Abstract: This invention relates to compounds useful for treating fungal infections, more specifically topical treatment of onychomycosis and/or cutaneous fungal infections. This invention is directed to compounds that are active against fungi and have properties that allow the compound, when placed in contact with a patient, to reach the particular part of the skin, nail, hair, claw or hoof infected by the fungus. In particular the present compounds have physiochemical properties that facilitate penetration of the nail plate.
Type:
Grant
Filed:
April 30, 2013
Date of Patent:
November 18, 2014
Assignee:
Anacor Pharmaceuticals, Inc.
Inventors:
Stephen J. Baker, Tsutomu Akama, Carolyn Bellinger-Kawahara, Vincent S. Hernandez, Karin M. Hold, James J. Leyden, Kirk R. Maples, Jacob J. Plattner, Virginia Sanders, Yong-Kang Zhang
Abstract: This invention relates to, among other items, benzoxaborole compounds and their use for treating bacterial infections.
Type:
Application
Filed:
March 21, 2014
Publication date:
October 23, 2014
Applicant:
Anacor Pharmaceuticals, Inc.
Inventors:
Vincent S. HERNANDEZ, Charles Ding, Jacob J. Plattner, Michael Richard Kevin Alley, Fernando Rock, Suoming Zhang, Eric Easom, Xianfeng Li, Ding Zhou
Abstract: This invention provides novel compounds, methods of using the compounds, and pharmaceutical formulations comprising the compounds.
Type:
Grant
Filed:
November 16, 2012
Date of Patent:
October 7, 2014
Assignee:
Anacor Pharmaceuticals, Inc.
Inventors:
Tsutomu Akama, Terry William Balko, Jean Marie Defauw, Jacob J. Plattner, William Hunter White, Joseph Raymond Winkle, Yong-Kang Zhang, Yasheen Zhou
Abstract: This invention relates to compounds useful for treating fungal infections, more specifically topical treatment of onychomycosis and/or cutaneous fungal infections. This invention is directed to compounds that are active against fungi and have properties that allow the compound, when placed in contact with a patient, to reach the particular part of the skin, nail, hair, claw or hoof infected by the fungus. In particular the present compounds have physiochemical properties that facilitate penetration of the nail plate.
Type:
Application
Filed:
March 7, 2014
Publication date:
August 7, 2014
Applicant:
Anacor Pharmaceuticals, Inc.
Inventors:
Stephen J. BAKER, Tsutomu Akama, Michael Richard Kevin Alley, Stephen J. Benkovic, Michael Dipierro, Vincent S. Hernandez, Karin M. Hold, Isaac Kennedy, Igor Likhotvorik, Weimin Mao, Kirk Maples, Jacob J. Plattner, Fernando Rock, Virginia Sanders, Aaron M. Stemphoski, George Petros Yiannikouros, Siead Zagar, Yong-Kang Zhang, Huchen Zhou
Abstract: Compounds, pharmaceutical formulations, and methods of treating anti-inflammatory conditions and/or helminth-associated diseases are disclosed.
Abstract: This invention relates to compounds useful for treating fungal infections, more specifically topical treatment of onychomycosis and/or cutaneous fungal infections. This invention is directed to compounds that are active against fungi and have properties that allow the compound, when placed in contact with a patient, to reach the particular part of the skin, nail, hair, claw or hoof infected by the fungus. In particular the present compounds have physiochemical properties that facilitate penetration of the nail plate.
Type:
Application
Filed:
January 27, 2014
Publication date:
May 22, 2014
Applicant:
ANACOR PHARMACEUTICALS, INC.
Inventors:
Stephen J. Baker, Tsutomu Akama, Carolyn Bellinger-Kawahara, Vincent S. Hernandez, Karin M. Hold, James J. Leyden, Kirk R. Maples, Jacob J. Plattner, Virginia Sanders, Yong-Kang Zhang
Abstract: This invention relates to compounds useful for treating fungal infections, more specifically topical treatment of onychomycosis and/or cutaneous fungal infections. This invention is directed to compounds that are active against fungi and have properties that allow the compound, when placed in contact with a patient, to reach the particular part of the skin, nail, hair, claw or hoof infected by the fungus. In particular the present compounds have physiochemical properties that facilitate penetration of the nail plate.
Type:
Grant
Filed:
January 23, 2012
Date of Patent:
May 13, 2014
Assignee:
Anacor Pharmaceuticals, Inc.
Inventors:
Stephen J. Baker, Tsutomu Akama, Michael Richard Kevin Alley, Stephen J. Benkovic, Michael Dipierro, Vincent S. Hernandez, Karin M. Hold, Isaac Kennedy, Igor Likhotvorik, Weimin Mao, Kirk Maples, Jacob J. Plattner, Fernando Rock, Virginia Sanders, Aaron M. Stemphoski, George Petros Yiannikouros, Siead Zagar, Yong-Kang Zhang, Huchen Zhou
Abstract: Compounds, pharmaceutical formulations, and methods of treating anti-inflammatory conditions and/or helminth-associated diseases are disclosed.
Abstract: This invention relates to, among other items, benzoxaborole compounds and their use for treating bacterial infections.
Type:
Grant
Filed:
September 7, 2011
Date of Patent:
April 22, 2014
Assignee:
Anacor Pharmaceuticals, Inc.
Inventors:
Vincent S. Hernandez, Charles Ding, Jacob J. Plattner, Michael Richard Kevin Alley, Fernando Rock, Suoming Zhang, Eric Easom, Xianfeng Li, Ding Zhou
Abstract: This invention provides, among other things, novel compounds useful for treating protozoal infections, pharmaceutical compositions containing such compounds, as well as combinations of these compounds with at least one additional therapeutically effective agent.
Type:
Grant
Filed:
March 18, 2011
Date of Patent:
January 7, 2014
Assignee:
Anacor Pharmaceuticals, Inc.
Inventors:
Robert T. Jacobs, Daitao Chen, Matthew Orr, Jacob J. Plattner
Abstract: Methods of treating anti-inflammatory conditions through the use of boron-containing small molecules are disclosed.
Type:
Application
Filed:
July 30, 2013
Publication date:
November 28, 2013
Applicant:
ANACOR PHARMACEUTICALS, INC.
Inventors:
Stephen J. Baker, Virginia Sanders, Tsutomu Akama, Carolyn Bellinger-Kawahara, Yvonne Freund, Kirk R. Maples, Jacob J. Plattner, Yong-Kang Zhang, Huchen Zhou, Vincent S. Hernandez
Abstract: This invention provides novel compounds, methods of using the compounds, and pharmaceutical compositions containing the compounds.
Type:
Grant
Filed:
November 16, 2012
Date of Patent:
October 1, 2013
Assignees:
Eli Lilly and Company, Anacor Pharmaceuticals, Inc.
Inventors:
Tsutomu Akama, Terry William Balko, Jean Marie Defauw, Jacob J. Plattner, William Hunter White, Joseph Raymond Winkle, Yong-Kang Zhang, Yasheen Zhou
Abstract: This invention relates to compounds useful for treating fungal infections, more specifically topical treatment of onychomycosis and/or cutaneous fungal infections. This invention is directed to compounds that are active against fungi and have properties that allow the compound, when placed in contact with a patient, to reach the particular part of the skin, nail, hair, claw or hoof infected by the fungus. In particular the present compounds have physiochemical properties that facilitate penetration of the nail plate.
Type:
Application
Filed:
April 30, 2013
Publication date:
September 19, 2013
Applicant:
ANACOR PHARMACEUTICALS, INC.
Inventors:
Stephen J. Baker, Tsutomu Akama, Carolyn Bellinger-Kawahara, Vincent S. Hernandez, Karin M Hold, James J. Leyden, Kirk R. Maples, Jacob J. Plaitner, Virginia Sanders, Yong-Kang Zhang
Abstract: This invention provides, among other things, novel compounds useful for treating protozoal infections, pharmaceutical compositions containing such compounds, as well as combinations of these compounds with at least one additional therapeutically effective agent.
Type:
Application
Filed:
March 18, 2011
Publication date:
September 5, 2013
Applicant:
ANACOR PHARMACEUTICALS, INC.
Inventors:
Robert T. Jacobs, Daitao Chen, Matthew Orr, Jacob J. Plattner
Abstract: This invention relates to compounds useful for treating fungal infections, more specifically topical treatment of onychomycosis and/or cutaneous fungal infections. This invention is directed to compounds that are active against fungi and have properties that allow the compound, when placed in contact with a patient, to reach the particular part of the skin, nail, hair, claw or hoof infected by the fungus. In particular the present compounds have physiochemical properties that facilitate penetration of the nail plate.
Abstract: Methods of treating anti-inflammatory conditions through the use of boron-containing small molecules are disclosed.
Type:
Grant
Filed:
April 23, 2012
Date of Patent:
August 6, 2013
Assignee:
Anacor Pharmaceuticals, Inc.
Inventors:
Stephen J. Baker, Virginia Sanders, Tsutomu Akama, Carolyn Bellinger-Kawahara, Yvonne Freund, Kirk R. Maples, Jacob J. Plattner, Yong-Kang Zhang, Huchen Zhou, Vincent S. Hernandez
Abstract: This invention provides, among other things, novel compounds useful for treating inflammatory conditions, pharmaceutical compositions containing such compounds, as well as combinations of these compounds with at least one additional therapeutically effective agent.
Abstract: This invention provides, among other things, polymorphs of the hydrochloride salt of (S)-3-aminomethyl-7-(3-hydroxy-propoxy)-3H-benzo[c][1,2]oxaborol-1-ol.
Type:
Grant
Filed:
December 17, 2009
Date of Patent:
June 11, 2013
Assignees:
GlaxoSmithKline LLC, Anacor Pharmaceuticals, Inc.
Inventors:
Conrad Wheeler, Dan Todd, Pingyun Chen, Beth A. Norton
Abstract: Compounds and methods of treating anti-inflammatory conditions are disclosed.
Type:
Grant
Filed:
September 19, 2011
Date of Patent:
June 11, 2013
Assignee:
Anacor Pharmaceuticals, Inc.
Inventors:
Tsutomu Akama, Yong-Kang Zhang, Charles Z. Ding, Jacob J. Plattner, Kirk R. Maples, Yvonne Freund, Virginia Sanders, Yi Xia, Stephen J. Baker, James A. Nieman, Xiaosong Lu, Marcelo Sales, Rashmi Sharma, Rajeshwar Singh, Robert T. Jacobs, Daitao Chen, Michael Richard Kevin Alley
Abstract: This invention relates to, among other items, 6-substituted benzoxaborole compounds and their use for treating bacterial infections.
Type:
Grant
Filed:
November 11, 2010
Date of Patent:
June 11, 2013
Assignee:
Anacor Pharmaceuticals, Inc.
Inventors:
Vincent S. Hernandez, Xianfeng Li, Suoming Zhang, Tsutomu Akama, Yanchen Zhang, Yang Liu, Jacob J. Plattner, Michael Richard Kevin Alley, Yasheen Zhou, James A. Nieman