Patents Assigned to Bayer Aktiengesellschaft
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Publication number: 20220198234Abstract: Please substitute the following paragraph(s) for the abstract now appearing in the currently filed specification: The present disclosure relates to the tracking of objects. Objects of the present invention are a method, a system and a computer program product for tracking objects.Type: ApplicationFiled: November 27, 2019Publication date: June 23, 2022Applicant: Bayer AktiengesellschaftInventor: Johannes DEMMER
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Publication number: 20220192189Abstract: The present invention relates to agrochemical compositions: their use for foliar application; their use at low spray volumes; their use by unmanned aerial systems (UAS), unmanned guided vehicles (UGV), and tractor mounted boom sprayers fitted with conventional nozzles but also pulse width modulation spray nozzles or rotating disc droplet applicators; and their application for controlling agricultural pests, weeds or diseases, in particular on waxy leaves.Type: ApplicationFiled: May 8, 2020Publication date: June 23, 2022Applicant: Bayer AktiengesellschaftInventors: Malcolm FAERS, Emilia HILZ, Sybille LAMPRECHT
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Publication number: 20220192188Abstract: The present invention relates to agrochemical compositions: their use for foliar application; their use at low spray volumes; their use by unmanned aerial systems (UAS), unmanned guided vehicles (UGV), and tractor mounted boom sprayers fitted with conventional nozzles but also pulse width modulation spray nozzles or rotating disc droplet applicators; and their application for controlling agricultural pests, weeds or diseases, in particular on waxy leaves.Type: ApplicationFiled: May 8, 2020Publication date: June 23, 2022Applicant: Bayer AktiengesellschaftInventors: Arno RATSCHINSKI, Andreas RÖCHLING, Malcolm FAERS, Emilia HILZ, Elisabech ASMUS, Udo BICKERS
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Patent number: 11365179Abstract: The present invention provides methods for the preparation of Compound (I): Compound (I), the use of intermediates for the preparation of said compound and its crystalline form A.Type: GrantFiled: April 3, 2019Date of Patent: June 21, 2022Assignees: BAYER AKTIENGESELLSCHAFT, BAYER PHARMA AKTIENGESELLSCHAFTInventors: Jorma Hassfeld, Stefan Nikolaus Gradl, Philipp Rubenbauer, Henricus Nicolaas Sebastiaan Van Der Haas, Reinerus Gerardus Gieling
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Publication number: 20220189587Abstract: A method of generating codes for chemical structures from NMR spectroscopy data comprises receiving spectroscopic data of a chemical compound, inputting the spectroscopic data into a first artificial neural network to generate molecular descriptors, receiving a molecular descriptor from the first artificial neural network, inputting the molecular descriptor a second artificial neural network to convert structure data of the chemical reference compounds to molecular descriptors and to convert the molecular descriptors back to the structure data, and receiving structure data of the chemical compound from the second artificial neural network.Type: ApplicationFiled: December 15, 2021Publication date: June 16, 2022Applicant: Bayer AktiengesellschaftInventors: Djork-Arne CLEVERT, Jan Robin WINTER
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Publication number: 20220178805Abstract: The present disclosure relates to the determination of the rheological behavior of a fluid.Type: ApplicationFiled: April 23, 2020Publication date: June 9, 2022Applicant: Bayer AktiengesellschaftInventor: Gary SIMMONS
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Patent number: 11350633Abstract: The present invention relates to a method for controlling phytopathogenic fungi of the genus Phoma spp. and Verticillium spp. comprising applying Coniothyrium minitans strain CON/M/91-08 or a mutant having all identifying characteristics of the respective strain in an effective amount to the root system of a plant, to harvest residues or to the soil on which a crop plant grows or is intended to grow. Also disclosed is the use of said strain for controlling phytopathogenic fungi of the genus Phoma spp. and Verticillium spp.Type: GrantFiled: November 14, 2017Date of Patent: June 7, 2022Assignee: Bayer AktiengesellschaftInventor: Karel Riha
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Publication number: 20220169618Abstract: Described are substituted 2-heteroarylaminobenzenes of the general formula (I) and their use as herbicides, in particular for controlling broad-leaved weeds and/or weed grasses in crops of useful plants and/or as plant growth regulators for influencing the growth of crops of useful plants. The present invention further relates to herbicidal and/or plant growth-regulating compositions comprising one or more compounds of the general formula (I).Type: ApplicationFiled: March 23, 2020Publication date: June 2, 2022Applicant: Bayer AktiengesellschaftInventors: Ralf BRAUN, Michael Charles MCLEOD, Alexandra MANOS-TURVEY, David Michael BARBER, Harald JAKOBI, Dirk SCHMUTZLER, Anu Bheemaiah MACHETTIRA, Elisabeth ASMUS
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Publication number: 20220169736Abstract: The present invention relates to an anti-ILDR2 antibody, a fragment or derivative thereof, a modified antibody format, or an antibody mimetic for use in combination with a PD-1 antagonist in the treatment of cancer. Other aspects of the present invention relate to a combination comprising an anti-ILDR2 antibody and a PD-1 antagonist and the use of such combination as a medicament, as well as methods of treatment or prophylaxis of a cancer in a subject, comprising administering to said subject a therapeutically effective amount of the antibodies as described herein. Further, the present invention relates to a kit comprising anti-ILDR2 antibodies and PD-1 antagonists and optionally one or more further pharmaceutical agents.Type: ApplicationFiled: April 6, 2020Publication date: June 2, 2022Applicants: Bayer Aktiengesellschaft, Compugen LTD.Inventors: Lars RÖSE, Uwe GRITZAN, Spencer LIANG, Andrew POW, John HUNTER, Ofer LEVY, Ilan VAKNIN
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Patent number: 11344519Abstract: The present invention relates to orally administrable modified-release pharmaceutical dosage forms comprising sodium (3S)-3-(4-chloro-3-{[(2S,3R)-2-(4-chlorophenyl)-4,4,4-trifluoro-3-methylbutanoyl]amino}phenyl)-3-cyclopropylpropanoate and to processes for preparing the dosage forms and to their use for the treatment and/or prevention of diseases, in particular for the treatment and/or prevention of cardiac, renal and pulmonary disorders, disorders of the central nervous system, fibrotic and inflammatory disorders and metabolic disorders.Type: GrantFiled: December 23, 2020Date of Patent: May 31, 2022Assignees: BAYER PHARMA AKTIENGESELLSCHAFT, BAYER AKTIENGESELLSCHAFTInventors: Anke Stroyer, Carmen Lobback, Peter Serno, Philipp Rubenbauer, Kai Lovis, Heiko Schirmer, Danja Grossbach, Donald Bierer, Britta Olenik, Tia Jacobs, Julia Küsel
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Publication number: 20220164745Abstract: An apparatus for supply-chain management includes memory storing application software coupled with an enterprise resource planning (ERP) system and processing circuitry configured execute the application software. Executing the application software causes the apparatus to generate a graphical user interface (GUI). The apparatus initiates a planning module of the GUI to build a portfolio including products and a customer, select a product, input a purchase plan, perform an analysis of the purchase plan, and output the purchase plan to a collaboration module. The apparatus initiates the collaboration module to generate a supply plan based on the purchase plan, compare the purchase plan and the supply plan to data received from the ERP system, modify the purchase plan and the supply plan, and output the modified plans to a deviation management module. The apparatus initiates the deviation management module to determine whether the modified purchase plan should be adjusted.Type: ApplicationFiled: April 6, 2020Publication date: May 26, 2022Applicant: Bayer AktiengesellschaftInventors: Gregory DIBBLE, Frank GÜMMER, Mark SOUTHGATE, Tao WANG, Vedad Boberg FAZLIC, Verena SCHMID, Jean-Remi MEUNIER
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Patent number: 11339157Abstract: Compounds of formula (I) processes for their production and their use as pharmaceuticals.Type: GrantFiled: October 23, 2018Date of Patent: May 24, 2022Assignees: Bayer Aktiengesellschaft, Bayer Pharma Aktiengesellschaft, Dana-Farber Cancer Institute, Inc., The Broad Institute, Inc.Inventors: Stephan Siegel, Franziska Siegel, Volker Schulze, Markus Berger, Keith Graham, Ulrich Klar, Knut Eis, Detlev Sülzle, Ulf Bömer, Daniel Korr, Kirstin Petersen, Ursula Mönning, Uwe Eberspächer, Dieter Moosmayer, Matthew Meyerson, Heidi Greulich, Bethany Kaplan, Hassan Youssef Harb, Phi Manh Dinh
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Patent number: 11339137Abstract: The present invention relates to a novel, one-stage method for preparing and isolating 3,4-dichloro-N-(2-cyanophenyl)-5-isothiazolecarboxamide (isotianil), which has microbicidal and plant-fortifying (host defence inducer) properties. In the method according to the invention, the amount of waste from the production process (e.g. solvent) is significantly reduced. The product is provided in high yield and purity (minimal amount of by-products and impurities). Compared to existing preparation methods, the method according to the invention has the advantage of low corrosiveness and high yield and high selectivity.Type: GrantFiled: April 2, 2019Date of Patent: May 24, 2022Assignees: Bayer Aktiengesellschaft, Bayer CropScience AktiengesellschaftInventors: Taraneh Farida, Martin Littmann, Ali Sanli, Kyra Larissa Pabst, Juergen Ludwig, Albert Schnatterer
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Patent number: 11337973Abstract: The invention relates to prolyl endopeptidase (PREP) inhibitors of formula (I) which contain a condensed 2,4-dihydro-3H-1,2,4-triazol-3-one ring system, methods for producing same, the use thereof alone or in combinations for treating and/or preventing diseases, and the use thereof for producing drugs for treating and/or preventing diseases, in particular for treating and/or preventing inflammatory lung diseases (COPD).Type: GrantFiled: October 31, 2018Date of Patent: May 24, 2022Assignees: Bayer Aktiengesellschaft, Bayer Pharma AktiengesellschaftInventors: Nicole Biber, Damian Brockschnieder, Florian Kölling, Jörg Meding, Hideki Miyatake Ondozabal, Thomas Neubauer, Martina Schäfer, Dmitry Zubov, Carsten Terjung
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Patent number: 11339155Abstract: The invention relates to novel compounds of the formula (I) in which R1, R2, R3, R4, R5, R6, R7, R8, A1, A2, A3 and n each have the meanings given above, to their use as acaricides and/or insecticides for controlling animal pests and to processes and intermediates for their preparation.Type: GrantFiled: September 28, 2017Date of Patent: May 24, 2022Assignees: Bayer CropScience Aktiengesellschaft, Bayer AktiengesellschaftInventors: Ruediger Fischer, Dominik Hager, Laura Hoffmeister, Nina Kausch-Busies, Marc Mosrin, David Wilcke, Matthieu Willot, Kerstin Ilg, Daniela Portz, Ulrich Goergens, Andreas Turberg
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Publication number: 20220153417Abstract: An unmanned aerial vehicle for application of an active ingredient to agricultural crops is configured to hold: a liquid comprising the active ingredient in at least one liquid reservoir housed within or attached to the unmanned aerial vehicle. At least one liquid application unit is housed within or attached to the unmanned aerial vehicle and in fluid communication with the at least one liquid reservoir. The housing of at least one sensor unit which is configured to determine sense information comprising sensing a functioning of one or more of: the at least one liquid reservoir, the at least one liquid application unit, the at least one operating unit. A processing unit determines an instruction to the unmanned aerial vehicle to dock with a base station and get a service from the base station. This determination step comprises utilization of sense information.Type: ApplicationFiled: March 9, 2020Publication date: May 19, 2022Applicant: Bayer AktiengesellschaftInventors: Malcolm FAERS, Andrew Charles CHAPPLE
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Patent number: 11332447Abstract: The present invention relates to a process for preparing compounds of the formula (I) by halogenating compounds of the formula (II), where in R1, R2, R3 and X are defined according to the invention.Type: GrantFiled: May 20, 2019Date of Patent: May 17, 2022Assignee: Bayer AktiengesellschaftInventors: Andreas Rembiak, Eike Kevin Heilmann
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Publication number: 20220133888Abstract: The present invention relates to pharmaceutical compositions and combinations comprising regorafenib or its hydrate, solvate, metabolite or pharmaceutically acceptable salt or a polymorph thereof and a PD-1/PD-L1(2) inhibitor for treating, preventing or managing diseases and conditions including hyperproliferative disorders such as cancer in humans and other mammals.Type: ApplicationFiled: January 14, 2022Publication date: May 5, 2022Applicant: BAYER AKTIENGESELLSCHAFTInventors: Sabine HOFF, Lars RÖSE, Dieter ZOPF, Fabian KIESSLING, Wiltrud LEDERLE, Dennis DOLESCHEL
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INTERFACING WITH A COMPUTER-IMPLEMENTED ENTERPRISE RESOURCE PLANNING SYSTEM FOR INVENTORY MANAGEMENT
Publication number: 20220138782Abstract: A method is provided for inventory management from an apparatus with application software coupled with an enterprise resource planning (ERP) system and a back-office support system via respective middleware. The method includes the apparatus accessing and receiving a bill of lading from the ERP system and executing a questionnaire in a graphical user interface (GUI) to gather user input that indicates a quantity of received products relative to a quantity of the shipped products. The questionnaire includes logic that controls which questions are presented in the GUI and in what sequence. The apparatus determines if the quantities of received and shipped products match based on the bill of lading and the user input. And the apparatus records the receipt of the shipment in the ERP system or sends a notification to the back-office support system, depending on whether the quantities match or deviate from one another.Type: ApplicationFiled: February 27, 2020Publication date: May 5, 2022Applicant: Bayer AktiengesellschaftInventors: Gregory DIBBLE, Mark SOUTHGATE, Angela WILSON, Tao WANG, Frank GÜMMER -
Publication number: 20220135536Abstract: The present invention provides triazolone compounds of general formula (I): in which R1, R2, R3, R4, and R5 are as defined herein, methods of preparing said compounds, intermediate compounds useful for preparing said compounds, pharmaceutical compositions and combinations comprising said compounds and the use of said compounds for manufacturing pharmaceutical compositions for the treatment and prophylaxis of diseases, in particular hyperproliferative disorders, as a sole agent or in combination with other active ingredients.Type: ApplicationFiled: August 20, 2021Publication date: May 5, 2022Applicants: BAYER AKTIENGESELLSCHAFT, BAYER PHARMA AKTIENGELLSCHAFT, THE BROAD INSTITUTE, INC., PRESIDENT AND FELLOWS OF HARVARD COLLEGE, THE GENERAL HOSPITAL CORPORATIONInventors: Stefan Nikolaus GRADL, Duy NGUYEN, Knut EIS, Judith GÜNTHER, Timo STELLFELD, Andreas JANZER, Sven CHRISTIAN, Thomas MÜLLER, Sherif El SHEIKH, David B. SYKES, Steven James FERRARA, Michael KRÖBER, Claudia MERZ, Michael NIEHUES, Martina SCHÄFER, Katja ZIMMERMANN, Carl Friedrich NISING