Patents Assigned to Arkray
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Publication number: 20240377332Abstract: A measurement method including: photographing a pre-measurement image in a state in which a test piece is irradiated with measurement light in a measurement region of the test piece before the sample is introduced; measuring luminescence intensity for each of plural measurement sites in the photographed pre-measurement image; specifying an arithmetic value that equalizes the luminescence intensity of each measurement site in the pre-measurement image for each measurement site; photographing a measurement image in a state in which the measurement region of the test piece after the sample is introduced is irradiated with the measurement light; measuring luminescence intensity for each measurement site corresponding to each measurement site of the pre-measurement image in the photographed measurement image; and correcting the luminescence intensity of each measurement site in the measurement image with the arithmetic value of the measurement site.Type: ApplicationFiled: May 8, 2024Publication date: November 14, 2024Applicant: ARKRAY, Inc.Inventors: Fumito HIRAMURA, Toru ODAGAKI
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Patent number: 12135305Abstract: There is provided a biosensor for measuring a measuring target substance in a sample comprising an insulating substrate, an electrode pair provided on the insulating substrate, and a reagent that includes an oxidoreductase and an electron transfer substance and is provided at least on a working electrode of the electrode pair, wherein the working electrode is composed of one or more kinds of nickel alloys selected from the group consisting of a nickel-ruthenium alloy, a nickel-tungsten alloy, and a nickel-vanadium alloy.Type: GrantFiled: March 26, 2021Date of Patent: November 5, 2024Assignee: ARKRAY, INC.Inventor: Ayano Nakatani
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Publication number: 20240353379Abstract: A method of treating a measurement flow channel, the method comprising performing a conditioning treatment of causing a conditioning liquid, in which albumin, casein, or skim milk is dissolved, to flow through a measurement flow channel of a liquid chromatography device for analyzing hemoglobin in a specimen before analyzing the hemoglobin.Type: ApplicationFiled: April 5, 2024Publication date: October 24, 2024Applicant: ARKRAY, Inc.Inventor: Kazuki ISHIKAWA
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Patent number: 12117451Abstract: A dry test piece for albumin measurement is based on the improved BCP method as a principle, and enables the measurement of albumin at a high sensitivity. The test piece includes a support; and a reagent holding layer provided on the support and on which a sample is spotted. The reagent holding layer contains a protein denaturation agent (component A), an SH reagent (component B), bromcresol purple (component C), and a nonionic surfactant (component D). In the reagent holding layer, a weight ratio (D/C) of the component D to the component C is 0.3 to 13, a content of the component C relative to an amount of the spotted sample is 0.4 ?g/?L to 5.4 ?g/?L, a content of the component D relative to the amount of the spotted sample is 25 ?g/?L or less.Type: GrantFiled: November 26, 2021Date of Patent: October 15, 2024Assignee: ARKRAY, Inc.Inventors: Keigo Uda, Miki Inatome
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Publication number: 20240307478Abstract: In one aspect, the present disclosure aims to provide a novel phosphodiesterase 5 inhibitor that uses plants as raw materials. One aspect of the present disclosure relates to a phosphodiesterase 5 inhibitor containing extracts of plants. Another aspect of the present disclosure relates to a food composition, beverage composition, health food, cosmetic, dietary supplement, quasi-drug, or pharmaceutical composition.Type: ApplicationFiled: March 13, 2024Publication date: September 19, 2024Applicant: ARKRAY, Inc.Inventors: Naoki MATSUO, Kiyofumi TAKAYAMA, Eiji YUASA, Junichi TAKIMURA
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Publication number: 20240252953Abstract: In a flow path member joining structure for enabling a liquid to flow by attaching, to a first member having a first flow path, a second member having a second flow path and aligning the first flow path and the second flow path with each other, the first flow path is opened to a first end face of the first member, the second flow path is opened to a second end face of the second member, and the second end face is formed as an inclined surface inclined from an opening of the second flow path toward a periphery.Type: ApplicationFiled: January 29, 2024Publication date: August 1, 2024Applicant: ARKRAY, Inc.Inventor: Takao MINAMI
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Publication number: 20240255080Abstract: In a flow path member joining structure for enabling a liquid to flow by attaching, to a first member having a first flow path, a second member having a second flow path and aligning the first flow path and the second flow path with each other, the first flow path is open toward a first end face of the first member, and an enlarged diameter portion whose inner diameter gradually increases toward the first end face is formed at an end of the first flow path, and the second flow path is open toward a second end face of the second member.Type: ApplicationFiled: January 29, 2024Publication date: August 1, 2024Applicant: ARKRAY, Inc.Inventor: Takao MINAMI
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Publication number: 20240230548Abstract: A measurement system including: an insertion gate into which a test strip including first and second regions is inserted; a holder accommodating the test strip; a housing including a window facing the test strip; and a smart device including an illuminator illuminating the second region and including a camera imaging the first and second regions, in which the housing includes a mounting part placing the smart device on an outer surface of the housing in a state in which the camera and the illuminator are disposed at positions facing the window, and a measurement light source provided at a position to irradiate the first region, and in a case in which the camera images the first region, the illuminator is turned off while the measurement light source is turned on, and in a case in which the camera images the second region, the illuminator is turned on.Type: ApplicationFiled: October 2, 2023Publication date: July 11, 2024Applicant: ARKRAY, Inc.Inventors: Fumito HIRAMURA, Alexander TURNER
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Publication number: 20240201206Abstract: Provided is a method for estimating a hemoglobin A1c level including acquiring in advance a correlation between a hemoglobin A1c level which is based on the ratio of the peak value of a hemoglobin A1c peak to the total of the peak values related to hemoglobin A and a glycated mutant hemoglobin level which is based on the ratio of the peak value of a glycated mutant hemoglobin peak to the total of the peak values containing mutant hemoglobin and the peak value of the glycated mutant hemoglobin peak containing glycated mutant hemoglobin formed by glycating the mutant hemoglobin, from a chromatogram of a blood specimen that contains the hemoglobin A and the mutant hemoglobin, deriving a glycated mutant hemoglobin level from a chromatogram of a blood specimen, and estimating a hemoglobin A1c level based on the derived glycated mutant hemoglobin level and the correlation.Type: ApplicationFiled: December 14, 2023Publication date: June 20, 2024Applicant: ARKRAY, Inc.Inventor: Kazuki ISHIKAWA
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Publication number: 20240159705Abstract: Provided is a sample analysis method, the sample analysis method including separating a protein from a sample containing the protein, in an alkaline solution by capillary electrophoresis, in which separation of the protein is performed in a presence of a cationic low-molecular compound having two or more primary amino groups, and the alkaline solution containing a cationic polymer.Type: ApplicationFiled: October 24, 2023Publication date: May 16, 2024Applicant: ARKRAY, Inc.Inventor: Misaki OGA
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Publication number: 20240159769Abstract: Provided is a sample analysis method, including separating albumin and ?-globulin from a sample containing albumin and ?-globulin, in an alkaline solution by capillary electrophoresis, in which the sample contains a non-surfactant-type sulfobetaine, and the alkaline solution contains a cationic polymer.Type: ApplicationFiled: October 24, 2023Publication date: May 16, 2024Applicant: ARKRAY, Inc.Inventors: Misaki OGA, Atsushi SUGIMOTO
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Publication number: 20240139729Abstract: A protective cover is for use with a measurement device. The measurement device is provided with an insertion aperture for insertion of a test strip onto which a liquid sample is spotted. The protective cover is inflected such that a rear face side thereof is recessed to match the shape of an end portion of the measurement device at which the insertion aperture is disposed. The protective cover is provided with an opening portion at which the test strip is insertable. A first drawing portion is provided at a rear face side lower edge of the opening portion. The first drawing portion draws the liquid sample by capillary force.Type: ApplicationFiled: September 20, 2023Publication date: May 2, 2024Applicant: ARKRAY, Inc.Inventor: Yuto KANZAKI
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Publication number: 20240142434Abstract: Provided are a sample analysis method including separating albumin and ?-globulin from a sample containing albumin and ?-globulin, in an alkaline solution by capillary electrophoresis, in which the alkaline solution contains a cationic polymer, and the like.Type: ApplicationFiled: October 24, 2023Publication date: May 2, 2024Applicant: ARKRAY, Inc.Inventors: Misaki OGA, Naotsugu ONUMA
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Publication number: 20240138733Abstract: A protective cover is attached to a measurement device. The measurement device is provided with an insertion aperture for insertion of a test strip onto which a liquid sample is spotted. The protective cover is attached to the measurement device so as to cover a region including surroundings of the insertion aperture. The protective cover is provided with an opening portion into which the test strip is insertable. The opening portion and the insertion aperture are relatively positioned such that, in a state in which the test strip is inserted through the opening portion and inserted into the insertion aperture, an upper face and lower face of the test strip both abut against the protective cover.Type: ApplicationFiled: September 20, 2023Publication date: May 2, 2024Applicant: ARKRAY, Inc.Inventor: Yuto KANZAKI
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Publication number: 20240139730Abstract: A measurement system including a housing that includes a related information acquisition sensor that acquires related information which is information related to measurement of a measurement target and a display light source that generates display light which is light corresponding to the related information acquired by the related information acquisition sensor, and a measurement device that includes a correspondence relationship storage that stores a correspondence relationship between the related information and the display light in advance, a camera that images the display light to acquire an image, and an information specifying unit that analyzes the image to identify the display light, applies the identified display light to the correspondence relationship stored in the correspondence relationship storage, and specifies the related information.Type: ApplicationFiled: October 25, 2023Publication date: May 2, 2024Applicant: ARKRAY, Inc.Inventor: Toru ODAGAKI
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Publication number: 20240142402Abstract: Provided is a method for analyzing a sample comprising hemoglobin A2 by capillary electrophoresis using an alkaline aqueous solution comprising a cationic polymer, which is the analysis method including the following steps: I) obtaining an electropherogram of the sample by capillary electrophoresis; 2) specifying a detection time Tx of an X peak; 3) specifying a detection time Ta2 of an HbA2 peak; 4) specifying a detection time Ty of a Y peak; 5) calculating a correction coefficient from a relative relationship of the detection time Tx, Ta2, and Ty; 6) calculating a ratio of an HbA2 peak area to a total peak area or a ratio of a Y peak area to the total peak area in an electropherogram; and 7) correcting the ratio of the HbA2 peak area or the ratio of the Y peak area with the correction coefficient.Type: ApplicationFiled: October 12, 2023Publication date: May 2, 2024Applicant: ARKRAY, Inc.Inventor: Naotsugu ONUMA
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Publication number: 20240133820Abstract: A measurement system including: an insertion gate into which a test strip including first and second regions is inserted; a holder accommodating the test strip; a housing including a window facing the test strip; and a smart device including an illuminator illuminating the second region and including a camera imaging the first and second regions, in which the housing includes a mounting part placing the smart device on an outer surface of the housing in a state in which the camera and the illuminator are disposed at positions facing the window, and a measurement light source provided at a position to irradiate the first region, and in a case in which the camera images the first region, the illuminator is turned off while the measurement light source is turned on, and in a case in which the camera images the second region, the illuminator is turned on.Type: ApplicationFiled: October 1, 2023Publication date: April 25, 2024Applicant: ARKRAY, Inc.Inventors: Fumito HIRAMURA, Alexander TURNER
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Patent number: 11959908Abstract: A measurement device includes an acquisition unit and a calculation unit. The acquisition unit acquires a first image obtained by image-capturing liquid containing tangible components flowing through a flow path and a second image image-captured simultaneously with the first image and having an image-capturing magnification higher than the first image. The calculation unit sorts, by using clipped images obtained by clipping the tangible components included in the first image and the second image, the tangible components into different types, and that calculates, by using a total number of the tangible components clipped out of the first image and included in a specified category as well as a ratio of a number of each of the tangible components of the different types clipped out of the second image and included in the specified category relative to a total number thereof, the number of the tangible components included in the specified category.Type: GrantFiled: December 16, 2020Date of Patent: April 16, 2024Assignee: ARKRAY, Inc.Inventor: Yukio Watanabe
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Publication number: 20240102961Abstract: Provided are a sample analysis method comprising: separating hemoglobin in a sample from the sample comprising the hemoglobin, in an alkaline solution by capillary electrophoresis, wherein the alkaline solution comprises a cationic polymer having a secondary amino group and a quaternary ammonium base.Type: ApplicationFiled: September 11, 2023Publication date: March 28, 2024Applicant: ARKRAY, Inc.Inventor: Naotsugu Onuma
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Publication number: 20240102918Abstract: An accuracy management method for executing accuracy management by using an accuracy management substance in a measurement device that measures a biological specimen includes: reading management information regarding the accuracy management substance from an information recording medium; selecting a treatment adapted to the read management information; executing the selected treatment; and updating the management information in the information recording medium according to the executed treatment.Type: ApplicationFiled: September 14, 2023Publication date: March 28, 2024Applicant: ARKRAY, Inc.Inventors: Akira SEZAKI, Hajime FUKUMARU, Takafumi AONO