Patents Assigned to BASF
  • Patent number: 5741892
    Abstract: The present invention provides anti-tumor peptides of Formula I,A-B-N (CH.sub.3)-CHD-CH(OCH.sub.3)-CH.sub.2 CO-Pro-Pro-K (I),and the acid salts thereof. A is an amino acid residue of the formula (CH.sub.3).sub.2 N--CHX--CO, wherein X is a normal or branched alkyl group. B is an amino acid residue selected from the group consisting of valyl, isoleucyl, leucyl, and 2-t-butylglycyl. D is a normal or branched C.sub.3 -C.sub.4 -alkyl group. K is a t-butoxy group or a substituted amino group.An additional embodiment of the present invention is a method for treating a malignancy in a mammal, such as a human, comprising administering to the mammal an effective amount of a compound or compounds of Formula I in a pharmaceutically acceptable composition.
    Type: Grant
    Filed: July 30, 1996
    Date of Patent: April 21, 1998
    Assignee: Basf Aktiengesellschaft
    Inventors: Teresa Barlozzari, Andreas Haupt, Bernd Janssen, Christian Griesinger, Daniel Belik, Michael Boretzky, George R. Pettit
  • Patent number: 5741519
    Abstract: A process for producing active substance compositions in the form of a solid solution of the active substance in a polymer matrix, which comprises melt extrusion of the active substance in nonionic form together with a polymer and a salt.
    Type: Grant
    Filed: November 21, 1996
    Date of Patent: April 21, 1998
    Assignee: BASF Aktiengesellschaft
    Inventors: Joerg Rosenberg, Jorg Breitenbach
  • Patent number: 5741851
    Abstract: There is a provided a stable low viscosity graft polymer dispersion comprising from 25 to 60 weight percent based on the total weight of the polymer dispersion of at least three ethylenically unsaturated monomers polymerized in the presence of a reaction moderator and a free radical initiator in a polyol mixture initially containing less than 0.1 moles of induced unsaturation per mole of said polyol mixture. One of the monomers in the mixture of ethylenically unsaturated monomers is a hydroxylfunctional or aminofunctional C.sub.2 -C.sub.6 alkyl methacrylate.
    Type: Grant
    Filed: August 30, 1995
    Date of Patent: April 21, 1998
    Assignee: BASF Corporation
    Inventors: Duane A. Heyman, James A. Gallagher
  • Patent number: 5741827
    Abstract: Flame-resistant flexible polyurethane foams are produced by reactinga) organic and/or modified organic polyisocyanates,b) relatively high molecular weight compounds containing at least two reactive hydrogen atoms andc) if desired, low molecular weight chain extenders in the presence ofd) catalysts,e) blowing agentsf) flame retardants,and, if desiredg) auxiliaries and/or additives,where the flame retardants f) used are melamine in combination with at least one anionic dispersant.
    Type: Grant
    Filed: August 28, 1996
    Date of Patent: April 21, 1998
    Assignee: BASF Aktiengesellschaft
    Inventors: Sarbananda Chakrabarti, Stefan Fox, Jurgen Schneider, Klaus Schmutzer
  • Patent number: 5741947
    Abstract: Alkoxylation products are prepared by reacting compounds having active hydrogen atoms with C.sub.2 -C.sub.4 -alkylene oxides in the presence of a mixed hydroxide built up of polycations and modified with additives and having the general formula I or II?M(II).sub.1-x M(III).sub.x (OH).sub.2 !A.sub.x/n .multidot.m L(I)?LiAl.sub.2 (OH).sub.6 !A.sub.1/n .multidot.m L (II)whereM(II) is at least one divalent metal ion,M(III) is at least one trivalent metal ion,A is at least one inorganic anion andL is an organic solvent or water,n is the valence of the inorganic anion A or in the case of a plurality of anions A is their mean valence andx can assume a value of from 0.1 to 0.5 andm can assume a value of from 0 to 10,as alkoxylation catalyst, wherein the mixed hydroxide contains additives.
    Type: Grant
    Filed: January 29, 1996
    Date of Patent: April 21, 1998
    Assignee: BASF Aktiengesellschaft
    Inventors: Gerhard Wolf, Bernd Burkhart, Guenter Lauth, Horst Trapp, Alfred Oftring
  • Patent number: 5741862
    Abstract: Highly flexible propylene/ethylene copolymers having a high rubber content are obtainable by two-stage polymerization from the gas phase in an agitated fixed bed by means of a Ziegler-Natta catalyst system which, in addition to a titanium-containing solid component, also contains an aluminum compound as a cocatalyst, in a first polymerization stage, propylene being polymerized at from 15 to 40 bar and from 50.degree. to 90.degree. C. and during an average residence time of the reaction mixture of from 0.5 to 5 hours and then, in a second polymerization stage, a mixture of propylene and ethylene being polymerized with the polymer discharged from the first polymerization stage, at from 5 to 30 bar, this pressure being at least 2 bar below the pressure of the first polymerization stage, and at from 60.degree. to 100.degree. C. and during an average residence time of the reaction mixture of from 0.
    Type: Grant
    Filed: January 13, 1997
    Date of Patent: April 21, 1998
    Assignee: BASF Aktiengesellschaft
    Inventors: Patrik Muller, Meinolf Kersting
  • Patent number: 5741753
    Abstract: Essentially nitrate-free catalyst for the wash-and-wear finishing of textiles with formaldehyde-free crosslinkers, comprising magnesium, tetrafluoroborate, chloride and sulfate ions in the molar weight ratios of(a) Mg.sup.2+ : BF.sub.4.sup.- =1:0.1 to 1:4,(b) Mg.sup.2+ : Cl.sup.- =1:1.7 to 1:15 and(c) SO.sub.4.sup.2- : Cl.sup.- =1:0.2 to 1:4.
    Type: Grant
    Filed: June 6, 1996
    Date of Patent: April 21, 1998
    Assignee: BASF Aktiengesellschaft
    Inventors: Pia Hois, Toni Simenc
  • Patent number: 5741829
    Abstract: Radiation-curable (meth)acrylates obtainable by reacting compounds of the formula ##STR1## in which R is C.sub.1 -C.sub.4 -alkyl, aryl or R.sup.1 and R.sup.1 is ##STR2## in which R.sup.2 to R.sup.6 independently of one another are H, C.sub.1 -C.sub.4 -alkyl, C.sub.1 -C.sub.4 -alkoxy, OH, phenyl, SH, SCH.sub.3, SC.sub.2 H.sub.5, F, Cl, Br, CN, COOH, COO--(C.sub.1 -C.sub.17 -alkyl), COO--(C.sub.5 -C.sub.10 -aryl), CF.sub.3, N(alkyl).sub.2, N(alkyl)(aryl), N(aryl).sub.2, N.sup..sym. (alkyl).sub.3 A.sup..crclbar., N.sup..sym. H(alkyl).sub.2 A.sup..crclbar., A.sup..crclbar. is the anion of an acid, and alkyl or aryl, unless indicated otherwise, is C.sub.1 -C.sub.10 -alkyl or C.sub.5 -C.sub.10 -aryl, respectively, and at least one but not more than 3 of R.sup.2 to R.sup.6 are ##STR3## with hydroxy(meth)acrylates containing at least 1 free hydroxyl group and at least 2 (meth)acrylic groups in the molecule.
    Type: Grant
    Filed: July 3, 1996
    Date of Patent: April 21, 1998
    Assignee: BASF Aktiengesellschaft
    Inventors: Wolfgang Reich, Erich Beck, Ulrich Jager, Reinhold Schwalm
  • Patent number: 5739400
    Abstract: Preparation of O-(2-hydroxyalkyl)oximes I ##STR1## (R.sup.1 and R.sup.2 =alkyl or R.sup.1 and R.sup.2 and the C atom which carries them=5- to 7-membered cycloalkyl), by catalytically hydrogenating an O-(2,3-epoxyalkyl)oxime of the general formula II ##STR2## using hydrogen. The products I are suitable as intermediates for herbicides.
    Type: Grant
    Filed: February 3, 1997
    Date of Patent: April 14, 1998
    Assignee: BASF Aktiengesellschaft
    Inventors: Albrecht Harreus, Norbert Gotz, Harald Rang
  • Patent number: 5739405
    Abstract: A process for the preparation of amines of the general formula I ##STR1## in which R.sup.1, R.sup.2, R.sup.3, R.sup.4, R.sup.5, R.sup.6 denote hydrogen, C.sub.1 -C.sub.20 alkyl, C.sub.2 -C.sub.20 alkenyl, C.sub.2 -C.sub.20 alkynyl, C.sub.3 -C.sub.20 cycloalkyl, C.sub.4 -C.sub.20 alkylcycloalkyl, C.sub.4 -C.sub.20 cycloalkylalkyl, aryl, C.sub.7 -C.sub.20 alkylaryl, or C.sub.7 -C.sub.20 aralkyl,R.sup.1 and R.sup.2 together denote a saturated or unsaturated C.sub.3 -C.sub.9 alkylene dichain andR.sup.3 or R.sup.5 denotes C.sub.21 -C.sub.200 alkyl, C.sub.21 -C.sub.200 alkenyl or they together form a C.sub.2 -C.sub.12 alkylene dichain,by the reaction of olefins of the general formula II ##STR2## in which R.sup.3, R.sup.4, R.sup.5, and R.sup.6 have the above meanings, with ammonia or primary or secondary amines of the general formula III ##STR3## in which R.sup.1 and R.sup.2 have the above meanings, at temperatures ranging from 200.degree. to 350.degree. C.
    Type: Grant
    Filed: December 4, 1996
    Date of Patent: April 14, 1998
    Assignee: BASF Aktiengesellschaft
    Inventors: Karsten Eller, Rudolf Kummer, Peter Stops
  • Patent number: 5739190
    Abstract: A process for the preparation of a stable water-in-oil emulsion of a hydrolyzed polymer of an N-vinyl amide of the formula ##STR1## in which R and R.sup.1 denote H or C.sub.1 -C.sub.6 alkyl, by the polymerization of a compound of the formula I alone or in admixture with another ethylenically unsaturated monomer in the presence of a polymerization initiator and emulsifier in the form of a water-in-oil emulsion, to form a water-in-oil polymeric emulsion, followed by hydrolysis of the polymer in the form of the water-in-oil polymeric emulsion in the presence of an acid or base and from 1 to 30 wt %, based on the polymer, of an emulsifier, the emulsifier used being a mixture of(a) from 5 to 95 wt % of a block or graft copolymer of the structure (A-B)m, (A)-B or (B)-A, in which in each case(a) from 5 to 95 wt % of a block or graft copolymer of the structure (A-B).sub.m, (A).sub.n B or (B).sub.
    Type: Grant
    Filed: November 21, 1996
    Date of Patent: April 14, 1998
    Assignee: BASF Aktiengesellschaft
    Inventors: Heinrich Hartmann, Karl-Heinrich Schneider, Walter Denzinger, Claudia Nilz, Dietmar Monch
  • Patent number: 5739375
    Abstract: Methyl compounds are prepared from carbon acids by reaction with dimethyl carbonate in the presence of a nitrogen-containing base.
    Type: Grant
    Filed: April 4, 1997
    Date of Patent: April 14, 1998
    Assignee: BASF Aktiengellschaft
    Inventor: Rolf Fischer
  • Patent number: 5739122
    Abstract: Dextran esters with a molecular weight of 10,000-10,000,000 and ester side chains which are derived from acids with 6-18 carbon atoms, where the degree of esterification is adjusted, depending on the number of carbon atoms in the side chains and the molecular weight, to a value of 0.04-1.1 so that the dextran esters are insoluble in water at room temperature and are broken down by colonic bacteria, and their use for coating and/or embedding pharmaceutical active ingredients or drug formulations.
    Type: Grant
    Filed: March 11, 1996
    Date of Patent: April 14, 1998
    Assignee: BASF Aktiengesellschaft
    Inventors: Volker Schehlmann, Kurt Heinz Bauer, Jan-Frederic Kesselhut
  • Patent number: 5738805
    Abstract: An improved technique is provided that is capable of accomplishing the expeditious dissolution of gluten (e.g., vital wheat gluten or corn gluten) in water that normally is capable of absorbing water without dissolution. An effective solubilizing concentration of a polysaccharide that contains uronic acid residues is dissolved in the aqueous solvent when contacted with agitation with the gluten component at an elevated temperature. The formation of a substantially homogeneous aqueous solution of the gluten is accomplished with ease without the necessity to resort to the introduction of acids, bases, enzymes, or other solvents as practiced in the prior art. The resulting aqueous solution of gluten is completely edible and is suitable for the controlled uniform introduction of such gluten into association with a variety of food products where it can serve a binding, adhesive, microencapsulation, film-forming, and/or coating function.
    Type: Grant
    Filed: September 3, 1996
    Date of Patent: April 14, 1998
    Assignee: BASF Corporation
    Inventors: Frederick K. Chaundy, Scott P. Melidosian, Jeffrey L. Finnan
  • Patent number: 5739343
    Abstract: Nitro dyes of the formula ##STR1## where X.sup.1 and X.sup.2 are hydrogen, C.sub.1 -C.sub.6 -alkyl, C.sub.1 -C.sub.6 -alkoxy or pyrrolidin-2-on-1-yl,X.sup.3 is hydrogen or C.sub.1 -C.sub.6 -alkyl, andX.sup.4 is a radical of the formula ##STR2## where R.sup.1 is hydrogen, substituted or unsubstitued C.sub.1 -C.sub.12 -alkyl, substituted or unsubstituted C.sub.3 -C.sub.7 -cycloalkyl or substituted or unsubstituted phenyl,R.sup.2 and R.sup.3 are hydrogen, C.sub.1 -C.sub.6 -alkyl or C.sub.1 -C.sub.6 -alkoxy,R.sup.4 is hydrogen, methyl, ethyl, methoxy or ethoxy, andR.sup.5 is hydrogen or C.sub.1 -C.sub.6 -alkyl,are useful for dyeing or printing textile materials.
    Type: Grant
    Filed: January 21, 1997
    Date of Patent: April 14, 1998
    Assignee: BASF Aktiengesellschaft
    Inventors: Gunther Lamm, Helmut Reichelt, Clemens Grund
  • Patent number: 5739391
    Abstract: A process for the catalytic gas-phase oxidation of acrolein to acrylic acid in a multiple contact tube fixed-bed reactor through whose space surrounding the contact tubes only one heat-exchange medium circuit is passed, at elevated temperature on catalytically active multimetal oxides with an acrolein conversion for a single pass of .gtoreq.95 mol % and an acrylic acid formation selectivity of .gtoreq.
    Type: Grant
    Filed: September 8, 1995
    Date of Patent: April 14, 1998
    Assignee: BASF Aktiengesellschaft
    Inventors: Wilhelm Ruppel, Ulrike Wegerle, Andreas Tenten, Ulrich Hammon
  • Patent number: 5739402
    Abstract: Preparation of mixtures of O-phenoxyalkylhydroxylamines Ia and Ib ##STR1## and the corresponding salt mixtures by a) converting mixtures of isomers of O-(2-hydroxyethyl)oximes IIa and IIb ##STR2## with a sulfonyl halide III ##STR3## into a mixture of sulfonates IVa and IVb ##STR4## b) reacting this mixture of IVa and IVb with a phenol HO-Ar (V) to give a mixture of O-phenoxyalkoximes VIa and VIb ##STR5## c) hydrolyzing this mixture in the presence of an acid and, if desired d) liberating the O-phenoxyalkylhydroxylamines Ia and Ib from the resulting salts using a mineral acid.Compounds Ia/Ib and VIa/VIb are important intermediates for crop protection agents.
    Type: Grant
    Filed: November 4, 1996
    Date of Patent: April 14, 1998
    Assignee: BASF Aktiengesellschaft
    Inventors: Harald Rang, Norbert Gotz, Albrecht Harreus, Dirk Borchers, Horst Hartmann, Volker Maywald, Frank Heimann, Thomas Buschulte
  • Patent number: 5738801
    Abstract: Hydrophobic silica aerogels obtainable by reacting a waterglass solution with an acid at a pH of from 7.5 to 11, substantially removing ionic constituents from the resulting silica hydrogels by washing with water or dilute aqueous solutions of inorganic bases, while the pH of the hydrogels is kept in the range from 7.5 to 11, displacing the aqueous phase contained in the hydrogel by an alcohol, and subsequent supercritical drying of the resulting alcogels.
    Type: Grant
    Filed: February 29, 1996
    Date of Patent: April 14, 1998
    Assignee: BASF Aktiengesellschaft
    Inventors: Bernd Ziegler, Norbert Mronga, Friedhelm Teich, Gunter Herrmann
  • Patent number: 5739324
    Abstract: A process for preparing cyclic lactams by reacting amino carbonitriles with water in liquid phase in the presence of heterogeneous catalysts based on titanium dioxide, zirconium oxide, cerium oxide and aluminum oxide.
    Type: Grant
    Filed: May 16, 1996
    Date of Patent: April 14, 1998
    Assignee: BASF Aktiengesellschaft
    Inventors: Eberhard Fuchs, Tom Witzel
  • Patent number: D393522
    Type: Grant
    Filed: October 22, 1996
    Date of Patent: April 14, 1998
    Assignee: BASF Corporation
    Inventors: Billy R. Pettis, Randy L. Vaughn, Richard E. Dombkowski, Brad S. Filson