Abstract: Minimally invasive percutaneous methods, devices, and systems for placing guide wires in bones in a desired position and orientation and for facilitating the treatment of fractures such as but not limited to intertrochanteric fractures or other applications such as osteotomies. The methods, devices, and systems may allow for rapid and reproducible placement of a guide wire in a bone. Each degree of freedom may be controlled independently.

Abstract: A composition includes a reaction product of a mixture of elemental sulfur and at least a first ethylenically unsaturated compound comprising a hydroxyl or carboxyl group.

Abstract: Devices and systems for treating based on light therapy are disclosed. One example device includes an eyewear configured for placement in front of an eye to allow light to reach the eye, and one or more filters having transmission spectra within a range that approximately spans 450 to 570 nm associated with blue or green light. The one or more filters is configured to block light spectra outside of said range and to allow the blue or green light to reach the eye for administering light therapy to a subject exhibiting pain.

Abstract: A biopsy system for harvesting larger volumes of tissue as compared to standard core biopsy needles. The system has a needle with a lumen, an aperture disposed at the distal end of the needle and connected to the lumen, and a cutting mechanism adapted to cut tissue. When the needle is rotated after it is inserted into a target tissue, the cutting mechanism cuts from the tissue and directs the cut tissue portions into the lumen. Multi-bioimpedance measurements are used to guide a needle and direct the application of electricity for cauterizing tissue.

Abstract: A collinear T-cavity VECSEL system generating intracavity Hermite-Gaussian modes at multiple wavelengths, configured to vary each of these wavelengths individually and independently. A mode converter element and/or an astigmatic mode converter is/are aligned intracavity to reversibly convert the Gaussian modes to HG modes to Laguerre-Gaussian modes, the latter forming the system output having any of the wavelengths provided by the spectrum resulting from nonlinear frequency-mixing intracavity (including generation of UV, visible, mid-IR light). The laser system delivers Watt-level output power in tunable high-order transverse mode distribution.

Abstract: A tiled head-mounted display device, comprising: an optical component including a plurality of prisms with free-form surfaces, each prism being a wedge prism comprising a first optical surface, a second optical surface and a third optical surface; and a display component including a plurality of micro-displays, wherein the number of the micro-displays and the number of the prisms with free-form surfaces is identical. The tiled head-mounted display device according to the present invention is compact and light, provides wide field of view and high resolution, especially for the optical tiling head-mounted display device, the exit pupil planes of each display channels are coincident, thus avoiding pupil aberration and keeping exit pupil diameter and eye clearance same as the single ocular. There is no resolution variance throughout the entire field of view, thus preventing extra trapezoid distortion.

Abstract: Methods and systems are described that enable three-dimensional (3D) imaging of objects. One example system includes a light source that produces multiple light beams having specific spectral content and polarization states. The system also includes phase masks that modify the intensity or phase of the light, and projection optics that allow simultaneously projection of at least three fringe patterns onto an object having particular phase, polarization and spectral characteristics. The detection system includes a camera that simultaneously receives light associated with the at the fringe patterns upon reflection from the object, and a processing unit coupled to the camera unit that determines one or both of a phase or a depth information associated with the object. The system and associated methods can efficiency produce 2D images of the object and allow determination of characteristics such as surface profile. The disclosed systems and methods can be effectively implemented with moving objects.

Abstract: The present invention relates generally to a head-mounted projection display, and more particularly, but not exclusively to a polarized head-mounted projection display including a light engine and a compact, high-performance projection lens for use with reflective microdisplays.

Abstract: Systems and methods for computer-implemented patient assistance are disclosed. In certain embodiments, the invention contemplates receiving patient data from plurality of sensors at a patient computer, transmitting patient data to a server, monitoring and analyzing the patient data at the server, and outputting recommended actions from the server to a personnel computer. The recommended actions are calculated based on safety considerations, emotional considerations, and/or a patient's treatment plan.

Abstract: A method for measuring distorted illumination patterns and correcting image artifacts in structured illumination microscopy. The method includes the steps of generating an illumination pattern by interfering multiple beams, modulating a scanning speed or an intensity of a scanning laser, or projecting a mask onto an object; taking multiple exposures of the object with the illumination pattern shifting in phase; and applying Fourier transform to the multiple exposures to produce multiple raw images. Thereafter, the multiple raw images are used to form and then solve a linear equation set to obtain multiple portions of a Fourier space image of the object. A circular 2-D low pass filter and a Fourier Transform are then applied to the portions. A pattern distortion phase map is calculated and then corrected by making a coefficient matrix of the linear equation set varying in phase, which is solved in the spatial domain.

Abstract: The present disclosure is directed to systems and methods of collecting environmental and/or biometric information and/or data using a chronic monitoring apparatus that includes a wearable expandable support structure to wirelessly receive power via a wireless power transfer antenna disposed in, on, or about the wearable expandable support structure. The chronic monitoring apparatus includes power receiver circuitry, data transmission circuitry, sensor circuitry, and control circuitry. The wearable expandable support structure maintains close contact between at least a portion of the sensor circuitry and the wearer of the chronic monitoring apparatus without requiring the use of adhesives or other bonding agents. The chronic monitoring apparatus communicates the collected environmental and/or biometric information to external data collection circuitry.

Abstract: The invention is directed to methods for selecting a treatment option for an activated B cell-like diffuse large B cell lymphoma (ABC DLBCL) subject, a germinal center B cell-like diffuse large B cell lymphoma (GCB DLBCL) subject, a primary mediastinal B cell lymphoma (PMBL) subject, a Burkitt lymphoma (BL) subject, or a mantle cell lymphoma (MCL) subject by analyzing digital gene expression data obtained from the subject, e.g., from a biopsy sample.

Abstract: A three-dimensional imaging system includes at least one light source, a circular or elliptical polarization beamsplitter, a detector arrangement and an image processor. The light source is configured to provide light in a first circular or elliptical polarization state onto an object to be imaged. The circular or elliptical polarization beamsplitter is arranged to spatially separate the light reflected from an object into a first reflected portion in the first polarization state and a second reflected portion in the second polarization state. The first and second circular or elliptical polarization states are orthogonal to one another. The detector arrangement detects at least the first reflected portion of the light and the image processor is configured to generate image information from the detected first reflected portion.

Abstract: Methods, devices and systems provide improved detection, sensing and identification of objects using modulated polarized beams. An example polarization sensitive device includes an illumination source, and a modulator coupled to the illumination source to produce output beams in which polarization states or polarization parameters of the output beams are modulated to produce a plurality of modulated polarized beams. The device further includes a polarization sensitive detector positioned to receive a reflected portion of modulated polarized beams after reflection from an object and to produce information that is indicative of modulation and polarization states of the received beams. The information can be used to enable a determination of a distance between the polarization sensitive device and the object, or a determination of a polarization-specific characteristic of the object.

Abstract: A heat recovery apparatus, system and method of using the same. The heat recovery apparatus includes a particulate inlet, a particulate distributor in fluid communication with the particulate inlet, a cavity in fluid communication with the particulate distributor, a plurality of pipes contained within the cavity and configured for transmission of a heat transfer fluid therethrough, and a particulate outlet in fluid communication with the cavity.

Abstract: A Vertical-Hive Green Box (or V-Hive Green Box) is a modular cultivation system utilized in a modular Vertical Farm or Plant Factory, as well as a warehouse-type or greenhouse-type of vertical farm or plant factory. The V-Hive Green Box includes growing boards, lighting boards, and an irrigation system arranged within a frame structure to maximize the quantity of crops that can be grown within an available volume of space in a modular Vertical Farm unit, warehouse or greenhouse per unit time. The V-Hive Green Box can also include aquaculture boards that can be used for aquaculture of aquatic fish and plants.

Abstract: A method for rendering light field images of a 3D scene in an HMD using an integral-imaging-based light field display. The method includes providing integral imaging (InI) optics including a microdisplay, the InI optics having a central depth plane (CDP) associated therewith; providing an eyepiece in optical communication with the InI optics, the eyepiece and the InI optics together providing InI-HMD optics; sampling the 3D scene using a simulated virtual array of cameras so that each camera captures a respective portion of the 3D scene to create a plurality of elemental images; and displaying the image data on the microdisplay.

Abstract: Various examples are provided related to automated chip design, such as a pareto-optimization framework for automated network-on-chip design. In one example, a method for network-on-chip (NoC) design includes determining network performance for a defined NoC configuration comprising a plurality of n routers interconnected through a plurality of intermediate links; comparing the network performance of the defined NoC configuration to at least one performance objective; and determining, in response to the comparison, a revised NoC configuration based upon iterative optimization of the at least one performance objective through adjustment of link allocation between the plurality of n routers. In another example, a method comprises determining a revised NoC configuration based upon iterative optimization of at least one performance objective through adjustment of a first number of routers to obtain a second number of routers and through adjustment of link allocation between the second number of routers.

Abstract: Compositions and methods for treating a depressive disorder or an anxiety disorder in a subject in need of such treatment are described herein. A therapeutically effective amount of a composition comprising a melanocortin 5 receptor (MC5R) peptide ligand according to the following: in a pharmaceutically acceptable carrier is administered to the subject. Xaa can be Cha or Pro. The MC5R peptide is a selective MC5R antagonist, and administration thereof to the subject can treat the depressive or anxiety disorder with clinical improvement observed in a relatively short time.

Abstract: A low-cost, portable potentiostat capable of performing several different electrochemical experiments (e.g. cyclic voltammetry and anodic stripping voltammetry) was designed. The potentiostat runs on one or more batteries and has a battery life of over two weeks. Further, the potentiostat of the present invention is capable of self-calibrating and has a linear dynamic range spanning several orders of magnitude. It is also capable of saving data onto an onboard data storage card and is able to export the data to a computer for additional analysis. The potentiostat requires no peripheral hardware and is suitable for use by those with even minimal training in electrochemistry.