Patents Assigned to Alsius Corporation
  • Patent number: 7425216
    Abstract: A closed loop heat exchange catheter can be placed in a patient suffering from cardiac arrest or myocardial infarction to cool the patient. Or, a heat exchange pad can be placed against the patient's skin to cool the patient. Magnesium sulfate is infused into the patient.
    Type: Grant
    Filed: March 1, 2005
    Date of Patent: September 16, 2008
    Assignee: Alsius Corporation
    Inventor: Kenneth A. Collins
  • Publication number: 20070293921
    Abstract: A patient control system uses a patient-implanted catheter in thermal communication with a fluid bath via a circulating fluid circuit. A controller automatically controls the temperature of the fluid bath as required for selectively cooling or heating the patient in accordance with patient temperature measurements. The controller thermally decouples the catheter and patient from the fluid bath during changes in fluid bath temperatures in order to overcome the effects of system thermal mass.
    Type: Application
    Filed: August 31, 2007
    Publication date: December 20, 2007
    Applicant: Alsius Corporation
    Inventors: Wayne Noda, Scott Evans, Mark Whitebook, David Balding
  • Patent number: 7287398
    Abstract: A cooling system for an indwelling heat exchange catheter includes a heat exchange bath that is configured to receive a conduit that carries saline to and from the catheter. A heating/cooling fluid is in the bath and exchanges heat with the saline. The heating/cooling fluid flows through a heat exchanger that includes a refrigerant and two variable speed DC compressor for removing heat from the refrigerant. A gear pump circulates the working fluid to and from the catheter and is removably engaged with a pump support platform.
    Type: Grant
    Filed: August 6, 2004
    Date of Patent: October 30, 2007
    Assignee: Alsius Corporation
    Inventors: Wayne Noda, Stelica Stelea
  • Patent number: 7278984
    Abstract: A patient control system uses a patient-implanted catheter in thermal communication with a fluid bath via a circulating fluid circuit. A controller automatically controls the temperature of the fluid bath as required for selectively cooling or heating the patient in accordance with patient temperature measurements. The controller thermally decouples the catheter and patient from the fluid bath during changes in fluid bath temperatures in order to overcome the effects of system thermal mass.
    Type: Grant
    Filed: December 31, 2002
    Date of Patent: October 9, 2007
    Assignee: Alsius Corporation
    Inventors: Wayne A. Noda, Scott M. Evans, Mark Evan Whitebook, David P. Balding
  • Patent number: 7255709
    Abstract: An indwelling heat exchange catheter with integrated temperature sensor includes a catheter tube. A closed loop heat exchanger extends from the catheter tube. A temperature sensor can be integrally formed with the catheter tube such that it is insulated from the closed loop heat exchanger. The indwelling heat exchange catheter can further include a guide-wire tube that extends from the catheter tube and in such a case, the temperature sensor can be affixed to the guide-wire tube. Alternatively, a wire can extend through the catheter tube and the temperature sensor can be affixed to the wire.
    Type: Grant
    Filed: August 6, 2004
    Date of Patent: August 14, 2007
    Assignee: Alsius Corporation
    Inventors: Blair D. Walker, Peter Barker, Hortensia Pompa, Xochitl Huezo, Lynn Miyeko Shimada
  • Patent number: 7181927
    Abstract: A system for exchanging heat with primary coolant flowing through an intravascular catheter or externally-applied pad to warm or cool a patient. A secondary heat transfer element can be engaged with a primary heat transfer element and is not grounded when the primary heat transfer element is fully engaged with the secondary heat transfer element during operation. In contrast, the secondary heat transfer element is grounded when the primary heat transfer element is at a predetermined disengaged position relative to the secondary heat transfer element.
    Type: Grant
    Filed: July 1, 2005
    Date of Patent: February 27, 2007
    Assignee: Alsius Corporation
    Inventors: Kenneth A. Collins, David Seari Kimball
  • Patent number: 7144407
    Abstract: An intra-aortic balloon pump catheter system (apparatus and method) includes a pumping element for pumping a patient's blood and one or more heat exchange for exchanging heat with the patient's blood to provide efficient temperature control of the patient. The catheter may also provide access to the patient's central venous system through one or more infusion lumens and infusion ducts. An elongate body defines an inflation lumen that conveys an inflation fluid to and from the pumping element, and an inflow lumen and an outflow lumen that supply heat exchange fluid to and from each heat exchange element. The pumping element may include an everting pumping balloon that expands out of a cavity in the elongate body after insertion of the catheter. The catheter may have an internal heating element that heats or cools the heat exchange fluid.
    Type: Grant
    Filed: May 30, 2002
    Date of Patent: December 5, 2006
    Assignee: Alsius Corporation
    Inventor: Jack W. Lasersohn
  • Patent number: 7101388
    Abstract: A system for exchanging heat with the body of a patient for cooling or warming the patient provides for automatic temperature control in accordance with the monitored temperature of the patient. The system comprises a temperature control module and temperature probes for making body core temperature measurements. The body core temperature measurements are used to control the temperature of fluid circulating within the fluid circuit.
    Type: Grant
    Filed: July 29, 2004
    Date of Patent: September 5, 2006
    Assignee: Alsius Corporation
    Inventors: Wayne A. Noda, William J. Worthen
  • Patent number: 7097657
    Abstract: A fluid circuit for circulating coolant in a closed loop between an intravascular catheter and a heat exchange system includes a buffer IV bag in fluid flow series with the catheter between the catheter and a pump that pumps the coolant to the heat exchange system. A conventional IV bag is connected by means of a spike and tube to the buffer bag.
    Type: Grant
    Filed: February 18, 2003
    Date of Patent: August 29, 2006
    Assignee: Alsius Corporation
    Inventors: Wayne Arthur Noda, Lynn M. Shimada
  • Patent number: 7090792
    Abstract: A group of multiple hollow fibers may be shaped to introduce angular divergence among the fibers, or to introduce a selected longitudinal oscillation into the fibers. In one shaping technique, the fibers are held in parallel while upper and lower crimping assemblies of parallel crimping bars are drawn together on opposite sides of the parallel fibers. When bars of the opposing assemblies draw sufficiently close, they sandwich the fibers in between them, causing each fiber to assume a shape that oscillates as the fiber repeatedly goes over and then under successive bars. Since the crimping bars are aligned at oblique angles to the fibers, the peaks and troughs of successive fibers are offset. While in this position, the fibers are heated and then cooled to permanently retain their shapes. A different shaping technique utilizes a lattice of criss-crossing tines defining multiple apertures. In this technique, the lattice and fibers are positioned so that each fiber passes through one of the apertures.
    Type: Grant
    Filed: November 2, 2000
    Date of Patent: August 15, 2006
    Assignee: Alsius Corporation
    Inventors: David P. Balding, Steven C. Foster
  • Patent number: 7070612
    Abstract: An intravenous heat exchange catheter and/or an external cooling pad/bladder can be used to maintain hypothermia in, e.g., a cardiac arrest patient, but to accelerate the cooling process the patient first can be infused with cold saline before the opportunity arises to connect the catheter or pad to the patient.
    Type: Grant
    Filed: April 18, 2005
    Date of Patent: July 4, 2006
    Assignee: Alsius Corporation
    Inventors: Kenneth A. Collins, William J. Worthen
  • Patent number: 7014651
    Abstract: A method for treating cardiac arrest includes defibrillating the patient and/or ventilating the patient and/or administering a cardiac arrest drug such as epinephrine to resuscitate the patient, and then cooling the patient using one or more cooling catheter positioned in the central venous system of the patient.
    Type: Grant
    Filed: June 27, 2002
    Date of Patent: March 21, 2006
    Assignee: Alsius Corporation
    Inventors: William J. Worthen, Scott M. Evans, Suzanne C Winter, David Balding
  • Patent number: 7001418
    Abstract: Various types of insulated coolant lines that extend between a heat exchanger and an intravascular heat exchange catheter are disclosed.
    Type: Grant
    Filed: April 30, 2003
    Date of Patent: February 21, 2006
    Assignee: Alsius Corporation
    Inventor: Wayne Arthur Noda
  • Patent number: 6942644
    Abstract: A catheter with three spiral heat exchange elements surrounding a central supply tube and communicating with a source of heat exchange fluid in a closed loop for effecting patient temperature control and at least two infusion lumens for providing access to the central venous blood supply when the catheter is placed in the central venous system. An anchor can be provided to suture or tape the catheter to the skin of a patient.
    Type: Grant
    Filed: March 31, 2003
    Date of Patent: September 13, 2005
    Assignee: Alsius Corporation
    Inventor: William J. Worthen
  • Patent number: 6893454
    Abstract: A closed loop heat exchange catheter can be placed in the rectum of a patient to cool or warm the patient.
    Type: Grant
    Filed: April 28, 2003
    Date of Patent: May 17, 2005
    Assignee: Alsius Corporation
    Inventor: Kenneth A. Collins
  • Patent number: 6878156
    Abstract: A portable cooler is provided for heat exchange catheters that is powered by one or more batteries. The cooler can include Rankine cycle compressor components or thermoelectric cooler (TEC) components. The cooler can be carried in an ambulance and used to support coolant to an indwelling heat exchange catheter that is placed in the patient's venous system to prevent fever and/or induce therapeutic moderate hypothermia in, e.g., stroke victims, heart attack victims, and cardiac arrest victims.
    Type: Grant
    Filed: July 26, 2002
    Date of Patent: April 12, 2005
    Assignee: Alsius Corporation
    Inventor: Wayne Arthur Noda
  • Patent number: 6872222
    Abstract: Insulating foam or other material is disposed between an intravascular heat exchange catheter and the skin of a patient to alleviate patient discomfort arising from the catheter being hotter or colder than skin temperature.
    Type: Grant
    Filed: May 19, 2003
    Date of Patent: March 29, 2005
    Assignee: Alsius Corporation
    Inventors: Xia Luo, Lynn Miyeko Shimada
  • Publication number: 20050028551
    Abstract: A cooling system for an indwelling heat exchange catheter includes a heat exchange bath that is configured to receive a conduit that carries saline to and from the catheter. A heating/cooling fluid is in the bath and exchanges heat with the saline. The heating/cooling fluid flows through a heat exchanger that includes a refrigerant and two variable speed DC compressor for removing heat from the refrigerant. A gear pump circulates the working fluid to and from the catheter and is removably engaged with a pump support platform.
    Type: Application
    Filed: August 6, 2004
    Publication date: February 10, 2005
    Applicant: Alsius Corporation
    Inventors: Wayne Noda, Stelica Stelea
  • Publication number: 20050033391
    Abstract: A closed loop heat exchange catheter can be placed in a patient suffering from cardiac arrest or myocardial infarction to cool the patient. Oxygen is infused into the patient to provide extra oxygen to the heart. Both modalities reduce infarct volume.
    Type: Application
    Filed: August 6, 2004
    Publication date: February 10, 2005
    Applicant: Alsius Corporation
    Inventors: William Worthen, Kenneth Collins
  • Publication number: 20050010273
    Abstract: An indwelling heat exchange catheter with integrated temperature sensor includes a catheter tube. A closed loop heat exchanger extends from the catheter tube. A temperature sensor can be integrally formed with the catheter tube such that it is insulated from the closed loop heat exchanger. The indwelling heat exchange catheter can further include a guide-wire tube that extends from the catheter tube and in such a case, the temperature sensor can be affixed to the guide-wire tube. Alternatively, a wire can extend through the catheter tube and the temperature sensor can be affixed to the wire.
    Type: Application
    Filed: August 6, 2004
    Publication date: January 13, 2005
    Applicant: Alsius Corporation
    Inventors: Blair Walker, Peter Barker, Hortensia Pompa, Xochitl Huezo, Lynn Shimada