Abstract: The present disclosure provides pharmaceutical compositions comprising fibronectin based scaffold domain proteins that bind, for example, proprotein convertase subtilisin kexin-9 (PCSK9).

Abstract: A system including a processor and a memory, the memory including instructions to be executed by the processor to determine map data, determine uncalibrated LIDAR data, determine a location of a vehicle in the map data by combining the map data with the uncalibrated LIDAR data, and operate the vehicle based on the location of the vehicle in the map data.

Abstract: A fiber optic cassette includes a body defining a front and an opposite rear. A cable entry location is defined on the body for a cable to enter the cassette, wherein a plurality of optical fibers from the cable extend into the cassette and form terminations at non-conventional connectors adjacent the front of the body. A flexible substrate is positioned between the cable entry location and the non-conventional connectors adjacent the front of the body, the flexible substrate rigidly supporting the plurality of optical fibers. Each of the non-conventional connectors adjacent the front of the body includes a ferrule, a ferrule hub supporting the ferrule, and a split sleeve surrounding the ferrule.

Abstract: A semiconductor package assembly has a leadframe that includes a socket member into which solderless pins may be inserted as interconnects to an external component. The cost of manufacturing such a leadframe is reduced without sacrificing the ability to make solderless connections with external components such as PCBs. For example, instead of using a hard material that requires two stamping tools, the leadframes with female sockets may be made using softer copper-based materials. Moreover, the width of such leadframes is significantly smaller than the width of a leadframe with the press-fit pins included. Such a reduced width may further reduce manufacturing costs.

Abstract: A communication system is disclosed. The system can include a first communication unit including a first antenna, a second communication unit including a second antenna and a dielectric waveguide cable, and a rotary joint configured to enable the first unit to rotate with respect to the second unit about an axis of rotation of the system. The dielectric waveguide cable can extend from the second antenna to the rotary joint, where a proximal end of the cable can be coupled to the second antenna and a distal end of the cable can be affixed to the second unit at a location bordering a space defined by the rotary joint. The first and second units can be configured to engage in two-way communication with each other. An axis of the distal end of the cable can be substantially aligned with the axis of rotation of the system.

Abstract: A method of forming stacked semiconductor device structure includes providing a first semiconductor device and a second semiconductor device. The first semiconductor device includes a recessed region bounded by sidewall portions and a conductive layer disposed adjoining at least portions of the recessed region. The method includes electrically connecting the second semiconductor device to the conductive layer within the recessed region such that at least a portion of the second semiconductor device is disposed within the recessed region.

Abstract: In one embodiment, a product includes a plurality of carbon nanotubes and a fill material in interstitial spaces between the carbon nanotubes for limiting or preventing fluidic transfer between opposite sides of the product except through interiors of the carbon nanotubes. Moreover, the longitudinal axes of the carbon nanotubes are substantially parallel, where an average inner diameter of the carbon nanotubes is about 20 nanometers or less. In addition, the ends of the carbon nanotubes are open and the fill material is impermeable or having an average porosity that is less than the average inner diameter of the carbon nanotubes.

Abstract: The present disclosure includes methods of forming air bearing surfaces having multi-tier structures using nanoimprint technology and/or 3D printing technology. In some embodiments, a single stage of milling can be used to transfer a multi-tier photoresist pattern into a substrate (e.g., an AlTiC substrate).

Abstract: In some embodiments, apparatuses and methods are provided herein useful to forecasting product demand. In some embodiments, a system comprise a forecasting control circuit to: apply each of a plurality of different models to forecast demand of a first product over a first historic period generating historic forecasted demands of the first product, wherein at least a first model uses selected one or more variables that are predicted to have an uncharacteristic effect on predicted demand; select one of the models and apply the model in generating a forecasted future demand, wherein the selection of the model is based on a difference between each of the generated historic forecasted demands and actual sales; and identify actions to modify inventory of the first product at the first shopping facility based on the forecasted future demand.

Abstract: An apparatus, including a computer, wherein the computer detects a posting of information regarding a gaming activity, gambling activity, or sporting event, and transmits a notification message to a first communication device associated with an individual. The computer receives a bet message transmitted from the first communication device or a second communication device which includes a global positioning device. The bet message contains information regarding a bet and position or location information regarding a location of the first communication device or the second communication device or position or location information is transmitted to and received at the computer. The computer determines if the bet is allowed or disallowed using the position or location information. If the bet is allowed, the computer processes information for placing the bet. If bet is disallowed, the computer processes information for disallowing the bet.

Abstract: An absorbent article is provided with microencapsulated phase change material (microPCM) particles that are embedded in and/or coated onto a layer of the absorbent article that includes a resilient sheet of an open-cell foam. The foam layer is disposed such that it is in contact with or is in proximity to the user. The microPCM particles absorb heat generated during use of the absorbent article to reduce the contact temperature on the inside of the absorbent article and improve the comfort of the user. To maximize comfort, the phase change temperature of the microPCM particles may be an average normal body temperature.

Abstract: A computer system generates a lattice structure effective to satisfy static loading criteria, the lattice structure including surfaces, nodes, and branches interconnecting nodes. The branches are removed and various alternative configurations are tested to identify one that meets low frequency damping requirements. An outer damping layer is selected to satisfy high frequency damping requirements and is added to the lattice structure. The lattice structure may then be fabricated using an additive manufacturing device.

Abstract: Example magnetic resonance imaging (MRI) radio frequency (RF) coils employ flexible coaxial cable. An MRI RF coil may include an LC circuit and an integrated decoupling circuit. The LC circuit includes one or more flexible coaxial cables having a first end and a second end, the one or more flexible coaxial cables having an inner conductor, an outer conductor, and a dielectric spacer disposed between the inner conductor and the outer conductor, where the outer conductor of the coaxial cable is not continuous between the first end and the second end at a first location. The integrated decoupling circuit may include a PIN diode and a tunable element. The tunable element may be tunable with respect to resistance, capacitance, or inductance, and thus may control, at least in part, the frequency at which the LC circuit resonates during RF transmission, or an impedance at the first location.

Abstract: A compressible adjunct for use with a surgical instrument including a staple cartridge includes a biocompatible layer and a plurality of biocompatible looping members. The biocompatible looping members protrude from the biocompatible layer. Each biocompatible looping member includes a first end portion attached to the biocompatible layer, a second end portion attached to the biocompatible layer, and an intermediate curved portion extending between the first end portion and the second end portion, wherein the intermediate curved portion is further away from the biocompatible layer than the first end portion and the second end portion.

Abstract: Copper electroplating baths include reaction products of amines and polyacrylamides. The reaction products function as levelers and enable copper electroplating baths which have high throwing power and provide copper deposits with reduced nodules.

Abstract: A method, autonomous system controller, and computer program product generate a first route for an autonomous vehicle to transport a first person from a first location to a destination. In response to determining that a second person satisfies trigger criteria comprising: (i) being at a second location that is within a proximity threshold to the first route; (ii) being associated with the first person; and (iii) being associated with the destination, an affordance is caused to be presented via respective user interface devices to at least one of the first and second persons that proposes that the autonomous vehicle transport both the first and second persons to the destination. In response to receiving acceptance, a second route is generated for the autonomous vehicle that comprises picking up the first person at the first location, picking up the second person at the second location, and transporting both persons to the destination.

Abstract: A system for enforcing a set of policies on a first network device is shown. The system includes logic configured for processing on the first network device and a wireless transceiver to communicatively couple with the first network device. The logic, while processing on the first network device, performs operations including: detecting the first network device is moving at a speed above a predetermined threshold and a presence of a wireless transceiver, implementing the set of policies on the first network device, wherein implementation of the set of policies is configured to restrict functionality of the first network device according to a predefined list of functionalities, monitoring first sensory data associated with the first network device, determining that the first sensory data violates a first policy of the set of policies, and responsive to determining that the first sensory data violates the first policy, transmitting an alert.

Abstract: A sealing system for a flow channel includes a mandrel, a swellable element disposed about the mandrel, and a degradable polymeric element disposed on a surface of the swellable element and configured to delay swelling of the swellable element. The degradable polymeric element comprises one or more of the following: polyurethane; cured cyanate ester; an epoxy; polyimide; unsaturated polyester; or nylon.