Patents Assigned to Alcon
  • Use of diamines in ophthalmic compositions
    Patent number: 5627214
    Abstract: Certain alkenyl diamines, the use of same for disinfecting and cleaning contact lenses and preserving ophthalmic products, and associated ophthalmic compositions are described.
    Type: Grant
    Filed: February 16, 1995
    Date of Patent: May 6, 1997
    Assignee: Alcon Laboratories, Inc.
    Inventors: Rolf Schafer, Ronald L. Schlitzer, Nissanke L. Dassanayake
  • Use of certain 9-haloprostaglandins to treat glaucoma and ocular hypertension
    Patent number: 5627209
    Abstract: 9-Haloprostaglandins are useful in the treatment of glaucoma and ocular hypertension. Also disclosed are ophthalmic, pharmaceutical compositions comprising such prostaglandins.
    Type: Grant
    Filed: October 25, 1995
    Date of Patent: May 6, 1997
    Assignee: Alcon Laboratories, Inc.
    Inventors: Louis DeSantis, Jr., Verney L. Sallee
  • Pharmaceutical compositions and methods of treatment of the cornea following laser irradiation
    Patent number: 5624893
    Abstract: Methods for treating the cornea following laser irradiation are disclosed. The methods include administration of compositions of wound healing modulators and pain mediators to the eye. Compositions for use in treating the cornea are also disclosed.
    Type: Grant
    Filed: December 13, 1994
    Date of Patent: April 29, 1997
    Assignee: Alcon Laboratories, Inc.
    Inventor: John M. Yanni
  • Three section pad in caliper disc brakes
    Patent number: 5620063
    Abstract: A disc brake caliper is made to receive a series of pads extending circumferentially of the disc. Each pad is pressurised by a pair of pistons including a smaller piston located radially outwardly and a larger piston located radially inwardly. All of the pistons and cylinders are connected together for common hydraulic pressurization. The arrangement provides better distribution of the braking force, and greater equalization of pad wear. The relatively greater area of pistons as compared to the pad area also contributes towards more even braking force, whilst the smaller diameter pistons and cylinders, as compared to what would be necessary if only a single piston and cylinder were used, enables shorter cylinder length and hence a slimmer and lighter caliper without risk of pistons tilting and jamming.
    Type: Grant
    Filed: October 30, 1995
    Date of Patent: April 15, 1997
    Assignee: Alcon Components Limited
    Inventor: Philip J. Smith
  • Topical ophthalmic carbonic anhydrase inhibitor formulations
    Patent number: 5620970
    Abstract: The present invention is directed to topical ophthalmic formulations of carbonic anhydrase inhibitors and polyethoxylated derivatives of castor oil. Methods for using the formulations for treating and controlling glaucoma and ocular hypertension are also disclosed.
    Type: Grant
    Filed: June 5, 1995
    Date of Patent: April 15, 1997
    Assignee: Alcon Laboratories, Inc.
    Inventors: Wesley W. Han, Thomas R. Dean, Steven H. Gerson, Yusuf Ali, Rajni Jani
  • Thermally-gelling drug delivery vehicles containing cellulose ethers
    Patent number: 5618800
    Abstract: Drug delivery vehicles which reversibly increase in either loss modulus or storage modulus, or both, upon contact with the eye, skin, mucous membrane or body cavity are disclosed. The vehicles contain one or more nonionic substituted cellulose ethers and do not require a charged surfactant or a pH-sensitive polymer for such increase in loss modulus or storage modulus, or both, upon administration. In one embodiment, the vehicles gel upon instillation in the eye.
    Type: Grant
    Filed: August 23, 1995
    Date of Patent: April 8, 1997
    Assignee: Alcon Laboratories, Inc.
    Inventors: Bhagwati P. Kabra, John C. Lang
  • Substantially pure apraclonidine
    Patent number: 5612364
    Abstract: Compositions containing, and methods for controlling intraocular pressure with, substantially pure apraclonidine are disclosed.
    Type: Grant
    Filed: November 8, 1995
    Date of Patent: March 18, 1997
    Assignee: Alcon Laboratories, Inc.
    Inventors: Billie M. York, John M. Yanni, Mark T. DuPriest
  • Esters and amides of non-steroidal anti-inflammatory carboxylic acids which may be used as anti-oxidants, 5-lipoxygenase inhibitors and non-steroidal anti-inflammatory prodrugs
    Patent number: 5607966
    Abstract: Compounds having anti-inflammatory and anti-oxidant activity are disclosed. The compounds are useful in preventing and treating inflammatory disorders through several mechanisms. Methods of treatment employing these properties of the compounds and corresponding pharmaceutical compositions are disclosed.
    Type: Grant
    Filed: December 23, 1994
    Date of Patent: March 4, 1997
    Assignee: Alcon Laboratories, Inc.
    Inventors: Mark R. Hellberg, Gustav Graff
  • Methods of using liquid enzyme compositions containing mixed polyols
    Patent number: 5605661
    Abstract: Compositions containing a stable, liquid, ophthalmically acceptable enzyme and methods involving the combined use of these compositions with a polymeric antimicrobial agent are disclosed for the simultaneous cleaning and disinfecting of contact lens. Methods for a daily use regimen are also disclosed.
    Type: Grant
    Filed: August 18, 1995
    Date of Patent: February 25, 1997
    Assignee: Alcon Laboratories, Inc.
    Inventors: Bahram Asgharian, Bor-Shyue Hong
  • Combinations of prostaglandins and clonidine derivatives for the treatment of glaucoma
    Patent number: 5605922
    Abstract: Combinations of at least one clonidine derivative and at least one prostaglandin are used to treat glaucoma and ocular hypertension without some of the side effects typically associated with topical administration of prostaglandins.
    Type: Grant
    Filed: December 12, 1995
    Date of Patent: February 25, 1997
    Assignee: Alcon Laboratories, Inc.
    Inventors: Louis DeSantis, Jr., Verney L. Sallee
  • Method for reducing tackiness of soft acrylic polymers
    Patent number: 5603774
    Abstract: The tackiness associated with certain soft acrylic polymers can be reduced by plasma treatment of the polymer surface. This is particularly useful with regard to intraocular lenses (IOLs), especially foldable IOLs, which are made from such soft acrylic polymers.
    Type: Grant
    Filed: December 11, 1995
    Date of Patent: February 18, 1997
    Assignee: Alcon Laboratories, Inc.
    Inventors: Albert R. LeBoeuf, George Green, Barbara A. Piper
  • Stable liquid enzyme compositions and methods of use in contact lens cleaning and disinfecting systems
    Patent number: 5604190
    Abstract: Compositions containing a stable, liquid, ophthalmically acceptable enzyme and methods involving the combined use of these compositions with a polymeric antimicrobial agent, and complexing agent are disclosed for the simultaneous cleaning and disinfecting of contact lens. Methods for a daily use regimen are also disclosed.
    Type: Grant
    Filed: June 7, 1995
    Date of Patent: February 18, 1997
    Assignee: Alcon Laboratories, Inc.
    Inventors: Masood A. Chowhan, Ronald P. Quintana, Bahram Asgharian, Bor-Shyue Hong, Thierry Bilbault, Ruth A. Rosenthal
  • Preserved ophthalmic drug compositions containing polymeric quaternary ammonium compounds
    Patent number: 5603929
    Abstract: Disclosed are storage-stable preserved ophthalmic compositions containing acidic drugs in combination with polymeric quaternary ammonium compounds and boric acid.
    Type: Grant
    Filed: November 16, 1994
    Date of Patent: February 18, 1997
    Assignee: Alcon Laboratories, Inc.
    Inventors: Suketu D. Desai, Diane S. Nelms
  • Intraocular irrigating solution containing a polyamine antagonist
    Patent number: 5604244
    Abstract: Pharmaceutical compositions useful in ophthalmic surgery are described. The compositions include one or more polyamine antagonists, and are useful for preventing or treating excitotoxicity associated with ophthalmic surgery. Methods of using the compositions in connection with ophthalmic surgical procedures are also described.
    Type: Grant
    Filed: June 7, 1995
    Date of Patent: February 18, 1997
    Assignee: Alcon Laboratories, Inc.
    Inventors: Louis DeSantis, Jr., Michael A. Kapin
  • Double redox system for disinfecting contact lenses
    Patent number: 5591397
    Abstract: An improved method for rapid disinfection of contact lenses in a convenient and reliable manner is disclosed in which a series of oxidation-reduction reactions are employed. Specifically, dichloroisocyanurate and potassium iodide react to form iodine species for disinfecting the contact lens. An amount of ascorbate is then added to neutralize the iodine species.
    Type: Grant
    Filed: June 7, 1995
    Date of Patent: January 7, 1997
    Assignee: Alcon Laboratories, Inc.
    Inventors: Ronald L. Schlitzer, N. L. Dassanayake, Rajkumar P. Bhatia
  • Pharmaceutical compositions and methods of treatment of the cornea following laser treatment
    Patent number: 5589184
    Abstract: Methods for preventing and treating corneal haze resulting from exposure of the eye to laser irradiation are disclosed. The methods include administration of compositions of wound healing modulators to the eye. Compositions for use in preventing and treating the corneal haze are also disclosed.
    Type: Grant
    Filed: March 16, 1995
    Date of Patent: December 31, 1996
    Assignee: Alcon Laboratories, Inc.
    Inventors: Stella M. Robertson, Herman M. Kunkle, Jr.
  • Surgical cassette loading and unloading system
    Patent number: 5588815
    Abstract: A surgical cassette unloading and unloading system having a peristaltic pump roller head with a flared and beveled notch and a plunger or probe that engages the cassette peristaltic pump tube.
    Type: Grant
    Filed: November 15, 1995
    Date of Patent: December 31, 1996
    Assignee: Alcon Laboratories, Inc.
    Inventor: Richard L. Zaleski, II
  • Pharmaceutical compositions and methods of treatment of the cornea following laser irradiation
    Patent number: 5589185
    Abstract: Methods for treating the cornea following UV laser irradiation and resulting photoablation of corneal tissue are disclosed. The methods include administration of compositions of a non-steroidal antiinflammatory to the eye. Compositions for use in treating the cornea are also disclosed.
    Type: Grant
    Filed: March 16, 1995
    Date of Patent: December 31, 1996
    Assignee: Alcon Laboratories, Inc.
    Inventors: Stella M. Robertson, Herman M. Kunkle, Jr.
  • Sulfonamides useful as carbonic anhydrase inhibitors
    Patent number: 5585377
    Abstract: Sulfonamides and pharmaceutical compositions containing the compounds useful in controlling intraocular pressure are disclosed. Methods for controlling intraocular pressure through administration of the compositions are also disclosed.
    Type: Grant
    Filed: December 23, 1994
    Date of Patent: December 17, 1996
    Assignee: Alcon Laboratories, Inc.
    Inventors: Thomas R. Dean, Jesse A. May, Hwang-Hsing Chen
  • Automated hand-held keratometer
    Patent number: 5585873
    Abstract: An automated portable keratometer includes a hand held housing and is battery powered. A projection system projects collimated light sources at equal converging angles to an optical axis which extends outside the housing. A camera, including an imaging device, and telocentric objective lens are aligned along the optical axis in the housing. The projection system projects a known pattern of collimated light sources onto a patient's eye. The reflected images of these light sources is captured by the camera and imaging device. Derivation of the distances between certain reflected images can be converted by known algorithms into radii of curvature of the eye. Alignment leveling, and other features can be included with the keratometer. The device can also be used to measure other curved surfaces.
    Type: Grant
    Filed: October 11, 1991
    Date of Patent: December 17, 1996
    Assignee: Alcon Laboratories, Inc.
    Inventors: Tadmor Shalon, Marvin L. Pund