Patents Assigned to Baxter International Inc.
  • Patent number: 11116696
    Abstract: A reconstitution device includes: a piercing member having a first end and a second end, the first end of the piercing member configured to engage an administration port; a delivery member having a first end and a second end, the first end of the delivery member configured to engage a delivery site; a collar configured to engage a vial; and a cap extending from the collar and holding the piercing member and the delivery member such that the second end of the piercing member and the second end of the delivery member are disposed within the cylindrical collar.
    Type: Grant
    Filed: August 10, 2017
    Date of Patent: September 14, 2021
    Assignees: BAXTER INTERNATIONAL INC., BAXTER HEALTHCARE SA
    Inventors: Freddy Desbrosses, Pierpaolo Padula, Virgil Claudiu Manta, Valentin Champain
  • Patent number: 11116410
    Abstract: The invention provides a body-worn patch sensor for simultaneously measuring a blood pressure (BP), pulse oximetry (SpO2), and other vital signs and hemodynamic parameters from a patient. The patch sensor features a sensing portion having a flexible housing that is worn entirely on the patient's chest and encloses a battery, wireless transmitter, and all the sensor's sensing and electronic components. It measures electrocardiogram (ECG), impedance plethysmogram (IPG), photoplethysmogram (PPG), and phonocardiogram (PCG) waveforms, and collectively processes these to determine the vital signs and hemodynamic parameters. The sensor that measures PPG waveforms also includes a heating element to increase perfusion of tissue on the chest.
    Type: Grant
    Filed: July 24, 2018
    Date of Patent: September 14, 2021
    Assignees: Baxter International Inc., Baxter Healthcare SA
    Inventors: Erik Tang, Matthew Banet, Marshal Dhillon, James McCanna, Mark Dhillon
  • Patent number: 11116895
    Abstract: An infusion pump is provided for pumping fluid through an administrative set at a desired flow rate over a specified duration, and includes a pumping mechanism for releasably receiving and for exerting a pulsing force on the administrative set, thus pressurizing a portion of the set for creating a flow of fluid from a set outlet. A controller is connected to and is configured for operating the pumping mechanism, the controller determines a pulse frequency based on a volume of fluid infused over a portion of the specified duration and the desired flow rate, outputs a control signal to the pumping mechanism for operating the pumping mechanism based on the determined pulse frequency, determines a first pulse frequency based on the desired flow rate; and adjusts the first pulse frequency based on the volume of fluid infused to provide a second pulse frequency being different from the first pulse frequency.
    Type: Grant
    Filed: February 8, 2018
    Date of Patent: September 14, 2021
    Assignees: BAXTER INTERNATIONAL INC., BAXTER HEALTHCARE S.A.
    Inventors: Patrick Michael Hopkins, Harry John Weber, Haonan Sun
  • Publication number: 20210275470
    Abstract: A packaged, sealed container system for stable storage of a formulation of an oxygen-sensitive pharmaceutical compound, the packaged, sealed container system comprising a primary container including therein a formulation of an oxygen-sensitive pharmaceutical compound, a secondary outer container comprising a first flexible sheet layer, an opposing second flexible sheet layer, and a seal disposed along a common peripheral edge of the first and second flexible sheet layers, such that the primary container is disposed between and enclosed by the first and second flexible sheet layers of the secondary outer container. An oxygen scavenger is also disposed between and enclosed by the first and second flexible sheet layers of the secondary outer container. The oxygen scavenger is in fluid communication with the contents of the primary container.
    Type: Application
    Filed: March 8, 2021
    Publication date: September 9, 2021
    Applicants: BAXTER INTERNATIONAL INC., BAXTER HEALTHCARE SA
    Inventors: Steven M. Cope, Allan E. Titus
  • Patent number: 11096590
    Abstract: The invention provides a body-worn patch sensor for simultaneously measuring a blood pressure (BP), pulse oximetry (SpO2), and other vital signs and hemodynamic parameters from a patient. The patch sensor features a sensing portion having a flexible housing that is worn entirely on the patient's chest and encloses a battery, wireless transmitter, and all the sensor's sensing and electronic components. It measures electrocardiogram (ECG), impedance plethysmogram (IPG), photoplethysmogram (PPG), and phonocardiogram (PCG) waveforms, and collectively processes these to determine the vital signs and hemodynamic parameters. The sensor that measures PPG waveforms also includes a heating element to increase perfusion of tissue on the chest.
    Type: Grant
    Filed: July 24, 2018
    Date of Patent: August 24, 2021
    Assignees: BAXTER INTERNATIONAL INC., BAXTER HEALTHCARE SA
    Inventors: Erik Tang, Matthew Banet, Marshal Dhillon, James McCanna, Mark Dhillon
  • Patent number: 11097041
    Abstract: Dialysis is enhanced by using nanoclay sorbents to better absorb body wastes in a flow-through system. The nanoclay sorbents, using montmorillonite, bentonite, and other clays, absorb significantly more ammonium, phosphate, and creatinine, and the like, than conventional sorbents. The montmorillonite, the bentonite, and the other clays may be used in wearable systems, in which a dialysis fluid is circulated through a filter with the nanoclay sorbents. Waste products are absorbed by the montmorillonite, the bentonite, and the other clays and the dialysis fluid is recycled to a patient's peritoneum. Using an ion-exchange capability of the montmorillonite, the bentonite, and the other clays, waste ions in the dialysis fluid are replaced with desirable ions, such as calcium, magnesium, and bicarbonate. The nanoclay sorbents are also useful for refreshing a dialysis fluid used in hemodialysis and thus reducing a quantity of the dialysis fluid needed for the hemodialysis.
    Type: Grant
    Filed: May 15, 2019
    Date of Patent: August 24, 2021
    Assignees: Baxter International Inc., Baxter Healthcare SA
    Inventors: Rosa H. Yeh, Wei Xie, Hsinjin E. Yang, Michael T. K. Ling, Ying-Cheng Lo
  • Patent number: 11092604
    Abstract: The present invention provides a glucose sensor having a glucose receptor containing a binding site of formula (I): wherein X, n, m and R1 are defined herein. Also provided is a glucose sensor molecule for use in such a glucose sensor, the glucose sensor molecule containing the binding site of formula (I). The binding site has been found to have particularly good selectivity for glucose.
    Type: Grant
    Filed: November 19, 2015
    Date of Patent: August 17, 2021
    Assignees: Baxter International Inc., Baxter Healthcare SA
    Inventors: Nicholas Paul Barwell, Tony James
  • Patent number: 11090421
    Abstract: Methods, sorbent cartridges and cleaning devices are disclosed for refurbishing sorbent materials. In one implementation among multiple implementations, a medical fluid delivery method includes: providing a sorbent cartridge including H+ZP within a casing for a treatment; and after the treatment, refurbishing the H+ZP while maintained within the casing via (i) regenerating the non-disinfected H+ZP by flowing an acid solution through the casing, (ii) rinsing the regenerated H+ZP while maintained within the casing, (iii) disinfecting the regenerated and rinsed H+ZP by flowing a disinfecting agent through the casing, and (iv) rinsing the regenerated and disinfected H+ZP while maintained within the casing. Multiple batch sorbent refubishing implementations are also disclosed.
    Type: Grant
    Filed: November 28, 2018
    Date of Patent: August 17, 2021
    Assignees: Baxter International Inc., Baxter Healthcare SA
    Inventors: Yuanpang Samuel Ding, Rosa Hung-Chen Yeh, Cristian Adolfo Menzel Bueno, Ieng Kin Lao
  • Patent number: 11083827
    Abstract: A medical fluid delivery system includes: a medical fluid delivery machine including a component having at least one of associated output data or associated test data; at least one of a (i) component output replacement limit and a component output soft limit for the component or (ii) a component testing replacement limit or a component testing soft limit for the component; and a computer programmed to store at least one of (i) or (ii), and for (i) analyze the output data to provide a first indication of how well the component is performing relative to the component output replacement limit and the component output soft limit, and for (ii) analyze the test data to provide a second indication of how well the at least one component is testing relative to the component testing replacement limit and the component testing soft limit.
    Type: Grant
    Filed: August 28, 2017
    Date of Patent: August 10, 2021
    Assignees: Baxter International Inc., Baxter Healthcare SA
    Inventors: Shawn Collin Oppegard, Marc Alexander Barten
  • Patent number: 11071804
    Abstract: The present invention provides a hemostatic composite sponge comprising oxidized cellulose and an essentially gelatin-free bioadhesive material stably associated with said sponge and present in an organized pattern on said sponge.
    Type: Grant
    Filed: December 15, 2017
    Date of Patent: July 27, 2021
    Assignees: Baxter International Inc., Baxter Healthcare SA
    Inventors: Hans Christian Hedrich, Joris Hoefinghoff, Woonza M. Rhee, Atsushi Edward Osawa
  • Patent number: 11071479
    Abstract: A handheld device measures all vital signs and some hemodynamic parameters from the human body and transmits measured information wirelessly to a web-based system, where the information can be analyzed by a clinician to help diagnose a patient. The system utilizes our discovery that bio-impedance signals used to determine vital signs and hemodynamic parameters can be measured over a conduction pathway extending from the patient's wrist to a location on their thoracic cavity, e.g. their chest or navel. The device's form factor can include re-usable electrode materials to reduce costs. Measurements made by the handheld device, which use the belly button as a ‘fiducial’ marker, facilitate consistent, daily measurements, thereby reducing positioning errors that reduce accuracy of standard impedance measurements. In this and other ways, the handheld device provides an effective tool for characterizing patients with chronic diseases, such as heart failure, renal disease, and hypertension.
    Type: Grant
    Filed: October 8, 2018
    Date of Patent: July 27, 2021
    Assignees: BAXTER INTERNATIONAL INC., BAXTER HEALTHCARE SA
    Inventors: Matthew Banet, Marshal Singh Dhillon, Susan Meeks Pede, Lauren Nicole Miller Hayward, Arthur Deptala, Jonas Dean Cochran
  • Patent number: 11064918
    Abstract: The invention provides a body-worn patch sensor for simultaneously measuring a blood pressure (BP), pulse oximetry (SpO2), and other vital signs and hemodynamic parameters from a patient. The patch sensor features a sensing portion having a flexible housing that is worn entirely on the patient's chest and encloses a battery, wireless transmitter, and all the sensor's sensing and electronic components. It measures electrocardiogram (ECG), impedance plethysmogram (IPG), photoplethysmogram (PPG), and phonocardiogram (PCG) waveforms, and collectively processes these to determine the vital signs and hemodynamic parameters. The sensor that measures PPG waveforms also includes a heating element to increase perfusion of tissue on the chest.
    Type: Grant
    Filed: July 24, 2018
    Date of Patent: July 20, 2021
    Assignees: BAXTER INTERNATIONAL INC., BAXTER HEALTHCARE SA
    Inventors: Erik Tang, Matthew Banet, Marshal Dhillon, James McCanna
  • Patent number: 11058809
    Abstract: A handheld personal communication apparatus for dialysis includes a reader to (i) read a marking displayed on a dialysis fluid container to acquire data concerning at least one of a dialysis fluid type or a dialysis fluid volume from the marking, and/or (ii) receive a patient weight signal from a weight scale; a processor using at least one of the dialysis fluid type, dialysis fluid volume, or patient weight to determine a dialysis dwell time for at least one cycle of a dialysis therapy, the dialysis dwell time being a time to achieve, over the at least one cycle, at least one of (a) a specified ultrafiltrate level, (b) a urea removal level, or (c) a creatinine removal level; and an output interface providing an indication to the patient of a completion of the dialysis dwell time.
    Type: Grant
    Filed: October 21, 2019
    Date of Patent: July 13, 2021
    Assignees: Baxter International Inc., Baxter Healthcare SA
    Inventors: Bijan Elahi, Ying-Cheng Lo, Vikram Prabhakar Mehendale
  • Patent number: 11058340
    Abstract: The invention provides a neck-worn sensor for simultaneously measuring a blood pressure (BP), pulse oximetry (SpO2), and other vital signs and hemodynamic parameters from a patient. The neck-worn sensor features a sensing portion having a flexible housing that is worn entirely on the patient's chest and encloses a battery, wireless transmitter, and all the sensor's sensing and electronic components. It measures electrocardiogram (ECG), impedance plethysmogram (IPG), photoplethysmogram (PPG), and phonocardiogram (PCG) waveforms, and collectively processes these to determine the vital signs and hemodynamic parameters. The sensor that measures PPG waveforms also includes a heating element to increase perfusion of tissue on the chest.
    Type: Grant
    Filed: July 24, 2018
    Date of Patent: July 13, 2021
    Assignees: BAXTER INTERNATIONAL INC., BAXTER HEALTHCARE SA
    Inventors: Erik Tang, Matthew Banet, Marshal Dhillon, James McCanna, Mark Dhillon
  • Patent number: 11052180
    Abstract: A system and method for balancing flows of renal replacement fluid is disclosed. The method uses pressure controls and pressure sensing devices to more precisely meter and balance the flow of fresh dialysate and spent dialysate. The balancing system may use one or two balancing devices, such as a balance tube, a tortuous path, or a balance chamber.
    Type: Grant
    Filed: March 30, 2015
    Date of Patent: July 6, 2021
    Assignees: Baxter International Inc., Baxter Healthcare SA
    Inventors: Michael E. Hogard, Donald D. Busby, Robert W. Childers, Yuanpang Samuel Ding, Katherine M. Holian, Mark E. Jablonski, Thomas D. Kelly, Shincy J. Maliekkal, Rodolfo G. Roger, Donald A. Smith, Atif M. Yardimci, Ying-Cheng Lo
  • Patent number: 11052183
    Abstract: The present disclosure provides devices and methods of using same for cleansing a solution (e.g., a salt or used dialysis solution) of urea via electrooxidation, and more specifically to cleansing a renal therapy solution/dialysis solution of urea via electrooxidation so that the renal therapy solution/dialysis solution can be used or reused for treatment of a patient. In an embodiment, a device for the removal of urea from a fluid having urea to produce a cleansed fluid includes a urea decomposition unit and an electrodialysis unit.
    Type: Grant
    Filed: August 26, 2019
    Date of Patent: July 6, 2021
    Assignees: Baxter International Inc., Baxter Healthcare SA
    Inventors: Yuanpang Samuel Ding, Cristian Adolfo Menzel Bueno, Rosa Yeh
  • Patent number: 11045595
    Abstract: A dialysis system is configured to enable a patient to undergo both peritoneal dialysis and extracorporeal blood treatments. The example dialysis system includes a base unit configurable to provide a first fluid for use in preforming at least one peritoneal dialysis treatment at a first time. The base unit is further configurable to provide a second, different fluid for use in at least one extracorporeal blood treatment at a second, different time. The example dialysis system also includes a blood treatment unit configured to be docked to the base unit. The blood treatment unit includes a blood pump configured to pump blood from the patient to a blood filter and from the blood filter back to the patient. The blood filter or a blood line in communication with the blood filter receives the second fluid from the base unit for use in the at least one extracorporeal blood treatment.
    Type: Grant
    Filed: November 30, 2017
    Date of Patent: June 29, 2021
    Assignees: Baxter International Inc., Baxter Healthcare SA
    Inventors: Gino Cicchello, Christian Bernard, Robert W. Childers, Anthony Simiele
  • Patent number: 11045094
    Abstract: The invention provides a neck-worn sensor for simultaneously measuring a blood pressure (BP), pulse oximetry (SpO2), and other vital signs and hemodynamic parameters from a patient. The neck-worn sensor features a sensing portion having a flexible housing that is worn entirely on the patient's chest and encloses a battery, wireless transmitter, and all the sensor's sensing and electronic components. It measures electrocardiogram (ECG), impedance plethysmogram (IPG), photoplethysmogram (PPG), and phonocardiogram (PCG) waveforms, and collectively processes these to determine the vital signs and hemodynamic parameters. The sensor that measures PPG waveforms also includes a heating element to increase perfusion of tissue on the chest.
    Type: Grant
    Filed: July 24, 2018
    Date of Patent: June 29, 2021
    Assignees: BAXTER INTERNATIONAL INC., BAXTER HEALTHCARE SA
    Inventors: Erik Tang, Matthew Banet, Marshal Dhillon, James McCanna
  • Patent number: 11039753
    Abstract: Devices, systems, and methods for monitoring patient hemodynamic status, systemic vascular resistance, reversal of cardiac and respiratory rates, and patient respiratory volume or effort are disclosed. A peripheral venous pressure is measured and used to detect levels, changes, or problems relating to patient blood volume. The peripheral venous pressure measurement is transformed from the time domain to the frequency domain for analysis. A heart rate frequency is identified, and harmonics of the heart rate frequency are detected and evaluated to determine, among other things, hypovolemia or hypervolemia, systemic vascular resistance, and of cardiac and respiratory rates, and patient respiratory volume or effort.
    Type: Grant
    Filed: December 15, 2017
    Date of Patent: June 22, 2021
    Assignees: BAXTER INTERNATIONAL INC., BAXTER HEALTHCARE SA
    Inventors: Jonathan Handler, James Martucci, Kyle Hocking, Susan Eagle, Colleen Brophy, Richard Boyer, Franz Baudenbacher
  • Patent number: D924157
    Type: Grant
    Filed: January 29, 2020
    Date of Patent: July 6, 2021
    Assignees: Baxter International Inc., Baxter Healthcare SA
    Inventors: Yochay Kaplan, Baruch Levy, Eliezer Schusman, Mordechai Dinour