Patents Assigned to Auspex Pharmaceuticals, Inc.
  • PHENYLALANINE AMIDE INHIBITORS OF ATP-SENSITIVE POTASSIUM CHANNELS
    Publication number: 20100129311
    Abstract: The present invention relates to new phenylalanine amide inhibitors of ATP-sensitive potassium channels, pharmaceutical compositions thereof, and methods of use thereof.
    Type: Application
    Filed: November 23, 2009
    Publication date: May 27, 2010
    Applicant: AUSPEX PHARMACEUTICALS, INC.
    Inventor: Thomas G. Gant
  • PYRIDOINDOLE MODULATORS OF NMDA RECEPTOR AND ACETYLCHOLINESTERASE
    Publication number: 20100125085
    Abstract: The present invention relates to new pyridoindole modulators of NMDA receptors, AMPA receptors, and/or L-type calcium channels, and/or inhibitors of acetylcholinesterase, pharmaceutical compositions thereof, and methods of use thereof.
    Type: Application
    Filed: November 16, 2009
    Publication date: May 20, 2010
    Applicant: AUSPEX PHARMACEUTICALS, INC.
    Inventors: Thomas G. Gant, Manouchehr M. Shahbaz
  • AMIDE INHIBITORS OF RENIN
    Publication number: 20100124550
    Abstract: The present invention relates to new amide inhibitors of renin, pharmaceutical compositions thereof, and methods of use thereof
    Type: Application
    Filed: November 20, 2009
    Publication date: May 20, 2010
    Applicant: AUSPEX PHARMACEUTICALS, INC.
    Inventors: Thomas G. Gant, Manouchehr M. Shahbaz
  • SULFONAMIDE INHIBITORS OF CARBONIC ANHYDRASE II
    Publication number: 20100125067
    Abstract: The present invention relates to new sulfonamide inhibitors of carbonic anhydrase II, pharmaceutical compositions thereof, and methods of use thereof.
    Type: Application
    Filed: November 19, 2009
    Publication date: May 20, 2010
    Applicant: AUSPEX PHARMACEUTICALS, INC.
    Inventor: Thomas G. Gant
  • PYRROLIDINYL MODULATORS OF NICOTINIC ACETYLCHOLINE RECEPTORS
    Publication number: 20100125094
    Abstract: The present invention relates to new pyrrolidinyl modulating nicotinic acetylcholine receptor compounds, pharmaceutical compositions thereof, and methods of use thereof.
    Type: Application
    Filed: November 16, 2009
    Publication date: May 20, 2010
    Applicant: AUSPEX PHARMACEUTICALS, INC.
    Inventors: Thomas G. Gant, Manouchehr M. Shahbaz, Craig Hodulik
  • HYDROXYADAMANTYL INHIBITORS OF DIPEPTIDYLPEPTIDASE IV
    Publication number: 20100124541
    Abstract: The present invention relates to new hydroxyadamantyl inhibitors of dipeptidylpeptidase IV activity, pharmaceutical compositions thereof, and methods of use thereof.
    Type: Application
    Filed: November 17, 2009
    Publication date: May 20, 2010
    Applicant: AUSPEX PHARMACEUTICALS, INC.
    Inventors: Thomas G. Gant, Manouchehr M. Shahbaz
  • BENZISOXAZOLE MODULATORS OF D2 RECEPTOR AND/OR 5-HT2A RECEPTOR
    Publication number: 20100119624
    Abstract: The present invention relates to new benzisoxazole modulators of D2 receptors and/or 5-HT2A receptors, pharmaceutical compositions thereof, and methods of use thereof.
    Type: Application
    Filed: September 17, 2009
    Publication date: May 13, 2010
    Applicant: AUSPEX PHARMACEUTICALS, INC.
    Inventors: Thomas G. Gant, Sepehr Sarshar
  • PHENYLACETIC ACID INHIBITORS OF CYCLOOXYGENASE
    Publication number: 20100119508
    Abstract: The present invention relates to new phenylacetic acid inhibitors of cyclooxygenase activity, pharmaceutical compositions thereof, and methods of use thereof.
    Type: Application
    Filed: November 11, 2009
    Publication date: May 13, 2010
    Applicant: AUSPEX PHARMACEUTICALS, INC.
    Inventors: Thomas G. Gant, Manoucherhr M. Shahbaz
  • 3H-BENZOOXAZOL-2-ONE MODULATORS OF D2 RECEPTOR AND/OR 5-HT1A RECEPTOR
    Publication number: 20100119622
    Abstract: The present invention relates to new 3H-benzooxazol-2-one modulators of D2 receptors and/or 5-HT1A receptors, pharmaceutical compositions thereof, and methods of use thereof.
    Type: Application
    Filed: September 15, 2009
    Publication date: May 13, 2010
    Applicant: AUSPEX PHARMACEUTICALS, INC.
    Inventors: Thomas G. Gant, Sepehr Sarshar
  • BUTYLAMMONIUM MODULATORS OF FATTY ACID TRANSPORT
    Publication number: 20100120917
    Abstract: The present invention relates to new butylammonium modulators of fatty acid transport, and/or removal of toxic acyl-CoA compounds, pharmaceutical compositions thereof, and methods of use thereof
    Type: Application
    Filed: November 10, 2009
    Publication date: May 13, 2010
    Applicant: Auspex Pharmaceuticals, Inc.
    Inventors: Thomas G. Gant, Manouchehr Shahbaz, Craig Hodulik
  • IMIDAZOLYL MODULATORS OF 5-HT3 RECEPTORS
    Publication number: 20100119623
    Abstract: The present invention relates to new imidazolyl modulators of 5-HT3 receptors, pharmaceutical compositions thereof, and methods of use thereof.
    Type: Application
    Filed: September 16, 2009
    Publication date: May 13, 2010
    Applicant: AUSPEX PHARMACEUTICALS, INC.
    Inventors: Thomas G. Gant, Sepehr Sarshar
  • BENZOIC ACID INHIBITORS OF ATP-SENSITIVE POTASSIUM CHANNELS
    Publication number: 20100120861
    Abstract: The present invention relates to new benzoic acid inhibitors of ATP-sensitive potassium channel activity, pharmaceutical compositions thereof, and methods of use thereof.
    Type: Application
    Filed: November 12, 2009
    Publication date: May 13, 2010
    Applicant: AUSPEX PHARMACEUTICALS, INC.
    Inventors: Thomas G. Gant, Sepehr Sarshar
  • PREPARATION AND UTILITY OF SUBSTITUTED IMIDAZOPYRIDINE COMPOUNDS WITH HYPNOTIC EFFECTS
    Publication number: 20100121067
    Abstract: The present disclosure is directed to modulators of GABAA receptors and pharmaceutically acceptable salts and prodrugs thereof, the chemical synthesis thereof, and the medical use of such compounds for the treatment and/or management of sleep disorders and/or for providing a patient in need with a hypnotic, anxiolytic or anti-convulsive effect are described.
    Type: Application
    Filed: September 1, 2009
    Publication date: May 13, 2010
    Applicant: AUSPEX PHARMACEUTICALS, INC.
    Inventors: Thomas G. Gant, Sepehr Sarshar
  • PHENOTHIAZINE MODULATORS OF H1 RECEPTORS
    Publication number: 20100120756
    Abstract: The present invention relates to new phenothiazine modulators of H1 receptors, pharmaceutical compositions thereof, and methods of use thereof.
    Type: Application
    Filed: September 17, 2009
    Publication date: May 13, 2010
    Applicant: AUSPEX PHARMACEUTICALS, INC.
    Inventors: Thomas G. Gant, Sepehr Sarshar
  • STEROID MODULATORS OF GLUCOCORTICOID RECEPTOR
    Publication number: 20100120733
    Abstract: The present invention relates to new steroid modulators of glucocorticoid receptor activity, pharmaceutical compositions thereof, and methods of use thereof.
    Type: Application
    Filed: November 6, 2009
    Publication date: May 13, 2010
    Applicant: AUSPEX PHARMACEUTICALS, INC.
    Inventors: Thomas G. Gant, Manouchehr M. Shahbaz
  • ACETAMIDOPROPANE MODULATORS OF NMDA RECEPTORS
    Publication number: 20100120744
    Abstract: The present invention relates to new acetamidopropane modulators of NMDA receptor, pharmaceutical compositions thereof, and methods of use thereof.
    Type: Application
    Filed: September 18, 2009
    Publication date: May 13, 2010
    Applicant: AUSPEX PHARMACEUTICALS, INC.
    Inventor: Thomas G. Gant
  • PHENOTHIAZINE MODULATORS OF D2 RECEPTORS AND 5-HT2 RECEPTORS
    Publication number: 20100113432
    Abstract: The present invention relates to new phenothiazine modulators of D2 receptor activity and/or 5-HT2 receptor activity, pharmaceutical compositions thereof, and methods of use thereof.
    Type: Application
    Filed: November 4, 2009
    Publication date: May 6, 2010
    Applicant: AUSPEX PHARMACEUTICALS, INC.
    Inventors: Thomas G. Gant, Sepehr Sarshar
  • TRIAZOLE INHIBITORS OF AROMATASE
    Publication number: 20100111901
    Abstract: The present invention relates to new triazole modulators of aromatase activity, pharmaceutical compositions thereof, and methods of use thereof.
    Type: Application
    Filed: November 3, 2009
    Publication date: May 6, 2010
    Applicant: AUSPEX PHARMACEUTICALS, INC.
    Inventors: Thomas G. Gant, Sepehr Sarshar, Manouchehr M. Shahbaz
  • PIPERIDINE MODULATORS OF VMAT2
    Publication number: 20100113496
    Abstract: The present invention relates to new piperidine modulators of VMAT2, nicotinic acetylcholine receptors, and/or ?-opioid receptors, pharmaceutical compositions thereof, and methods of use thereof.
    Type: Application
    Filed: September 22, 2009
    Publication date: May 6, 2010
    Applicant: AUSPEX PHARMACEUTICALS, INC.
    Inventor: Thomas G. Gant
  • METHYLINDAZOLE MODULATORS OF 5-HT3 RECEPTORS
    Publication number: 20100113405
    Abstract: The present invention relates to new methylindazole modulators of 5-HT3 receptor activity, pharmaceutical compositions thereof, and methods of use thereof.
    Type: Application
    Filed: November 4, 2009
    Publication date: May 6, 2010
    Applicant: AUSPEX PHARMACEUTICALS, INC.
    Inventors: Thomas G. Gant, Sepehr Sarshar