Abstract: The present invention provides a lancing apparatus (A) which includes a lancet (3) which is movable to advance in a first direction from a deeper portion in a housing (2) toward a front end of a cylindrical member (8) and an analysis component (4) disposed in the cylindrical member (8). The analysis component (4) is movable in a second direction opposite to the first direction upon receiving a force in the second direction. When skin (S) bulges, the analysis component (4) moves in the second direction following the bulging of the skin, whereby blood (b) bleeding from the skin (S) is properly introduced to the analysis component (4).

Abstract: The present invention provides a lancet (X1) which includes a case (1) including an internal space (10), and a lancing unit (2) which includes a lancing needle (20) and which is movable within the internal space (10) in an advancing direction from a wait position to an advanced position. The case (1) includes a main body (11) accommodating the lancing unit (2), and a cap (12) which is molded integral with the main body (11) and detachable from the main body (11). The lancing unit (2) includes a cover portion (22) for covering a portion of the lancing needle (20) on the advancing side, for example. The cover portion (22) is detachable together with the cap (12) by exerting a rotational force for rotating the cap (12) and a pulling force for causing relative movement of the cap (12) in the advancing direction for exposing a front end of the lancing needle (20).

Abstract: Substrate specificity for glucose of a glucose dehydrogenase having the amino acid sequence of SEQ ID NO: 13 is improved by substituting another amino acid residue for the amino acid residue at position 472 and/or 475.

Abstract: In an analyzer for analyzing a sample that reacts with a reagent 25, an analyzing tool 10, an infrared sensor 1 and a temperature controlling part 5 are provided. Inside the analyzing tool 10, a reaction cell 24 in which the sample and the reagent 25 react with each other and a heating element 33 that is heated by electrification are provided. The infrared sensor 1 is disposed outside the analyzing tool 10 so as to photoreceive an infrared ray 9 that is emitted from the reaction cell 24, and outputs a signal that is in accordance with an amount of the photoreceived infrared ray 9 to the temperature controlling part 5. The temperature controlling part 5 adjusts a heat value of the heating element 33 based on the signal from the infrared sensor 1.

Abstract: An analyzer in which optical measurement is performed with respect to a sample placed in optically transparent cells of an analysis tool includes a light source unit, a light-receiving unit, a tray on which the tool is placed, and a drive mechanism for driving the tray. The tray includes a holding section that holds the tool in a predetermined position. The drive mechanism reciprocates the tray between a first position where the tool placed on the tray is exposed to the outside of the analyzer and a second position where the tool is accommodated inside the analyzer. The light source unit is disposed so that emitted light is incident on a cell of the tool when the tray is located in the second position. The light-receiving unit is disposed so as to receive light transmitted through the cell when the tray is located in the second position.

Abstract: A monitoring device which measures numerical value information on a subject substance in a body fluid has an electrochemical sensor including a sensor unit for detecting the subject substance which is used in the way of being embedded subcutaneously and generating an electric signal correlating to the numerical value information on the subject substance, and a temperature control unit which adjusts the detected ambient temperature as a temperature ambient to a sensor unit when detecting the subject substance so as to reach a target setting temperature when measuring the subject substance.

Abstract: A precursor of a molecular probe for imaging of pancreatic islets is provided.

Abstract: The present invention relates to an analytical tool (1) comprising a substrate (10), a capillary (13) which is formed on the substrate (10) and into which a sample liquid is to be loaded by movement of the sample liquid in the capillary. The substrate (10) is provided with a liquid movement preventer for preventing the sample liquid loaded into the capillary (13) from moving further. Preferably, the liquid movement preventer includes a stepped portion (18B) projecting from the substrate or a recess provided at the substrate.

Abstract: The present invention relates to a centrifugal separator (5) including a rotor (51) which pivotally supports a container (9) including an upper opening (90B) and which is to be rotated to apply a centrifugal force to the container (9). The rotor (51) includes an evaporation preventer (55A) for preventing separation target liquid contained in the container (9) from evaporating when the rotor (51) is rotated. The evaporation preventer (55A) includes a standing wall (55Ab) which is positioned in front of the upper opening (90B) when the container (9) is pivoted by rotating the rotor (51).

Abstract: Substrate specificity for glucose of a glucose dehydrogenase having the amino acid sequence of SEQ ID NO: 13 is improved by substituting another amino acid residue for the amino acid residue at position 472 and/or 475.

Abstract: The present invention relates to an analysis system including a laser beam oscillator 60 that emits a laser beam for extracting bodily fluid from the skin, and one or more analysis tools 2 that are used for analyzing a specific ingredient in the bodily fluid and that have a through hole 23 through which the laser beam passes. The analysis tool 2 includes plural conductors 20, 21 layered in a state in which they are electrically insulated from each other. The analysis tool 2 further includes an insulation layer 26 interposed between adjacent conductors 20, 21, and insulation layers 27, 28 which covers an outer surface of at least one of two outermost conductors located on the outermost portions among the plural conductors 20, 21.

Abstract: An analyzing device which fits an analyzing instrument 2 thereinto for use and has a disposal mechanism 5 for disposing of the analyzing instrument 2 after completion of analysis, wherein the disposal mechanism 5 inputs a load in a direction different from a disposal direction D1 of the analyzing instrument 2 to dispose of the analyzing instrument 2. In the analyzing device 1 having a connector portion 4 having a terminal to be brought into contact with a terminal of the analyzing instrument 2, the disposal mechanism 4 is arranged below the connector portion 4.

Abstract: The present invention relates to an analyzing instrument (1A) which includes a capillary (31), a fluid feed port (20) for introducing a sample liquid to the capillary (31), and a fluid feed promoter (6) for promoting the introduction of the sample liquid into the feed port (20). The capillary (31) of the analyzer (1A) may be formed on a substrate (2) for example. The fluid feed promoter (6) may include at lease one of a water-absorbing layer having a higher water-absorbing capacity than the substrate (2) and an adhesive layer having a greater adhesion to the skin than the substrate (2).

Abstract: A fluid agitation method is provided, whereby a swirling flow is generated in a trace amount of fluid, thereby agitating the fluid. The fluid agitation method includes introducing the fluid into an agitation chamber (3) including a wall having an uneven mass distribution, and applying oscillation (F) to the wall with frequencies varying in a predetermined frequency range. The uneven mass distribution of the wall is attained, for example, by arranging a plurality of thickened portions (11 to 18) of different thicknesses in a ring.

Abstract: A measuring instrument (A) includes: a storage (1) which has an insertion port (10) for insertion of measuring articles (S) and is capable of storing the measuring articles stacked in a direction of the insertion; and movable members (2A, 2B) for a movement of dispensing a predetermined quantity of the measuring articles (S) out of the storage (1) toward a measuring position (P). With such an arrangement, refilling of the measuring articles (S) to the measuring instrument (A) becomes easy, and the measuring instrument (A) can be always loaded suitably with a quantity of the measuring articles.

Abstract: The present invention relates to an analytical tool including a plurality of flow paths 21 each including a detection cell 26 for detecting a particular component contained in a sample and configured to move the sample by capillarity, and a common path 22 connecting the plurality of flow paths 21 to each other. Each of the flow paths 21 includes a water stopper 29 for preventing the sample from flowing into the common path 22. Preferably, the water stopper 29 suppresses the movement of the sample by differentiating a cross sectional area at a target portion in a direction perpendicular to the sample flow direction from a cross sectional area at a portion near the target portion.

Abstract: The present invention relates to an analytical tool pack (1) including an analytical tool (13) accommodated in one or between a plurality of sealing sheets (12a, 12b). The analytical tool pack (1) includes a stopper portion (146) for holding the analytical tool (13) with the analytical tool (13) caused to project from the sealing sheets (12a, 12b). Preferably, the analytical tool pack (1) further comprises a base film (14) bonded to the sealing sheets (12a, 12b). For example, the stopper portion (146) comprises the bonded portion of the sealing sheets (12a, 12b) and the base film (14). The present invention further relates to an analyzer which uses the analytical tool pack (1). The analyzer comprises an opening mechanism for making a cut (15) in the analytical tool pack (1), and a pushing mechanism for moving the analytical tool (13) relative to the sealing sheets (12a, 12b) to cause the analytical tool (13) to project through the cut (15).

Abstract: The present invention relates to a puncture device 1 for moving a puncture element 21 in a piercing direction N1 and for piercing a target site with the puncture element 21. The puncture device 1 is for moving a second member 42 retaining the puncture element 21 in the direction N1 and in a direction N2 by the rotational motion of a third member 40 as a first member 41 moves in the directions N1 and N2. The puncture device 1 further comprises a piercing depth adjusting mechanism 6 of adjusting a piercing depth of the puncture element 21 to the target site by regulating a rotation angle of the third member 40.