Patents Assigned to Arkray, Inc.
  • Publication number: 20260242841
    Abstract: The present disclosure relates to a biosensor comprising an enzyme electrode comprising a direct electron transfer type oxidoreductase wherein said enzyme electrode is electrically connected to a gate electrode of a field effect transistor (FET), and a method of measuring a substance using the biosensor.
    Type: Application
    Filed: May 31, 2024
    Publication date: August 20, 2026
    Applicants: THE UNIVERSITY OF NORTH CAROLINA AT CHAPEL HILL, ARKRAY, INC.
    Inventors: Koji SODE, Mika HATADA, David PROBST
  • Publication number: 20260242842
    Abstract: The present disclosure relates to a modified glucose dehydrogenase according to one embodiment of the invention comprises a catalytic subunit, an electron transfer subunit, and a hitchhiker subunit, wherein a carbon nanotube binding peptide (CNTBP) is fused to at least one of the catalytic subunit, the electron transfer subunit, and the hitchhiker subunit; an enzyme electrode comprising a carbon nanotube and the modified glucose dehydrogenase; and a biosensor comprising the enzyme electrode.
    Type: Application
    Filed: May 31, 2024
    Publication date: August 20, 2026
    Applicants: THE UNIVERSITY OF NORTH CAROLINA AT CHAPEL HILL, ARKRAY, INC.
    Inventors: Koji SODE, Junko SHIMAZAKI, Thy LE
  • Publication number: 20260240466
    Abstract: The present disclosure relates to a biosensor comprising: a first coil which is electrically connected to an enzyme electrode and a reference electrode and transmits a signal generated via an enzyme reaction on the enzyme electrode; and a second coil which is placed proximate to the first coil and is connected to a detection device which receives the signal from the first coil, wherein said enzyme electrode comprises a direct electron transfer type oxidoreductase.
    Type: Application
    Filed: May 31, 2024
    Publication date: August 20, 2026
    Applicants: THE UNIVERSITY OF NORTH CAROLINA AT CHAPEL HILL, ARKRAY, INC.
    Inventors: Koji SODE, David PROBST
  • Patent number: 12699081
    Abstract: A method of measuring stable hemoglobin A1c by a hemoglobin separation analysis method based on cation exchange, the method comprising: obtaining an analysis signal from a blood specimen to be measured by the separation analysis method; determining a C value, which is a peak value of a stable hemoglobin A1c peak, and an X value, which is a peak value of a specific peak appearing between the stable hemoglobin A1c peak and a hemoglobin A0 peak, from the analysis signal; and correcting the C value by applying the C value and the X value to a predetermined arithmetic expression to obtain a C? value that is a reduced value from the C value, wherein the arithmetic expression is determined based on a correlation between a C value and an X value obtained from a blood specimen in which a stable hemoglobin A1c value is known by the separation analysis method.
    Type: Grant
    Filed: July 21, 2023
    Date of Patent: August 4, 2026
    Assignee: ARKRAY, Inc.
    Inventors: Naotsugu Onuma, Tomoyuki Matsuda
  • Patent number: 12693288
    Abstract: The present disclosure provides a quality control substance for use in the analysis of erythrocytes, which can be prepared safely with easily available raw materials, which has an excellent preservation stability, and which can be used in the analysis of sediments in a sample. This quality control substance includes artificial particles whose form as observed with a microscope is similar to the form of erythrocytes as observed therewith.
    Type: Grant
    Filed: September 15, 2023
    Date of Patent: July 28, 2026
    Assignee: ARKRAY, Inc.
    Inventors: Kazuko Okumura, Atsushi Nakao, Kazuki Kudo
  • Patent number: 12661042
    Abstract: A protective cover is attached to a measurement device. The measurement device is provided with an insertion aperture for insertion of a test strip onto which a liquid sample is spotted. The protective cover is attached to the measurement device so as to cover a region including surroundings of the insertion aperture. The protective cover is provided with an opening portion into which the test strip is insertable. The opening portion and the insertion aperture are relatively positioned such that, in a state in which the test strip is inserted through the opening portion and inserted into the insertion aperture, an upper face and lower face of the test strip both abut against the protective cover.
    Type: Grant
    Filed: September 20, 2023
    Date of Patent: June 23, 2026
    Assignee: ARKRAY, Inc.
    Inventor: Yuto Kanzaki
  • Patent number: 12650386
    Abstract: A test strip holder includes: a holding member at which at least a portion of a lower side of an inner periphery is a cylindrical surface having a cylindrical shape, and at whose interior a test strip is held, and at which a direction of an imaginary central axis of the cylindrical surface is a horizontal direction or a direction inclined with respect to a vertical direction; an opening portion provided in an outer surface of the holding member; a sorting member rotating at an interior of the holding member around a rotation axis that coincides with the central axis; a pushing piece projecting out from a distal end edge, which is parallel to the central axis, at the sorting member in a direction of rotation of the sorting member; and a sorting piece projecting out from a distal end of the pushing piece toward the cylindrical surface.
    Type: Grant
    Filed: November 8, 2022
    Date of Patent: June 9, 2026
    Assignee: ARKRAY, Inc.
    Inventors: Noriaki Furusato, Yusuke Wada
  • Patent number: 12644860
    Abstract: Provided is a method for analyzing a sample comprising hemoglobin A2 by capillary electrophoresis using an alkaline aqueous solution comprising a cationic polymer, which is the analysis method including the following steps: 1) obtaining an electropherogram of the sample by capillary electrophoresis; 2) specifying a detection time Tx of an X peak; 3) specifying a detection time Ta2 of an HbA2 peak; 4) specifying a detection time Ty of a Y peak; 5) calculating a correction coefficient from a relative relationship of the detection time Tx, Ta2, and Ty; 6) calculating a ratio of an HbA2 peak area to a total peak area or a ratio of a Y peak area to the total peak area in an electropherogram; and 7) correcting the ratio of the HbA2 peak area or the ratio of the Y peak area with the correction coefficient.
    Type: Grant
    Filed: October 12, 2023
    Date of Patent: June 2, 2026
    Assignee: ARKRAY, Inc.
    Inventor: Naotsugu Onuma
  • Patent number: 12613193
    Abstract: A measurement system including: an insertion gate into which a test strip including first and second regions is inserted; a holder accommodating the test strip; a housing including a window facing the test strip; and a smart device including an illuminator illuminating the second region and including a camera imaging the first and second regions, in which the housing includes a mounting part placing the smart device on an outer surface of the housing in a state in which the camera and the illuminator are disposed at positions facing the window, and a measurement light source provided at a position to irradiate the first region, and in a case in which the camera images the first region, the illuminator is turned off while the measurement light source is turned on, and in a case in which the camera images the second region, the illuminator is turned on.
    Type: Grant
    Filed: October 2, 2023
    Date of Patent: April 28, 2026
    Assignee: ARKRAY, Inc.
    Inventors: Fumito Hiramura, Alexander Turner
  • Patent number: 12597097
    Abstract: An information processing device includes an acquisition section that is coupled to a camera that continuously images a sample including a material component and flowing through a flow cell in time series and generates a first image of the sample and a second image in which a portion continuous to the first image in time series overlaps a part of the first image, and acquires the first image and the second image generated by the camera, and an image output section that outputs a composite image obtained by combining the first image and the second image.
    Type: Grant
    Filed: July 24, 2023
    Date of Patent: April 7, 2026
    Assignee: ARKRAY, Inc.
    Inventor: Koji Fujimoto
  • Patent number: 12596117
    Abstract: The present disclosure provides a quality control substance for use in the analysis of erythrocytes, which can be prepared safely with easily available raw materials, which has an excellent preservation stability, and which can be used in the analysis of sediments in a sample. This quality control substance includes artificial particles whose form as observed with a microscope is similar to the form of erythrocytes as observed therewith.
    Type: Grant
    Filed: September 15, 2023
    Date of Patent: April 7, 2026
    Assignee: ARKRAY, Inc.
    Inventors: Kazuko Okumura, Atsushi Nakao, Kazuki Kudo
  • Patent number: 12590920
    Abstract: A biosensor that is capable of performing measurement with a high reproducibility is provided in one aspect. The present disclosure, as one aspect, relates to a biosensor that includes a base material, a conductive part including two or more electrodes provided on a surface of the base material, and a reagent layer provided on at least a part of the conductive part, the reagent layer has a mean thickness of 5 ?m to 10 ?m and a mean thickness difference, calculated based on the following formula, of ?6 ?m to +5 ?m.
    Type: Grant
    Filed: April 20, 2023
    Date of Patent: March 31, 2026
    Assignee: ARKRAY, Inc.
    Inventors: Taro Mashimo, Shinjiro Sekimoto
  • Patent number: 12590946
    Abstract: A test strip container includes: an accommodating member in which a test strip is accommodated; a moving member moving the test strip therein; a door member opening and closing at a side surface of the accommodating member to discharge the test strip out of the accommodating member, and cutting the interior and the exterior of the accommodating member off from each other when closed; a door accommodating portion covering the door member, in which the door member can open and close; and a discharge opening cutting the interior and an exterior of the door accommodating portion off from each other when closed, and is provided at the door accommodating portion so as to open and close to discharge the test strip to the exterior of the door accommodating portion, the discharge opening being able to open when the accommodating member is closed by the door member.
    Type: Grant
    Filed: November 8, 2022
    Date of Patent: March 31, 2026
    Assignee: ARKRAY, Inc.
    Inventors: Noriaki Furusato, Yusuke Wada
  • Patent number: 12568362
    Abstract: A measurement device comprising: a processor; and a memory configured to store a program executed by the processor cause the measurement device to: first advertisement process for establishing a communication between a host device and a communication device by transmitting first advertisement information to the communication terminal, the first advertisement information including first state information indicating a state of the host device and first boding information indicating whether an encryption key used for the communication with the communication terminal is stored or not, in response to disconnection of the communication with the communication terminal, second advertisement process for re-establishing the communication between the host device and the communication terminal by transmitting second advertisement information after the encryption key is shared between the host device and the communication device, the second advertisement information including second boding information indicating that the
    Type: Grant
    Filed: September 22, 2023
    Date of Patent: March 3, 2026
    Assignee: ARKRAY, Inc.
    Inventor: Yutaka Kawabata
  • Patent number: 12533606
    Abstract: A liquid chromatography column comprising: a column tube including a flow path that runs therethrough in an axial direction of the column tube and that is filled with a filler; a filter unit that is mounted at an axial direction end of the column tube to trap the filler inside the flow path; and a cap that includes a through hole communicated with the flow path through the filter unit and that is mounted at the column tube, wherein a gap, which is a space into which the filler overflowing from the flow path can escape when the cap is being attached to the column tube, is formed at an outer side of a contact surface at which the column tube and the filter unit contact each other.
    Type: Grant
    Filed: July 26, 2023
    Date of Patent: January 27, 2026
    Assignee: ARKRAY, Inc.
    Inventor: Takao Minami
  • Patent number: 12535461
    Abstract: Provided are a sample analysis method comprising: separating hemoglobin in a sample from the sample comprising the hemoglobin, in an alkaline solution by capillary electrophoresis, wherein the alkaline solution comprises a cationic polymer having a secondary amino group and a quaternary ammonium base.
    Type: Grant
    Filed: September 11, 2023
    Date of Patent: January 27, 2026
    Assignee: ARKRAY, Inc.
    Inventor: Naotsugu Onuma
  • Patent number: D1122952
    Type: Grant
    Filed: August 22, 2024
    Date of Patent: April 21, 2026
    Assignee: ARKRAY, INC.
    Inventors: Kenya Hara, Kanako Ohashi, Xin Zhong, Yuichi Koseki
  • Patent number: D1122969
    Type: Grant
    Filed: August 22, 2024
    Date of Patent: April 21, 2026
    Assignee: ARKRAY, Inc.
    Inventors: Kenya Hara, Kanako Ohashi, Xin Zhong, Yuichi Koseki
  • Patent number: D1124009
    Type: Grant
    Filed: August 22, 2024
    Date of Patent: April 28, 2026
    Assignee: ARKRAY, INC.
    Inventors: Kenya Hara, Kanako Ohashi, Xin Zhong, Yuichi Koseki
  • Patent number: D1140081
    Type: Grant
    Filed: August 22, 2024
    Date of Patent: August 4, 2026
    Assignee: Arkray, Inc.
    Inventors: Kenya Hara, Chiyong Kim, Kanako Ohashi