Abstract: A method for converting a measurement value related to saliva includes: acquiring, from a measurement value of a predetermined measurement item using one of an expectorated mouth-rinse liquid and stimulated saliva collected from a subject, a converted value in a case of using another of the expectorated mouth-rinse liquid and the stimulated saliva collected from the subject, based on a correlation obtained in advance between an index measurement value of the predetermined measurement item measured in advance using the expectorated mouth-rinse liquid and an index measurement value of the predetermined measurement item measured in advance using the stimulated saliva, wherein at least one of cariogenic bacteria, occult blood, and leukocytes is selected as the predetermined measurement item.

Abstract: A method for converting a measurement value related to saliva includes: acquiring, from a measurement value of a predetermined measurement item using one of stimulated saliva and resting saliva collected from a subject, a converted value in a case of using another of the stimulated saliva and the resting saliva collected from the subject, based on a correlation obtained in advance between an index measurement value of the predetermined measurement item measured in advance using the stimulated saliva and an index measurement value of the predetermined measurement item measured in advance using the resting saliva, wherein at least one of cariogenic bacteria and ammonia is selected as the predetermined measurement item.

Abstract: Provided is a measurement device that measures a specimen using a sheet-shaped sensor. The measurement device includes: a main body portion in which an insertion port into which the sensor is inserted is formed and a measurement unit that executes measurement related to the specimen is provided; and a movable portion that is movable with respect to the main body portion in a direction along a sheet surface of the sensor in a state of being inserted into the insertion port, and is movable between a storage position and an extension position where an area of the main body portion in planar view is increased more than an area when the movable portion is disposed at the storage position.

Abstract: A method for converting a measurement value related to saliva includes: acquiring, from a measurement value of a predetermined measurement item using one of an expectorated mouth-rinse liquid and resting saliva collected from a subject, a converted value in a case of using the other of the expectorated mouth-rinse liquid and the resting saliva collected from the subject, based on a correlation obtained in advance between an index measurement value of the measurement item measured in advance using the expectorated mouth-rinse liquid and an index measurement value of the measurement item measured in advance using the resting saliva, in which at least one of buffering capacity, acidity, cariogenic bacteria, occult blood, protein, leukocytes, and ammonia is selected as the measurement item.

Abstract: A method for electrochemically measuring an amount of an oxidoreductase using a biosensor which includes a conductive part including two or more electrodes, and a reagent layer that is in contact with the conductive part and includes a substrate of the oxidoreductase and two or more types of mediators. A first mediator transfers, to a second mediator, electrons generated by a reaction between the substrate and the oxidoreductase, and a second mediator transfers, to the electrodes, the electrons transferred from the first mediator. The method includes bringing a sample containing an oxidoreductase into contact with a reagent layer; performing incubation for a predetermined period of time after the contact, to cause the second mediator to accumulate electrons; applying a voltage across the electrodes after the incubation; measuring an electric signal generated by the voltage application; and calculating an amount of the oxidoreductase based on the electric signal.

Abstract: The present disclosure relates to a biosensor comprising an enzyme electrode comprising a direct electron transfer type oxidoreductase wherein said enzyme electrode is electrically connected to a gate electrode of a field effect transistor (FET), and a method of measuring a substance using the biosensor.

Abstract: The present disclosure relates to a modified glucose dehydrogenase according to one embodiment of the invention comprises a catalytic subunit, an electron transfer subunit, and a hitchhiker subunit, wherein a carbon nanotube binding peptide (CNTBP) is fused to at least one of the catalytic subunit, the electron transfer subunit, and the hitchhiker subunit; an enzyme electrode comprising a carbon nanotube and the modified glucose dehydrogenase; and a biosensor comprising the enzyme electrode.

Abstract: The present disclosure relates to a biosensor comprising: a first coil which is electrically connected to an enzyme electrode and a reference electrode and transmits a signal generated via an enzyme reaction on the enzyme electrode; and a second coil which is placed proximate to the first coil and is connected to a detection device which receives the signal from the first coil, wherein said enzyme electrode comprises a direct electron transfer type oxidoreductase.

Abstract: A method of measuring stable hemoglobin A1c by a hemoglobin separation analysis method based on cation exchange, the method comprising: obtaining an analysis signal from a blood specimen to be measured by the separation analysis method; determining a C value, which is a peak value of a stable hemoglobin A1c peak, and an X value, which is a peak value of a specific peak appearing between the stable hemoglobin A1c peak and a hemoglobin A0 peak, from the analysis signal; and correcting the C value by applying the C value and the X value to a predetermined arithmetic expression to obtain a C? value that is a reduced value from the C value, wherein the arithmetic expression is determined based on a correlation between a C value and an X value obtained from a blood specimen in which a stable hemoglobin A1c value is known by the separation analysis method.

Abstract: The present disclosure provides a quality control substance for use in the analysis of erythrocytes, which can be prepared safely with easily available raw materials, which has an excellent preservation stability, and which can be used in the analysis of sediments in a sample. This quality control substance includes artificial particles whose form as observed with a microscope is similar to the form of erythrocytes as observed therewith.

Abstract: A protective cover is attached to a measurement device. The measurement device is provided with an insertion aperture for insertion of a test strip onto which a liquid sample is spotted. The protective cover is attached to the measurement device so as to cover a region including surroundings of the insertion aperture. The protective cover is provided with an opening portion into which the test strip is insertable. The opening portion and the insertion aperture are relatively positioned such that, in a state in which the test strip is inserted through the opening portion and inserted into the insertion aperture, an upper face and lower face of the test strip both abut against the protective cover.

Abstract: A test strip holder includes: a holding member at which at least a portion of a lower side of an inner periphery is a cylindrical surface having a cylindrical shape, and at whose interior a test strip is held, and at which a direction of an imaginary central axis of the cylindrical surface is a horizontal direction or a direction inclined with respect to a vertical direction; an opening portion provided in an outer surface of the holding member; a sorting member rotating at an interior of the holding member around a rotation axis that coincides with the central axis; a pushing piece projecting out from a distal end edge, which is parallel to the central axis, at the sorting member in a direction of rotation of the sorting member; and a sorting piece projecting out from a distal end of the pushing piece toward the cylindrical surface.

Abstract: Provided is a method for analyzing a sample comprising hemoglobin A2 by capillary electrophoresis using an alkaline aqueous solution comprising a cationic polymer, which is the analysis method including the following steps: 1) obtaining an electropherogram of the sample by capillary electrophoresis; 2) specifying a detection time Tx of an X peak; 3) specifying a detection time Ta2 of an HbA2 peak; 4) specifying a detection time Ty of a Y peak; 5) calculating a correction coefficient from a relative relationship of the detection time Tx, Ta2, and Ty; 6) calculating a ratio of an HbA2 peak area to a total peak area or a ratio of a Y peak area to the total peak area in an electropherogram; and 7) correcting the ratio of the HbA2 peak area or the ratio of the Y peak area with the correction coefficient.

Abstract: A measurement system including: an insertion gate into which a test strip including first and second regions is inserted; a holder accommodating the test strip; a housing including a window facing the test strip; and a smart device including an illuminator illuminating the second region and including a camera imaging the first and second regions, in which the housing includes a mounting part placing the smart device on an outer surface of the housing in a state in which the camera and the illuminator are disposed at positions facing the window, and a measurement light source provided at a position to irradiate the first region, and in a case in which the camera images the first region, the illuminator is turned off while the measurement light source is turned on, and in a case in which the camera images the second region, the illuminator is turned on.

Abstract: An information processing device includes an acquisition section that is coupled to a camera that continuously images a sample including a material component and flowing through a flow cell in time series and generates a first image of the sample and a second image in which a portion continuous to the first image in time series overlaps a part of the first image, and acquires the first image and the second image generated by the camera, and an image output section that outputs a composite image obtained by combining the first image and the second image.

Abstract: The present disclosure provides a quality control substance for use in the analysis of erythrocytes, which can be prepared safely with easily available raw materials, which has an excellent preservation stability, and which can be used in the analysis of sediments in a sample. This quality control substance includes artificial particles whose form as observed with a microscope is similar to the form of erythrocytes as observed therewith.