Patents Assigned to Alcon
  • PAI-1 EXPRESSION AND ACTIVITY INHIBITORS FOR THE TREATMENT OF OCULAR DISORDERS
    Publication number: 20090202524
    Abstract: The invention concerns in one embodiment a method for treating glaucoma or elevated IOP in a patient comprising administering to the patient an effective amount of a composition comprising an agent that inhibits PAI-1 expression or PAI-1 activity. Another embodiment of the present invention is a method of treating a PAI-1-associated ocular disorder in a subject in need, comprising administering to the patient an effective amount of a composition comprising an agent that inhibits PAI-1 activity or expression.
    Type: Application
    Filed: April 9, 2009
    Publication date: August 13, 2009
    Applicant: ALCON RESEARCH, LTD.
    Inventors: Debra L. Fleenor, Allan R. Shepard, Iok-Hou Pang, Mark R. Hellberg, Abbot F. Cark
  • Apodized diffractive IOL with frustrated diffractive region
    Patent number: 7572007
    Abstract: In one aspect, the present invention provides a diffractive ophthalmic lens (e.g., a diffractive IOL) that includes an optic having an anterior surface and a posterior surface, where the optic provides a far focus. A frustrated diffractive structure comprising a plurality of diffractive zones is disposed on at least one of those surfaces so as to provide a near focus. Each zone is separated from an adjacent zone by a zone boundary that imparts an optical delay to the incident light. Further, at least two consecutive zone boundaries are configured such that a difference between their associated phase delays for at least one wavelength of the incident light is greater than about ΒΌ wavelength so as to direct a portion of the incident light to a location between the near and far foci.
    Type: Grant
    Filed: August 2, 2006
    Date of Patent: August 11, 2009
    Assignee: Alcon, Inc.
    Inventor: Michael J. Simpson
  • Method of operating an ultrasound handpiece
    Patent number: 7572242
    Abstract: A method of operating an ultrasonic handpiece by pulsing the power supplied to the handpiece and varying the amplitude of the power during the power pulse.
    Type: Grant
    Filed: August 19, 2005
    Date of Patent: August 11, 2009
    Assignee: Alcon, Inc.
    Inventor: Mikhail Boukhny
  • ANTIMICROBIAL N-HALOGENATED AMINO ACID SALTS
    Publication number: 20090197838
    Abstract: The present invention relates to a formulation comprising a N-halogenated amino acid and a phase transfer agent. The present invention also describes a method for disinfecting and/or cleaning a contact lens comprising contacting a contact lens with a formulation comprising a N-halogenated amino acid salt for a time sufficient to disinfect and/or clean the lens.
    Type: Application
    Filed: April 30, 2008
    Publication date: August 6, 2009
    Applicant: ALCON RESEARCH, LTD.
    Inventors: L. Wayne Schneider, Wesley Wehsin Han, Masood A. Chowhan, David W. Stroman, W. Dennis Dean, Michael S. Gaines
  • System and method for identifying and controlling ophthalmic surgical devices and components
    Patent number: 7568619
    Abstract: System and method for identifying a component, such as an optical probe or pneumatic scissors, of an ophthalmic surgical device. A component of a surgical device includes an identifier, such as a RFID tag. Data from the RFID tag is transmitted to a RFID reader in the device. A controller determines whether the component corresponding to the received data is operable with the surgical device based on criteria, such as whether the received data is an authorized code that matches data stored in memory or whether the received data solves or satisfies an algorithm. The authorized codes are selected from a larger set of available codes. The controller enables or disables the operation of the device with the component based on whether the criteria is satisfied, the number of uses of the component, an amount of time that has passed since the component has been used, or a geographic location.
    Type: Grant
    Filed: December 15, 2004
    Date of Patent: August 4, 2009
    Assignee: Alcon, Inc.
    Inventors: Kirk W. Todd, Johan G. Ekvall, Frederick M. Reed, T. Scott Rowe, Christopher Horvath
  • Medical equipment tray system
    Patent number: 7565972
    Abstract: A medical equipment tray system includes a two piece platform, a foldable liner which fits over the two piece platform and a handpiece cradle which may be elevated with respect to the two piece platform.
    Type: Grant
    Filed: June 18, 2007
    Date of Patent: July 28, 2009
    Assignee: Alcon, Inc.
    Inventor: Dennis L. Steppe
  • Multi-spot ophthalmic laser probe
    Patent number: 7566173
    Abstract: A laser probe includes an emitting optical fiber, optics, and two or more receiving optical fibers. The emitting optical fiber emits a beam of laser light. The optics diffract the beam of light emitted by the emitting optical fiber. The receiving optical fibers each receive a beam of light diffracted by the optics.
    Type: Grant
    Filed: July 9, 2007
    Date of Patent: July 28, 2009
    Assignee: Alcon, Inc.
    Inventors: Jack R. Auld, Ronald T. Smith
  • Use of Natriuretic Peptide Receptor Antagonists to Treat Ocular, Otic and Nasal Edemetous Conditions
    Publication number: 20090181896
    Abstract: Methods and compositions to treat edematous ocular, otic and nasal conditions are described.
    Type: Application
    Filed: March 24, 2009
    Publication date: July 16, 2009
    Applicant: ALCON RESEARCH, LTD.
    Inventors: Najam A. Sharif, Parvaneh Katoli
  • USE OF AGENTS THAT PREVENT GENERATION OF AMYLOID AND AMYLOID-LIKE LIPOPROTEINS, AND/OR USE OF AGENTS THAT PROMOTE SEQUESTRATION AND/OR DEGRADATION OF, AND/OR PREVENT NEUROTOXICITY OF SUCH PROTEINS IN THE TREATMENT OF HEARING LOSS AND IMPROVING BODY BALANCE
    Publication number: 20090181893
    Abstract: The present invention provides compositions and methods for treating otic disorders. More specifically, the present invention describes the use of agents that down-regulate expression of Tanis and/or p21Waf1/Cip1/Sd1 genes to treat such disorders of the ear.
    Type: Application
    Filed: March 2, 2009
    Publication date: July 16, 2009
    Applicant: ALCON, INC.
    Inventor: Najam A. Sharif
  • USE OF A COMBINATION OF OLOPATADINE AND CILOMILAST TO TREAT NON-INFECTIOUS RHINITIS AND ALLERGIC CONJUNCTIVITIS
    Publication number: 20090182035
    Abstract: Disclosed are methods of treating allergic conjunctivitis and non-infectious rhinitis in a subject that involve topically administering to the subject a composition comprising olopatadine and cilomilast.
    Type: Application
    Filed: March 18, 2009
    Publication date: July 16, 2009
    Applicant: Alcon Research, Ltd.
    Inventors: John M. Yanni, Daniel A. Gamache, Steven T. Miller, Clay Beauregard
  • Priming a microsurgical system
    Patent number: 7559914
    Abstract: A microsurgical system capable of priming its aspiration circuit using a pressurized gas source, a pressurized infusion fluid source, an aspiration chamber fluidly coupled to the pressurized gas source and the pressurized infusion fluid source, and a computer.
    Type: Grant
    Filed: October 16, 2006
    Date of Patent: July 14, 2009
    Assignee: Alcon, Inc.
    Inventors: David M. Domash, Mark A. Hopkins, John C. Huculak, Nader Nazarifar
  • Caster attachment system
    Patent number: 7552508
    Abstract: A caster attachment system includes an upper section and a lower section. The upper section mounts to a piece of equipment. The lower section provides a post for the mounting of a caster. A shaped key on the lower section fits within a receiver socket on the upper portion. The upper section and the lower section are held together by a threadable connection.
    Type: Grant
    Filed: May 17, 2006
    Date of Patent: June 30, 2009
    Assignee: Alcon, Inc.
    Inventor: John R. Underwood
  • RFID ring illumination system for surgical machine
    Patent number: 7551077
    Abstract: An RFID ring illumination system includes an illumination ring and a printed circuit board. The illumination ring has a light refracting layer integral with the front of a surgical machine. The printed circuit board is located behind and close to the front of the surgical machine. The printed circuit board has an RFID reader antenna and a light source mounted on it. The light emitted by the light source travels through the illumination ring and is visible from the front of the surgical machine.
    Type: Grant
    Filed: July 31, 2006
    Date of Patent: June 23, 2009
    Assignee: Alcon, Inc.
    Inventors: John L. Raybuck, Ronald T. Smith
  • OPHTHALMIC COMPOSITIONS CONTAINING POLYSACCHARIDE/BORATE GELLING SYSTEM
    Publication number: 20090156693
    Abstract: Topical ophthalmic compositions that form a gel or partial gel upon application to the eye are described. The compositions are particularly useful as artificial tears and ocular lubricants, but may also be utilized for the topical delivery of pharmaceutically active compounds to the eye. The compositions contain a polysaccharide/borate gelling system. The polysaccharides that may be utilized contain cis-diol groups and have a structure that is predominately linear, with a slight degree of branching.
    Type: Application
    Filed: February 23, 2009
    Publication date: June 18, 2009
    Applicant: ALCON, INC.
    Inventor: Bahram Asgharian
  • METHOD OF TREATING MIDDLE EAR INFECTIONS
    Publication number: 20090156566
    Abstract: Aqueous suspension formulations containing dexamethasone and ciprofloxacin are disclosed for the treatment of middle ear infections in human patients having an open tympanic membrane.
    Type: Application
    Filed: February 13, 2009
    Publication date: June 18, 2009
    Applicant: Alcon, Inc.
    Inventors: G. Michael Wall, Peter J. Conroy
  • METHOD OF TREATING ASTHMA, ALLERGIC RHINITIS, AND SKIN DISORDERS
    Publication number: 20090156667
    Abstract: The use of 5,6,7-trihydroxyheptanoic acid and analogs is disclosed for the treatment of asthma, allergic rhinitis, and skin disorders such as allergic dermatitis, contact hypersensitivity, urticaria (hives), rosacea, or psoriasis.
    Type: Application
    Filed: February 19, 2009
    Publication date: June 18, 2009
    Applicant: Alcon Research, Ltd.
    Inventors: Peter G. Klimko, Clay Beauregard, Bryon S. Severns
  • 1-ALKYL-3-AMINOINDAZOLES
    Publication number: 20090149659
    Abstract: Methods of making 1-alkylindazoles are described. The methods involve reacting a 2-alkylaminobenzonitrile with a nitrosating agent followed by reduction-cyclization of the resulting nitrosamine to form a 1-alkyl-3-aminoindazole. The 1-alkyl-3-aminoindazole can be deaminated to form a 1-alkylindazole which ultimately can be used to form desired indazoles which are preferably pharmaceutically active products. The process of the present invention further permits the formation of enantiomerically enriched or pure indazoles such as aminoalkyl indazoles.
    Type: Application
    Filed: February 10, 2009
    Publication date: June 11, 2009
    Applicant: Alcon, Inc.
    Inventors: Pete Delgado, Raymond E. Conrow, W. Dennis Dean
  • LOW-TACK OPHTHALMIC AND OTORHINOLARYNGOLOGICAL DEVICE MATERIALS
    Publication number: 20090137745
    Abstract: Disclosed are soft, high refractive index, acrylic materials. These materials, especially useful as intraocular lens materials, contain one or more aryl acrylic hydrophobic monomers as principal device-forming monomers and a tack-reducing macromer additive. In addition to their use as intraocular lens materials, the present materials are also suitable for use in other ophthalmic or otorhinolaryngological devices, such as contact lenses, keratoprostheses, corneal inlays or rings; otological ventilation tubes and nasal implants.
    Type: Application
    Filed: January 23, 2009
    Publication date: May 28, 2009
    Applicant: Alcon,Inc.
    Inventors: Diana M. Cordova, Mutlu Karakelle, Chance Lehman, Douglas C. Schlueter, Joseph I. Weinschenk, III
  • TOPICAL OPHTHALMIC OR OTIC SOLUTION FORMULATIONS CONTAINING MOXIFLOXACIN HYDROCHLORIDE AND DEXAMETHASONE PHOSPHATE
    Publication number: 20090137539
    Abstract: Topical ophthalmic and otic solution compositions of moxifloxacin and dexamethasone phosphate are disclosed.
    Type: Application
    Filed: November 24, 2008
    Publication date: May 28, 2009
    Applicant: Alcon Research, Ltd.
    Inventors: Onkar N. Singh, Suresh C. Dixit, Michael Wall
  • LOW-TACK OPHTHALMIC AND OTORHINOLARYNGOLOGICAL DEVICE MATERIALS
    Publication number: 20090132039
    Abstract: Disclosed are soft, high refractive index, acrylic materials. These materials, especially useful as intraocular lens materials, contain one or more aryl acrylic hydrophobic monomers as principal device-forming monomers and a tack-reducing macromer additive. In addition to their use as intraocular lens materials, the present materials are also suitable for use in other ophthalmic or otorhinolaryngological devices, such as contact lenses, keratoprostheses, corneal inlays or rings; otological ventilation tubes and nasal implants.
    Type: Application
    Filed: January 23, 2009
    Publication date: May 21, 2009
    Applicant: Alcon, Inc.
    Inventors: Diana M. Cordova, Mutlu Karakelle, Chance Lehman, Douglas C. Schlueter, Joseph I. Weinschenk, III