Abstract: The novel compounds of formula I: ##STR1## (R.sup.1, R.sup.2 and Hal are defined in the specification) show selective fungicidal activity. The new compounds are processed with carriers and adjuvants to fungicidal compositions.
Abstract: This intention provides a method for enhancing a cell mediates immune response to Mycoplasma hypneumoniae in a newborn swine which involves administering a vaccine containing an effective amount of a protective antibody-inducing antigen to a pregnant sow, following by administering the vaccine to the newborn swine.
Type:
Grant
Filed:
May 25, 1995
Date of Patent:
September 5, 2000
Assignee:
American Cyanamid Company
Inventors:
Balbir S. Bhogal, Krishnaswamy I. Dayalu, Jay D. Gerber
Abstract: The present invention provides a process to prepare a pyridine-2,3-dicarboxylate derivative via the reaction of a dialkyl alkoxy(or alkylthio)oxalacetate with an appropriately substituted acrolein compound in the presence of an ammonia source and a solvent. The present invention also provides useful intermediate compounds of formula IV.
Abstract: The present invention relates to methods for controlling and/or treating RNA-replicating viral infections which afflict human beings, animals and/or plants. Specifically, the RNA chain terminating agents, 3'-deoxyribouracil, 3'-deoxyriboguanine and 3'-deoxyribocytosine are useful in treating RNA-replicating viral infections.
Abstract: The novel cyanopyridines of the general formula (I) ##STR1## (A, B, R.sup.1, R.sup.2, X, m and n are defined in the specification) show selective herbicidal activity.The new compounds can be prepared according to known methods and can be used as herbicides in agriculture and related fields.
Type:
Grant
Filed:
July 15, 1999
Date of Patent:
August 29, 2000
Assignee:
American Cyanamid Company
Inventors:
Thomas Maier, Stefan Scheiblich, Helmut Siegfried Baltruschat
Abstract: This invention discloses methods for identifying compounds, variant nuclear proteins and other auxiliary proteins that interfere with the Drosophila ultraspiracle protein ("Usp") and homologs thereof. The methods disclosed involve transformed yeast cells which contain a Usp binding partner, Usp or a homolog thereof which can bind with the Usp binding partner, and a reporter gene which requires a functional Usp--Usp binder partner complex for expression. The transformed yeast cells are incubated in the presence of a test compound to form a test culture and in the absence of a test compound to form a control culture. The expression of the reporter gene is monitored in one example by exposing the test and control cultures to canavanine under conditions in which control cultures exhibit reduced growth and detecting test cultures in which growth is increased relative to growth of control cultures.
Type:
Grant
Filed:
May 30, 1997
Date of Patent:
August 29, 2000
Assignee:
American Cyanamid Company
Inventors:
Julia N. Heinrich, Fernando Dela E. Cruz, Donald R. Kirsch
Abstract: A liquid concentrated fungicidal composition containing a fungicidally acceptable carrier and/or surface active agent and synergistically effective amounts of(a) at least one acrylic acid morpholide of formula I ##STR1## in which R.sup.1 and R.sup.2 have the meaning given in claim 1, and (b) at least one fungicidal N-pyridylaniline compound. This invention also includes a method of controlling the growth of phythopathogenic fungi at a locus which comprises applying synergistically effective amounts of at least one acrylic acid morpholide of formula I and at least one fungicidal N-pyridylaniline compound to the locus.
Abstract: The novel compounds of formula I: wherein R.sup.1, R.sup.2, R.sup.3, R.sup.4 and Ar have the meaning given in claim 1, and herbicidal compositions containing such compounds as active ingredients.
Abstract: The invention relates a concentrated liquid fungicidal composition comprising a fungicidally acceptable carrier and/or surface active agent and(a) at least one compound of formula I, ##STR1## (b) one or more additional fungicidal active ingredients, which exist as a suspension of fire particles;(c) a solubilizing agent; and(d) a dispersing agent, which has the capability to adsorb irreversibly on the surfaces of hydrophobic particles suspended in water or polar organic solvents.
Type:
Grant
Filed:
April 20, 1998
Date of Patent:
August 1, 2000
Assignee:
American Cyanamid Company
Inventors:
Michael Perlitz, Friedrich Schmidt, Annerose Edith Elise Rehnig, Ewald Gerhard Sieverding, Christopher William Horsler
Abstract: The present invention provides solid agricultural compositions which produce stable dispersions in the presence of polyacrylamide drift control agents.The present invention also provides stable, aqueous dispersions which are produced from the solid compositions of this invention.
Type:
Grant
Filed:
March 19, 1999
Date of Patent:
July 25, 2000
Assignee:
American Cyanamid Company
Inventors:
Volker Dietrich Arendt, Sandra Christine Miller
Abstract: The present invention provides a composition for attracting termites containing a steroid derivative of formula I ##STR1## The present invention also provides a method for attracting or controlling termites with the composition.
Abstract: The invention relates to fungicidal compositions comprising synergistically effective amounts ofat least one acrylic acid morpholide of formula I ##STR1## in which R.sup.1 and R.sup.2 have the meaning given in claim 1 and at least one fungicidal oxazolidinone of formula II ##STR2## in which R.sup.3.sub.1 R.sup.4 and Ar have the meaning given in claim 1, and to a method of controlling the growth of phythopathogenic fungi and/or the plant disease caused by them at a locus which comprises applying synergistically effective amounts of at least one acrylic acid morpholide of formula I (a) and at least one fungicidal compound of formula II (b) to the locus, together with a fungicidally acceptable carrier and/or surface active agent.
Abstract: A container for use in a closed application system includes a valve mounted to a discharge opening of the container and rotatable with the container for controlling the discharge of material from the container. The valve includes an element for engaging corresponding structure in a receptacle for receiving the contents of the container. The element engages and locks the valve in the receptacle when the valve is opened and the contents are being discharged from the container into the receptacle. The valve element and the corresponding structure on the receptacle cooperate so that the container can only be received in and removed from the receptacle when the valve is closed. In this manner, the contents in the container can be discharged only when the container is received within the receptacle and the container is rotated in a direction to open the valve.
Abstract: There is provided a process for the preparation of unsymmetrical 4,6-bis(aryloxy)pyrimidine compounds. The unsymmetrical 4,6-bis(aryloxy)pyrimidine compounds are useful as pesticidal agents.
Type:
Grant
Filed:
March 16, 1999
Date of Patent:
July 11, 2000
Assignee:
American Cyanamid Company
Inventors:
William Wakefield Wood, Salvatore John Cuccia, Robert Brigance
Abstract: The invention relates to a process for the preparation of heteroarylcarboxylic amides and esters of formula I ##STR1## in which one or two of the groups A.sup.1, A.sup.2, A.sup.3, A.sup.4, and A.sup.5 represent a nitrogen atom and the other groups each independently represent CR.sup.3,Hal represent s a halogen atom,X represents oxygen or NR.sup.2,R.sup.1 represents an optionally substituted alkyl, aryl, heteroaryl or cycloalkyl group,R.sup.2 represents a hydrogen atom or an alkyl group, orR.sup.1 and R.sup.2 together with the interjacent ring form a heterocyclic group, andR.sup.3 each independently represent a hydrogen atom or an alkyl group,which comprises heating a mixture of a compound of formula II, ##STR2## and concentrated sulfuric acid, and reacting the resulting intermediate with in alcohol or amine of formula IIIHXR.sup.1 III.
Type:
Grant
Filed:
July 17, 1998
Date of Patent:
July 11, 2000
Assignee:
American Cyanamid Company
Inventors:
Marcus Knell, Monika Brink, Jan Hendrik Wevers, Willi Heinz
Abstract: The present invention provides a process to prepare a pyridine-2,3-dicarboxylate derivative via the reaction of a dialkyl alkoxy(or alkylthio)oxalacetate with an appropriately substituted acrolein compound in the presence of an ammonia source and a solvent.The present invention also provides useful intermediate compounds of formula IV.
Abstract: The present invention relates to a method for isolating and cloning receptor DNA sequences. The invention also provides novel DNA sequences encoding a novel somatostatin receptor subtype.
Type:
Grant
Filed:
May 8, 1997
Date of Patent:
June 20, 2000
Assignee:
American Cyanamid Company
Inventors:
John Richard Hadcock, Bradley Alton Ozenberger, Mark Henry Pausch
Abstract: The present invention provides a method for the protection of wood, wood products and wooden structures from wood-eating insect attack and infestation which comprises treating said wood, wood product or wooden structure or the soil surrounding said wood, wood product or wooden structure with an insecticidally effective amount of an arylpyrrole compound of formula I.
Abstract: Compounds are provided having the following formula: ##STR1## wherein R, R.sub.1, R.sub.2, R.sub.3, and R.sub.4 are defined in the specification, which have matrix metalloproteinase inhibiting activity.
Type:
Grant
Filed:
May 26, 1999
Date of Patent:
June 6, 2000
Assignee:
American Cyanamid Company
Inventors:
Jay D. Albright, Efren G. Delos Santos, Xuemei Du