Patents Assigned to Alcon
  • OFF-AXIS ANTI-REFLECTIVE INTRAOCULAR LENSES
    Publication number: 20090018651
    Abstract: Exemplary embodiments provide a coated intraocular lens that has a lens body with a first refractive index and an anti-reflective coating. The coating covers at least a portion of the lens body and has a second index of refraction that is less than the first index of refraction of the lens body. The anti-reflective coating reduces the intensity of reflections produced from off axis light incident on the lens body by at least a factor of 2.5 times and enhancing light transmission.
    Type: Application
    Filed: July 11, 2008
    Publication date: January 15, 2009
    Applicant: ALCON, INC.
    Inventors: Xiaoxiao Zhang, Kamal K. Das
  • Substituted furo[2,3-g]indazoles for the treatment of glaucoma
    Patent number: 7476687
    Abstract: Substituted furo[2,3-g]indazoles for lowering intraocular pressure and treating glaucoma are disclosed.
    Type: Grant
    Filed: November 24, 2004
    Date of Patent: January 13, 2009
    Assignee: Alcon, Inc.
    Inventors: Anura P. Dantanarayana, Jesse Albert May
  • Method of calculating the required lens power for an opthalmic implant
    Patent number: 7476248
    Abstract: A method for calculating the required cylindrical power of a toric implant by using both the measured pre-operative corneal/ocular astigmatism and the predicted surgically-induced astigmatism. The post-operative corneal/ocular astigmatism is predicted using power vector analysis of the surgical technique employed by the surgeon. Such a method provides a more accurate method of calculating the required spherocylindrical refractive power of the implant. The method can be implemented manually, but preferably is automated by implementation on a computer through appropriate software.
    Type: Grant
    Filed: April 6, 2004
    Date of Patent: January 13, 2009
    Assignee: Alcon, Inc.
    Inventors: Blake Harris, James Hoffman, Xin Hong, Xiaoxiao Zhang, Warren E. Hill
  • SUBSTITUTED FURO[2,3-g]INDAZOLES FOR THE TREATMENT OF GLAUCOMA
    Publication number: 20090012291
    Abstract: Substituted furo[2,3-g]indazoles for lowering intraocular pressure and treating glaucoma are disclosed.
    Type: Application
    Filed: September 19, 2008
    Publication date: January 8, 2009
    Applicant: Alcon, Inc.
    Inventors: Anura P. Dantanarayana, Jesse Albert May
  • RNAi-MEDIATED INHIBITIN OF HTRA1 FOR TREATMENT OF MACULAR DEGENERATION
    Publication number: 20090012030
    Abstract: RNA interference is provided for inhibition of HTRA1 mRNA expression for treating patients with an HTRA1-mediated ocular disorder. In particular, methods are provided for treating age-related macular degeneration (AMD) and using interfering RNA molecules that attenuate expression of HTRA1 in patients having AMD or at risk of developing AMD.
    Type: Application
    Filed: July 1, 2008
    Publication date: January 8, 2009
    Applicant: ALCON RESEARCH, LTD.
    Inventors: Jon E. Chatterton, Martin B. Wax, Carmelo Romano, David P. Bingaman
  • Simultaneous proportional control of surgical parameters in a microsurgical system
    Patent number: 7470277
    Abstract: A microsurgical system, and a foot controller for the improved operation of a microsurgical system, are disclosed. A surgeon may use the foot controller to simultaneously control multiple surgical parameters based upon movement of a foot pedal of the foot controller in a single plane of motion.
    Type: Grant
    Filed: September 4, 2002
    Date of Patent: December 30, 2008
    Assignee: Alcon, Inc.
    Inventors: Russell L. Finlay, Christopher C. Jung, John C. Huculak, Paul Essex, Kirk W. Todd
  • Compositions and methods for inhibiting protein on surfaces
    Patent number: 7468344
    Abstract: The use of NIPAM polymers to prevent or reduce the formation of protein deposits on the surfaces of medical devices is described. The invention is particularly directed to reduction of the adsorption of proteins on surfaces of contact lenses and other medical prosthetics.
    Type: Grant
    Filed: August 16, 2007
    Date of Patent: December 23, 2008
    Assignee: Alcon, Inc.
    Inventor: Howard Allen Ketelson
  • METHOD FOR DETECTING MICROBES
    Publication number: 20080305514
    Abstract: The present invention relates to methods for detecting microbes in a sample comprising filtering the sample through a fluid-permeable surface, contacting the surface with a viability stain, scanning the surface for viability stain to form a first scan, contacting the surface with a nucleic acid stain, scanning the surface for nucleic acid stain to form a second scan, and comparing said first scan and said second scan.
    Type: Application
    Filed: April 21, 2008
    Publication date: December 11, 2008
    Applicant: ALCON RESEARCH, LTD.
    Inventors: Kathleen G. Alford, Sheryll H. Handley, Barry A. Schlech, S. Paul Shannon, Ronald L. Smith
  • Tray support arm assembly
    Patent number: 7461825
    Abstract: A tray support arm assembly provides for the positioning of a tray and an attached movable arm in a substantially horizontal orientation with respect to the console portion of a machine for use and a substantially vertical orientation with respect to the console portion of a machine for storage. The tray support arm assembly includes a lockable tray rotation joint, a lockable wrist joint, a lower arm assembly, a lockable elbow joint, an upper assembly and a lockable shoulder joint.
    Type: Grant
    Filed: September 18, 2006
    Date of Patent: December 9, 2008
    Assignee: Alcon, Inc.
    Inventors: Argelio Olivera, David Weston, Andrew M. Hahn
  • Phospholipid Compositions for Contact Lens Care and Preservation of Pharmaceutical Compositions
    Publication number: 20080287395
    Abstract: The use of certain synthetic phospholipids to preserve pharmaceutical compositions from microbial contamination is described. The synthetic phospholipids have unique molecular arrangements wherein a phosphate group is linked to a quaternary ammonium functionality via a substituted-propenyl group, and the quaternary ammonium functionality is further linked to at least one long hydrocarbon chain. Such molecular arrangements are what make the phospholipids of formula (I) highly water soluble, e.g., the length of the hydrocarbon chain assists to maintain solubility and efficacy of the molecules for the uses described herein. The synthetic phospholipids described herein have been found to be particularly useful as antimicrobial preservatives for ophthalmic, otic and nasal pharmaceutical compositions, especially ophthalmic compositions. These compounds may also be utilized to disinfect contact lenses.
    Type: Application
    Filed: May 16, 2008
    Publication date: November 20, 2008
    Applicant: ALCON RESEARCH, LTD.
    Inventors: Malay Ghosh, Masood A. Chowhan, L. Wayne Schneider
  • N-HALOGENATED AMINO ACID FORMULATIONS WITH ANTI-INFLAMMATORY COMPOUNDS
    Publication number: 20080275122
    Abstract: The present invention relates to a formulation having antimicrobial activity comprising a N-halogenated amino acid and a anti-inflammatory compound. This specification also describes methods for treating a tissue infection comprising contacting the infected tissue with a pharmaceutically effective amount of a formulation comprising a N-halogenated amino acid and a anti-inflammatory compound. This specification further describes a method for treating respiratory infections comprising contacting the site of the respiratory infection with a pharmaceutically effective amount of a formulation comprising a N-halogenated amino acid and a anti-inflammatory compound.
    Type: Application
    Filed: April 30, 2008
    Publication date: November 6, 2008
    Applicant: ALCON RESEARCH, LTD.
    Inventors: Masood A. Chowhan, Wesley Wehsin Han
  • N-HALOGENATED AMINO ACID FORMULATIONS AND METHODS FOR CLEANING AND DISINFECTION
    Publication number: 20080275121
    Abstract: The present invention relates to methods for disinfecting or cleaning a contact lens comprising contacting a contact lens with a formulation comprising a N-halogenated amino acid and a phase transfer agent for a time sufficient to disinfect or clean the lens. This specification further discloses a formulation for disinfecting a contact lens comprising an N-halogenated amino acid and a phase transfer agent.
    Type: Application
    Filed: April 30, 2008
    Publication date: November 6, 2008
    Applicant: ALCON RESEARCH, LTD.
    Inventors: Masood A. Chowhan, Wesley Wehsin Han, L. Wayne Schneider, David W. Stroman, Nissanke L. Dassanayake
  • N-HALOGENATED AMINO ACID FORMULATIONS
    Publication number: 20080275123
    Abstract: The present invention relates to a method for treating a tissue infection comprising contacting the infected tissue with a pharmaceutically effective amount of a formulation comprising a N-halogenated amino acid and a phase transfer agent. This specification also describes a formulation having antimicrobial activity comprising a N-halogenated amino acid and a phase transfer agent.
    Type: Application
    Filed: April 30, 2008
    Publication date: November 6, 2008
    Applicant: ALCON RESEARCH, LTD.
    Inventors: Masood A. Chowhan, Nissanke L. Dassanayake, Wesley Wehsin Han, Wayne L. Schneider, David W. Stroman
  • ALIPHATIC ACID-CONTAINING N-HALOGENATED AMINO ACID FORMULATIONS
    Publication number: 20080275126
    Abstract: The present invention relates to methods for treating an infected tissue comprising treating the infected tissue with a formulation comprising a N-halogenated amino acid and an aliphatic acid. This specification also discloses methods for improving the antimicrobial activity of a formulation comprising a N-halogenated amino acid, the method comprising adding an aliphatic acid to said formulation.
    Type: Application
    Filed: April 30, 2008
    Publication date: November 6, 2008
    Applicant: ALCON RESEARCH, LTD.
    Inventors: Masood A. Chowhan, Wesley Wehsin Han, Wayne L. Schneider, David W. Stroman
  • Use of bis-amines to enhance the antimicrobial activity of aqueous compositions
    Patent number: 7445771
    Abstract: The use of bis-amines to enhance the antimicrobial activity of pharmaceutical compositions is described. The bis-amines are particularly useful for enhancing the antimicrobial activity of aqueous ophthalmic compositions, such as artificial tears or ocular lubricants, and solutions for disinfecting contact lenses.
    Type: Grant
    Filed: December 9, 2004
    Date of Patent: November 4, 2008
    Assignee: Alcon, Inc.
    Inventors: Nissanke L. Dassanayake, Thomas Christopher Carey, Ronald L. Schlitzer, David L. Meadows
  • INTRAOCULAR LENS WITH EDGE MODIFICATION
    Publication number: 20080269891
    Abstract: Intraocular lenses (IOLs) with modified edge characteristics are disclosed to inhibit transverse propagation of internally reflected light rays in order to alleviate, and preferably eliminate, dysphotopsia and/or the perception of dark shadows reported by some users. In one embodiment, IOL designs are disclosed that incorporate an opaque edge or other mechanisms for capturing internally reflected peripheral light rays. In other embodiments, the peripheral region can include a light scattering material or can have a disproportional thickness or be contoured to redirect peripheral rays.
    Type: Application
    Filed: April 30, 2007
    Publication date: October 30, 2008
    Applicant: ALCON, INC.
    Inventors: Xin Hong, Xiaoxiao Zhang
  • INTRAOCULAR LENS WITH ASYMMETRIC OPTICS
    Publication number: 20080269882
    Abstract: In one aspect, an intraocular lens (IOL) is discloses that includes an optic having a central portion and a peripheral extension that partially surrounds the central portion. Once implanted in a patient's eye, the IOL's optic forms an image of a field of view with the peripheral extension inhibiting dysphotopsia. While in some embodiments, the peripheral extension provides focusing of light incident thereon, in other embodiments, it can include at least one textured surface for scattering the light or at least one opaque surface for preventing the light from reaching the retina. In other embodiments, the peripheral extension can include one or more translucent surface(s) for diffusing the light passing therethrough to inhibit dysphotopsia.
    Type: Application
    Filed: April 30, 2007
    Publication date: October 30, 2008
    Applicant: ALCON UNIVERSAL LTD.
    Inventors: Michael J. Simpson, Xiaoxiao Zhang
  • GRADUATED BLUE FILTERING INTRAOCULAR LENS
    Publication number: 20080269884
    Abstract: Devices and methods utilizing novel intraocular lens (IOL) designs are discussed herein. One aspect relates to IOLs having an optic with non-uniform light transmissivity. For example, the optic of the IOL can include a central region having a reduced light transmissivity relative to another portion of the optic. In addition, or alternatively, the optic can have a peripheral region having reduced light transmissivity. Such IOLs can potentially be utilized to alter the light distribution impinging on a subject's retina, which can be tailored to specific lighting situations such as bright and dim light conditions. Such IOLs can also, or alternatively, be used to help alleviate the perception of dark shadows known as negative dysphotopsia. Other aspects and features of IOLs, and methods, are also discussed.
    Type: Application
    Filed: April 30, 2008
    Publication date: October 30, 2008
    Applicant: Alcon, Inc.
    Inventor: Stephen J. Vannoy
  • INTRAOCULAR LENS WITH PERIPHERAL REGION DESIGNED TO REDUCE NEGATIVE DYSPHOTOPSIA
    Publication number: 20080269890
    Abstract: In one aspect, the invention provides an intraocular lens (IOL) that includes an optic and a peripheral optical flange that surrounds the optic. The optic can form an image of a field of view on the IOL user's retina and the peripheral flange can inhibit dysphotopsia. By way of example, the peripheral flange can include at least one textured surface that is adapted to receive peripheral light rays entering the eye at large visual angles so as to cause their scattering in order to inhibit dysphotopsia, e.g., by preventing the formation of a secondary peripheral image or scattering some light to a shadow region between such a secondary image and an image formed by the IOL.
    Type: Application
    Filed: April 30, 2007
    Publication date: October 30, 2008
    Applicant: ALCON UNIVERSAL LTD.
    Inventors: Michael J. Simpson, Xiaoxiao Zhang
  • UV-ABSORBERS FOR OPHTHALMIC LENS MATERIALS
    Publication number: 20080266519
    Abstract: 1,4-disubstituted-1,2,3-triazole UV absorbing monomers are disclosed. The UV absorbers are particularly suitable for use in intraocular lens materials.
    Type: Application
    Filed: April 29, 2008
    Publication date: October 30, 2008
    Applicant: ALCON RESEARCH, LTD.
    Inventor: Douglas C. Schlueter