Patents Assigned to Bayer Aktiengesellschaft
  • Publication number: 20220198234
    Abstract: Please substitute the following paragraph(s) for the abstract now appearing in the currently filed specification: The present disclosure relates to the tracking of objects. Objects of the present invention are a method, a system and a computer program product for tracking objects.
    Type: Application
    Filed: November 27, 2019
    Publication date: June 23, 2022
    Applicant: Bayer Aktiengesellschaft
    Inventor: Johannes DEMMER
  • Publication number: 20220192189
    Abstract: The present invention relates to agrochemical compositions: their use for foliar application; their use at low spray volumes; their use by unmanned aerial systems (UAS), unmanned guided vehicles (UGV), and tractor mounted boom sprayers fitted with conventional nozzles but also pulse width modulation spray nozzles or rotating disc droplet applicators; and their application for controlling agricultural pests, weeds or diseases, in particular on waxy leaves.
    Type: Application
    Filed: May 8, 2020
    Publication date: June 23, 2022
    Applicant: Bayer Aktiengesellschaft
    Inventors: Malcolm FAERS, Emilia HILZ, Sybille LAMPRECHT
  • Publication number: 20220192188
    Abstract: The present invention relates to agrochemical compositions: their use for foliar application; their use at low spray volumes; their use by unmanned aerial systems (UAS), unmanned guided vehicles (UGV), and tractor mounted boom sprayers fitted with conventional nozzles but also pulse width modulation spray nozzles or rotating disc droplet applicators; and their application for controlling agricultural pests, weeds or diseases, in particular on waxy leaves.
    Type: Application
    Filed: May 8, 2020
    Publication date: June 23, 2022
    Applicant: Bayer Aktiengesellschaft
    Inventors: Arno RATSCHINSKI, Andreas RÖCHLING, Malcolm FAERS, Emilia HILZ, Elisabech ASMUS, Udo BICKERS
  • Patent number: 11365179
    Abstract: The present invention provides methods for the preparation of Compound (I): Compound (I), the use of intermediates for the preparation of said compound and its crystalline form A.
    Type: Grant
    Filed: April 3, 2019
    Date of Patent: June 21, 2022
    Assignees: BAYER AKTIENGESELLSCHAFT, BAYER PHARMA AKTIENGESELLSCHAFT
    Inventors: Jorma Hassfeld, Stefan Nikolaus Gradl, Philipp Rubenbauer, Henricus Nicolaas Sebastiaan Van Der Haas, Reinerus Gerardus Gieling
  • Publication number: 20220189587
    Abstract: A method of generating codes for chemical structures from NMR spectroscopy data comprises receiving spectroscopic data of a chemical compound, inputting the spectroscopic data into a first artificial neural network to generate molecular descriptors, receiving a molecular descriptor from the first artificial neural network, inputting the molecular descriptor a second artificial neural network to convert structure data of the chemical reference compounds to molecular descriptors and to convert the molecular descriptors back to the structure data, and receiving structure data of the chemical compound from the second artificial neural network.
    Type: Application
    Filed: December 15, 2021
    Publication date: June 16, 2022
    Applicant: Bayer Aktiengesellschaft
    Inventors: Djork-Arne CLEVERT, Jan Robin WINTER
  • Publication number: 20220178805
    Abstract: The present disclosure relates to the determination of the rheological behavior of a fluid.
    Type: Application
    Filed: April 23, 2020
    Publication date: June 9, 2022
    Applicant: Bayer Aktiengesellschaft
    Inventor: Gary SIMMONS
  • Patent number: 11350633
    Abstract: The present invention relates to a method for controlling phytopathogenic fungi of the genus Phoma spp. and Verticillium spp. comprising applying Coniothyrium minitans strain CON/M/91-08 or a mutant having all identifying characteristics of the respective strain in an effective amount to the root system of a plant, to harvest residues or to the soil on which a crop plant grows or is intended to grow. Also disclosed is the use of said strain for controlling phytopathogenic fungi of the genus Phoma spp. and Verticillium spp.
    Type: Grant
    Filed: November 14, 2017
    Date of Patent: June 7, 2022
    Assignee: Bayer Aktiengesellschaft
    Inventor: Karel Riha
  • Publication number: 20220169618
    Abstract: Described are substituted 2-heteroarylaminobenzenes of the general formula (I) and their use as herbicides, in particular for controlling broad-leaved weeds and/or weed grasses in crops of useful plants and/or as plant growth regulators for influencing the growth of crops of useful plants. The present invention further relates to herbicidal and/or plant growth-regulating compositions comprising one or more compounds of the general formula (I).
    Type: Application
    Filed: March 23, 2020
    Publication date: June 2, 2022
    Applicant: Bayer Aktiengesellschaft
    Inventors: Ralf BRAUN, Michael Charles MCLEOD, Alexandra MANOS-TURVEY, David Michael BARBER, Harald JAKOBI, Dirk SCHMUTZLER, Anu Bheemaiah MACHETTIRA, Elisabeth ASMUS
  • Publication number: 20220169736
    Abstract: The present invention relates to an anti-ILDR2 antibody, a fragment or derivative thereof, a modified antibody format, or an antibody mimetic for use in combination with a PD-1 antagonist in the treatment of cancer. Other aspects of the present invention relate to a combination comprising an anti-ILDR2 antibody and a PD-1 antagonist and the use of such combination as a medicament, as well as methods of treatment or prophylaxis of a cancer in a subject, comprising administering to said subject a therapeutically effective amount of the antibodies as described herein. Further, the present invention relates to a kit comprising anti-ILDR2 antibodies and PD-1 antagonists and optionally one or more further pharmaceutical agents.
    Type: Application
    Filed: April 6, 2020
    Publication date: June 2, 2022
    Applicants: Bayer Aktiengesellschaft, Compugen LTD.
    Inventors: Lars RÖSE, Uwe GRITZAN, Spencer LIANG, Andrew POW, John HUNTER, Ofer LEVY, Ilan VAKNIN
  • Patent number: 11344519
    Abstract: The present invention relates to orally administrable modified-release pharmaceutical dosage forms comprising sodium (3S)-3-(4-chloro-3-{[(2S,3R)-2-(4-chlorophenyl)-4,4,4-trifluoro-3-methylbutanoyl]amino}phenyl)-3-cyclopropylpropanoate and to processes for preparing the dosage forms and to their use for the treatment and/or prevention of diseases, in particular for the treatment and/or prevention of cardiac, renal and pulmonary disorders, disorders of the central nervous system, fibrotic and inflammatory disorders and metabolic disorders.
    Type: Grant
    Filed: December 23, 2020
    Date of Patent: May 31, 2022
    Assignees: BAYER PHARMA AKTIENGESELLSCHAFT, BAYER AKTIENGESELLSCHAFT
    Inventors: Anke Stroyer, Carmen Lobback, Peter Serno, Philipp Rubenbauer, Kai Lovis, Heiko Schirmer, Danja Grossbach, Donald Bierer, Britta Olenik, Tia Jacobs, Julia Küsel
  • Publication number: 20220164745
    Abstract: An apparatus for supply-chain management includes memory storing application software coupled with an enterprise resource planning (ERP) system and processing circuitry configured execute the application software. Executing the application software causes the apparatus to generate a graphical user interface (GUI). The apparatus initiates a planning module of the GUI to build a portfolio including products and a customer, select a product, input a purchase plan, perform an analysis of the purchase plan, and output the purchase plan to a collaboration module. The apparatus initiates the collaboration module to generate a supply plan based on the purchase plan, compare the purchase plan and the supply plan to data received from the ERP system, modify the purchase plan and the supply plan, and output the modified plans to a deviation management module. The apparatus initiates the deviation management module to determine whether the modified purchase plan should be adjusted.
    Type: Application
    Filed: April 6, 2020
    Publication date: May 26, 2022
    Applicant: Bayer Aktiengesellschaft
    Inventors: Gregory DIBBLE, Frank GÜMMER, Mark SOUTHGATE, Tao WANG, Vedad Boberg FAZLIC, Verena SCHMID, Jean-Remi MEUNIER
  • Patent number: 11339157
    Abstract: Compounds of formula (I) processes for their production and their use as pharmaceuticals.
    Type: Grant
    Filed: October 23, 2018
    Date of Patent: May 24, 2022
    Assignees: Bayer Aktiengesellschaft, Bayer Pharma Aktiengesellschaft, Dana-Farber Cancer Institute, Inc., The Broad Institute, Inc.
    Inventors: Stephan Siegel, Franziska Siegel, Volker Schulze, Markus Berger, Keith Graham, Ulrich Klar, Knut Eis, Detlev Sülzle, Ulf Bömer, Daniel Korr, Kirstin Petersen, Ursula Mönning, Uwe Eberspächer, Dieter Moosmayer, Matthew Meyerson, Heidi Greulich, Bethany Kaplan, Hassan Youssef Harb, Phi Manh Dinh
  • Patent number: 11339137
    Abstract: The present invention relates to a novel, one-stage method for preparing and isolating 3,4-dichloro-N-(2-cyanophenyl)-5-isothiazolecarboxamide (isotianil), which has microbicidal and plant-fortifying (host defence inducer) properties. In the method according to the invention, the amount of waste from the production process (e.g. solvent) is significantly reduced. The product is provided in high yield and purity (minimal amount of by-products and impurities). Compared to existing preparation methods, the method according to the invention has the advantage of low corrosiveness and high yield and high selectivity.
    Type: Grant
    Filed: April 2, 2019
    Date of Patent: May 24, 2022
    Assignees: Bayer Aktiengesellschaft, Bayer CropScience Aktiengesellschaft
    Inventors: Taraneh Farida, Martin Littmann, Ali Sanli, Kyra Larissa Pabst, Juergen Ludwig, Albert Schnatterer
  • Patent number: 11337973
    Abstract: The invention relates to prolyl endopeptidase (PREP) inhibitors of formula (I) which contain a condensed 2,4-dihydro-3H-1,2,4-triazol-3-one ring system, methods for producing same, the use thereof alone or in combinations for treating and/or preventing diseases, and the use thereof for producing drugs for treating and/or preventing diseases, in particular for treating and/or preventing inflammatory lung diseases (COPD).
    Type: Grant
    Filed: October 31, 2018
    Date of Patent: May 24, 2022
    Assignees: Bayer Aktiengesellschaft, Bayer Pharma Aktiengesellschaft
    Inventors: Nicole Biber, Damian Brockschnieder, Florian Kölling, Jörg Meding, Hideki Miyatake Ondozabal, Thomas Neubauer, Martina Schäfer, Dmitry Zubov, Carsten Terjung
  • Patent number: 11339155
    Abstract: The invention relates to novel compounds of the formula (I) in which R1, R2, R3, R4, R5, R6, R7, R8, A1, A2, A3 and n each have the meanings given above, to their use as acaricides and/or insecticides for controlling animal pests and to processes and intermediates for their preparation.
    Type: Grant
    Filed: September 28, 2017
    Date of Patent: May 24, 2022
    Assignees: Bayer CropScience Aktiengesellschaft, Bayer Aktiengesellschaft
    Inventors: Ruediger Fischer, Dominik Hager, Laura Hoffmeister, Nina Kausch-Busies, Marc Mosrin, David Wilcke, Matthieu Willot, Kerstin Ilg, Daniela Portz, Ulrich Goergens, Andreas Turberg
  • Publication number: 20220153417
    Abstract: An unmanned aerial vehicle for application of an active ingredient to agricultural crops is configured to hold: a liquid comprising the active ingredient in at least one liquid reservoir housed within or attached to the unmanned aerial vehicle. At least one liquid application unit is housed within or attached to the unmanned aerial vehicle and in fluid communication with the at least one liquid reservoir. The housing of at least one sensor unit which is configured to determine sense information comprising sensing a functioning of one or more of: the at least one liquid reservoir, the at least one liquid application unit, the at least one operating unit. A processing unit determines an instruction to the unmanned aerial vehicle to dock with a base station and get a service from the base station. This determination step comprises utilization of sense information.
    Type: Application
    Filed: March 9, 2020
    Publication date: May 19, 2022
    Applicant: Bayer Aktiengesellschaft
    Inventors: Malcolm FAERS, Andrew Charles CHAPPLE
  • Patent number: 11332447
    Abstract: The present invention relates to a process for preparing compounds of the formula (I) by halogenating compounds of the formula (II), where in R1, R2, R3 and X are defined according to the invention.
    Type: Grant
    Filed: May 20, 2019
    Date of Patent: May 17, 2022
    Assignee: Bayer Aktiengesellschaft
    Inventors: Andreas Rembiak, Eike Kevin Heilmann
  • Publication number: 20220133888
    Abstract: The present invention relates to pharmaceutical compositions and combinations comprising regorafenib or its hydrate, solvate, metabolite or pharmaceutically acceptable salt or a polymorph thereof and a PD-1/PD-L1(2) inhibitor for treating, preventing or managing diseases and conditions including hyperproliferative disorders such as cancer in humans and other mammals.
    Type: Application
    Filed: January 14, 2022
    Publication date: May 5, 2022
    Applicant: BAYER AKTIENGESELLSCHAFT
    Inventors: Sabine HOFF, Lars RÖSE, Dieter ZOPF, Fabian KIESSLING, Wiltrud LEDERLE, Dennis DOLESCHEL
  • Publication number: 20220138782
    Abstract: A method is provided for inventory management from an apparatus with application software coupled with an enterprise resource planning (ERP) system and a back-office support system via respective middleware. The method includes the apparatus accessing and receiving a bill of lading from the ERP system and executing a questionnaire in a graphical user interface (GUI) to gather user input that indicates a quantity of received products relative to a quantity of the shipped products. The questionnaire includes logic that controls which questions are presented in the GUI and in what sequence. The apparatus determines if the quantities of received and shipped products match based on the bill of lading and the user input. And the apparatus records the receipt of the shipment in the ERP system or sends a notification to the back-office support system, depending on whether the quantities match or deviate from one another.
    Type: Application
    Filed: February 27, 2020
    Publication date: May 5, 2022
    Applicant: Bayer Aktiengesellschaft
    Inventors: Gregory DIBBLE, Mark SOUTHGATE, Angela WILSON, Tao WANG, Frank GÜMMER
  • Publication number: 20220135536
    Abstract: The present invention provides triazolone compounds of general formula (I): in which R1, R2, R3, R4, and R5 are as defined herein, methods of preparing said compounds, intermediate compounds useful for preparing said compounds, pharmaceutical compositions and combinations comprising said compounds and the use of said compounds for manufacturing pharmaceutical compositions for the treatment and prophylaxis of diseases, in particular hyperproliferative disorders, as a sole agent or in combination with other active ingredients.
    Type: Application
    Filed: August 20, 2021
    Publication date: May 5, 2022
    Applicants: BAYER AKTIENGESELLSCHAFT, BAYER PHARMA AKTIENGELLSCHAFT, THE BROAD INSTITUTE, INC., PRESIDENT AND FELLOWS OF HARVARD COLLEGE, THE GENERAL HOSPITAL CORPORATION
    Inventors: Stefan Nikolaus GRADL, Duy NGUYEN, Knut EIS, Judith GÜNTHER, Timo STELLFELD, Andreas JANZER, Sven CHRISTIAN, Thomas MÜLLER, Sherif El SHEIKH, David B. SYKES, Steven James FERRARA, Michael KRÖBER, Claudia MERZ, Michael NIEHUES, Martina SCHÄFER, Katja ZIMMERMANN, Carl Friedrich NISING