Patents Assigned to Arkray, Inc.
  • Patent number: 11199556
    Abstract: A measuring apparatus includes: a measuring unit to measure a signal value corresponding to a concentration of a specified substance of a first sample; an acquiring unit to acquire a reference value pertaining to the specified substance of a second sample; a calculating unit to calculate a concentration value of the specified substance of the first sample, based on the signal value and the reference value; a timing determination unit to determine timing for calibrating the reference value when satisfying at least one of a first condition that an activity status of a user is a predetermined status and a second condition that a variation in the concentration value of the specified substance of the first sample is equal to or smaller than a threshold value; and an input request unit to request the user to input the reference value at the determined timing.
    Type: Grant
    Filed: July 2, 2018
    Date of Patent: December 14, 2021
    Assignee: ARKRAY, Inc.
    Inventor: Takeshi Shimizu
  • Patent number: 11187674
    Abstract: An analytical tool is provided for analysis of a sample by capillary electrophoresis. The analytical tool includes an inlet reservoir into which a sample is introduced, a capillary tube in communication with the inlet reservoir, a filter through which a liquid from the inlet reservoir passes, an enlarged portion undergoing a sudden increase in a cross-sectional area and being in communication with the inlet reservoir and the capillary tube, and a pressure fluctuation reducer for preventing pressure fluctuation at the enlarge portion from affecting a liquid in the capillary tube.
    Type: Grant
    Filed: December 9, 2016
    Date of Patent: November 30, 2021
    Assignee: ARKRAY, Inc.
    Inventors: Takanari Shigemitsu, Naotsugu Onuma
  • Patent number: 11179113
    Abstract: A presentation method for presenting a time period to measure a blood glucose level, the presentation method includes: acquiring first information, the first information including a measurement result in which a glucose level of a user is measured with a time interval using a first measurement device and a measurement time at which the measurement result was acquired; determining, based on a comparison result obtained by comparing the first information with a predetermined threshold of the glucose level and a preset period, the time period for the user to measure the blood glucose level by using a second measurement device; and presenting the time period at a display.
    Type: Grant
    Filed: July 13, 2018
    Date of Patent: November 23, 2021
    Assignee: ARKRAY, Inc.
    Inventors: Keiko Koide, Atsushi Wada, Hideaki Takeda
  • Patent number: 11175283
    Abstract: A method for processing a blood sample is provided that can improve the recovery rate of deformable rare cells that would easily pass through a filter and small rare cells while reducing the filtration area of the filter, and that can recover the rare cells alive.
    Type: Grant
    Filed: September 24, 2014
    Date of Patent: November 16, 2021
    Assignee: ARKRAY, Inc.
    Inventor: Hidenori Takagi
  • Publication number: 20210341410
    Abstract: A manufacturing method for an electrochemical sensor includes an electrode forming step of forming an electrode, made of a porous material with electroconductivity, on an insulating substrate, and a resist forming step of coating a coating region on the electrode by a resist with non-electroconductivity in a solution state, and permeating communicating pores of the porous material with the resist, thereby adjusting a resistance value of the electrode.
    Type: Application
    Filed: April 29, 2021
    Publication date: November 4, 2021
    Applicant: ARKRAY, Inc.
    Inventor: Yoshiharu Sato
  • Patent number: 11162123
    Abstract: A reagent for glutamine synthetase reaction comprising a chelating agent and glutamine synthetase, and a reagent for quantification of ammonia comprising a chelating agent, ATP, glutamic acid, glutamine synthetase, glucose, an oxidized NAD compound, ADP-dependent hexokinase, and glucose-6-phosphate dehydrogenase, are provided.
    Type: Grant
    Filed: August 8, 2018
    Date of Patent: November 2, 2021
    Assignee: ARKRAY, Inc.
    Inventors: Masaki Murakami, Takehiro Funamoto
  • Patent number: 11154657
    Abstract: A method of performing an intravenous drip injection includes a first step, a second step, a third step and a fourth step. A first step includes starting dosing an infusion solution containing a predetermined component by the intravenous drip injection to a dosing recipient. A second step includes extracting a body fluid from the dosing recipient being dosed with the infusion solution. A third step includes measuring a concentration of the predetermined component in the extracted body fluid. A fourth step includes varying the concentration of the predetermined component in the infusion solution, corresponding to the concentration of the predetermined component in the body fluid.
    Type: Grant
    Filed: December 14, 2018
    Date of Patent: October 26, 2021
    Assignee: ARKRAY, Inc.
    Inventors: Kazuo Fukuda, Tsuyoshi Takasu
  • Patent number: 11143595
    Abstract: A plasma spectroscopy analysis method includes a preliminary addition process in which a bonding agent that is an agent other than DMSA is added to the specimen collected from a living body to which meso-2,3-dimercaptosuccinic acid (DMSA) is administered, a concentration process in which the analyte heavy metal ions in the specimen at a vicinity of one of a pair of electrodes by applying a voltage to the pair of electrodes, and a detection process in which plasma is generated by applying a voltage to the pair of electrodes, and luminescence of the analyte metal ions caused by the plasma is detected.
    Type: Grant
    Filed: April 22, 2019
    Date of Patent: October 12, 2021
    Assignee: ARKRAY, Inc.
    Inventors: Tsuyoshi Takasu, Kojiro Honma
  • Publication number: 20210302350
    Abstract: There is provided a biosensor for measuring a measuring target substance in a sample comprising an insulating substrate, an electrode pair provided on the insulating substrate, and a reagent that includes an oxidoreductase and an electron transfer substance and is provided at least on a working electrode of the electrode pair, wherein the working electrode is composed of one or more kinds of nickel alloys selected from the group consisting of a nickel-ruthenium alloy, a nickel-tungsten alloy, and a nickel-vanadium alloy.
    Type: Application
    Filed: March 26, 2021
    Publication date: September 30, 2021
    Applicant: ARKRAY, Inc.
    Inventor: Ayano Nakatani
  • Patent number: 11080512
    Abstract: An information processing device includes a categorizing section configured to extract a material component image identified as a material component from plural images obtained by imaging a sample fluid containing a plurality of types of material components and flowing through a flow cell, and to categorize the extracted material component image by predetermined category, a count derivation section configured to derive a count of the material component per standard visual field, or derive a count per unit liquid volume of the material component contained in the sample fluid, for each of the categories based on the number of material component images categorized by the categorizing section, and a generation section configured to generate an all-component image in which the material component images are arranged according to the counts that have been derived by the count derivation section for each of the categories.
    Type: Grant
    Filed: October 15, 2019
    Date of Patent: August 3, 2021
    Assignee: ARKRAY, Inc.
    Inventors: Koji Fujimoto, Shinya Nakajima, Kenji Nakanishi
  • Patent number: 11073495
    Abstract: A biosensor includes a plurality of electrodes including a working electrode, and a detection layer containing an enzyme for exchanging electrons with the working electrode, a crosslinking agent and an electrically conductive polymer and having a contact area with the working electrode defined by a predetermined area.
    Type: Grant
    Filed: October 14, 2016
    Date of Patent: July 27, 2021
    Assignees: ARKRAY, Inc., Ultizyme International Ltd.
    Inventors: Hisashi Kaneda, Junko Shimazaki
  • Publication number: 20210199674
    Abstract: A flow path for liquid chromatography, which analyzes hemoglobin within a blood sample, is subjected to a surface treatment with a liquid in which is dissolved a surface treating agent having a molecular weight of 200 or less and having two or more chemical structures in each of which a hydroxy group (—OH) and an oxo group (?O) are respectively bonded directly to one phosphor (P) atom.
    Type: Application
    Filed: December 9, 2020
    Publication date: July 1, 2021
    Applicant: ARKRAY, Inc.
    Inventor: Yusuke NAKAYAMA
  • Publication number: 20210182530
    Abstract: A measurement device includes an acquisition unit and a calculation unit. The acquisition unit acquires a first image obtained by image-capturing liquid containing tangible components flowing through a flow path and a second image image-captured simultaneously with the first image and having an image-capturing magnification higher than the first image. The calculation unit sorts, by using clipped images obtained by clipping the tangible components included in the first image and the second image, the tangible components into different types, and that calculates, by using a total number of the tangible components clipped out of the first image and included in a specified category as well as a ratio of a number of each of the tangible components of the different types clipped out of the second image and included in the specified category relative to a total number thereof, the number of the tangible components included in the specified category.
    Type: Application
    Filed: December 16, 2020
    Publication date: June 17, 2021
    Applicant: ARKRAY, Inc.
    Inventor: Yukio WATANABE
  • Publication number: 20210178296
    Abstract: A filter device includes a first filter, a first retaining member that has a hollow shape, the first filter being fitted inside the first retaining member, a second filter that has a smaller pore size than the first filter, a second retaining member that is disposed downstream of the first filter and that has a hollow shape, the second filter being fitted inside the second retaining member, and a spacer that has a hollow shape, that is disposed between the first retaining member and the second retaining member, that maintains a non-contact state between the first filter and the second filter, and that includes a first contact portion contacting the first filter.
    Type: Application
    Filed: December 16, 2020
    Publication date: June 17, 2021
    Applicant: ARKRAY, Inc.
    Inventors: Yusuke NAKAYAMA, Takeshi TAKAGI, Akira KUGA
  • Patent number: 11033900
    Abstract: A method for treating a blood specimen with which capturing rates for both a small rare cell and a rare cell having a high deformability can be improved in the case where rare cells are contained in a blood specimen. The method for isolating or detecting a rare cell includes treating a blood specimen using a filter to isolate or detect a rare cell in the blood specimen.
    Type: Grant
    Filed: March 23, 2016
    Date of Patent: June 15, 2021
    Assignee: ARKRAY, Inc.
    Inventor: Hidenori Takagi
  • Publication number: 20210164888
    Abstract: A determination method includes: using a microchip, including a capillary flow path and a sample reservoir connected to the capillary flow path at an upstream side, to fill the capillary flow path with a first solution for electrophoresis, and supply the sample reservoir with a second solution containing an analyte; applying a voltage between the sample reservoir supplied with the second solution and the inside of the capillary flow path filled with the first solution, to move a component contained in the second solution in the capillary flow path and separate the component in the capillary flow path; optically detecting a value related to a component difference between the first solution and the second solution, other than a value related to the analyte, for the separated component; and determining whether the optical detection is favorable or poor by comparing the optically detected value with a predetermined threshold value.
    Type: Application
    Filed: February 9, 2021
    Publication date: June 3, 2021
    Applicant: ARKRAY, Inc.
    Inventor: Takanari Shigemitsu
  • Publication number: 20210155675
    Abstract: A mutant cytochrome protein originated from a cytochrome protein having three heme-binding domains, which mutant cytochrome protein lacks the first heme-binding domain and the second heme-binding domain as counted from the N-terminus, is provided. The mutant cytochrome protein may lack a region(s) containing the first and second heme-binding domains.
    Type: Application
    Filed: January 26, 2021
    Publication date: May 27, 2021
    Applicants: ARKRAY, Inc., Ultizyme International Ltd.
    Inventors: Koji Sode, Junko Shimazaki, Kazushige Mori, Katsuhiro Kojima
  • Patent number: 10994281
    Abstract: Provided is a method for separating particles, a separation apparatus, and a separation system.
    Type: Grant
    Filed: September 29, 2017
    Date of Patent: May 4, 2021
    Assignee: ARKRAY, Inc.
    Inventor: Masahiro Kozuka
  • Patent number: 10989714
    Abstract: Provided is a method for measuring a glycoprotein using an enzymatic method, and the method includes simplified steps.
    Type: Grant
    Filed: October 1, 2018
    Date of Patent: April 27, 2021
    Assignee: ARKRAY, Inc.
    Inventor: Satoshi Yonehara
  • Patent number: 10948399
    Abstract: A determination method includes: using a microchip, including a capillary flow path and a sample reservoir connected to the capillary flow path at an upstream side, to fill the capillary flow path with a first solution for electrophoresis, and supply the sample reservoir with a second solution containing an analyte; applying a voltage between the sample reservoir supplied with the second solution and the inside of the capillary flow path filled with the first solution, to move a component contained in the second solution in the capillary flow path and separate the component in the capillary flow path; optically detecting a value related to a component difference between the first solution and the second solution, other than a value related to the analyte, for the separated component; and determining whether the optical detection is favorable or poor by comparing the optically detected value with a predetermined threshold value.
    Type: Grant
    Filed: October 17, 2018
    Date of Patent: March 16, 2021
    Assignee: ARKRAY, Inc.
    Inventor: Takanari Shigemitsu