Abstract: Methods for preventing and treating corneal haze resulting from exposure of the eye to laser irradiation are disclosed. The methods include administration of compositions of wound healing modulators to the eye. Compositions for use in preventing and treating the corneal haze are also disclosed.
Type:
Grant
Filed:
March 16, 1995
Date of Patent:
December 10, 1996
Assignee:
Alcon Laboratories, Inc.
Inventors:
Stella M. Robertson, Herman M. Kunkle, Jr.
Abstract: The use of 5-methyl-isoxazole-4-carboxylic acid anilides and 2-hydroxyethylidene-cyano acetic acid anilides for treating ocular diseases with immune etiology is disclosed.
Abstract: Methods for preventing and treating corneal haze resulting from exposure of the eye to laser irradiation are disclosed. The methods include administration of compositions of wound healing modulators to the eye. Compositions for use in preventing and treating the corneal haze are also disclosed.
Type:
Grant
Filed:
March 16, 1995
Date of Patent:
December 3, 1996
Assignee:
Alcon Laboratories, Inc.
Inventors:
Stella M. Robertson, Herman M. Kunkle, Jr.
Abstract: Disclosed are solutions useful in surgery comprising a viscous or viscoelastic substance in an aqueous vehicle which is characterized as physiologically compatible; also disclosed are methods of using such solutions, implanting such viscous or viscoelastic substances, while minimizing the traumatic effect of surgery at the cellular level.
Abstract: Compositions containing an ophthalmically acceptable enzyme of high purity and integrity in a liquid medium and methods involving the use of these compositions for cleaning a contact lens, and in combination with an antimicrobial agent for the simultaneous cleaning and disinfecting of contact lens are disclosed.
Abstract: Methods for preventing and treating corneal haze resulting from exposure of the eye to laser irradiation are disclosed. The methods include administration of compositions of wound healing modulators to the eye. Compositions for use in preventing and treating the corneal haze are also disclosed.
Type:
Grant
Filed:
March 16, 1995
Date of Patent:
November 12, 1996
Assignee:
Alcon Laboratories, Inc.
Inventors:
Stella M. Robertson, Herman M. Kunkle, Jr.
Abstract: The use of certain amidoamines to disinfect contact lenses and preserve ophthalmic compositions is described, Ophthalmic compositions containing these compounds as disinfecting agents or preservatives are also described, The amidoamines utilized in the present invention have potent antibacterial and antifungal activity, and are chemically compatible with inorganic ions and other materials utilized in ophthalmic compositions.
Type:
Grant
Filed:
February 27, 1995
Date of Patent:
November 12, 1996
Assignee:
Alcon Laboratories, Inc.
Inventors:
Nissanke L. Dassanayake, Ronald L. Schlitzer, Joonsup Park
Abstract: Disclosed is the use of combinations of F and E series prostaglandins and their respective derivatives and analogues, as well as pharmaceutically acceptable salts and esters thereof in the treatment of glaucoma and ocular hypertension. Also disclosed are ophthalmic, pharmaceutical compositions comprising said combinations.
Abstract: The present invention includes a stationary outer blade and a rotating inner cutting blade. A unique blade design and geometry allows clean, smooth cuts in fibrous tissue.
Abstract: A process for preparing defined molecular weight polymers, particularly polyquaternary ammonium compounds, is disclosed. As the molecular weights of these compounds can be absolutely defined, rather than defined merely in terms of "number average molecular weight," these compounds are particularly useful as identification standards for other polymers which are made using conventional polymerization processes. The polyquaternary ammonium compounds described are further suitable for use as antimicrobial agents, particularly in ophthalmic compositions.
Type:
Grant
Filed:
December 13, 1994
Date of Patent:
August 20, 1996
Assignee:
Alcon Laboratories, Inc.
Inventors:
Edward C. Holloman, Evan P. Kyba, Joon S. Park
Abstract: Novel polymerizable yellow dyes are disclosed. Additionally, novel and known dyes are used to block or lower the intensity of blue light transmitted through ocular lenses and other windows.
Abstract: Certain anionic surfactants are used to enhance antimicrobial effectiveness in comfortable, sustained release ophthalmic compositions containing polyelectrolytes, such as carboxyvinyl polymers, polystyrene sulfonic acid polymers and cationic exchange resins, as well as at least one active ingredient.
Abstract: Compounds of the following formula are disclosed:Compounds of Formula I are the topic of this invention: ##STR1## Wherein G, J and the two atoms of the thiophene ring to which they are attached form a six-membered ring chosen from ##STR2## The compounds are useful as carbonic anhydrase inhibitors.
Type:
Grant
Filed:
January 20, 1995
Date of Patent:
July 23, 1996
Assignee:
Alcon Laboratories, Inc.
Inventors:
Jesse A. May, Hwang-Hsing Chen, Brian DuPr e, Thomas R. Dean
Abstract: PEO-containing quaternary ammonium compounds have good broad spectrum antimicrobial activity. These compounds are useful in pharmaceutical compositions as preservatives and in contact lens care compositions as preservatives and/or disinfectants.