Patents Assigned to Arkray, Inc.
  • Patent number: 10337985
    Abstract: Provided is a measurement system for performing qualitative measurement and quantitative measurement of a measurement item of a biological sample, the measurement system including a quantitative sample adjustment criterion storage section that stores a quantitative sample adjustment criterion corresponding to a qualitative measurement result in the qualitative measurement, a determination section that determines a proper quantitative sample adjustment condition by referring to the quantitative sample adjustment criterion to determine necessity to change the quantitative sample adjustment condition based on the qualitative measurement result, and an adjustment section that adjusts the biological sample based on the quantitative sample adjustment condition determined by the determination section.
    Type: Grant
    Filed: April 11, 2016
    Date of Patent: July 2, 2019
    Assignee: ARKRAY, Inc.
    Inventor: Shinya Nakajima
  • Publication number: 20190184100
    Abstract: A method of performing an intravenous drip injection includes a first step, a second step, a third step and a fourth step. A first step includes starting dosing an infusion solution containing a predetermined component by the intravenous drip injection to a dosing recipient. A second step includes extracting a body fluid from the dosing recipient being dosed with the infusion solution. A third step includes measuring a concentration of the predetermined component in the extracted body fluid. A fourth step includes varying the concentration of the predetermined component in the infusion solution, corresponding to the concentration of the predetermined component in the body fluid.
    Type: Application
    Filed: December 14, 2018
    Publication date: June 20, 2019
    Applicant: ARKRAY, Inc.
    Inventors: Kazuo Fukuda, Tsuyoshi Takasu
  • Patent number: 10317403
    Abstract: The present invention provides an immunoassay analyzer capable of discriminating between normal coloring due to a specific immunoreaction and abnormal coloring due to a cause other than the specific immunoreaction in a measurement region of a sample analysis tool. An immunoassay analyzer 1 of the present invention includes an optical detection unit 4 and a determination unit 5. The optical detection unit 4 includes an optical signal measurement unit for measuring an optical signal at each of two or more different wavelengths including a main wavelength for detecting color change due to the specific immunoreaction and a sub-wavelength(s) other than the main wavelength. The determination unit 5 includes a discrimination unit for comparing the respective optical signals at the two or more different wavelengths and discriminating between the color change due to the specific immunoreaction and color change due to a cause other than the specific immunoreaction based on a comparison criterion determined previously.
    Type: Grant
    Filed: February 1, 2013
    Date of Patent: June 11, 2019
    Assignee: ARKRAY, Inc.
    Inventor: Kyouichi Ohshiro
  • Patent number: 10309888
    Abstract: Provided is a method for measuring the concentration of a substance in a blood sample, the method comprising the steps of: supplying the blood sample to a biosensor comprising a hematocrit electrode for measuring a hematocrit value on the surface of which electrode an electrically conductive polymer is coated by physical adsorption in the absence of a crosslinking agent; and calculating the concentration of the substance from the measured value of a first current resulting from application of a first voltage; and correcting the concentration of the substance with the value of a second current resulting from application of a second voltage or the hematocrit value calculated from the value of the second current.
    Type: Grant
    Filed: April 5, 2016
    Date of Patent: June 4, 2019
    Assignee: ARKRAY, Inc.
    Inventors: Megumi Saeda, Hisashi Kaneda
  • Publication number: 20190153505
    Abstract: The disclosure provides for a method for determining the stage of a periodontal disease by using as an index the amount of occult blood, and the number of white blood cells or a total protein concentration in the examination object obtained from the oral cavity.
    Type: Application
    Filed: March 31, 2017
    Publication date: May 23, 2019
    Applicant: ARKRAY, Inc.
    Inventors: Riichi Maki, Haruhiko Fujikawa, Isao Fukuta
  • Patent number: 10295495
    Abstract: There is provided a sensor testing method including: applying at least one of a first voltage that obtains a response caused by a substance and a second voltage that either obtains no response or substantially no response caused by the substance across a first electrode and a second electrode of a sensor; measuring current flowing between the first electrode and the second electrode; and determining whether or not there is a defect present in the sensor based on a quantity related to an amount of change per specific period of time of a current measured when the first voltage and/or the second voltage have been applied.
    Type: Grant
    Filed: February 18, 2016
    Date of Patent: May 21, 2019
    Assignee: ARKRAY, Inc.
    Inventor: Shinjiro Sekimoto
  • Patent number: 10295471
    Abstract: A plasma spectroscopic analysis method includes a concentration process of concentrating a target in a sample, in the vicinity of one of a pair of electrodes in the presence of the sample; a plasma generation process of generating plasma in the sample by applying a voltage to the pair of electrodes; and a detection process of detecting emission of the target generated by the plasma, wherein the plasma generation process is performed in the presence of a defoaming agent.
    Type: Grant
    Filed: October 4, 2017
    Date of Patent: May 21, 2019
    Assignee: ARKRAY, Inc.
    Inventor: Tokuo Kasai
  • Publication number: 20190137502
    Abstract: Provided is a method for measuring a glycoprotein using an enzymatic method, and the method includes simplified steps.
    Type: Application
    Filed: October 1, 2018
    Publication date: May 9, 2019
    Applicant: ARKRAY, Inc.
    Inventor: Satoshi Yonehara
  • Publication number: 20190137509
    Abstract: Provided is a reagent that is suitable for measurement of a glycoprotein and contains a compound capable of stabilizing a leuco dye.
    Type: Application
    Filed: October 1, 2018
    Publication date: May 9, 2019
    Applicant: ARKRAY, Inc.
    Inventors: Takuho Kasai, Satoshi Yonehara
  • Patent number: 10278625
    Abstract: Provided is a blood measuring apparatus including: a spectroscope; an optical system configured to irradiate a living body with excitation light from a light source, and to guide, to the spectroscope, Raman scattered light from the living body; a control unit configured to adjust an irradiation position at which the living body is irradiated with the excitation light by the optical system; and a detector configured to detect a spectrum of the Raman scattered light using light of each wavelength dispersed by the spectroscope. A plurality of the spectra detected by the detector are integrated, and numerical value information regarding a substance included in blood of the living body is measured based on an integration result, and the control unit adjusts the irradiation position such that the plurality of spectra are detected at changed positions.
    Type: Grant
    Filed: October 7, 2016
    Date of Patent: May 7, 2019
    Assignee: ARKRAY, Inc.
    Inventors: Takeshi Shimizu, Yasuhide Kusaka
  • Publication number: 20190128796
    Abstract: An analysis device includes a guide-in section, a placement section, an illumination member, a pressing member, and a measurement member. The guide-in section is configured to guide a rectangular block shaped analysis kit containing a sample. The analysis kit is placed on the placement section in the guide-in section. The illumination member is inserted into an insertion hole formed in the analysis kit, contacts a bottom of the insertion hole, and illuminates light onto the sample. The pressing member is configured by a separate body to the illumination member and presses the analysis kit such that the analysis kit placed on the placement section is sandwiched between the pressing member and the placement section and retained at a predetermined position. The measurement section measures a component present in the sample using light illuminated from the illumination member onto the sample in the analysis kit placed on the placement section.
    Type: Application
    Filed: October 26, 2018
    Publication date: May 2, 2019
    Applicant: ARKRAY, Inc.
    Inventors: Akihiro YAMAMOTO, Naoto SHICHI
  • Publication number: 20190128915
    Abstract: An analysis device that includes a placement section, a pressing member, and a measurement member, has an analysis kit including a chip provided with a capillary through which a sample flows and a cartridge superimposed on the chip, and in which a liquid reservoir placed therein to enable a component present in sample can be measured in a state in which the chip and the cartridge have been fitted together. The analysis kit is placed on the placement section. The pressing member presses the analysis kit in a direction in which the cartridge is superimposed on the chip to sandwich the analysis kit between the pressing member and the placement section, and to fit the chip and the cartridge together. The measurement member that measures the component present in the sample in the analysis kit in which the chip and the cartridge have been fitted together.
    Type: Application
    Filed: October 26, 2018
    Publication date: May 2, 2019
    Applicant: ARKRAY, Inc.
    Inventors: Akihiro YAMAMOTO, Naotsugu ONUMA
  • Publication number: 20190128254
    Abstract: A method of driving a pump is used in a pressure-applying apparatus, the apparatus including a flow passage, a pump configured to impart pressure into the flow passage, an opening and closing valve configured to open and close the flow passage, a pressure detector configured to detect pressure in the flow passage, and an atmospheric air open valve configured to open an interior of the flow passage to atmospheric air. The method includes driving the pump after closing the opening and closing valve and opening the atmospheric air open valve, and evaluating a state of the pump, based on one of: the pressure detected by the pressure detector at a time at which a predetermined time period has elapsed after closing the atmospheric air open valve, and a time from closing of the atmospheric air open valve until detection of a predetermined pressure by the pressure detector.
    Type: Application
    Filed: October 26, 2018
    Publication date: May 2, 2019
    Applicant: ARKRAY, Inc.
    Inventors: Naoto SHICHI, Daisuke MATSUMOTO, Takanari SHIGEMITSU
  • Publication number: 20190128914
    Abstract: An analysis device employs an analysis kit including a chip provided with a capillary through which a sample flows and a cartridge superimposed on the chip and provided with a liquid reservoir. The analysis device includes a guide-in section into which the analysis kit is guided, a placement section on which the analysis kit placed so as to be supported, a pusher member that pushes the analysis kit from one side face of the analysis kit, contact members that oppose another side face on an opposite side in the horizontal direction to the one side face of the analysis kit placed on the placement section, and contact the other side face of the analysis kit being pushed in by the pusher member so as to position the analysis kit in the horizontal direction, and a measurement member that measures a component present in the sample in the analysis kit.
    Type: Application
    Filed: October 26, 2018
    Publication date: May 2, 2019
    Applicant: ARKRAY, Inc.
    Inventors: Akihiro YAMAMOTO, Shigeru KITAMURA, Naoto SHICHI
  • Publication number: 20190128912
    Abstract: An analysis device includes a guide-in section, a piercing member, an airtight member, a gas introduction member, and a measurement member. The guide-in section is configured to guide a rectangular block shaped analysis kit containing a sample. The piercing member pierces a sealing film at an upper face of a liquid reservoir formed in the analysis kit. The airtight member forms an airtight space against the analysis kit at the periphery of a location pierced by the piercing member. The gas introduction member introduces gas into the airtight space. The measurement member measures a component present in the sample in the analysis kit guided into the guide-in section.
    Type: Application
    Filed: October 26, 2018
    Publication date: May 2, 2019
    Applicant: ARKRAY, Inc.
    Inventors: Akihiro Yamamoto, Daisuke Matsumoto, Masao Kawano
  • Publication number: 20190120749
    Abstract: A determination method includes: using a microchip, including a capillary flow path and a sample reservoir connected to the capillary flow path at an upstream side, to fill the capillary flow path with a first solution for electrophoresis, and supply the sample reservoir with a second solution containing an analyte; applying a voltage between the sample reservoir supplied with the second solution and the inside of the capillary flow path filled with the first solution, to move a component contained in the second solution in the capillary flow path and separate the component in the capillary flow path; optically detecting a value related to a component difference between the first solution and the second solution, other than a value related to the analyte, for the separated component; and determining whether the optical detection is favorable or poor by comparing the optically detected value with a predetermined threshold value.
    Type: Application
    Filed: October 17, 2018
    Publication date: April 25, 2019
    Applicant: ARKRAY, Inc.
    Inventor: Takanari Shigemitsu
  • Publication number: 20190117154
    Abstract: A measuring apparatus includes: a measurement unit configured to measure a concentration value of a specified substance contained in a sample; an acquiring unit configured to acquire information about a user's activity status; a calculation unit configured to calculate a concentration value of the specified substance within a second period ranging from present time to second predetermined time after the present time, based on a concentration value of the specified substance within a first period ranging from first predetermined time before the present time to the present time and the information about the user's activity status within the first period; and an informing unit configured to inform a user of the information about the concentration value of the specified substance when the concentration value of the specified substance within the second period does not fall within a range of a predetermined concentration value.
    Type: Application
    Filed: October 19, 2018
    Publication date: April 25, 2019
    Applicant: ARKRAY, Inc.
    Inventors: Takeshi Shimizu, Yasuhide Kusaka
  • Publication number: 20190120790
    Abstract: The present analysis method for analyzing a sample uses capillary electrophoresis by applying a voltage to a sample solution introduced to a micro flow path, performing separation analysis for a component contained in the sample solution, and measuring an optical measurement value at a measurement section of the micro flow path corresponding to an elapsed time after a start of measurement.
    Type: Application
    Filed: October 17, 2018
    Publication date: April 25, 2019
    Applicant: ARKRAY, Inc.
    Inventors: Masao Kawano, Naotsugu Onuma
  • Publication number: 20190120861
    Abstract: An ascorbic acid responsive electrode comprising an electrode, and a detection layer comprising a non-catalytic electron acceptor that receives an electron from ascorbic acid, an amino acid, and a saccharide and/or a soluble protein; wherein in the detection layer the electron acceptor is reduced by the ascorbic acid, and the reduced electron acceptor is oxidized at the electrode.
    Type: Application
    Filed: October 23, 2018
    Publication date: April 25, 2019
    Applicant: ARKRAY, Inc.
    Inventor: Kazuo Fukuda
  • Publication number: 20190101742
    Abstract: A plurality of images of a sample are simultaneously captured at different focal lengths by a plurality of cameras. An analysis apparatus includes: a branch section configured to cause light passing through the sample containing a material component to branch off into a plurality of optical paths; a plurality of imaging devices for simultaneously capturing images of the sample in a flow path at different focal points by using the light caused to branch off into the plurality of optical paths; and a controller configured to process the captured images.
    Type: Application
    Filed: September 27, 2018
    Publication date: April 4, 2019
    Applicant: ARKRAY, Inc.
    Inventors: Shinya NAKAJIMA, Shigeki MASUDA, Kenji NAKANISHI, Yukio WATANABE