • Sustained release comfort formulation for glaucoma therapy
    Patent number: 5635172
    Abstract: Disclosed are nonstinging, sustained release ophthalmic formulations to control intraocular pressure in antiglaucoma therapy comprising a basic active, a cation exchange resin, and, inter alia, an acidic, mucomimetic polymer. Also disclosed are methods of treatment comprising administering such formulations topically to the eye when indicated for control and lowering of intraocular pressure.
    Type: Grant
    Filed: February 27, 1995
    Date of Patent: June 3, 1997
    Assignee: Alcon Laboratories, Inc.
    Inventors: Rajni Jani, Robert G. Harris
  • Storage-stable prostaglandin compositions
    Patent number: 5631287
    Abstract: The use of polyethoxylated castor oils in prostaglandin compositions greatly enhances the prostaglandin's chemical stability.
    Type: Grant
    Filed: December 22, 1994
    Date of Patent: May 20, 1997
    Assignee: Alcon Laboratories, Inc.
    Inventor: L. Wayne Schneider
  • Use of amidoamines in ophthalmic compositions
    Patent number: 5631005
    Abstract: The use of certain amidoamines to disinfect contact lenses and preserve ophthalmic compositions is described. Ophthalmic compositions containing these compounds as disinfecting agents or preservatives are also described. The amidoamines utilized in the present invention have potent antibacterial and antifungal activity, and are chemically compatible with inorganic ions and other materials utilized in ophthalmic compositions.
    Type: Grant
    Filed: February 24, 1995
    Date of Patent: May 20, 1997
    Assignee: Alcon Laboratories, Inc.
    Inventors: Nissanke L. Dassanayake, Ronald L. Schlitzer, Joonsup Park
  • Use of sustained release antibiotic compositions in ophthalmic surgical procedures
    Patent number: 5631004
    Abstract: An improved method of sterilizing the field of surgery prior to an ophthalmic surgical procedure is described. The invention eliminates the need for painful and potentially traumatic injections of antibiotics by utilizing sustained release compositions which allow the antibiotics contained therein to penetrate deeply into the eye, thereby ensuring a sterile field of surgery during intraocular surgical procedures. The compositions may also be utilized to prevent post-surgical infections.
    Type: Grant
    Filed: September 30, 1993
    Date of Patent: May 20, 1997
    Assignee: Alcon Laboratories, Inc.
    Inventors: Gerald D. Cagle, Tai-Lee Ke, Barry A. Schlech, Ole J. Lorenzetti
  • Surgical console
    Patent number: D380550
    Type: Grant
    Filed: November 14, 1995
    Date of Patent: July 1, 1997
    Assignee: Alcon Laboratories, Inc.
    Inventors: James R. Dennewill, Russell L. Finlay, Paul R. Hallen, John C. Huculak, John A. Ripley, Richard L. Zaleski, II, David Weston
  • Surgical handpiece holder
    Patent number: D381421
    Type: Grant
    Filed: December 14, 1995
    Date of Patent: July 22, 1997
    Assignee: Alcon Laboratories, Inc.
    Inventors: Peter D. Casica, James Y. Chon
  • Ophthalmic lens case
    Patent number: D382399
    Type: Grant
    Filed: May 30, 1996
    Date of Patent: August 19, 1997
    Assignee: Alcon Laboratories, Inc.
    Inventors: Robert Hambleton, Stephen J. Van Noy, Yi-Ren Woo