Abstract: A swing roller skate with a novel manufacturing process includes: an aluminum insert, a panel, an anti-wear bar, a lower bearing, an upper bearing, an insert plastic wheel fork, a PU wheel and an insert cap, wherein: the aluminum insert is injection-molded into the panel; a front portion of the panel forms a pole, a front end forms a cylinder, a rear portion forms a flat cylinder, a rear end forms a cylinder, and a middle forms a circular sheet; top side holes and bottom side holes are drilled at the front end and the rear end of the panel, and through holes are provided between the top side holes and the bottom side holes; two oval holes are drilled at a circular bottom face of the plane, the anti-wear bar is provided at two sides of a bottom face of the middle portion of the plane.

Abstract: Provided in the present invention are a YAP protein inhibiting polypeptide and application thereof. In particular, the present invention obtains a key binding site of YAP protein and TEAD, screens a polypeptide with best YAP inhibitory activity and modifies the polypeptide, such as adding a disulfide linkage, replacing an amino acid, removing and/or adding (for example, adding a cell-penetrating element), and finally screens and verifies the obtaining of a series of polypeptides with YAP protein activity inhibiting effect and good stability. Experiments show that the polypeptide of the present invention can effectively inhibit the binding activity between YAP protein and TEAD, thus providing good therapeutic effect on digestive tract tumors (especially liver cancer).

Abstract: Provided in the present invention are a YAP protein inhibiting polypeptide and application thereof. In particular, the present invention obtains a key binding site of YAP protein and TEAD, screens a polypeptide with best YAP inhibitory activity and modifies the polypeptide, such as adding a disulfide linkage, replacing an amino acid, removing and/or adding (for example, adding a cell-penetrating element), and finally screens and verifies the obtaining of a series of polypeptides with YAP protein activity inhibiting effect and good stability. Experiments show that the polypeptide of the present invention can effectively inhibit the binding activity between YAP protein and TEAD, thus providing good therapeutic effect on digestive tract tumors (especially liver cancer).

Abstract: Systems and methods disclosed for recommending beauty products for a subject by using a DNA sequencer to generate genetic information; aggregating genetic information, beauty trend data, and cosmetic product response from a patient population; deep learning with a computer to generate at least one computer implemented classifier that predicts matching beauty products based on the genetic information, beauty trend data, and cosmetic product response from a patient population; and recommending one or more beauty products for the subject.

Abstract: A miniature circuit breaker with quick current breaking capability which includes a miniature circuit breaker body, a current transformer CT1, a zero-sequence current transformer CT2 and a smart controller module. The miniature circuit breaker body is internally provided with a main arc extinguishing chamber, a fixed contact, a movable contact, a tripping mechanism, and a magnetic tripping push rod. The tripping mechanism includes a lock catch, a movable contact rocker arm, a jump pin, a connecting rod, and a tension spring. A rotated-hinge repulsive force structure is applied between the fixed contact and the movable contact. The tripping mechanism is further provided with a torsional spring to press the movable contact close to the fixed contact. A shunt tripping device controlling the miniature circuit breaker switch to be turned off is arranged in the smart controller module.

Abstract: An intelligent anti-theft zipper includes a zipper tape, a zipper head and an intelligent anti-theft module. The intelligent anti-theft module includes a control signal switch, an alarm unit and a power supply. The control signal switch includes a first switch component and a second switch component cooperating with each other. The first switch component is fixed on the zipper head; the second switch component is fixed on the zipper tape or an object mounted with the zipper, the installation position of the second switch component corresponds to the position of the zipper head when the zipper is fully closed. The control signal switch generates and outputs a control signal to the alarm unit to provide an alarm when the first switch component deviates from the second switch component for a predetermined distance.

Abstract: A miniature circuit breaker with quick current breaking capability which includes a miniature circuit breaker body, a current transformer CT1, a zero-sequence current transformer CT2 and a smart controller module. The miniature circuit breaker body is internally provided with a main arc extinguishing chamber, a fixed contact, a movable contact, a tripping mechanism, and a magnetic tripping push rod. The tripping mechanism includes a lock catch, a movable contact rocker arm, a jump pin, a connecting rod, and a tension spring. A rotated-hinge repulsive force structure is applied between the fixed contact and the movable contact. The tripping mechanism is further provided with a torsional spring to press the movable contact close to the fixed contact. A shunt tripping device controlling the miniature circuit breaker switch to be turned off is arranged in the smart controller module.

Abstract: Provided in the present invention are a YAP protein inhibiting polypeptide and application thereof. In particular, the present invention obtains a key binding site of YAP protein and TEAD, screens a polypeptide with best YAP inhibitory activity and modifies the polypeptide, such as adding a disulfide linkage, replacing an amino acid, removing and/or adding (for example, adding a cell-penetrating element), and finally screens and verifies the obtaining of a series of polypeptides with YAP protein activity inhibiting effect and good stability. Experiments show that the polypeptide of the present invention can effectively inhibit the binding activity between YAP protein and TEAD, thus providing good therapeutic effect on digestive tract tumors (especially liver cancer).

Abstract: The present invention relates to a processing method for a vacuum container and a vacuum container, characterized in that, the processing method for a vacuum container comprising a step of welding a sealing fin, wherein welding a sealing fin onto an inner wall of an outer container, and leaving an empennage for welding at the bottom of the outer container; and a step of welding an outer bottom cap, wherein welding an outer bottom cap seamlessly on the empennage by means of argon arc welding.

Abstract: A smart vehicle can be operated by generating a 3D model of a sensor's field of view; receiving information from neighboring vehicles to compensate for blindspots in the sensor's field of view and in a driver's field of view; receiving traffic information, weather information; adjusting one or more characteristics of the plurality of 3D models based on the received traffic and weather information and blindspot information; aggregating the plurality of 3D models to generate a comprehensive 3D model; and combining the comprehensive 3D model with detailed map information; and using the combined comprehensive 3D model with detailed map information to maneuver the vehicle.

Abstract: The present invention relates to a processing method for a vacuum container and a vacuum container, characterized in that, the processing method for a vacuum container comprising a step of welding a sealing fin, wherein welding a sealing fin onto an inner wall of an outer container, and leaving an empennage for welding at the bottom of the outer container; and a step of welding an outer bottom cap, wherein welding an outer bottom cap seamlessly on the empennage by means of argon arc welding.

Abstract: A valve unit includes a valve body with a plate located in a tubular portion of the valve body. The tubular portion has multiple notches defined in the outside there. A knob has a space defined therein and is threadedly mounted to the tubular portion. The knob has a groove defined in the outside thereof. A first hole and a second hole are respectively defined through knob and communicate with the groove. A resilient member is engaged with the groove and two ends of the resilient member are respectively engaged with the first and second holes. A spring is biased between the plate and the knob. The contact portion is engaged with the notches to generate sounds when rotating the knob.

Abstract: Provided in the present invention are a YAP protein inhibiting polypeptide and application thereof. In particular, the present invention obtains a key binding site of YAP protein and TEAD, screens a polypeptide with best YAP inhibitory activity and modifies the polypeptide, such as adding a disulfide linkage, replacing an amino acid, removing and/or adding (for example, adding a cell-penetrating element), and finally screens and verifies the obtaining of a series of polypeptides with YAP protein activity inhibiting effect and good stability. Experiments show that the polypeptide of the present invention can effectively inhibit the binding activity between YAP protein and TEAD, thus providing good therapeutic effect on digestive tract tumors (especially liver cancer).

Abstract: A feet-swinging-type roller skate of concave plastic panel (1) comprises a concave plastic panel (1) and a universal wheel (2). The top of the two concave plastic panels (1) is in the shape of a concave. The front top and rear top of the concave plastic panel (1) are respectively provided with the universal wheel (2) on their lower ends. The feet-swinging-type roller skate of concave plastic panel (1) should be used in pairs.

Abstract: A transformer includes at least one primary interface winding, at least one secondary interface winding, in which at least part of the primary interface winding is formed on an insulating device or insulator. At least part of the primary interface winding and at least part of the secondary interface winding collectively form a noise reduction mechanism.

Abstract: Disclosed is a control device for a cordless blind with willful stop at any positions according to user needs during switching operation. The control device primarily comprises a force-return mechanism, a shaft connector, and a braking buffer mechanism which are all installed inside a same housing. The force-return mechanism has a flat spring bevel gear and an elastic element. One end of the shaft connector is a transmission bevel gear meshed with the flat spring bevel gear. The braking buffer mechanism includes a friction ring and an impeding spring where the friction ring is immovably fixed inside the housing with a wear-proof annular inwall. The impeding spring is tightly plugged into the friction ring with an extrusion to prevent the rotation of the transmission bevel gear. Specifically, the shaft connector has a trigger to change the friction between the impeding spring and the friction ring.

Abstract: A blow gun includes a body with a top path and a bottom path, and a volume adjustment device is installed between the top and bottom paths. The volume adjustment device is in contact with a press rod which has one end pivotably connected to the body. The opening of the press rod is controlled by operation of the volume adjustment device so as to change the volume of the pressurized air. The press rod can also be locked at a position so that it is not activated unintentionally.