Patents Assigned to Arkray, Inc.
  • Publication number: 20190008426
    Abstract: A measuring apparatus includes: a measuring unit to measure a signal value corresponding to a concentration of a specified substance contained in a first sample; an acquiring unit to acquire a reference value pertaining to the specified substance contained in a second sample; a calculation unit to calculate a concentration value of the specified substance contained in the first sample, based on the signal value and the reference value; a determination unit to determine whether a variation in the concentration value of the specified substance contained in the first sample is equal to or less than a threshold value; and an output unit to output, to a display unit, recommendation information representing recommendation for acquiring the reference value when the variation in the concentration value of the specified substance contained in the first sample is equal to or less than the threshold value.
    Type: Application
    Filed: July 2, 2018
    Publication date: January 10, 2019
    Applicant: ARKRAY, Inc.
    Inventor: Rikiya Shiwaku
  • Patent number: 10175217
    Abstract: A method for recovering a metal, capable of suppressing variations in complex recovery yields among samples is described, wherein the method comprises: forming a complex between a metal in a sample and a chelating agent for metal in a mixture containing the sample and the chelating agent; and filtering the mixture in the presence of an inorganic salt to recover the complex, thereby recovering the metal in the sample.
    Type: Grant
    Filed: February 26, 2015
    Date of Patent: January 8, 2019
    Assignee: ARKRAY, Inc.
    Inventor: Akitsugu Kudo
  • Publication number: 20180372698
    Abstract: A liquid chromatography device includes a column that separates components in a specimen sample, an eluent supply mechanism that alternately supplies two or more types of eluent to the column, and a detection apparatus into which the eluents are introduced after having passed through the column. The detection apparatus detects a specified component of the sample contained in the eluents. The detection apparatus includes a flow cell, a light source, a light-receiving unit, and a scattering plate. The flow cell includes a flow channel through which the eluents flow. The light source is provided outside of the flow cell and irradiates light onto the eluents flowing through the flow channel. The light-receiving unit is provided outside of the flow cell and receives light that has passed through the flow cell. The scattering plate is provided between the light source and the light-receiving unit along a direction of travel of light from the light source.
    Type: Application
    Filed: June 20, 2018
    Publication date: December 27, 2018
    Applicant: ARKRAY, Inc.
    Inventors: Akira Sezaki, Takeshi Takagi
  • Publication number: 20180372612
    Abstract: A flow cell including a flow channel through which a sample fluid and a sheath fluid flow, a sample flow channel that introduces the sample fluid into the flow channel, and at least one sheath flow channel that introduces the sheath fluid into the flow channel. The flow channel includes a flow merging section where the sample flow channel and the sheath flow channel merge, a flattened section that is disposed downstream of the flow merging section, that is formed in line with one wall face of wall faces facing across the flow merging section, and that is shallower in depth than the flow merging section, and a tapered section that connects the flow merging section with the flattened section and that gradually decreases in depth on progression downstream.
    Type: Application
    Filed: June 20, 2018
    Publication date: December 27, 2018
    Applicant: ARKRAY, Inc.
    Inventor: Shigeki MASUDA
  • Publication number: 20180369882
    Abstract: The amount of consumption of a washing solution for a nozzle and the required time for washing are reduced. A nozzle washing apparatus usable for collection of a specimen comprises a washing tank which accommodates a nozzle, a first discharge port which discharges a washing solution supplied into the washing tank from an upper portion of the washing tank, a second discharge port which discharges the washing solution supplied into the washing tank from a position lower than the first discharge port of the washing tank, a detector which detects a range of contact of an outer wall of the nozzle with the specimen, and a controller which discharges the washing solution supplied into the washing tank from one of the first discharge port and the second discharge port on the basis of a detection result obtained by the detector.
    Type: Application
    Filed: June 25, 2018
    Publication date: December 27, 2018
    Applicant: ARKRAY, Inc.
    Inventor: Shinichi OTA
  • Publication number: 20180355395
    Abstract: Provided is a biosensor for measuring a target substance in a sample, wherein the biosensor comprises an electrode pair comprising a working electrode and a counter electrode, and reagents placed at least on the working electrode, wherein the reagents comprise a first oxidoreductase which oxidizes/reduces the target substance, at least one mediator which transfers electrons generated from an oxidation reduction reaction by the first oxidoreductase to the electrode, and a second oxidoreductase which oxidizes/reduces an interfering substance, and wherein the oxidation-reduction potential of the mediator is higher than the oxidation-reduction potential of the first oxidoreductase and lower than the oxidation-reduction potential of the second oxidoreductase.
    Type: Application
    Filed: June 11, 2018
    Publication date: December 13, 2018
    Applicant: ARKRAY, Inc.
    Inventor: Kazuo Fukuda
  • Patent number: 10145765
    Abstract: A method is provided for suppressing, in a color reagent solution which is used to measure a component within a sample and which contains an oxidative color reagent dissolved therein, a background rise that occurs when the color reagent solution is stored. The method includes adjusting a hydrogen ion exponent (pH) of the color reagent solution so as to be strongly acidic. The hydrogen ion exponent is preferably adjusted to 2.9 or below or to 2.1 or below. The color reagent solution is preferably used to measure the degree of oxidative stress. The oxidative color reagent is preferably a phenylenediamine derivative.
    Type: Grant
    Filed: March 23, 2015
    Date of Patent: December 4, 2018
    Assignee: ARKRAY, Inc.
    Inventors: Kazuhiro Omiya, Toshihiro Imai
  • Patent number: 10126631
    Abstract: Excitation light of two wavelengths is incident to an optical crystal from a first face side, and a terahertz wave THzb is generated from a second face, and the excitation light that has passed through the optical crystal is reflected, made incident to the optical crystal from the second face side, and a terahertz wave THza is generated from the first face. Terahertz waves with similar characteristics to each other are thereby generated reliably in plural directions.
    Type: Grant
    Filed: January 3, 2014
    Date of Patent: November 13, 2018
    Assignee: ARKRAY, Inc.
    Inventors: Hirohisa Uchida, Naoto Shichi
  • Patent number: 10113942
    Abstract: A method is provided for suppressing, in a color reagent solution which is used to measure a component within a sample and which contains an oxidative color reagent dissolved therein, a background rise that occurs when the color reagent solution is stored. The method includes adjusting a hydrogen ion exponent (pH) of the color reagent solution so as to be strongly acidic. The hydrogen ion exponent is preferably adjusted to 2.9 or below or to 2.1 or below. The color reagent solution is preferably used to measure the degree of oxidative stress. The oxidative color reagent is preferably a phenylenediamine derivative.
    Type: Grant
    Filed: March 23, 2015
    Date of Patent: October 30, 2018
    Assignee: ARKRAY, Inc.
    Inventors: Kazuhiro Omiya, Toshihiro Imai
  • Patent number: 10107793
    Abstract: A method for recovering a metal that uses a reduced amount of a chelating agent is described, where the method includes a complex forming step of forming, in a mixture, a complex between a metal in a sample and a chelating agent; a complex depositing step of depositing the complex in the mixture; and a metal recovering step of recovering the deposited complex from the mixture, thereby recovering the metal in the sample.
    Type: Grant
    Filed: February 26, 2015
    Date of Patent: October 23, 2018
    Assignee: ARKRAY, Inc.
    Inventors: Hirofumi Yamada, Akitsugu Kudo
  • Patent number: 10101275
    Abstract: The present invention provides a plasma spectrochemical analysis method that can be carried out easily and achieves high analytical sensitivity, and includes: a step of concentrating an analyte in a sample in the vicinity of at least one of a pair of electrodes by applying a voltage to the pair of electrodes in the presence of the sample; and a step of generating plasma by applying a voltage to the pair of electrodes and detecting light emitted from the analyte excited by the plasma.
    Type: Grant
    Filed: January 13, 2016
    Date of Patent: October 16, 2018
    Assignee: ARKRAY, Inc.
    Inventors: Yasunori Shiraki, Hitoshi Okai
  • Publication number: 20180230613
    Abstract: An electrolysis device including a cell that contains a solution and a pair of electrodes installed in the cell. One electrode of the pair of electrodes is a carbon electrode, and a liquid-contacting portion of the carbon electrode that makes contact with the solution in the cell is configured by only a three-dimensional curved face.
    Type: Application
    Filed: February 14, 2018
    Publication date: August 16, 2018
    Applicant: ARKRAY, Inc.
    Inventor: Tokuo Kasai
  • Publication number: 20180230608
    Abstract: An electrolysis device comprising a cell containing a solution, a pair of electrodes installed in the cell, and a voltage application device connected to the pair of electrodes. One electrode of the pair of electrodes is a small electrode, and another electrode of the pair of electroeds is a large electrode. An area of a liquid-contacting portion of the small electrode with the solution is smaller than an area of a liquid-contacting portion of the large electrode with the solution. In a state in which the solution is contained in the cell, only the solution is present between the liquid-contacting portion of the small electrode and a liquid surface of the solution vertically above the liquid-contacting portion of the small electrode.
    Type: Application
    Filed: February 14, 2018
    Publication date: August 16, 2018
    Applicant: ARKRAY, Inc.
    Inventor: Tokuo Kasai
  • Patent number: 10035149
    Abstract: A mixing container includes a first container that stores two or more reagents and a second container for mixing two or more reagents. The first container includes reagent storage chambers that are respectively provided for the two or more reagents and have openings formed at portions thereof, and a sealing member that seals the respective openings of the reagent storage chambers. The second container includes an opening portion formed such that the first container can be connected thereto, and protruding portions disposed so as to pierce the sealing member when the first container is connected to the opening portion.
    Type: Grant
    Filed: December 14, 2015
    Date of Patent: July 31, 2018
    Assignees: ARKRAY, Inc., BODITECH MED INC.
    Inventors: Fumito Hiramura, Hironori Hasegawa, Park Ki Tae, Kim Cheol Min
  • Patent number: 10029022
    Abstract: Provided is a radioactive labeled compound capable of detecting a secondary mutation of an epidermal growth factor receptor, where the compound is represented by Formula (1) or a pharmaceutically acceptable salt thereof, where Y, L1, R1 and R2 are as defined.
    Type: Grant
    Filed: April 28, 2016
    Date of Patent: July 24, 2018
    Assignees: Kyoto University, ARKRAY, Inc.
    Inventors: Hideo Saji, Hiroyuki Kimura, Hirokazu Matsuda, Shuichi Nakanishi
  • Publication number: 20180202915
    Abstract: A flow cell has: a flow path in which a specimen fluid and a sheath fluid flow; a specimen flow path that introduces the specimen fluid into the flow path; a first sheath flow path and a second sheath flow path that introduce the sheath fluid into the flow path; and a merging portion at which the specimen flow path, the first sheath flow path and the second sheath flow path merge together. The specimen flow path is provided on a central flow line of the flow path. At the merging portion, the first sheath flow path and the second sheath flow path face directions intersecting the central flow line of the flow path, and are disposed at positions that are offset in a depth direction of the flow path.
    Type: Application
    Filed: December 28, 2017
    Publication date: July 19, 2018
    Applicant: ARKRAY, Inc.
    Inventor: Shigeki MASUDA
  • Patent number: 10018589
    Abstract: A method for analyzing a sample using capillary electrophoresis is provided. By the method, following steps are performed. First, an original sample and an anionic group-containing compound are fixed to form a mixed sample, where the original sample contains an analysis component to be analyzed and a sub component other than the analysis component. Then, an aggregate of the sub component and the anionic group-containing compound is removed from the mixed sample. Then, electrophoresis is performed in a capillary tube with respect to a complex in which the analysis component and the anionic group-containing compound are bound to each other, while the mixed sample is continuously supplied.
    Type: Grant
    Filed: September 4, 2015
    Date of Patent: July 10, 2018
    Assignee: ARKRAY, Inc.
    Inventor: Naotsugu Onuma
  • Publication number: 20180164247
    Abstract: An analytical tool for use in analysis of a sample is provided. The analytical tool includes a first unit and a second unit. The first unit has an analysis portion where analysis is performed. The second unit, configured to be coupled with the first unit, has a liquid reservoir for confining a particular liquid used for the analysis of the sample. When the first unit and the second unit are coupled, a fluid passage for conducting the particular liquid from the liquid reservoir into the first unit is formed by only a part of the first unit, or only a part of the second unit, or a combination of respective parts of the first unit and the second unit.
    Type: Application
    Filed: February 8, 2018
    Publication date: June 14, 2018
    Applicant: ARKRAY, Inc.
    Inventor: Naotsugu Onuma
  • Patent number: 9995709
    Abstract: Provided is a substrate modification method that enables improvement of reproducibility in measurement with use of capillary electrophoresis. The substrate modification method includes immobilizing, to a substrate surface, at least two types of modification groups selected from three types of modification groups that are a type of a modification group having one functional group, a type of a modification group having two to nine functional groups, and a type of a modification group having ten or more functional groups.
    Type: Grant
    Filed: October 26, 2012
    Date of Patent: June 12, 2018
    Assignee: ARKRAY, Inc.
    Inventor: Yusuke Nakayama
  • Patent number: D828574
    Type: Grant
    Filed: January 28, 2016
    Date of Patent: September 11, 2018
    Assignee: ARKRAY, INC.
    Inventors: Takaaki Fujiwara, Kazuyoshi Kamekawa